William Marzluff

William Marzluff

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William Marzluff

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Determining degradation intermediates and the pathway of 3' to 5' degradation of histone mRNA using high-throughput sequencing.

Methods 2019 02 5;155:104-115. Epub 2018 Nov 5.

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2018.11.001DOI Listing
February 2019

Tissue-Dependent Expression and Translation of Circular RNAs with Recombinant AAV Vectors In Vivo.

Mol Ther Nucleic Acids 2018 Dec 18;13:89-98. Epub 2018 Aug 18.

Curriculum in Genetics and Molecular Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7352, USA; Gene Therapy Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7352, USA; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7352, USA; Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7352, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S21622531183022
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http://dx.doi.org/10.1016/j.omtn.2018.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154398PMC
December 2018

Role of oligouridylation in normal metabolism and regulated degradation of mammalian histone mRNAs.

Philos Trans R Soc Lond B Biol Sci 2018 11 5;373(1762). Epub 2018 Nov 5.

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA

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http://rstb.royalsocietypublishing.org/lookup/doi/10.1098/rs
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http://dx.doi.org/10.1098/rstb.2018.0170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232589PMC
November 2018

Protein composition of catalytically active U7-dependent processing complexes assembled on histone pre-mRNA containing biotin and a photo-cleavable linker.

Nucleic Acids Res 2018 05;46(9):4752-4770

Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1093/nar/gky133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961079PMC
May 2018

Synthetic mRNA with Superior Properties that Mimics the Intracellular Fates of Natural Histone mRNA.

Methods Mol Biol 2016 ;1428:93-114

Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130-3932, USA.

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http://dx.doi.org/10.1007/978-1-4939-3625-0_6DOI Listing
December 2017

Birth and Death of Histone mRNAs.

Trends Genet 2017 10 31;33(10):745-759. Epub 2017 Aug 31.

Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01689525173013
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http://dx.doi.org/10.1016/j.tig.2017.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645032PMC
October 2017

Histone locus regulation by the dosage compensation adaptor protein CLAMP.

Genes Dev 2017 07 24;31(14):1494-1508. Epub 2017 Aug 24.

Department of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, Rhode Island 02912, USA.

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http://dx.doi.org/10.1101/gad.300855.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588930PMC
July 2017

Coordinating cell cycle-regulated histone gene expression through assembly and function of the Histone Locus Body.

RNA Biol 2017 06 6;14(6):726-738. Epub 2017 Jan 6.

a Department of Biology , University of North Carolina , Chapel Hill , NC , USA.

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http://dx.doi.org/10.1080/15476286.2016.1265198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519241PMC
June 2017

U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem-loop binding protein.

RNA 2017 06 13;23(6):938-951. Epub 2017 Mar 13.

Integrative Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1261/rna.060806.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435866PMC
June 2017

Inducing circular RNA formation using the CRISPR endoribonuclease Csy4.

RNA 2017 05 21;23(5):619-627. Epub 2017 Feb 21.

Gene Therapy Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1261/rna.056838.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393173PMC
May 2017

TUT7 catalyzes the uridylation of the 3' end for rapid degradation of histone mRNA.

RNA 2016 11 8;22(11):1673-1688. Epub 2016 Sep 8.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1261/rna.058107.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066620PMC
November 2016

DDB1 and CUL4 associated factor 11 (DCAF11) mediates degradation of Stem-loop binding protein at the end of S phase.

Cell Cycle 2016 Aug 2;15(15):1986-96. Epub 2016 Jun 2.

a Department of Genetics and Bioengineering , Fatih University , Istanbul , Turkey.

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http://dx.doi.org/10.1080/15384101.2016.1191708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968976PMC
August 2016

Concentrating pre-mRNA processing factors in the histone locus body facilitates efficient histone mRNA biogenesis.

J Cell Biol 2016 06 30;213(5):557-70. Epub 2016 May 30.

