William L Carroll

William L Carroll

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William L Carroll

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Mechanisms of -Mediated Thiopurine Resistance in Acute Lymphoblastic Leukemia.

Mol Cancer Ther 2019 Oct 29;18(10):1887-1895. Epub 2019 Jul 29.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1535-7163.MCT-18-1112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774896PMC
October 2019

Influences Antimetabolite Drug Sensitivity and Prognosis of Acute Lymphoblastic Leukemia.

Clin Cancer Res 2019 Oct 1. Epub 2019 Oct 1.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0190DOI Listing
October 2019

Immune-Based Therapies in Acute Leukemia.

Trends Cancer 2019 Oct 29;5(10):604-618. Epub 2019 Aug 29.

Department of Pathology, New York University School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.trecan.2019.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859901PMC
October 2019

From Favorable Histology to Relapse: The Clonal Evolution of a Wilms Tumor.

Pediatr Dev Pathol 2019 Sep 16:1093526619875919. Epub 2019 Sep 16.

Department of Pediatrics, Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, New York.

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http://dx.doi.org/10.1177/1093526619875919DOI Listing
September 2019

Bortezomib reinduction chemotherapy in high-risk ALL in first relapse: a report from the Children's Oncology Group.

Br J Haematol 2019 Jul 7;186(2):274-285. Epub 2019 Apr 7.

Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/bjh.15919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606340PMC
July 2019

Targeting a major hub of cell fate decisions - the mitochondrial-associated membrane.

Haematologica 2019 Mar;104(3):419-421

Departments of Pediatrics and Pathology, Perlmutter Cancer Center, NYU-Langone Medical Center, New York, NY, USA.

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http://dx.doi.org/10.3324/haematol.2018.208355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395318PMC
March 2019

Improved Survival for Children and Young Adults With T-Lineage Acute Lymphoblastic Leukemia: Results From the Children's Oncology Group AALL0434 Methotrexate Randomization.

J Clin Oncol 2018 10 23;36(29):2926-2934. Epub 2018 Aug 23.

Stuart S. Winter, Children's Minnesota Cancer and Blood Disorders Program, Minneapolis, MN; Kimberly P. Dunsmore, Carilion Clinic, Roanoke, VA; Meenakshi Devidas and Zhiguo Chen, University of Florida, Gainesville, FL; Brent L. Wood, Seattle Children's Hospital, Seattle, WA; Natia Esiashvili, Emory University, Atlanta, GA; Nancy Eisenberg, University of New Mexico Health Sciences Center, Albuquerque, NM; Nikki Briegel, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Robert J. Hayashi, St Louis Children's Hospital, St Louis, MO; Julie M. Gastier-Foster, Nationwide Children's Hospital; Julie M. Gastier-Foster and Nyla A. Heerema, Ohio State University, Columbus, OH; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Barbara L. Asselin, University of Rochester Medical Center and Wilmot Cancer Institute, Rochester; Elizabeth A. Raetz and William L. Carroll, Perlmutter Cancer Center at NYU Langone Health, New York, NY; Paul S. Gaynon, Children's Hospital of Los Angeles, Los Angeles; Mignon L. Loh, University of California, San Francisco, San Francisco, CA; Michael J. Borowitz, Johns Hopkins University, Baltimore, MD; Karen R. Rabin, Baylor College of Medicine, Houston; Naomi J. Winick, University of Texas Southwestern, Dallas, TX; Patrick A. Zweidler-Mckay, ImmunoGen, Waltham, MA; and Stephen P. Hunger, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2018.77.7250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366301PMC
October 2018

Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.

J Clin Oncol 2018 08 29;36(22):2306-2314. Epub 2018 May 29.

