Publications by authors named "William R Bamlet"

97Publications

Mendelian Randomization Analysis of n-6 Polyunsaturated Fatty Acid Levels and Pancreatic Cancer Risk.

Cancer Epidemiol Biomarkers Prev 2020 Sep 23. Epub 2020 Sep 23.

Division of Cancer Epidemiology, Population Sciences in the Pacific Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.

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http://dx.doi.org/10.1158/1055-9965.EPI-20-0651DOI Listing
September 2020

Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk.

Cancer Res 2020 Sep 8;80(18):4004-4013. Epub 2020 Jul 8.

Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-20-0447DOI Listing
September 2020

Genome-Wide Gene-Diabetes and Gene-Obesity Interaction Scan in 8,255 Cases and 11,900 Controls from PanScan and PanC4 Consortia.

Cancer Epidemiol Biomarkers Prev 2020 Sep 16;29(9):1784-1791. Epub 2020 Jun 16.

Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1055-9965.EPI-20-0275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7483330PMC
September 2020

Dynamin 2 interacts with α-actinin 4 to drive tumor cell invasion.

Mol Biol Cell 2020 03 22;31(6):439-451. Epub 2020 Jan 22.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905.

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http://dx.doi.org/10.1091/mbc.E19-07-0395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7185896PMC
March 2020

A Transcriptome-Wide Association Study Identifies Novel Candidate Susceptibility Genes for Pancreatic Cancer.

J Natl Cancer Inst 2020 Oct;112(10):1003-1012

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/jnci/djz246DOI Listing
October 2020

Agnostic Pathway/Gene Set Analysis of Genome-Wide Association Data Identifies Associations for Pancreatic Cancer.

Authors:
Naomi Walsh Han Zhang Paula L Hyland Qi Yang Evelina Mocci Mingfeng Zhang Erica J Childs Irene Collins Zhaoming Wang Alan A Arslan Laura Beane-Freeman Paige M Bracci Paul Brennan Federico Canzian Eric J Duell Steven Gallinger Graham G Giles Michael Goggins Gary E Goodman Phyllis J Goodman Rayjean J Hung Charles Kooperberg Robert C Kurtz Núria Malats Loic LeMarchand Rachel E Neale Sara H Olson Ghislaine Scelo Xiao O Shu Stephen K Van Den Eeden Kala Visvanathan Emily White Wei Zheng Demetrius Albanes Gabriella Andreotti Ana Babic William R Bamlet Sonja I Berndt Ayelet Borgida Marie-Christine Boutron-Ruault Lauren Brais Paul Brennan Bas Bueno-de-Mesquita Julie Buring Kari G Chaffee Stephen Chanock Sean Cleary Michelle Cotterchio Lenka Foretova Charles Fuchs J Michael M Gaziano Edward Giovannucci Michael Goggins Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Vladimir Janout Eric A Klein Robert C Kurtz Daniel Laheru I-Min Lee Lingeng Lu Núria Malats Satu Mannisto Roger L Milne Ann L Oberg Irene Orlow Alpa V Patel Ulrike Peters Miquel Porta Francisco X Real Nathaniel Rothman Howard D Sesso Gianluca Severi Debra Silverman Oliver Strobel Malin Sund Mark D Thornquist Geoffrey S Tobias Jean Wactawski-Wende Nick Wareham Elisabete Weiderpass Nicolas Wentzensen William Wheeler Herbert Yu Anne Zeleniuch-Jacquotte Peter Kraft Donghui Li Eric J Jacobs Gloria M Petersen Brian M Wolpin Harvey A Risch Laufey T Amundadottir Kai Yu Alison P Klein Rachael Z Stolzenberg-Solomon

J Natl Cancer Inst 2019 Jun;111(6):557-567

National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin, Ireland.

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https://academic.oup.com/jnci/advance-article/doi/10.1093/jn
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http://dx.doi.org/10.1093/jnci/djy155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579744PMC
June 2019

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer.

