William M Gallagher

William M Gallagher

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William M Gallagher

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RGD conjugated cell uptake off to on responsive NIR-AZA fluorophores: applications toward intraoperative fluorescence guided surgery.

Chem Sci 2019 Aug 21;10(29):6944-6956. Epub 2019 Jun 21.

Department of Chemistry , RCSI , 123 St. Stephen's Green , Dublin 2 , Ireland . Email:

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http://dx.doi.org/10.1039/c9sc02197cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6686729PMC
August 2019

Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate.

Proteomics Clin Appl 2019 07 19;13(4):e1800159. Epub 2019 Mar 19.

RCSI Centre for Systems Medicine, Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, D02 HX03, Ireland.

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http://dx.doi.org/10.1002/prca.201800159DOI Listing
July 2019

Durability of cell line xenograft resection models to interrogate tumor micro-environment targeting agents.

Sci Rep 2019 Jun 24;9(1):9204. Epub 2019 Jun 24.

Department of Physiology and Medical Physics, Centre for Systems Medicine, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/s41598-019-45444-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591410PMC
June 2019

PEGylated BF-Azadipyrromethene (NIR-AZA) fluorophores, for intraoperative imaging.

Eur J Med Chem 2019 Jan 19;161:343-353. Epub 2018 Oct 19.

Department of Chemistry, RCSI, 123 St. Stephen's Green, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.10.046DOI Listing
January 2019

Low cleaved caspase-7 levels indicate unfavourable outcome across all breast cancers.

J Mol Med (Berl) 2018 10 1;96(10):1025-1037. Epub 2018 Aug 1.

RCSI Centre for Systems Medicine, Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/s00109-018-1675-0DOI Listing
October 2018

Epigenetics of malignant melanoma.

Semin Cancer Biol 2018 08 23;51:80-88. Epub 2017 Oct 23.

Cancer Biology and Therapeutics Laboratory, UCD School of Biomolecular and Biomedical Research, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland; OncoMark Limited, NovaUCD, Belfield Innovation Park, Dublin 4, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S1044579X173013
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http://dx.doi.org/10.1016/j.semcancer.2017.10.006DOI Listing
August 2018

Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab.

J Clin Oncol 2018 07 24;36(20):2052-2060. Epub 2018 May 24.

Erik van Dijk, Hedde D. Biesma, Martijn Cordes, Maarten Neerincx, Paul P. Eijk, Henk M.W. Verheul, Nicole C.T. van Grieken, and Bauke Ylstra, Vrije Universiteit Medical Center; Gerrit A. Meijer, Netherlands Cancer Institute; Cornelis J.A. Punt, Academic Medical Center, Amsterdam; Miriam Koopman, University Medical Center Utrecht, Utrecht, the Netherlands; Dominiek Smeets and Diether Lambrechts, KU Leuven, Leuven, Belgium; Sudipto Das, Orna Bacon, Jochen H.M. Prehn, Bryan T. Hennessey, Darran P. O'Connor, and Annette T. Byrne, Royal College of Surgeons in Ireland; Verena Murphy, Cancer Trials Ireland; Anna Barat, Deborah A. McNamara, and Elaine W. Kay, Beaumont Hospital; Bozena Fender and William M. Gallagher, OncoMark Ltd; Rut Klinger and William M. Gallagher, University College Dublin, Dublin, United Kingdom; Johannes Betge, Timo Gaiser, and Matthias P.A. Ebert, University Hospital Mannheim, Mannheim, Germany; and Fotios Loupakis, Veneto Institute of Oncology IOV-IRCCS Padua, Italy.

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http://dx.doi.org/10.1200/JCO.2017.77.1782DOI Listing
July 2018

Absolute Quantification of Toxicological Biomarkers via Mass Spectrometry.

Methods Mol Biol 2017 ;1641:337-348

UCD School of Medicine and Medical Science, UCD Conway Institute, Belfield, Dublin, Ireland.