William B. Slayton, John A. Kairalla, Meenakshi Devidas, Xinlei Mi, and Sherri L. Mizrahy, University of Florida, Gainesville, FL; Kirk R. Schultz, BC Children's Research Institute, University of British Columbia, Vancouver, British Columbia, Canada; Michael A. Pulsipher, Children's Hospital of Los Angeles, Los Angeles; Lance Sieger, University of California Los Angles-Harbor, Torrance; Mignon L. Loh, University of California San Francisco, San Francisco, CA; Bill H. Chang, Oregon Health and Science University, Portland, OR; Charles Mullighan, Ilaria Iacobucci, and Thomas Merchant, St Jude's Research Hospital, Memphis, TN; Lewis B. Silverman, Dana-Farber Cancer Institute, Boston, MA; Michael J. Borowitz, Johns Hopkins University, Baltimore, MD; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Nyla A. Heerema, Ohio State University; Julie M. Gastier-Foster, Nationwide Children's Hospital, Columbus, OH; Brent L. Wood, University of Washington Seattle, Seattle, WA; Valerie I. Brown, Penn State Health Children's Hospital, Hershey; Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA; Marilyn J. Siegel, Washington University School of Medicine, St Louis, MO; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; and William L. Carroll, New York University Langone Health Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2017.76.7228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067800PMC
August 2018

The ASPHO 2018 Distinguished Career Award goes to Dr. Michael P. Link.

Pediatr Blood Cancer 2018 06 31;65 Suppl 1:e26987. Epub 2018 Jan 31.

Department of Pediatrics, Division of Oncology, and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/pbc.26987DOI Listing
June 2018

Relapsed acute lymphoblastic leukemia-specific mutations in NT5C2 cluster into hotspots driving intersubunit stimulation.

Leukemia 2018 06 25;32(6):1393-1403. Epub 2018 Feb 25.

Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Flemingovo nam. 2, Prague 6, 166 10, Czech Republic.

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http://dx.doi.org/10.1038/s41375-018-0073-5DOI Listing
June 2018

TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.

J Clin Oncol 2018 02 4;36(6):591-599. Epub 2018 Jan 4.

Maoxiang Qian, Xueyuan Cao, Wenjian Yang, Cheng Cheng, Hui Zhang, Takaya Moriyama, Gerard Zambetti, Kim E. Nichols, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Mary V. Relling, and Jun J. Yang, St Jude Children's Research Hospital, Memphis, TN; Meenakshi Devidas and Yunfeng Dai, University of Florida, Gainesville, FL; Andrew Carroll, University of Alabama at Birmingham, Birmingham, AL; Nyla A. Heerema and Julie M. Gastier-Foster, The Ohio State University and Wexner Medical Center; Julie M. Gastier-Foster and Elaine R. Mardis, Nationwide Children's Hospital, Columbus, OH; Hui Zhang, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong; Heng Xu, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China; Elizabeth Raetz, University of Utah, Salt Lake City, UT; Eric Larsen, Maine Children's Cancer Program, Scarborough, ME; Naomi Winick, University of Texas Southwestern Medical Center, Dallas; W. Paul Bowman, Cook Children's Medical Center, Fort Worth, TX; Paul L. Martin, Duke University, Durham, NC; Robert Fulton, Washington University School of Medicine, St Louis, MO; Michael Borowitz, Johns Hopkins Medical Institute, Baltimore, MD; Brent Wood, University of Washington, Seattle, WA; William L. Carroll, New York University, New York, NY; Stephen P. Hunger, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA; and Mignon L. Loh, Benioff Children's Hospital and University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2017.75.5215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815403PMC
February 2018

Klinefelter syndrome and 47,XYY syndrome in children with B cell acute lymphoblastic leukaemia.

Br J Haematol 2017 12 19;179(5):843-846. Epub 2016 Jul 19.

Department of Pediatrics and the Center for Childhood Cancer Research, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1111/bjh.14258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247399PMC
December 2017

Reply to I.J. Cohen.

J Clin Oncol 2017 12 18;35(35):3989-3991. Epub 2017 Oct 18.

Kristina K. Hardy, Children's National Medical Center, Washington, DC; Leanne M. Embry, University of Texas at San Antonio, San Antonio, TX; John A. Kairalla, University of Florida, Gainesville, FL; Shanjun Helian, Merck, Upper Gwynedd, PA; Meenakshi Devidas, University of Florida, Gainesville, FL; F. Daniel Armstrong, University of Miami, Miami, FL; Stephen Hunger, Children's Hospital of Philadelphia, Philadelphia, PA; William L. Carroll, New York University, New York, NY; Eric Larsen, Maine Children's Cancer Program, Scarborough, ME; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; Mignon L. Loh, University of California at San Francisco, San Francisco, CA; Wenjian Yang and Mary V. Relling, St Jude Children's Research Hospital and University of Tennessee, Memphis, TN; Robert B. Noll, University of Pittsburgh, Pittsburgh, PA; and Naomi Winick, University of Texas Southwestern, Dallas, TX.

