William Muller

William Muller

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William Muller

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Varicella infection following vaccination in a pediatric kidney transplant recipient.

Pediatr Transplant 2020 Jun 18;24(4):e13667. Epub 2020 Feb 18.

Division of Infectious Diseases, Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, IL.

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http://dx.doi.org/10.1111/petr.13667DOI Listing
June 2020

Return of Individual Research Results: A Guide for Biomedical Researchers Utilizing Human Biospecimens.

Am J Pathol 2020 May 19;190(5):918-933. Epub 2020 Mar 19.

Veterans Health Administration, Washington, DC; University of Maryland School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.ajpath.2020.01.014DOI Listing
May 2020

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR.

Cell Rep 2020 Apr;31(4):107571

Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; Faculty of Medicine, McGill University, Montreal, QC H3A 1A3, Canada; Rosalind & Morris Goodman Cancer Centre, McGill University, Montreal, QC H3A 1A3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107571DOI Listing
April 2020

Endothelial Cell Calcium Signaling during Barrier Function and Inflammation.

Am J Pathol 2020 03 19;190(3):535-542. Epub 2019 Dec 19.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074364PMC
March 2020

Utility of metagenomic next generation sequencing (mNGS) of plasma for infectious pathogens.

Clin Infect Dis 2020 Mar 4. Epub 2020 Mar 4.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1093/cid/ciaa218DOI Listing
March 2020

Endothelial IQGAP1 regulates leukocyte transmigration by directing the LBRC to the site of diapedesis.

J Exp Med 2019 11 8;216(11):2582-2601. Epub 2019 Aug 8.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL

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http://dx.doi.org/10.1084/jem.20190008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829592PMC
November 2019

Risk factors for Clostridioides (Clostridium) difficile infection following solid organ transplantation in children.

Transpl Infect Dis 2019 Oct 5;21(5):e13149. Epub 2019 Aug 5.

Pediatric Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/tid.13149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800586PMC
October 2019

Reduction of Global H3K27me Enhances HER2/ErbB2 Targeted Therapy.

Cell Rep 2019 10;29(2):249-257.e8

Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montréal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montréal, QC H3A 1A3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.105DOI Listing
October 2019

Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer.

Cell Rep 2019 10;29(3):589-602.e6

Goodman Cancer Center, McGill University, Montreal, QC, Canada; Biochemistry Department, McGill University, Montreal, QC, Canada; Faculty of Medicine, McGill University, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.09.004DOI Listing
October 2019

Time-Variant SRC Kinase Activation Determines Endothelial Permeability Response.

Cell Chem Biol 2019 08 23;26(8):1081-1094.e6. Epub 2019 May 23.

Department of Pharmacology, The University of Illinois College of Medicine, 835 S. Wolcott Avenue, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697609PMC
August 2019

Lessons about early neurodevelopment in children exposed to ZIKV in utero.

Nat Med 2019 08;25(8):1192-1193

Departments of Pediatrics and Neurology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

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http://dx.doi.org/10.1038/s41591-019-0540-1DOI Listing
August 2019

Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience.

Open Forum Infect Dis 2019 Aug;6(8)

Division of Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1093/ofid/ofz327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677669PMC
August 2019

Cell-free DNA next-generation sequencing successfully detects infectious pathogens in pediatric oncology and hematopoietic stem cell transplant patients at risk for invasive fungal disease.

Pediatr Blood Cancer 2019 07 2;66(7):e27734. Epub 2019 Apr 2.

Division of Hematology, Oncology and Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.27734DOI Listing
July 2019

Laboratory Diagnosis of Neonatal Herpes Simplex Virus Infections.

J Clin Microbiol 2019 05 26;57(5). Epub 2019 Apr 26.

Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

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http://dx.doi.org/10.1128/JCM.01460-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498033PMC
May 2019

Outcomes of observation without empiric intravenous antibiotics in febrile, nonneutropenic pediatric oncology patients.

Pediatr Blood Cancer 2019 03 26;66(3):e27550. Epub 2018 Nov 26.