Department of Biology, University of North Carolina, Chapel Hill, NC 27599 Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599 Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC 27599 Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599 Department of Genetics, University of North Carolina, Chapel Hill, NC 27599

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http://dx.doi.org/10.1083/jcb.201504043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896052PMC
June 2016

Mapping the Interaction Network of Key Proteins Involved in Histone mRNA Generation: A Hydrogen/Deuterium Exchange Study.

J Mol Biol 2016 Mar 6;428(6):1180-1196. Epub 2016 Feb 6.

Department of Biophysics, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02-106 Warsaw, Poland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222836160008
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http://dx.doi.org/10.1016/j.jmb.2016.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847949PMC
March 2016

Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4.

RNA 2015 Nov 9;21(11):1921-30. Epub 2015 Sep 9.

Gene Therapy Center, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA Department of Genetics, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://rnajournal.cshlp.org/lookup/doi/10.1261/rna.051227.11
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http://dx.doi.org/10.1261/rna.051227.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604432PMC
November 2015

A multiprotein occupancy map of the mRNP on the 3' end of histone mRNAs.

RNA 2015 Nov 16;21(11):1943-65. Epub 2015 Sep 16.

Department of Genetics, Dartmouth Geisel School of Medicine, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1261/rna.053389.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4604434PMC
November 2015

EnD-Seq and AppEnD: sequencing 3' ends to identify nontemplated tails and degradation intermediates.

RNA 2015 Jul 26;21(7):1375-89. Epub 2015 May 26.

Curriculum in Bioinformatics and Computational Biology, Department of Biochemistry and Biophysics, Department of Biology, Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599, USA

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http://dx.doi.org/10.1261/rna.048785.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478355PMC
July 2015

Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body.

Mol Biol Cell 2015 Apr 18;26(8):1559-74. Epub 2015 Feb 18.

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599 Department of Biology, University of North Carolina, Chapel Hill, NC 27599 Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599 Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC 27599 Department of Genetics, University of North Carolina, Chapel Hill, NC 27599

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http://dx.doi.org/10.1091/mbc.E14-10-1445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395134PMC
April 2015

Twenty years of RNA: reflections on post-transcriptional regulation.

RNA 2015 Apr;21(4):687-9

Department of Biochemistry and Biophysics, Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599, USA

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http://dx.doi.org/10.1261/rna.050997.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371334PMC
April 2015

A conserved interaction that is essential for the biogenesis of histone locus bodies.

J Biol Chem 2014 Dec 22;289(49):33767-82. Epub 2014 Oct 22.

From the Department of Biochemistry and Biophysics, Integrative Program in Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 and

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http://dx.doi.org/10.1074/jbc.M114.616466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256312PMC
December 2014

Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation.

Proc Natl Acad Sci U S A 2014 Jul 7;111(29):E2937-46. Epub 2014 Jul 7.

Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709;

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http://dx.doi.org/10.1073/pnas.1406381111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115514PMC
July 2014

Genome stress response in early development.

Dev Cell 2014 May;29(4):375-6

Departments of Biology and Genetics, University of North Carolina, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA; Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107455PMC
May 2014

Translation regulation and proteasome mediated degradation cooperate to keep stem-loop binding protein low in G1-phase.

J Cell Biochem 2014 Mar;115(3):523-30

Department of Genetics and Bioengineering, Fatih University Istanbul, Istanbul, Turkey; Bionanotechnology Center, Fatih University Istanbul, Istanbul, Turkey.

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http://dx.doi.org/10.1002/jcb.24686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391495PMC
March 2014

Deep sequencing shows multiple oligouridylations are required for 3' to 5' degradation of histone mRNAs on polyribosomes.

Mol Cell 2014 Mar;53(6):1020-30

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA; Integrative Program for Biological and Genome Sciences, University of North Carolina, Chapel Hill, NC 27599, USA; Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403670PMC
March 2014

Cell cycle-regulated protein abundance changes in synchronously proliferating HeLa cells include regulation of pre-mRNA splicing proteins.

PLoS One 2013 8;8(3):e58456. Epub 2013 Mar 8.

Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058456PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592840PMC
September 2013

Structural and biochemical studies of SLIP1-SLBP identify DBP5 and eIF3g as SLIP1-binding proteins.