Authors:
Alison P Klein Brian M Wolpin Harvey A Risch Rachael Z Stolzenberg-Solomon Evelina Mocci Mingfeng Zhang Federico Canzian Erica J Childs Jason W Hoskins Ashley Jermusyk Jun Zhong Fei Chen Demetrius Albanes Gabriella Andreotti Alan A Arslan Ana Babic William R Bamlet Laura Beane-Freeman Sonja I Berndt Amanda Blackford Michael Borges Ayelet Borgida Paige M Bracci Lauren Brais Paul Brennan Hermann Brenner Bas Bueno-de-Mesquita Julie Buring Daniele Campa Gabriele Capurso Giulia Martina Cavestro Kari G Chaffee Charles C Chung Sean Cleary Michelle Cotterchio Frederike Dijk Eric J Duell Lenka Foretova Charles Fuchs Niccola Funel Steven Gallinger J Michael M Gaziano Maria Gazouli Graham G Giles Edward Giovannucci Michael Goggins Gary E Goodman Phyllis J Goodman Thilo Hackert Christopher Haiman Patricia Hartge Manal Hasan Peter Hegyi Kathy J Helzlsouer Joseph Herman Ivana Holcatova Elizabeth A Holly Robert Hoover Rayjean J Hung Eric J Jacobs Krzysztof Jamroziak Vladimir Janout Rudolf Kaaks Kay-Tee Khaw Eric A Klein Manolis Kogevinas Charles Kooperberg Matthew H Kulke Juozas Kupcinskas Robert J Kurtz Daniel Laheru Stefano Landi Rita T Lawlor I-Min Lee Loic LeMarchand Lingeng Lu Núria Malats Andrea Mambrini Satu Mannisto Roger L Milne Beatrice Mohelníková-Duchoňová Rachel E Neale John P Neoptolemos Ann L Oberg Sara H Olson Irene Orlow Claudio Pasquali Alpa V Patel Ulrike Peters Raffaele Pezzilli Miquel Porta Francisco X Real Nathaniel Rothman Ghislaine Scelo Howard D Sesso Gianluca Severi Xiao-Ou Shu Debra Silverman Jill P Smith Pavel Soucek Malin Sund Renata Talar-Wojnarowska Francesca Tavano Mark D Thornquist Geoffrey S Tobias Stephen K Van Den Eeden Yogesh Vashist Kala Visvanathan Pavel Vodicka Jean Wactawski-Wende Zhaoming Wang Nicolas Wentzensen Emily White Herbert Yu Kai Yu Anne Zeleniuch-Jacquotte Wei Zheng Peter Kraft Donghui Li Stephen Chanock Ofure Obazee Gloria M Petersen Laufey T Amundadottir

Nat Commun 2018 02 8;9(1):556. Epub 2018 Feb 8.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41467-018-02942-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805680PMC
February 2018

Quantifying Effect of Onabotulinum Toxin A on Passive Muscle Stiffness in Children with Cerebral Palsy Using Ultrasound Shear Wave Elastography.

Am J Phys Med Rehabil 2018 07;97(7):500-506

From the Department of Physical Medicine and Rehabilitation (JEB), Department of Neurology (JEB), Department of Pediatric and Adolescent Medicine (JEB), Mayo Graduate School, Medical Scientist Training Program, Mayo Clinic College of Medicine (SFE), Department of Radiology (PS), Department of Health Sciences Research (WRB), Department of Physiology and Biomedical Engineering (GCS, K-NA), and Division of Orthopedic Research (K-NA), Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1097/PHM.0000000000000907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008180PMC
July 2018

Identification of a pyruvate-to-lactate signature in pancreatic intraductal papillary mucinous neoplasms.

Pancreatology 2018 Jan 14;18(1):46-53. Epub 2017 Nov 14.

Department of Molecular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pan.2017.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139027PMC
January 2018

Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers.

Sci Transl Med 2017 07;9(398)

Institute for Regenerative Medicine, Department of Cell and Developmental Biology, Abramson Cancer Center (Tumor Biology Program), Perelman School of Medicine, University of Pennsylvania, 9-131 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104-5157, USA.

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http://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.aa
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http://dx.doi.org/10.1126/scitranslmed.aah5583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727893PMC
July 2017

Genetically Predicted Telomere Length is not Associated with Pancreatic Cancer Risk.

Cancer Epidemiol Biomarkers Prev 2017 06 6;26(6):971-974. Epub 2017 Mar 6.