Division of Hematology, Oncology, & Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://doi.wiley.com/10.1002/pbc.27550
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http://dx.doi.org/10.1002/pbc.27550DOI Listing
March 2019

Vision screening in New Zealand: an audit of the B4 School Check.

N Z Med J 2019 03 8;132(1491):63-70. Epub 2019 Mar 8.

Ophthalmologist, Gisborne Hospital, Clinical Senior Lecturer, University of Otago, Gisborne.

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March 2019

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Cell Metab 2018 12 20;28(6):817-832.e8. Epub 2018 Sep 20.

Lady Davis Institute, SMBD JGH, McGill University, Montreal, QC H3A 1A3, Canada; Gerald Bronfman Department of Oncology, McGill University, Montreal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; Department of Experimental Medicine, McGill University, Montreal, QC H3A 1A3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252493PMC
December 2018

In vivo imaging reveals unique neutrophil transendothelial migration patterns in inflamed intestines.

Mucosal Immunol 2018 11 13;11(6):1571-1581. Epub 2018 Aug 13.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1038/s41385-018-0069-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279495PMC
November 2018

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

Cell Rep 2018 05;23(5):1476-1490

Montreal Clinical Research Institute (IRCM), Montréal, QC H2W 1R7, Canada; Molecular Biology Programs, Université de Montréal, Montréal, QC H3T 1J4, Canada; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada; Department of Anatomy and Cell Biology, McGill University, Montréal, QC H3A 0C7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.019DOI Listing
May 2018

In vivo evidence supporting a metastasis suppressor role for Stard13 (Dlc2) in ErbB2 (Neu) oncogene induced mouse mammary tumors.

Genes Chromosomes Cancer 2018 04 29;57(4):182-191. Epub 2017 Dec 29.

Research Institute of Oncology & Hematology, CancerCare Manitoba, Winnipeg, Manitoba, R3E 0V9, Canada.

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http://dx.doi.org/10.1002/gcc.22519DOI Listing
April 2018

Pediatric Considerations for Postexposure Human Immunodeficiency Virus Prophylaxis.

Infect Dis Clin North Am 2018 03;32(1):91-101

Division of Pediatric Infectious Diseases, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Avenue, Box 20, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.idc.2017.10.006DOI Listing
March 2018

Zika Virus: A Review for Pediatricians.

Pediatr Ann 2017 Nov;46(11):e428-e432

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http://dx.doi.org/10.3928/19382359-20171025-01DOI Listing
November 2017

MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury.

Circ Res 2017 Sep 29;121(8):930-940. Epub 2017 Aug 29.

From the Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL (M.D., X.Y.Y., S.D., S.Z., L.G., S.M., D.P., X.Z., D.C.Le., W.A.M., X.L., E.B.T.); Division of Molecular Medicine at Columbia University, New York (I.T.); and Department of Immunobiology, School of Medicine, Yale University (C.R.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.311327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623080PMC
September 2017

Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma.

Genes Dev 2017 08 8;31(15):1573-1587. Epub 2017 Sep 8.

Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.

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http://dx.doi.org/10.1101/gad.300566.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630022PMC
August 2017

Differential effect of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) on leukocyte infiltration during contact hypersensitivity responses.

PeerJ 2017 10;5:e3555. Epub 2017 Jul 10.

Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, United States of America.

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http://dx.doi.org/10.7717/peerj.3555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507171PMC
July 2017

Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.

Breast Cancer Res 2017 Jun 30;19(1):74. Epub 2017 Jun 30.

Department of Cancer Biology, Vanderbilt University School of Medicine, 2220 Pierce Avenue, Rm 749 Preston Research Building, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1186/s13058-017-0868-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493112PMC
June 2017

Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1.

Nat Commun 2017 05 5;8:15289. Epub 2017 May 5.

Department of Integrative Oncology, BC Cancer Research Centre, BC Cancer Agency, Vancouver, British Columbia, Canada V5Z 1L3.

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http://dx.doi.org/10.1038/ncomms15289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424153PMC
May 2017

LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis.

Nat Commun 2017 04 24;8:15059. Epub 2017 Apr 24.

Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada H3A 1A3.