Nucleic Acids Res 2013 Sep 26;41(16):7960-71. Epub 2013 Jun 26.

Structural Cell Biology Department, Max Planck Institute of Biochemistry, Munich, D-82152 Germany and Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1093/nar/gkt558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763545PMC
September 2013

Circular RNAs are abundant, conserved, and associated with ALU repeats.

RNA 2013 Feb 18;19(2):141-57. Epub 2012 Dec 18.

Department of Genetics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7295, USA.

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http://dx.doi.org/10.1261/rna.035667.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543092PMC
February 2013

A complex containing the CPSF73 endonuclease and other polyadenylation factors associates with U7 snRNP and is recruited to histone pre-mRNA for 3'-end processing.

Mol Cell Biol 2013 Jan 15;33(1):28-37. Epub 2012 Oct 15.

Department of Biochemistry and Biophysics, Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1128/MCB.00653-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536302PMC
January 2013

mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end.

RNA 2013 Jan 27;19(1):1-16. Epub 2012 Nov 27.

Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, Louisiana 71130-3932, USA.

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http://dx.doi.org/10.1261/rna.034470.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527721PMC
January 2013

Rare codons regulate KRas oncogenesis.

Curr Biol 2013 Jan 13;23(1):70-5. Epub 2012 Dec 13.

Department of Pharmacology & Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09609822120137
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http://dx.doi.org/10.1016/j.cub.2012.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567844PMC
January 2013

Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex.

Science 2013 Jan;339(6117):318-21

Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1126/science.1228705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552377PMC
January 2013

An RNAi screen identifies additional members of the Drosophila Integrator complex and a requirement for cyclin C/Cdk8 in snRNA 3'-end formation.

RNA 2012 Dec 24;18(12):2148-56. Epub 2012 Oct 24.

Department of Biochemistry and Molecular Biology, The University of Texas Medical School at Houston, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1261/rna.035725.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504667PMC
December 2012

Systematic reconstruction of RNA functional motifs with high-throughput microfluidics.

Nat Methods 2012 Dec 11;9(12):1192-4. Epub 2012 Nov 11.

Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1038/nmeth.2225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863600PMC
December 2012

Novel 3' ends that support translation.

Genes Dev 2012 Nov;26(22):2457-60

Program in Molecular Biology, Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1101/gad.207233.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3505814PMC
November 2012

Histones: sequestered by Jabba in fatty storehouse.

Curr Biol 2012 Nov;22(22):R951-3

Department of Biochemistry, University of North Carolina at Chapel Hill School of Medicine, 208 Fordham Hall, Campus Box # 7100, Chapel Hill, NC 27599, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09609822120115
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http://dx.doi.org/10.1016/j.cub.2012.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711088PMC
November 2012

Coordinate inactivation of zinc finger transcription factors at mitosis.

Cell Cycle 2011 Dec 1;10(23):3994. Epub 2011 Dec 1.

University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.4161/cc.10.23.18235DOI Listing
December 2011

Interaction between FLASH and Lsm11 is essential for histone pre-mRNA processing in vivo in Drosophila.

RNA 2011 Jun 27;17(6):1132-47. Epub 2011 Apr 27.

Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1261/rna.2566811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096045PMC
June 2011

FLASH is required for the endonucleolytic cleavage of histone pre-mRNAs but is dispensable for the 5' exonucleolytic degradation of the downstream cleavage product.

Mol Cell Biol 2011 Apr 18;31(7):1492-502. Epub 2011 Jan 18.

Department of Biochemistry and Biophysics, Program in Molecular Biology and Biotechnology, CB 3280, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1128/MCB.00979-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135297PMC
April 2011

Mutation of the 5'-untranslated region stem-loop structure inhibits α1(I) collagen expression in vivo.

J Biol Chem 2011 Mar 30;286(10):8609-19. Epub 2010 Dec 30.

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599-7080, USA.

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http://dx.doi.org/10.1074/jbc.M110.189118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048743PMC
March 2011

A subset of Drosophila integrator proteins is essential for efficient U7 snRNA and spliceosomal snRNA 3'-end formation.