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http://dx.doi.org/10.1200/JCO.2017.75.7252DOI Listing
December 2017

Impact of Initial CSF Findings on Outcome Among Patients With National Cancer Institute Standard- and High-Risk B-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group.

J Clin Oncol 2017 Aug 23;35(22):2527-2534. Epub 2017 May 23.

Naomi Winick, University of Texas Southwestern Medical Center, Dallas, TX; Meenakshi Devidas and Si Chen, University of Florida, Gainesville, FL; Kelly Maloney, Children's Hospital Colorado, Aurora, CO; Eric Larsen, Maine Children's Cancer Program, Scarborough, ME; Leonard Mattano, HARP Pharma Consulting, Mystic, CT; Michael J. Borowitz, Johns Hopkins Medical Institutions, Baltimore, MD; Andrew Carroll, University of Alabama at Birmingham, AL; Julie M. Gastier-Foster, Institute for Genomic Medicine, Nationwide Children's Hospital; Julie M. Gastier-Foster and Nyla A. Heerema, The Ohio State University School of Medicine, Columbus, OH; Cheryl Willman, University of New Mexico, Albuquerque, NM; Brent Wood, University of Washington, Seattle, WA; Mignon L. Loh, University of California, San Francisco, San Francisco, CA; Elizabeth Raetz, University of Utah, Salt Lake City, UT; Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA; and William L. Carroll, New York University Medical Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.4774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536164PMC
August 2017

New targeted therapies for relapsed pediatric acute lymphoblastic leukemia.

Expert Rev Anticancer Ther 2017 08 5;17(8):725-736. Epub 2017 Jul 5.

a Division of Pediatric Hematology Oncology, Department of Pediatrics , Perlmutter Cancer Center, NYU Langone Medical Center , New York , NY , USA.

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http://dx.doi.org/10.1080/14737140.2017.1347507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028000PMC
August 2017

Neurocognitive Functioning of Children Treated for High-Risk B-Acute Lymphoblastic Leukemia Randomly Assigned to Different Methotrexate and Corticosteroid Treatment Strategies: A Report From the Children's Oncology Group.

J Clin Oncol 2017 Aug 3;35(23):2700-2707. Epub 2017 Jul 3.

Kristina K. Hardy, Children's National Medical Center, Washington, DC; Leanne Embry, The University of Texas Health Science Center at San Antonio, San Antonio; Naomi Winick, University of Texas Southwestern Medical Center, Dallas, TX; John A. Kairalla and Meenakshi Devidas, Colleges of Medicine, Public Health and Health Professions, University of Florida, Gainesville; Daniel Armstrong, University of Miami, Sylvester Comprehensive Cancer Center, Miami, FL; Shanjun Helian, Merck, Upper Gwynedd; Stephen Hunger, Children's Hospital of Philadelphia, Philadelphia; Robert B. Noll, University of Pittsburgh School of Medicine, Pittsburgh, PA; William L. Carroll, New York University Medical Center, New York, NY; Eric Larsen, Maine Children's Cancer Program, Scarborough, ME; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; Mignon L. Loh, University of California, San Francisco, San Francisco, CA; and Wenjian Yang and Mary V. Relling, St Jude Children's Research Hospital; University of Tennessee Health Science Center, Memphis, TN.

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http://dx.doi.org/10.1200/JCO.2016.71.7587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549456PMC
August 2017

Mercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group Study AALL03N1.

J Clin Oncol 2017 May 24;35(15):1730-1736. Epub 2017 Mar 24.