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http://dx.doi.org/10.1038/ncomms15059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413977PMC
April 2017

Roles of transient receptor potential channels in regulation of vascular and epithelial barriers.

Tissue Barriers 2017 04 17;5(2):e1331722. Epub 2017 May 17.

b Northwestern University , Feinberg School of Medicine , Chicago , IL , USA.

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http://dx.doi.org/10.1080/21688370.2017.1331722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501133PMC
April 2017

Mapping sites of herpes simplex virus type 1 glycoprotein D that permit insertions and impact gD and gB receptors usage.

Sci Rep 2017 03 3;7:43712. Epub 2017 Mar 3.

Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://www.nature.com/articles/srep43712
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http://dx.doi.org/10.1038/srep43712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334651PMC
March 2017

Treatment of perinatal viral infections to improve neurologic outcomes.

Authors:
William J Muller

Pediatr Res 2017 01 27;81(1-2):162-169. Epub 2016 Sep 27.

Department of Pediatrics, Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1038/pr.2016.191DOI Listing
January 2017

Preliminary Results From the US Zika Pregnancy Registry: Untangling Risks for Congenital Anomalies.

JAMA 2017 01;317(1):35-36

Department of Obstetrics-Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1001/jama.2016.18632DOI Listing
January 2017

β-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model.

Proc Natl Acad Sci U S A 2017 01 17;114(5):E707-E716. Epub 2017 Jan 17.

Goodman Cancer Center, McGill University, Montreal, QC H3A 1A3, Canada;

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http://dx.doi.org/10.1073/pnas.1610383114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293039PMC
January 2017

The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.

Breast Cancer Res 2016 12 20;18(1):131. Epub 2016 Dec 20.

Department of Pathology, MS 8401, University of Colorado Anschutz Medical Campus, 12801 East 17th Avenue, Box 8104, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1186/s13058-016-0795-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168867PMC
December 2016

4D intravital microscopy uncovers critical strain differences for the roles of PECAM and CD99 in leukocyte diapedesis.

Am J Physiol Heart Circ Physiol 2016 09 15;311(3):H621-32. Epub 2016 Jul 15.

Department of Pathology, Feinberg School of Medicine, Chicago, Illinois

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http://dx.doi.org/10.1152/ajpheart.00289.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142183PMC
September 2016

Transendothelial migration: unifying principles from the endothelial perspective.

Authors:
William A Muller

Immunol Rev 2016 09;273(1):61-75

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1111/imr.12443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5090979PMC
September 2016

How monocytes guard the glomerulus.

Authors:
William A Muller

Proc Natl Acad Sci U S A 2016 09 1;113(38):10453-5. Epub 2016 Sep 1.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035906PMC
http://dx.doi.org/10.1073/pnas.1612425113DOI Listing
September 2016

Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.

Cancer Res 2016 08 25;76(16):4752-64. Epub 2016 Apr 25.

Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee. The Vanderbilt-Ingram Cancer Center at Vanderbilt University, Vanderbilt University, Nashville, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758362PMC
August 2016

Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation.

Endocrinology 2016 06 27;157(6):2204-16. Epub 2016 Apr 27.

Department of Medicine (J.L., A.-L.L., B.O., I.F., A.C., R.K.), McGill University Health Centre and Goodman Cancer Research Centre (W.M.), McGill University, Montréal, Québec, Canada H3A 1A1; United States Department of Agriculture (Agricultural Research Service) National Animal Disease Center (T.A.R.), Ames, Iowa 50010; and Genetics Unit (R.S.-A.), Shriners Hospital for Children, Montréal, Québec, Canada H3G 1A6.

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http://dx.doi.org/10.1210/en.2015-1824DOI Listing
June 2016

Targeted Recycling of the Lateral Border Recycling Compartment Precedes Adherens Junction Dissociation during Transendothelial Migration.

Am J Pathol 2016 05 8;186(5):1387-402. Epub 2016 Mar 8.

Department of Pathology, The Feinberg School of Medicine at Northwestern University, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861767PMC
May 2016

A Unique Role for Endothelial Cell Kinesin Light Chain 1, Variant 1 in Leukocyte Transendothelial Migration.