Mol Cell Biol 2011 Jan 15;31(2):328-41. Epub 2010 Nov 15.

Department of Biochemistry and Molecular Biology, The University of Texas Medical School, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1128/MCB.00943-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019983PMC
January 2011

More than one way to make a tail.

EMBO J 2010 Dec;29(24):4066-7

Program in Molecular Biology and Biotechnology, Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/emboj.2010.306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018801PMC
December 2010

Coordinate regulation of histone mRNA metabolism and DNA replication: cyclin A/cdk1 is involved in inactivation of histone mRNA metabolism and DNA replication at the end of S phase.

Cell Cycle 2010 Oct 9;9(19):3857-63. Epub 2010 Oct 9.

Department of Biology and Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047749PMC
http://dx.doi.org/10.4161/cc.9.19.13300DOI Listing
October 2010

Terminating histone synthesis to preserve centromere integrity.

Dev Cell 2010 Mar;18(3):335-6

The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3280, USA.

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http://dx.doi.org/10.1016/j.devcel.2010.03.004DOI Listing
March 2010

FLASH, a proapoptotic protein involved in activation of caspase-8, is essential for 3' end processing of histone pre-mRNAs.

Mol Cell 2009 Oct;36(2):267-78

Department of Biochemistry and Biophysics and Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.molcel.2009.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819824PMC
October 2009

Crystal structure of the HEAT domain from the Pre-mRNA processing factor Symplekin.

J Mol Biol 2009 Sep 1;392(1):115-28. Epub 2009 Jul 1.

Department of Chemistry, University of North Carolina at Chapel Hill, 27599, USA.

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http://dx.doi.org/10.1016/j.jmb.2009.06.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748850PMC
September 2009

Three proteins of the U7-specific Sm ring function as the molecular ruler to determine the site of 3'-end processing in mammalian histone pre-mRNA.

Mol Cell Biol 2009 Aug 26;29(15):4045-56. Epub 2009 May 26.

Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1128/MCB.00296-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715809PMC
August 2009

A new way to initiate mRNA degradation.

Authors:
William Marzluff

Nat Struct Mol Biol 2009 Jun;16(6):613-4

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http://dx.doi.org/10.1038/nsmb0609-613DOI Listing
June 2009

Knockdown of SLBP results in nuclear retention of histone mRNA.

RNA 2009 Mar 20;15(3):459-72. Epub 2009 Jan 20.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://rnajournal.cshlp.org/cgi/doi/10.1261/rna.1205409
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http://dx.doi.org/10.1261/rna.1205409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657014PMC
March 2009

Chapter 2. Cell-cycle regulation of histone mRNA degradation in Mammalian cells: role of translation and oligouridylation.

Methods Enzymol 2008 ;449:23-45

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1016/S0076-6879(08)02402-6DOI Listing
March 2009

Studies of the 5' exonuclease and endonuclease activities of CPSF-73 in histone pre-mRNA processing.

Mol Cell Biol 2009 Jan 27;29(1):31-42. Epub 2008 Oct 27.

Program in Molecular Biology and Biotechnology, CB #3280, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1128/MCB.00776-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612496PMC
January 2009

Cyclin E in centrosome duplication and reduplication in sea urchin zygotes.

J Cell Physiol 2008 Dec;217(3):626-31

Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1002/jcp.21531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950072PMC
December 2008

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail.

Nat Rev Genet 2008 Nov;9(11):843-54

Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1038/nrg2438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715827PMC
November 2008

Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells.

Proc Natl Acad Sci U S A 2008 Nov 28;105(44):16964-9. Epub 2008 Oct 28.

Center for Stem Cell Biology and Regenerative Medicine, Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0809273105
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http://dx.doi.org/10.1073/pnas.0809273105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579361PMC
November 2008

Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase.

Mol Cell Biol 2008 Jul 19;28(14):4469-79. Epub 2008 May 19.

Department of Biology, Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1128/MCB.01416-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447125PMC
July 2008

SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.