Wendy Landier, Lindsey Hageman, Yanjun Chen, and Smita Bhatia, University of Alabama at Birmingham, Birmingham, AL; Nancy Kornegay, William E. Evans, and Mary V. Relling, St. Jude Children's Research Hospital, Memphis, TN; Bruce C. Bostrom, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN; Jacqueline Casillas, David Geffen School of Medicine at University of California Los Angeles, Los Angeles; Leo Mascarenhas and Amanda M. Termuhlen, Children's Hospital Los Angeles, Los Angeles; F. Lennie Wong, City of Hope, Duarte, CA; David S. Dickens, Helen DeVos Children's Hospital at Spectrum Health/Spectrum Health at Butterworth Campus, Grand Rapids, MI; Anne L. Angiolillo, The George Washington School of Medicine, Washington, DC; Glen Lew, Children's Healthcare of Atlanta, Emory University, Atlanta, GA; Kelly W. Maloney, University of Colorado School of Medicine, Aurora, CO; A. Kim Ritchey, Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, PA; and William L. Carroll, Perlmutter Cancer Center, New York University-Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.71.7579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455766PMC
May 2017

Beating the Clock in T-cell Acute Lymphoblastic Leukemia.

Clin Cancer Res 2017 Feb 22;23(4):873-875. Epub 2016 Dec 22.

Department of Pediatrics, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2825DOI Listing
February 2017

Decitabine enhances chemosensitivity of early T-cell precursor-acute lymphoblastic leukemia cell lines and patient-derived samples.

Leuk Lymphoma 2016 08 4;57(8):1938-41. Epub 2016 Jan 4.

b Perlmutter Cancer Center , New York University Langone Medical Center , New York , NY , USA ;

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http://dx.doi.org/10.3109/10428194.2015.1110747DOI Listing
August 2016

A Pilot Study of Intensified PEG-Asparaginase in High-risk Acute Lymphoblastic Leukemia: Children's Oncology Group Study AALL08P1.

J Pediatr Hematol Oncol 2016 08;38(6):409-17

*Mayo Clinic Children's Center, Division of Pediatric Hematology Oncology, Rochester, MN †Children's Oncology Group Data Center Biostatistics, University of Florida, Gainesville, FL ‡Walter Reed National Military Medical Center, Congressionally Directed Medical Research Program, US Army Medical Research and Materiel Command, Fort Detrick, MD ††Department of Pathology, Johns Hopkins University Sidney Kimmel Cancer Center, John Hopkins University, Baltimore, MD §Division Pediatric Hematology-Oncology, Primary Children's Hospital, University of Utah, Salt Lake City, UT ∥Division of Pediatric Hematology Oncology, UCSF Medical Center-Mssion Bay, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA ¶Department of Genetics, Children's Hospital of Alabama, University of Alabama at Birmingham, Birmingham, AL #Nationwide Children's Hospital, Cytogenetics, The Ohio State University, Columbus, OH **Seattle Children's Hospital, Laboratory Medicine, Seattle, WA ‡‡Midwest Children's Cancer Center, MACC Fund Research Center, Milwaukee, WI §§Division of Pediatric Hematology Oncology, University of Rochester Medical Center, Rochester ¶¶Laura and Isaac Perlmutter Cancer Center at NYU Langone, Hassendfeld Children's Center, New York, NY ∥∥Division Pediatric Hematology-Oncology, UT Southwestern/Simmons Cancer Center, Dallas, TX †††Baylor College of Medicine, Comprehensive Cancer Center, Pediatric Oncology, Houston, TX ##Division of Oncology, Children's Hospital of Philadelphia ***Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/MPH.0000000000000589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955695PMC
August 2016

Dexamethasone and High-Dose Methotrexate Improve Outcome for Children and Young Adults With High-Risk B-Acute Lymphoblastic Leukemia: A Report From Children's Oncology Group Study AALL0232.

J Clin Oncol 2016 07 25;34(20):2380-8. Epub 2016 Apr 25.