Am J Pathol 2016 05 17;186(5):1375-86. Epub 2016 Mar 17.

Department of Pathology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2016.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861765PMC
May 2016

The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis.

mBio 2016 Apr 12;7(2):e00437-16. Epub 2016 Apr 12.

Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

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http://dx.doi.org/10.1128/mBio.00437-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959527PMC
April 2016

Localized signals that regulate transendothelial migration.

Authors:
William A Muller

Curr Opin Immunol 2016 Feb 14;38:24-9. Epub 2015 Nov 14.

Department of Pathology, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL 60201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2015.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715928PMC
February 2016

Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer.

Dis Model Mech 2016 Feb 31;9(2):131-40. Epub 2015 Dec 31.

Edinburgh Cancer Research UK Centre, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK

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http://dx.doi.org/10.1242/dmm.023143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770148PMC
February 2016

CD99-like 2 (CD99L2)-deficient mice are defective in the acute inflammatory response.

Exp Mol Pathol 2015 Dec 29;99(3):455-9. Epub 2015 Aug 29.

Department of Pathology,Northwestern University Feinberg School of Medicine,303 East Chicago Avenue,Chicago,IL 60611, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yexmp.2015.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679605PMC
December 2015

Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition.

Mol Cell Biol 2015 Dec 21;35(23):4069-82. Epub 2015 Sep 21.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec, Canada Department of Medicine, McGill University, Montréal, Québec, Canada Department of Medicine, University of Montréal, Montréal, Québec, Canada

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http://dx.doi.org/10.1128/MCB.00741-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628068PMC
December 2015

HSV targeting of the host phosphatase PP1α is required for disseminated disease in the neonate and contributes to pathogenesis in the brain.

Proc Natl Acad Sci U S A 2015 Dec 30;112(50):E6937-44. Epub 2015 Nov 30.

Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611;

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http://dx.doi.org/10.1073/pnas.1513045112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687582PMC
December 2015

TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response.

J Exp Med 2015 Oct 21;212(11):1883-99. Epub 2015 Sep 21.

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611

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http://dx.doi.org/10.1084/jem.20150353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612081PMC
October 2015

The regulation of transendothelial migration: new knowledge and new questions.

Authors:
William A Muller

Cardiovasc Res 2015 Aug 17;107(3):310-20. Epub 2015 May 17.

Department of Pathology, Northwestern University Feinberg School of Medicine, Ward Building 3-140, 303 East Chicago Avenue, Chicago, IL 60611, USA

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http://dx.doi.org/10.1093/cvr/cvv145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592322PMC
August 2015

Monocytes from HIV-infected individuals show impaired cholesterol efflux and increased foam cell formation after transendothelial migration.

AIDS 2015 Jul;29(12):1445-57

aCentre for Biomedical Research, Burnet Institute bDepartment of Infectious Diseases, Monash University cSchool of Applied Sciences, RMIT University dMonash Micro Imaging, Monash University eDepartment of Microbiology and Immunology, Melbourne University, Melbourne, Victoria, Australia fFeinberg School of Medicine, Northwestern University, Chicago, Illinois, USA gDepartment of Immunology, Monash University, Melbourne, Victoria, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086669PMC
http://dx.doi.org/10.1097/QAD.0000000000000739DOI Listing
July 2015

Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.

J Exp Med 2015 Jun 22;212(7):1021-41. Epub 2015 Jun 22.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60208

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http://dx.doi.org/10.1084/jem.20150354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493416PMC
June 2015

Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer.

Cancer Prev Res (Phila) 2015 Feb 2;8(2):120-8. Epub 2014 Dec 2.

Department of Medicine, McGill University Health Centre, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0110DOI Listing
February 2015

Differential reliance on autophagy for protection from HSV encephalitis between newborns and adults.

PLoS Pathog 2015 Jan 8;11(1):e1004580. Epub 2015 Jan 8.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287605PMC
January 2015

Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.

Breast Cancer Res 2015 Jan 16;17. Epub 2015 Jan 16.

Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.