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483972PMC
June 2017

Genetic variations associated with gemcitabine treatment outcome in pancreatic cancer.

Pharmacogenet Genomics 2016 Dec;26(12):527-537

aDepartment of Oncology bKey Laboratory of Biotechnology of Antibiotics, the National Health and Family Planning Commission (NHFPC), Institute of Medicinal Biotechnology cDepartment of Abdominal Surgery, Cancer Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, China dDepartment of Molecular Pharmacology and Experimental Therapeutics, Division of Clinical Pharmacology eDepartment of Health Sciences Research, Division of Biomedical Statistics and Informatics fDepartment of Oncology, Mayo Clinic, Rochester, Minnesota gDepartment of Biostatistics, University of Kansas Medical Center, Kansas City, Kansas, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083195PMC
http://dx.doi.org/10.1097/FPC.0000000000000241DOI Listing
December 2016

Metformin Use and Survival of Patients With Pancreatic Cancer: A Cautionary Lesson.

J Clin Oncol 2016 06 11;34(16):1898-904. Epub 2016 Apr 11.

Roongruedee Chaiteerakij and Lewis R. Roberts, Mayo Clinic College of Medicine and Mayo Clinic Cancer Center; Gloria M. Petersen, William R. Bamlet, Kari G. Chaffee, David B. Zhen, Patrick A. Burch, Emma R. Leof, and Ann L. Oberg, Mayo Clinic, Rochester, MN; Roongruedee Chaiteerakij, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand; and David B. Zhen, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1200/JCO.2015.63.3511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966342PMC
June 2016

Pancreatic cancer: associations of inflammatory potential of diet, cigarette smoking and long-standing diabetes.

Carcinogenesis 2016 05 12;37(5):481-90. Epub 2016 Feb 12.

Cancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA.

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http://dx.doi.org/10.1093/carcin/bgw022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843052PMC
May 2016

Risk Factors for Early-Onset and Very-Early-Onset Pancreatic Adenocarcinoma: A Pancreatic Cancer Case-Control Consortium (PanC4) Analysis.

Pancreas 2016 Feb;45(2):311-6

From the *Department of Oncology, Mayo Clinic, Rochester, MN; †Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy; ‡Division of Biostatistics, Mayo Clinic; §Department of Health Sciences Research, Mayo Clinic, Rochester, MN; ∥Department of Gastrointestinal Medical Oncology, UT MD Anderson Cancer Center, Houston, TX; ¶Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT; #Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI; **Louisiana State University School of Public Health, New Orleans, LA; ††Tulane School of Public Health, New Orleans, LA; ‡‡Department of Epidemiology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri," and §§Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy; ∥∥S.O.C. Epidemiologia e Biostatistica, Centro di Riferimento Oncologico, IRCCS, Aviano (PN), Italy; ¶¶National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands; Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands; School of Public Health, Imperial College London, London, United Kingdom; ##Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA; ***Division of General Surgery, University of Toronto, Toronto, Ontario, Canada; †††Cancer and Population Studies Group, QIMR Berghofer Medical Research Institute, Brisbane, Australia; and ‡‡‡Department of Surgery, Department of Family Medicine, New York Medical College, Valhalla, NY.

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http://dx.doi.org/10.1097/MPA.0000000000000392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710562PMC
February 2016

Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.

Cancer Epidemiol Biomarkers Prev 2016 Jan 19;25(1):207-11. Epub 2015 Oct 19.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota. Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754121PMC
January 2016

Impact of Intratumoral Inflammation on Survival After Pancreatic Cancer Resection.

Pancreas 2016 Jan;45(1):123-6

From the *Division of Gastroenterology and Hepatology, †Department of Pathology, ‡Health Sciences Research, Mayo Clinic Rochester, MN.

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http://dx.doi.org/10.1097/MPA.0000000000000423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850490PMC
January 2016

Exposure to environmental chemicals and heavy metals, and risk of pancreatic cancer.

Cancer Causes Control 2015 Nov 21;26(11):1583-91. Epub 2015 Aug 21.