Mol Cell Biol 2008 Feb 19;28(3):1182-94. Epub 2007 Nov 19.

Program in Molecular Biology and Biotechnology, CB #7100, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1128/MCB.01500-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2223387PMC
February 2008

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.

Genes Dev 2008 Jan;22(1):50-65

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1101/gad.1622708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2151014PMC
January 2008

U2 snRNP: not just for poly(A) mRNAs.

Mol Cell 2007 Nov;28(3):353-4

Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.molcel.2007.10.015DOI Listing
November 2007

A genome-wide RNA interference screen reveals that variant histones are necessary for replication-dependent histone pre-mRNA processing.

Mol Cell 2007 Nov;28(4):692-9

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.molcel.2007.10.009DOI Listing
November 2007

Developmental and cell cycle regulation of the Drosophila histone locus body.

Mol Biol Cell 2007 Jul 18;18(7):2491-502. Epub 2007 Apr 18.

Department of Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1091/mbc.e06-11-1033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1924828PMC
July 2007

Formation of the 3' end of histone mRNA: getting closer to the end.

Gene 2007 Jul 4;396(2):373-90. Epub 2007 May 4.

Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.gene.2007.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2888136PMC
July 2007

Cyclin E/Cdk2 is required for sperm maturation, but not DNA replication, in early sea urchin embryos.

Genesis 2007 May;45(5):282-91

Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1002/dvg.20291DOI Listing
May 2007

The sea urchin histone gene complement.

Dev Biol 2006 Dec 1;300(1):308-20. Epub 2006 Sep 1.

Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.ydbio.2006.08.067DOI Listing
December 2006

The genomic repertoire for cell cycle control and DNA metabolism in S. purpuratus.

Dev Biol 2006 Dec 14;300(1):238-51. Epub 2006 Sep 14.

Observatoire Océanologique de Banyuls-Laboratoire Arago, CNRS-UMR7628/UPMC, 66650 Banyuls-sur-Mer, France.

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http://dx.doi.org/10.1016/j.ydbio.2006.09.012DOI Listing
December 2006

Genetic and biochemical characterization of Drosophila Snipper: A promiscuous member of the metazoan 3'hExo/ERI-1 family of 3' to 5' exonucleases.

RNA 2006 Dec 24;12(12):2103-17. Epub 2006 Oct 24.

Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1261/rna.186706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1664731PMC
December 2006

The genome of the sea urchin Strongylocentrotus purpuratus.