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http://dx.doi.org/10.1186/s13058-014-0513-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355979PMC
January 2015

Early viral suppression improves neurocognitive outcomes in HIV-infected children.

AIDS 2015 Jan;29(3):295-304

Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Washington and Seattle Children's Hospital, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332557PMC
January 2015

Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV.

Pediatr Res 2014 Dec 8;76(6):528-34. Epub 2014 Sep 8.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1038/pr.2014.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233006PMC
December 2014

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction.

Mol Cell Biol 2014 Dec 22;34(23):4232-43. Epub 2014 Sep 22.

Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada Department of Biochemistry, McGill University, Montréal, Quebec, Canada Department of Medicine and Oncology, McGill University, Montréal, Quebec, Canada

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http://dx.doi.org/10.1128/MCB.00895-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248744PMC
December 2014

Herpesvirus entry mediator (HVEM) attenuates signals mediated by the lymphotoxin β receptor (LTβR) in human cells stimulated by the shared ligand LIGHT.

Mol Immunol 2014 Nov 28;62(1):96-103. Epub 2014 Jun 28.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Northwestern University, 310 East Superior Street, Morton 4-685, Chicago, IL 60611 USA. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2014.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157106PMC
November 2014

Neurologic disease in HIV-infected children and the impact of combination antiretroviral therapy.

Rev Med Virol 2014 Sep 8;24(5):316-31. Epub 2014 May 8.

Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1002/rmv.1793DOI Listing
September 2014

Isolation of the lateral border recycling compartment using a diaminobenzidine-induced density shift.

Traffic 2014 Sep 1;15(9):1016-29. Epub 2014 Jul 1.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1111/tra.12184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140980PMC
September 2014

Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier.

J Immunol 2014 Sep 25;193(5):2427-37. Epub 2014 Jul 25.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611;

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http://dx.doi.org/10.4049/jimmunol.1400700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138548PMC
September 2014

Microhemorrhage is an early event in the pulmonary fibrotic disease of PECAM-1 deficient FVB/n mice.

Exp Mol Pathol 2014 Aug 24;97(1):128-36. Epub 2014 Jun 24.

Department of Microbiology, Immunology, and Pathology, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523, United States.

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http://dx.doi.org/10.1016/j.yexmp.2014.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414406PMC
August 2014

Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.

Cancer Res 2014 Aug 30;74(16):4270-81. Epub 2014 Jun 30.

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana. Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-2817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134725PMC
August 2014

Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model.

BMC Cancer 2014 Jul 11;14:509. Epub 2014 Jul 11.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, Priority Research Centre in Cancer, University of Newcastle, Newcastle, NSW, Australia.

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http://link.springer.com/content/pdf/10.1186%2F1471-2407-14-
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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-14-509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226978PMC
July 2014

Mammary tumour development is dose-dependently inhibited by n-3 polyunsaturated fatty acids in the MMTV-neu(ndl)-YD5 transgenic mouse model.

Lipids Health Dis 2014 Jun 11;13:96. Epub 2014 Jun 11.

Department of Human Health and Nutritional Sciences, University of Guelph, Animal Science/Nutrition Building, Room 342, 491 Gordon Street, N1G 2W1 Guelph, ON, Canada.

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http://dx.doi.org/10.1186/1476-511X-13-96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064525PMC
June 2014

Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors.

Cell Res 2014 May 28;24(5):542-59. Epub 2014 Mar 28.

1] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA [2] Cancer Biology Program, Graduate School of Biomedical Sciences-Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/cr.2014.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011340PMC
May 2014

How endothelial cells regulate transmigration of leukocytes in the inflammatory response.

Authors:
William A Muller

Am J Pathol 2014 Apr;184(4):886-96

Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2013.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969991PMC
April 2014

Commentary on "Medical and Surgical Management of a Descending Aorta Penetrating Atherosclerotic Ulcer and Associated Ascending Intramural Hematoma" by Henn, M.C. et al.

Aorta (Stamford) 2014 Apr 1;2(2):82-3. Epub 2014 Apr 1.

Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia.

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http://dx.doi.org/10.12945/j.aorta.2014.14-999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682760PMC
April 2014