Division of Epidemiology, Health Sciences Research, Mayo Clinic, 200 First Street SW, Charlton 6-243, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s10552-015-0652-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624268PMC
November 2015

Transcriptomic and Immunohistochemical Profiling of SLC6A14 in Pancreatic Ductal Adenocarcinoma.

Biomed Res Int 2015 27;2015:593572. Epub 2015 May 27.

Department of Molecular Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA ; Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1155/2015/593572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461733PMC
March 2016

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer.

Nat Genet 2015 Aug 22;47(8):911-6. Epub 2015 Jun 22.

1] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. [2] Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1038/ng.3341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520746PMC
August 2015

Metformin suppresses pancreatic tumor growth with inhibition of NFκB/STAT3 inflammatory signaling.

Pancreas 2015 May;44(4):636-47

From the *Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN; †Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick; ‡Department of Epidemiology, School of Public Health, Rutgers, The State University of New Jersey, Piscataway, NJ; and §Department of Biochemistry and Molecular Biology, ∥Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, and ¶Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/MPA.0000000000000308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399019PMC
May 2015

Feasibility and reliability of quantifying passive muscle stiffness in young children by using shear wave ultrasound elastography.

J Ultrasound Med 2015 Apr;34(4):663-70

Departments of Physical Medicine and Rehabilitation (J.E.B.), Neurology (J.E.B., B.W.L.), Pediatric and Adolescent Medicine (J.E.B.), Physiology and Biomedical Engineering (P.S., H.Z., S.K.-B., S.C., G.C.S., K.-N.A.), and Health Sciences Research (W.R.B.) and Division of Orthopedic Research (K.-N.A.), Mayo Clinic, Rochester, Minnesota USA; and Mayo Graduate School, Mayo Clinic College of Medicine, Rochester, Minnesota USA (S.F.E.).

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http://dx.doi.org/10.7863/ultra.34.4.663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4369795PMC
April 2015

Risk factors for pancreatic neuroendocrine tumors: a clinic-based case-control study.

Pancreas 2014 Nov;43(8):1219-22

From the *Division of Hematology and Medical Oncology, Mayo Clinic Arizona, Scottsdale, AZ; †Division of Medical Oncology; and ‡Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN.

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http://dx.doi.org/10.1097/MPA.0000000000000234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267883PMC
November 2014

Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A.

Carcinogenesis 2014 Dec 18;35(12):2670-8. Epub 2014 Sep 18.

Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA, Epithelial Carcinogenesis Group, CNIO-Spanish National Cancer Research Centre, E-28029 Madrid, Spain, Lymphoid Malignancies Branch, Center for Cancer Research, National Cancer Institute and Bioinformatics and Molecular Analysis Section, Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, MD 20892, USA, Department of Laboratory Medicine and Pathology and Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA and Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, 08003 Barcelona, Spain

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http://carcin.oxfordjournals.org/content/35/12/2670.full.pdf
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http://www.carcin.oxfordjournals.org/cgi/doi/10.1093/carcin/
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http://dx.doi.org/10.1093/carcin/bgu193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247517PMC
December 2014

Detection of DNA damage in peripheral blood mononuclear cells from pancreatic cancer patients.

Mol Carcinog 2015 Oct 11;54(10):1220-6. Epub 2014 Aug 11.

Department of Physiology and Biophysics, University of Puerto Rico, San Juan, Puerto Rico.

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http://dx.doi.org/10.1002/mc.22189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478243PMC
October 2015

Variation in NF-κB signaling pathways and survival in invasive epithelial ovarian cancer.

Cancer Epidemiol Biomarkers Prev 2014 Jul 16;23(7):1421-7. Epub 2014 Apr 16.

Health Sciences Research, Division of Epidemiology;

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082406PMC
July 2014

Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.

Cancer Discov 2014 Jun 2;4(6):688-701. Epub 2014 Apr 2.

Authors' Affiliations:Signaling and Transcription Laboratory, Department of Gastroenterology, Philipps University, Marburg; Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen; II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität; Institute of Pathology, Helmholtz Zentrum, Munich; Theodor Boveri Institute, University of Würzburg, Würzburg; Institute for Genetics, Justus-Liebig-University, Giessen, Germany; Schulze Center for Novel Therapeutics, Division of Oncology Research; Divisions of Anatomic Pathology and Biostatistics, College of Medicine; Laboratory of Epigenetics and Chromatin Dynamics, Department of Medicine, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota; Barrow Brain Tumor Research Center, St. Joseph's Hospital and Medical Center, Phoenix, Arizona; and Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

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http://dx.doi.org/10.1158/2159-8290.CD-13-0593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069603PMC
June 2014

CLPTM1L promotes growth and enhances aneuploidy in pancreatic cancer cells.