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http://link.springer.com/10.1007/978-1-4939-7172-5_19
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http://dx.doi.org/10.1007/978-1-4939-7172-5_19DOI Listing
April 2018

Mutant p53 as a therapeutic target for the treatment of triple-negative breast cancer: Preclinical investigation with the anti-p53 drug, PK11007.

Cancer Lett 2018 02 22;414:99-106. Epub 2017 Oct 22.

UCD School of Medicine, University College Dublin, Dublin 4, Ireland; UCD Clinical Research Centre, St. Vincent's University Hospital, Dublin 4, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.09.053DOI Listing
February 2018

Assessment of Significance of Novel Proteins in Breast Cancer Using Tissue Microarray Technology.

Methods Mol Biol 2017 ;1501:311-325

RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, 123 St. Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-6475-8_16DOI Listing
January 2018

Circulating MicroRNAs in Cancer.

Methods Mol Biol 2017 ;1509:123-139

Discipline of Surgery, Lambe Institute for Translational Research, National University of Ireland Galway, Galway, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-6524-3_12DOI Listing
January 2018

Master Transcriptional Regulators in Cancer: Discovery via Reverse Engineering Approaches and Subsequent Validation.

Cancer Res 2017 05 20;77(9):2186-2190. Epub 2017 Apr 20.

Cancer Biology and Therapeutics Laboratory, UCD School of Biomolecular and Biomedical Research, UCD Conway Institute, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1813DOI Listing
May 2017

The Emerging Role of Non-traditional Ubiquitination in Oncogenic Pathways.

J Biol Chem 2017 03 1;292(9):3543-3551. Epub 2017 Feb 1.

From Molecular and Cellular Therapeutics and

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http://dx.doi.org/10.1074/jbc.R116.755694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339741PMC
March 2017

Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer.

Expert Rev Mol Diagn 2016 16;16(5):541-51. Epub 2016 Mar 16.

b Department of Physiology and Medical Physics , Royal College of Surgeons in Ireland , Dublin 2 , Ireland.

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http://dx.doi.org/10.1586/14737159.2016.1156534DOI Listing
December 2016

Prognostic and predictive biomarkers in melanoma: an update.

Expert Rev Mol Diagn 2016 22;16(2):223-37. Epub 2015 Dec 22.

a OncoMark Ltd., NovaUCD, Bellfield , University College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.1586/14737159.2016.1126511DOI Listing
November 2016

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer.

Front Cell Dev Biol 2016 21;4:103. Epub 2016 Sep 21.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin Dublin, Ireland.

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http://dx.doi.org/10.3389/fcell.2016.00103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030284PMC
September 2016

RE: RNA Disruption Assay as a Biomarker of Pathological Complete Response in Neoadjuvant Trastuzumab-Treated Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer.

J Natl Cancer Inst 2016 08 4;108(8). Epub 2016 Jul 4.

Medical Oncology Group, Dept. of Molecular Medicine (ST, AJE, RK, BTH), Department of Pathology (JF, AO, RC, EK), Molecular and Cellular Therapeutics (DO), and Endocrine Oncology Research Group, Department of Surgery (LY), Royal College of Surgeons in Ireland, Dublin, Ireland; RNA Diagnostics Inc., Toronto, Ontario, Canada (LBP, KPHP); Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada (KPHP); Department of Oncology, Beaumont Hospital, Dublin, Ireland (LG, BTH); Department of Oncology, St. James Hospital, Dublin, Ireland (JK); Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland (NO, JC); School of Biomolecular & Biomedical Science, Conway Institute, University College Dublin, Dublin, Ireland (WMG); Department of Medical Oncology, St Vincent's University Hospital, Dublin, Ireland (JC); All Ireland Clinical Oncology Research Group (BTH).

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http://dx.doi.org/10.1093/jnci/djw111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017949PMC
August 2016

De novo post-diagnosis statin use, breast cancer-specific and overall mortality in women with stage I-III breast cancer.

Br J Cancer 2016 08 2;115(5):592-8. Epub 2016 Aug 2.

Department of Pharmacology and Therapeutics, Trinity Centre for Health Sciences, Trinity College, University of Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/bjc.2016.232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997555PMC
August 2016

Functionalization of emissive conjugated polymer nanoparticles by coprecipitation: consequences for particle photophysics and colloidal properties.