Authors:
Erica Sodergren George M Weinstock Eric H Davidson R Andrew Cameron Richard A Gibbs Robert C Angerer Lynne M Angerer Maria Ina Arnone David R Burgess Robert D Burke James A Coffman Michael Dean Maurice R Elphick Charles A Ettensohn Kathy R Foltz Amro Hamdoun Richard O Hynes William H Klein William Marzluff David R McClay Robert L Morris Arcady Mushegian Jonathan P Rast L Courtney Smith Michael C Thorndyke Victor D Vacquier Gary M Wessel Greg Wray Lan Zhang Christine G Elsik Olga Ermolaeva Wratko Hlavina Gretchen Hofmann Paul Kitts Melissa J Landrum Aaron J Mackey Donna Maglott Georgia Panopoulou Albert J Poustka Kim Pruitt Victor Sapojnikov Xingzhi Song Alexandre Souvorov Victor Solovyev Zheng Wei Charles A Whittaker Kim Worley K James Durbin Yufeng Shen Olivier Fedrigo David Garfield Ralph Haygood Alexander Primus Rahul Satija Tonya Severson Manuel L Gonzalez-Garay Andrew R Jackson Aleksandar Milosavljevic Mark Tong Christopher E Killian Brian T Livingston Fred H Wilt Nikki Adams Robert Bellé Seth Carbonneau Rocky Cheung Patrick Cormier Bertrand Cosson Jenifer Croce Antonio Fernandez-Guerra Anne-Marie Genevière Manisha Goel Hemant Kelkar Julia Morales Odile Mulner-Lorillon Anthony J Robertson Jared V Goldstone Bryan Cole David Epel Bert Gold Mark E Hahn Meredith Howard-Ashby Mark Scally John J Stegeman Erin L Allgood Jonah Cool Kyle M Judkins Shawn S McCafferty Ashlan M Musante Robert A Obar Amanda P Rawson Blair J Rossetti Ian R Gibbons Matthew P Hoffman Andrew Leone Sorin Istrail Stefan C Materna Manoj P Samanta Viktor Stolc Waraporn Tongprasit Qiang Tu Karl-Frederik Bergeron Bruce P Brandhorst James Whittle Kevin Berney David J Bottjer Cristina Calestani Kevin Peterson Elly Chow Qiu Autumn Yuan Eran Elhaik Dan Graur Justin T Reese Ian Bosdet Shin Heesun Marco A Marra Jacqueline Schein Michele K Anderson Virginia Brockton Katherine M Buckley Avis H Cohen Sebastian D Fugmann Taku Hibino Mariano Loza-Coll Audrey J Majeske Cynthia Messier Sham V Nair Zeev Pancer David P Terwilliger Cavit Agca Enrique Arboleda Nansheng Chen Allison M Churcher F Hallböök Glen W Humphrey Mohammed M Idris Takae Kiyama Shuguang Liang Dan Mellott Xiuqian Mu Greg Murray Robert P Olinski Florian Raible Matthew Rowe John S Taylor Kristin Tessmar-Raible D Wang Karen H Wilson Shunsuke Yaguchi Terry Gaasterland Blanca E Galindo Herath J Gunaratne Celina Juliano Masashi Kinukawa Gary W Moy Anna T Neill Mamoru Nomura Michael Raisch Anna Reade Michelle M Roux Jia L Song Yi-Hsien Su Ian K Townley Ekaterina Voronina Julian L Wong Gabriele Amore Margherita Branno Euan R Brown Vincenzo Cavalieri Véronique Duboc Louise Duloquin Constantin Flytzanis Christian Gache François Lapraz Thierry Lepage Annamaria Locascio Pedro Martinez Giorgio Matassi Valeria Matranga Ryan Range Francesca Rizzo Eric Röttinger Wendy Beane Cynthia Bradham Christine Byrum Tom Glenn Sofia Hussain Gerard Manning Esther Miranda Rebecca Thomason Katherine Walton Athula Wikramanayke Shu-Yu Wu Ronghui Xu C Titus Brown Lili Chen Rachel F Gray Pei Yun Lee Jongmin Nam Paola Oliveri Joel Smith Donna Muzny Stephanie Bell Joseph Chacko Andrew Cree Stacey Curry Clay Davis Huyen Dinh Shannon Dugan-Rocha Jerry Fowler Rachel Gill Cerrissa Hamilton Judith Hernandez Sandra Hines Jennifer Hume Laronda Jackson Angela Jolivet Christie Kovar Sandra Lee Lora Lewis George Miner Margaret Morgan Lynne V Nazareth Geoffrey Okwuonu David Parker Ling-Ling Pu Rachel Thorn Rita Wright

Science 2006 Nov;314(5801):941-52

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http://dx.doi.org/10.1126/science.1133609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159423PMC
November 2006

A Golgi-localized hexose transporter is involved in heterotrimeric G protein-mediated early development in Arabidopsis.

Mol Biol Cell 2006 Oct 19;17(10):4257-69. Epub 2006 Jul 19.

Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3280, USA.

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http://dx.doi.org/10.1091/mbc.e06-01-0046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635373PMC
October 2006

Characterization of 3'hExo, a 3' exonuclease specifically interacting with the 3' end of histone mRNA.

J Biol Chem 2006 Oct 15;281(41):30447-54. Epub 2006 Aug 15.

Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1074/jbc.M602947200DOI Listing
October 2006

Genome-wide analysis of mRNAs bound to the histone stem-loop binding protein.

RNA 2006 Oct 24;12(10):1853-67. Epub 2006 Aug 24.

Department of Genetics, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.

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http://dx.doi.org/10.1261/rna.76006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1581977PMC
October 2006

ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase.