Cancer Res 2014 May 19;74(10):2785-95. Epub 2014 Mar 19.

Authors' Affiliations: Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics; Pediatric Oncology Branch; Laboratory of Pathology; Division of Cancer Control and Population Sciences; Laboratory of Experimental Carcinogenesis, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda; Laboratory of Proteomics and Analytical Technologies, Leidos Biomedical Research, Frederick National Laboratory for Cancer Research; Laboratory of Protein Dynamics and Signaling and Laboratory of Cell & Developmental Signaling, NCI-Frederick, Frederick, Maryland; Keck School of Medicine, University of Southern California, Los Angeles, California; University of Hawaii Cancer Center, Honolulu, Hawaii; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, Iowa; and Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota

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http://dx.doi.org/10.1158/0008-5472.CAN-13-3176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030677PMC
May 2014

Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10.

Authors:
Bridget Charbonneau Matthew S Block William R Bamlet Robert A Vierkant Kimberly R Kalli Zachary Fogarty David N Rider Thomas A Sellers Shelley S Tworoger Elizabeth Poole Harvey A Risch Helga B Salvesen Lambertus A Kiemeney Laura Baglietto Graham G Giles Gianluca Severi Britton Trabert Nicolas Wentzensen Georgia Chenevix-Trench Alice S Whittemore Weiva Sieh Jenny Chang-Claude Elisa V Bandera Irene Orlow Kathryn Terry Marc T Goodman Pamela J Thompson Linda S Cook Mary Anne Rossing Roberta B Ness Steven A Narod Jolanta Kupryjanczyk Karen Lu Ralf Butzow Thilo Dörk Tanja Pejovic Ian Campbell Nhu D Le Clareann H Bunker Natalia Bogdanova Ingo B Runnebaum Diana Eccles James Paul Anna H Wu Simon A Gayther Estrid Hogdall Florian Heitz Stanley B Kaye Beth Y Karlan Hoda Anton-Culver Jacek Gronwald Claus K Hogdall Diether Lambrechts Peter A Fasching Usha Menon Joellen Schildkraut Celeste Leigh Pearce Douglas A Levine Susanne Kruger Kjaer Daniel Cramer James M Flanagan Catherine M Phelan Robert Brown Leon F A G Massuger Honglin Song Jennifer A Doherty Camilla Krakstad Dong Liang Kunle Odunsi Andrew Berchuck Allan Jensen Jan Lubinski Heli Nevanlinna Yukie T Bean Galina Lurie Argyrios Ziogas Christine Walsh Evelyn Despierre Louise Brinton Alexander Hein Anja Rudolph Agnieszka Dansonka-Mieszkowska Sara H Olson Philipp Harter Jonathan Tyrer Allison F Vitonis Angela Brooks-Wilson Katja K Aben Malcolm C Pike Susan J Ramus Elisabeth Wik Cezary Cybulski Jie Lin Lara Sucheston Robert Edwards Valerie McGuire Jenny Lester Andreas du Bois Lene Lundvall Shan Wang-Gohrke Lukasz M Szafron Sandrina Lambrechts Hannah Yang Matthias W Beckmann Liisa M Pelttari Anne M Van Altena David van den Berg Mari K Halle Aleksandra Gentry-Maharaj Ira Schwaab Urmila Chandran Janusz Menkiszak Arif B Ekici Lynne R Wilkens Arto Leminen Francesmary Modugno Grace Friel Joseph H Rothstein Ignace Vergote Montserrat Garcia-Closas Michelle A T Hildebrandt Piotr Sobiczewski Linda E Kelemen Paul D P Pharoah Kirsten Moysich Keith L Knutson Julie M Cunningham Brooke L Fridley Ellen L Goode

Cancer Res 2014 Feb 22;74(3):852-61. Epub 2013 Nov 22.