Eric C. Larsen, Maine Children's Cancer Program, Scarborough, ME; Meenakshi Devidas and Si Chen, University of Florida, Gainesville, FL; Wanda L. Salzer, US Army Medical Research and Materiel Command, Frederick; Michael J. Borowitz, Johns Hopkins Medical Institutions, Baltimore, MD; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT, Mignon L. Loh, University of California, San Francisco, San Francisco, CA; Leonard A. Mattano Jr, HARP Pharma Consulting, Mystic, CT; Catherine Cole, Princess Margaret Hospital for Children; University of Western Australia, Perth, Western Australia, Australia; Alisa Eicher, Doernbecher Children's Hospital, Portland, OR; Maureen Haugan, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Mark Sorenson, University of Iowa Hospitals and Clinics, Iowa City, IA; Nyla A. Heerema and Julie M. Gastier-Foster, The Ohio State University School of Medicine, Columbus, OH; Andrew A. Carroll, University of Alabama at Birmingham, Birmingham, AL; Brent L. Wood, University of Washington, Seattle, WA; Cheryl L. Willman, University of New Mexico, Albuquerque, NM; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; Stephen P. Hunger, Children's Hospital of Philadelphia; University of Pennsylvania, Philadelphia, PA; and William L. Carroll, New York University Medical Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2015.62.4544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981974PMC
July 2016

Progress and Prospects in Pediatric Leukemia.

Curr Probl Pediatr Adolesc Health Care 2016 Jul 6;46(7):229-241. Epub 2016 Jun 6.

Division of Pediatric Hematology Oncology, Department of Pediatrics, Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1016/j.cppeds.2016.04.003DOI Listing
July 2016

Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia.

J Clin Oncol 2016 06 25;34(18):2133-40. Epub 2016 Apr 25.

Chengcheng Liu, Wenjian Yang, Cheng Cheng, Deqing Pei, Colton Smith, Sima Jeha, Ching-Hon Pui, William E. Evans, and Mary V. Relling, St Jude Children's Research Hospital; Scott C. Howard, University of Memphis, Memphis, TN; Meenakshi Devidas, University of Florida, Gainesville, FL; William L. Carroll, New York University Langone Medical Center, New York, NY; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; W. Paul Bowman, Cook Children's Hospital, Ft Worth; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; Eric C. Larsen, Maine Children's Cancer Program, Scarborough, ME; Kelly W. Maloney, University of Colorado Denver, Aurora, CO; Paul L. Martin, Duke University, Durham, NC; Leonard A. Mattano Jr, HARP Pharma Consulting, Mystic, CT; Elaine R. Mardis and Robert S. Fulton, The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO; Deepa Bhojwani, Children's Hospital of Los Angeles, Los Angeles; Mignon L. Loh, University of California San Francisco Medical Center-Parnassus, San Francisco, CA; and Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2015.64.5812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962704PMC
June 2016

Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells.

ACS Chem Biol 2016 05 1;11(5):1305-12. Epub 2016 Mar 1.

Department of Chemistry, New York University , 100 Washington Square East, New York, New York 10003, United States.

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http://dx.doi.org/10.1021/acschembio.5b00900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507670PMC
May 2016

State of the art discovery with tumor profiling in pediatric oncology.

Am Soc Clin Oncol Educ Book 2015 :e601-7

From the Division of Pediatric Hematology/Oncology, Department of Pediatrics, NYU Langone Medical Center, New York, NY; Perlmutter Cancer Center, NYU Langone Medical Center, New York, NY; Department of Pediatrics, University of Utah, Salt Lake City, UT; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.

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http://dx.doi.org/10.14694/EdBook_AM.2015.35.e601DOI Listing
February 2016

Therapies on the horizon for childhood acute lymphoblastic leukemia.

Curr Opin Pediatr 2016 Feb;28(1):12-8

aDepartment of Pediatrics, Division of Pediatric Hematology/Oncology, Perlmutter Cancer Center, NYU Langone Medical Center, New York bDepartment of Pediatrics, Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia cUniversity of Philadelphia Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755474PMC
February 2016

Genomic Characterization of Poorly Differentiated Neuroendocrine Carcinoma in a Pediatric Patient.

J Pediatr Hematol Oncol 2016 Jan;38(1):e21-5

*Perlmutter Cancer Center at NYU, New York University Langone Medical Center †Department of Pathology, Ichan School of Medicine at Mount Sinai, New York, NY.

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http://dx.doi.org/10.1097/MPH.0000000000000463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681625PMC
January 2016

Pharmacokinetic and pharmacodynamic properties of calaspargase pegol Escherichia coli L-asparaginase in the treatment of patients with acute lymphoblastic leukemia: results from Children's Oncology Group Study AALL07P4.