Nanotechnology 2016 Jul 16;27(30):305603. Epub 2016 Jun 16.

School of Chemistry, University College Dublin, Dublin, Ireland. The University of Texas at Austin, McKetta Department of Chemical Engineering, 200 E Dean Keeton St. Stop, C0400, Austin, TX 78712-1589, USA.

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http://dx.doi.org/10.1088/0957-4484/27/30/305603DOI Listing
July 2016

Lysosome triggered near-infrared fluorescence imaging of cellular trafficking processes in real time.

Nat Commun 2016 Mar 1;7:10855. Epub 2016 Mar 1.

Department of Pharmaceutical and Medicinal Chemistry, Royal College of Surgeons in Ireland, 123 St Stephen's Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/ncomms10855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773516PMC
March 2016

The Role of Exosomes in Breast Cancer.

Clin Chem 2015 Dec 14;61(12):1457-65. Epub 2015 Oct 14.

School of Pharmacy and Pharmaceutical Sciences & Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland;

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http://dx.doi.org/10.1373/clinchem.2015.240028DOI Listing
December 2015

Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer.

Eur Respir J 2015 Dec 5;46(6):1762-72. Epub 2015 Nov 5.

Thoracic Oncology Research Group, Trinity College Dublin, Dublin, Ireland Princess Alexandra Hospital and Queensland University of Technology, Brisbane, Australia

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http://dx.doi.org/10.1183/13993003.00176-2014DOI Listing
December 2015

Relationship between serum response factor and androgen receptor in prostate cancer.

Prostate 2015 Nov 7;75(15):1704-17. Epub 2015 Aug 7.

UCDSchool of Medicine and Medical Science, Conway Institute of Biomolecular Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/pros.23051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579008PMC
November 2015

Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.

Nat Med 2015 Jul 1;21(7):741-50. Epub 2015 Jun 1.

1] Cancer Epigenetics and Biology Program, Bellvitge Biomedical Research Institute, L'Hospitalet, Barcelona, Catalonia, Spain. [2] Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain. [3] Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1038/nm.3863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968631PMC
July 2015

High-throughput oncogene mutation profiling shows demographic differences in BRAF mutation rates among melanoma patients.

Melanoma Res 2015 Jun;25(3):189-99

aOncoMark Ltd, NovaUCD bDepartment of Medical Oncology, Royal College of Surgeons cUCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin Departments of dPathology eSurgery fMedical Oncology, St Vincent's University Hospital gDepartment of Histopathology, Royal College of Surgeons in Ireland Education and Research Centre, Beaumont Hospital hDepartment of Histopathology, St James's Hospital iDepartment of Histopathology, Trinity College, Dublin jDepartment of Pathology, Cork University Hospital, Cork Departments of kSurgery lMedical Oncology, University Hospital Galway mDepartment of Medicine, National University of Ireland Galway nDepartment of Histopathology, University Hospital Galway, Galway, Ireland oDepartment of Pathology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht, The Netherlands pLaboratory of Morphology and Molecular Pathology, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/CMR.0000000000000149DOI Listing
June 2015

The chain length of biologically produced (R)-3-hydroxyalkanoic acid affects biological activity and structure of anti-cancer peptides.

J Biotechnol 2015 Jun 24;204:7-12. Epub 2015 Mar 24.

School of Biomolecular and Biomedical Sciences and Centre for Synthesis and Chemical Biology, UCD Conway Institute, University College Dublin, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2015.02.036DOI Listing
June 2015

Commercialized biomarkers: new horizons in prostate cancer diagnostics.

Expert Rev Mol Diagn 2015 Apr 24;15(4):491-503. Epub 2015 Feb 24.

UCD School of Medicine and Medical Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1586/14737159.2015.1011622DOI Listing
April 2015

A novel mechanism of regulation of the anti-metastatic miR-31 by EMSY in breast cancer.

Breast Cancer Res 2014 Nov 18;16(6):467. Epub 2014 Nov 18.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/s13058-014-0467-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429417PMC
November 2014

OvMark: a user-friendly system for the identification of prognostic biomarkers in publically available ovarian cancer gene expression datasets.