Authors' Affiliations: Departments of Health Sciences Research, Division of Epidemiology, Medical Oncology, Health Sciences Research, Division of Biomedical Statistics and Informatics, Immunology, and Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, Minnesota; Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida; Channing Division of Network Medicine, Obstetrics and Gynecology Epidemiology Center, Brigham and Women's Hospital, Harvard Medical School; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, Connecticut; Department of Clinical Science, University of Bergen; Departments of Gynecology and Obstetrics, and Pathology, Haukeland University Hospital, Bergen, Norway; Departments for Health Evidence, Urology, and Gynaecology, Radboud University Medical Centre, Nijmegen; Comprehensive Cancer Center The Netherlands, Utrecht, the Netherlands; Cancer Epidemiology Centre, The Cancer Council Victoria; Centre for Molecular, Environmental, Genetic and Analytical Epidemiology, Department of Pathology, and Sir Peter MacCallum Department of Oncology, University of Melbourne; Department of Epidemiology and Preventive Medicine, Monash University; Peter MacCallum Cancer Institute; Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria; Cancer Division, Queensland Institute of Medical Research, Herston, Queensland, Australia; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland; Department of Health Research and Policy, Division of Epidemiology, Stanford University School of Medicine, Palo Alto; Samuel Oschin Comprehensive Cancer Institute; Women's Cancer Program, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center; Department of Preventive Medicine, Keck School of Medicine, University of Sout

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946482PMC
February 2014

An absolute risk model to identify individuals at elevated risk for pancreatic cancer in the general population.

PLoS One 2013 13;8(9):e72311. Epub 2013 Sep 13.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America ; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America ; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772857PMC
June 2014

Polymorphisms in metabolism/antioxidant genes may mediate the effect of dietary intake on pancreatic cancer risk.

Pancreas 2013 Oct;42(7):1043-53

From the Divisions of *Epidemiology, and †Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, MN; ‡Department of Epidemiology, National Institutes of Health, Bethesda, MD; §Department of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN; and ∥Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.

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http://pdfs.journals.lww.com/pancreasjournal/2013/10000/Poly
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http://dx.doi.org/10.1097/MPA.0b013e3182968e00DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779344PMC
October 2013

Meat-related mutagens and pancreatic cancer: null results from a clinic-based case-control study.

Cancer Epidemiol Biomarkers Prev 2013 Jul 30;22(7):1336-9. Epub 2013 Apr 30.

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702664PMC
July 2013

Nutrients from fruit and vegetable consumption reduce the risk of pancreatic cancer.

J Gastrointest Cancer 2013 Jun;44(2):152-61

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1007/s12029-012-9441-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694591PMC
June 2013

Inpatient warfarin management: pharmacist management using a detailed dosing protocol.

J Thromb Thrombolysis 2012 Feb;33(2):178-84

Division of Hospital Internal Medicine, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1007/s11239-011-0655-9DOI Listing
February 2012

Aspirin, nonsteroidal anti-inflammatory drugs, acetaminophen, and pancreatic cancer risk: a clinic-based case-control study.

Cancer Prev Res (Phila) 2011 Nov 29;4(11):1835-41. Epub 2011 Jul 29.

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-11-0146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208748PMC
November 2011

FOUR score and Glasgow Coma Scale in predicting outcome of comatose patients: a pooled analysis.

Neurology 2011 Jul 11;77(1):84-5. Epub 2011 May 11.

Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1212/WNL.0b013e318220ac06DOI Listing
July 2011

Inflammation-related gene variants as risk factors for pancreatic cancer.

Cancer Epidemiol Biomarkers Prev 2011 Jun 5;20(6):1251-4. Epub 2011 Apr 5.

Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111756PMC
June 2011

Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesis.

Cancer Res 2010 Mar 23;70(5):2064-74. Epub 2010 Feb 23.

Department of Cancer Biology, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881466PMC
March 2010

A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.

Nat Genet 2010 Mar 24;42(3):224-8. Epub 2010 Jan 24.

Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/ng.522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853179PMC
March 2010

Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.

Cancer Epidemiol Biomarkers Prev 2010 Jan;19(1):251-7

Department of Laboratory Medicine and Pathology, Stabile 2-42, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805468PMC
January 2010

Association of breast cancer susceptibility variants with risk of pancreatic cancer.