Mol Cell Biol 2006 Sep;26(17):6702-12

Program in Molecular Biology and Biotechnology, CB #7100, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1128/MCB.00391-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1592837PMC
September 2006

Conserved zinc fingers mediate multiple functions of ZFP100, a U7snRNP associated protein.

RNA 2006 Jul 18;12(7):1206-18. Epub 2006 May 18.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://www.rnajournal.org/cgi/doi/10.1261/rna.2606
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http://dx.doi.org/10.1261/rna.2606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1484431PMC
July 2006

Nuclear autoantigenic sperm protein (NASP), a linker histone chaperone that is required for cell proliferation.

J Biol Chem 2006 Jul 25;281(30):21526-34. Epub 2006 May 25.

Department of Cell and Developmental Biology, University of North Carolina, Chapel Hill, 27599, USA.

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http://dx.doi.org/10.1074/jbc.M603816200DOI Listing
July 2006

Phosphatase-directed phosphorylation-site determination: a synthesis of methods for the detection and identification of phosphopeptides.

J Proteome Res 2005 Sep-Oct;4(5):1628-35

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1021/pr050129dDOI Listing
January 2006

Differences and similarities between Drosophila and mammalian 3' end processing of histone pre-mRNAs.

RNA 2005 Dec 26;11(12):1835-47. Epub 2005 Oct 26.

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1261/rna.2179305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370872PMC
December 2005

The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processing.

Cell 2005 Oct;123(1):37-48

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.cell.2005.08.002DOI Listing
October 2005

Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.

Nat Struct Mol Biol 2005 Sep 7;12(9):794-800. Epub 2005 Aug 7.

Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1038/nsmb972DOI Listing
September 2005

Translation termination is involved in histone mRNA degradation when DNA replication is inhibited.

Mol Cell Biol 2005 Aug;25(16):6879-88

Department of Biology, University of North Carolina, Chapel Hill, 27599, USA.

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http://dx.doi.org/10.1128/MCB.25.16.6879-6888.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190237PMC
August 2005

Nuclear import of the stem-loop binding protein and localization during the cell cycle.

Mol Biol Cell 2005 Jun 13;16(6):2960-71. Epub 2005 Apr 13.

Program in Molecular Biology and Biotechnology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1091/mbc.e04-11-1023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142439PMC
June 2005

Metazoan replication-dependent histone mRNAs: a distinct set of RNA polymerase II transcripts.

Curr Opin Cell Biol 2005 Jun;17(3):274-80

Program in Molecular Biology and Biotechnology, Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1016/j.ceb.2005.04.010DOI Listing
June 2005

A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100.

Mol Cell Biol 2005 Feb;25(4):1489-500

Program in Molecular Biology and Biotechnology, CB #3280, University of North Carolina, Chapel Hill, NC 27599.

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http://dx.doi.org/10.1128/MCB.25.4.1489-1500.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548002PMC
February 2005

Nuclear export of metazoan replication-dependent histone mRNAs is dependent on RNA length and is mediated by TAP.

RNA 2005 Jan;11(1):45-58

Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1261/rna.7189205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370690PMC
January 2005

string(cdc25) and cyclin E are required for patterned histone expression at different stages of Drosophila embryonic development.

Dev Biol 2004 Oct;274(1):82-93

Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.ydbio.2004.06.019DOI Listing
October 2004

SLBP is associated with histone mRNA on polyribosomes as a component of the histone mRNP.

Nucleic Acids Res 2004 9;32(16):4833-42. Epub 2004 Sep 9.

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1093/nar/gkh798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC519100PMC
September 2004

The N-terminal domain of the Drosophila histone mRNA binding protein, SLBP, is intrinsically disordered with nascent helical structure.

Biochemistry 2004 Jul;43(29):9390-400

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1021/bi036314rDOI Listing
July 2004

Electrostatic contribution of serine phosphorylation to the Drosophila SLBP--histone mRNA complex.

Biochemistry 2004 Jul;43(29):9401-12

Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1021/bi036315jDOI Listing
July 2004