Mol Cancer 2014 Oct 24;13:241. Epub 2014 Oct 24.

Molecular Therapeutics for Cancer Ireland, National Institute for Cellular Biotechnology, Dublin City University, Glasnevin, Dublin 9, Ireland.

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http://dx.doi.org/10.1186/1476-4598-13-241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219121PMC
October 2014

Garbage in, garbage out: a critical evaluation of strategies used for validation of immunohistochemical biomarkers.

Mol Oncol 2014 Jun 21;8(4):783-98. Epub 2014 Mar 21.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.molonc.2014.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528533PMC
June 2014

microRNAs: a new class of breast cancer biomarkers.

Expert Rev Mol Diagn 2014 Apr;14(3):347-63

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1586/14737159.2014.901153DOI Listing
April 2014

The analysis of serum response factor expression in bone and soft tissue prostate cancer metastases.

Prostate 2014 Feb;74(3):306-13

OncoMark Ltd, Nova UCD, University College Dublin, Belfield, Dublin 4, Ireland; Department of Pathology, RCSI Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland.

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http://doi.wiley.com/10.1002/pros.22752
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http://dx.doi.org/10.1002/pros.22752DOI Listing
February 2014

miRNA dysregulation in breast cancer.

Cancer Res 2013 Nov 7;73(22):6554-62. Epub 2013 Nov 7.

Authors' Affiliation: UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1841DOI Listing
November 2013

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

Breast Cancer Res 2013 Oct 1;15(5):R92. Epub 2013 Oct 1.

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http://dx.doi.org/10.1186/bcr3493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907091PMC
October 2013

Identification of transcription factors associated with castration-resistance: is the serum responsive factor a potential therapeutic target?

Prostate 2013 May 28;73(7):743-53. Epub 2013 Jan 28.

UCD School of Medicine and Medical Science, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1002/pros.22618DOI Listing
May 2013

The anti-cancer activity of a cationic anti-microbial peptide derived from monomers of polyhydroxyalkanoate.

Biomaterials 2013 Apr 21;34(11):2710-8. Epub 2013 Jan 21.

School of Biomolecular and Biomedical Sciences and Centre for Synthesis and Chemical Biology, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.biomaterials.2012.12.032DOI Listing
April 2013

Development of a pharmaceutical hepatotoxicity biomarker panel using a discovery to targeted proteomics approach.

Mol Cell Proteomics 2012 Aug 23;11(8):394-410. Epub 2012 Apr 23.

UCD School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1074/mcp.M111.016493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412970PMC
August 2012

Tumor profiling using protein biomarker panels in malignant melanoma: application of tissue microarrays and beyond.

Expert Rev Proteomics 2012 Aug;9(4):415-23

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://www.tandfonline.com/doi/full/10.1586/epr.12.5
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http://dx.doi.org/10.1586/epr.12.5DOI Listing
August 2012

Focus on cancer proteomics.

Proteomics 2012 Jul;12(13):2065-6

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http://dx.doi.org/10.1002/pmic.201270084DOI Listing
July 2012

Proteomic portrait of human breast cancer progression identifies novel prognostic markers.

Cancer Res 2012 May 13;72(9):2428-39. Epub 2012 Mar 13.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3711DOI Listing
May 2012

Generation of a new bioluminescent model for visualisation of mammary tumour development in transgenic mice.

BMC Cancer 2012 May 30;12:209. Epub 2012 May 30.

Cancer Biology and Therapeutics Group, UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/1471-2407-12-209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411433PMC
May 2012

Mechanism of cell death mediated by a BF2-chelated tetraaryl-azadipyrromethene photodynamic therapeutic: dissection of the apoptotic pathway in vitro and in vivo.

Int J Cancer 2012 Feb 26;130(3):705-15. Epub 2011 May 26.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1002/ijc.26073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568043PMC
February 2012

A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.

Cancer Res 2012 Jan 7;72(1):66-75. Epub 2011 Nov 7.

Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, Cancer Research UK, Bioinformatics and Biostatistics Service, London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252703PMC
January 2012

Serum proteomic profiling reveals that pretreatment complement protein levels are predictive of esophageal cancer patient response to neoadjuvant chemoradiation.

Ann Surg 2011 Nov;254(5):809-16; discussion 816-7

Department of Surgery, Institute of Molecular Medicine, Trinity Centre for Health Science, Trinity College Dublin, St. James's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1097/SLA.0b013e31823699f2DOI Listing
November 2011

Characterisation and manipulation of docetaxel resistant prostate cancer cell lines.

Mol Cancer 2011 Oct 7;10:126. Epub 2011 Oct 7.

UCD School of Medicine and Medical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1186/1476-4598-10-126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203088PMC
October 2011

Truncated HER2: implications for HER2-targeted therapeutics.

Drug Discov Today 2011 Sep 16;16(17-18):810-6. Epub 2011 Jun 16.

Cancer Biology and Therapeutics Group, UCD Conway Institute, UCD School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.

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https://linkinghub.elsevier.com/retrieve/pii/S13596446110018
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http://dx.doi.org/10.1016/j.drudis.2011.06.003DOI Listing
September 2011

Evaluation of the prognostic significance of MSMB and CRISP3 in prostate cancer using automated image analysis.

Mod Pathol 2011 May 14;24(5):708-19. Epub 2011 Jan 14.

Department of Clinical Sciences, Division of Urological Cancers, Lund University, Skåne University Hospital, Malmö, Sweden.

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http://dx.doi.org/10.1038/modpathol.2010.238DOI Listing
May 2011

Functionalized scaffold-mediated interleukin 10 gene delivery significantly improves survival rates of stem cells in vivo.

Mol Ther 2011 May 25;19(5):969-78. Epub 2011 Jan 25.

Network of Excellence for Functional Biomaterials, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1038/mt.2010.311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086863PMC
May 2011

The emerging role of FK506-binding proteins as cancer biomarkers: a focus on FKBPL.

Biochem Soc Trans 2011 Apr;39(2):663-8

School of Pharmacy, McClay Research Centre, Queen's University, Belfast, UK.

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http://dx.doi.org/10.1042/BST0390663DOI Listing
April 2011

The VEGF/Rho GTPase signalling pathway: a promising target for anti-angiogenic/anti-invasion therapy.

Drug Discov Today 2011 Mar 22;16(5-6):219-28. Epub 2011 Jan 22.

Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, Universiteitsweg 99, 3584 CG Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.drudis.2011.01.005DOI Listing
March 2011

Standardization of models and methods used to assess nanoparticles in cardiovascular applications.

Small 2011 Mar 11;7(6):705-17. Epub 2011 Feb 11.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1002/smll.201001347DOI Listing
March 2011

Absolute quantification of toxicological biomarkers by multiple reaction monitoring.

Methods Mol Biol 2011 ;691:417-27

UCD School of Biomolecular and Biomedical Science and Proteome Research Centre, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1007/978-1-60761-849-2_25DOI Listing
February 2011

Early proteomic analysis may allow noninvasive identification of hepatitis C response to treatment with pegylated interferon α-2b and ribavirin.

Eur J Gastroenterol Hepatol 2011 Feb;23(2):177-83

Centre for Liver Disease, Mater Misericordiae University Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/MEG.0b013e3283424e3eDOI Listing
February 2011

Sequence tagging reveals unexpected modifications in toxicoproteomics.

Chem Res Toxicol 2011 Feb 7;24(2):204-16. Epub 2011 Jan 7.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee 37232-0006, United States.

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http://dx.doi.org/10.1021/tx100275tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042045PMC
February 2011

Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.

Breast Cancer Res 2011 Jan 31;13(1):R12. Epub 2011 Jan 31.

UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1186/bcr2820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109580PMC
January 2011

Focus on cancer proteomics: from discovery towards validation.

Proteomics Clin Appl 2010 Jul;4(6-7):577-8

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http://dx.doi.org/10.1002/prca.201090020DOI Listing
July 2010