Cancer Epidemiol Biomarkers Prev 2009 Nov 20;18(11):3044-8. Epub 2009 Oct 20.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248348PMC
November 2009

Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.

Cancer Epidemiol Biomarkers Prev 2009 Sep 18;18(9):2549-52. Epub 2009 Aug 18.

Department of Oncology, Mayo Clinic, 200 First Street, Southwest, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742574PMC
September 2009

Nucleotide excision repair pathway polymorphisms and pancreatic cancer risk: evidence for role of MMS19L.

Cancer Epidemiol Biomarkers Prev 2009 Apr 24;18(4):1295-302. Epub 2009 Mar 24.

Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-1109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710767PMC
April 2009

Mitochondrial genetic polymorphisms do not predict survival in patients with pancreatic cancer.

Cancer Epidemiol Biomarkers Prev 2008 Sep;17(9):2512-3

Department of Internal Medicine, Division of Hematology, Oncology and Blood & Marrow Transplantation, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674364PMC
September 2008

Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk.

Cancer Res 2008 Jun 10;68(12):4928-35. Epub 2008 Jun 10.

Division of Medical Oncology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652067PMC
June 2008

Analysis of variation in NF-kappaB genes and expression levels of NF-kappaB-regulated molecules.

BMC Proc 2007 18;1 Suppl 1:S126. Epub 2007 Dec 18.

Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street Southwest, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367504PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s126DOI Listing
December 2009

Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus.

Gastroenterology 2008 Apr 18;134(4):981-7. Epub 2008 Jan 18.

Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota.

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http://dx.doi.org/10.1053/j.gastro.2008.01.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323514PMC
April 2008

Mitochondrial genetic polymorphisms and pancreatic cancer risk.

Cancer Epidemiol Biomarkers Prev 2007 Jul;16(7):1455-9

Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, 200 First Street Southwest, Stabile 241, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0119DOI Listing
July 2007

Further validation of the FOUR score coma scale by intensive care nurses.

Mayo Clin Proc 2007 Apr;82(4):435-8

Department of Nursing, College of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002561961161070
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http://dx.doi.org/10.4065/82.4.435DOI Listing
April 2007

Design and analysis issues in cardiac arrhythmia trials: insights from the Detect Supraventricular Tachycardia Trial.

Clin Trials 2007 ;4(1):74-80

Department of Biostatistics, University of Washington, Seattle, Washington 98115, USA.

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http://journals.sagepub.com/doi/10.1177/1740774506075866
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http://dx.doi.org/10.1177/1740774506075866DOI Listing
June 2007

Hearing loss in rheumatoid arthritis.

Laryngoscope 2006 Nov;116(11):2044-9

Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1097/01.mlg.0000241365.54017.32DOI Listing
November 2006

Inherited variation in carcinogen-metabolizing enzymes and risk of colorectal polyps.

Carcinogenesis 2007 Feb 21;28(2):328-41. Epub 2006 Aug 21.

Cancer Prevention Program, Fred Hutchinson Cancer Research Center Seattle, WA, USA.

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http://dx.doi.org/10.1093/carcin/bgl135DOI Listing
February 2007

Association of family history of specific cancers with a younger age of onset of pancreatic adenocarcinoma.

Clin Gastroenterol Hepatol 2006 Sep 24;4(9):1143-7. Epub 2006 Jul 24.

Department of Oncology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1016/j.cgh.2006.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1899874PMC
September 2006

Validation of a new coma scale: The FOUR score.

Ann Neurol 2005 Oct;58(4):585-93

Division of Critical Care Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1002/ana.20611DOI Listing
October 2005

The presence of tandem endothelial nitric oxide synthase gene polymorphisms identifying brain aneurysms more prone to rupture.

J Neurosurg 2005 Mar;102(3):526-31

Department of Neurologic Surgery, Mayo Stroke Center and Microarray Shared Resource, Rochester, Minnesota 55905, USA.

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http://thejns.org/doi/10.3171/jns.2005.102.3.0526
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http://dx.doi.org/10.3171/jns.2005.102.3.0526DOI Listing
March 2005