J Clin Oncol 2014 Dec 27;32(34):3874-82. Epub 2014 Oct 27.

Anne L. Angiolillo, Reuven J. Schore, Ashley R. Lane, and Gregory H. Reaman, Children's National Medical Center, Washington, DC; Meenakshi Devidas, Colleges of Medicine, Public Health and Health Professions, University of Florida; Charlotte Wood and Hao W. Zheng, Children's Oncology Group, Gainesville, FL; Michael J. Borowitz, Johns Hopkins Medical Institutions, Baltimore; Taha Keilani, Sigma-Tau Pharmaceuticals, Gaithersburg, MD; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Julie M. Gastier-Foster and Nyla A. Heerema, Ohio State University Wexner Medical Center; Julie M. Gastier-Foster, Ohio State University College of Medicine and Nationwide Children's Hospital, Columbus, OH; Mignon L. Loh, University of California at San Francisco, San Francisco, CA; Peter C. Adamson, Children's Hospital of Philadelphia, Philadelphia, PA; Brent Wood, University of Washington, Seattle, WA; Elizabeth A. Raetz and William L. Carroll, New York University Cancer Institute, New York University Langone Medical Center, New York, NY; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; and Stephen P. Hunger, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO.

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http://dx.doi.org/10.1200/JCO.2014.55.5763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239306PMC
December 2014

Ikaros deletions in BCR-ABL-negative childhood acute lymphoblastic leukemia are associated with a distinct gene expression signature but do not result in intrinsic chemoresistance.

Pediatr Blood Cancer 2014 Oct 29;61(10):1779-85. Epub 2014 Jun 29.

Department of Pediatric Hematology/Oncology, Laura and Isaac Perlmutter Cancer Center at New York University Langone Medical Center, New York, New York.

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http://dx.doi.org/10.1002/pbc.25119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217284PMC
October 2014

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

N Engl J Med 2014 Sep;371(11):1005-15

From the Departments of Pathology (K.G.R., D.P.-T., Y.-L.Y., K. McCastlain, G.S., J.M., S.-C.C., J.C., N.S.-M., I.I., J.W., J.R.D., C.G.M.), Computational Biology and Bioinformatics (Y.L., J.B., M.R., E.H., P.G., P.N., G.W., X.C., J.Z.), Biostatistics (D.P., C.C.), Pharmaceutical Sciences (S.W.P., M.V.R., W.E.E.), and Oncology (C.-H.P., S.J.), the Pediatric Cancer Genome Project (Y.L., L.D., C.L., M.R., J.E., J.C., K.B., R.S.F., E.H., P.G., P.N., G.W., X.C., D.Y., B.V., H.M., M.V.R., W.E.E., E.M., R.K.W., J.R.D., J.Z., C.G.M.), and Cytogenetics Shared Resource (M.V.), St. Jude Children's Research Hospital, Memphis, TN; the University of New Mexico Cancer Center and School of Medicine, Albuquerque (R.C.H., I-M.C., C.L.W.); the Genome Institute at Washington University (L.D., C.L., R.S.F., E.M., R.K.W.), the Department of Genetics, Washington University School of Medicine (L.D., C.L., R.S.F., E.M., R.K.W.), and Siteman Cancer Center, Washington University (E.M., R.K.W.) - all in St. Louis; Epidemiology and Health Policy Research, College of Medicine, University of Florida, Gainesville (M.D.); the Research Institute at Nationwide Children's Hospital (S.R., A.S., J.M.G.-F.), the Department of Pathology, College of Medicine, Ohio State University (N.A.H.), and Ohio State University Comprehensive Cancer Center (G.M., C.D.B., K. Mrózek, J.K.) - all in Columbus, OH; the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (N.J.W.), Scott and White Hospitals and Clinics and Texas A&M Health Science Center, Temple (G.G.), the University of Texas Health Science Center San Antonio, San Antonio (M.F.-J.), and the Departments of Leukemia and Stem Cell Transplantation, Division of Cancer Medicine, University of Texas M.D. Anderson Cancer Center, Houston (S.M.K., M.K.) - all in Texas; Maine Children's Cancer Program, Scarborough (E.C.L.); New York University Cancer Institute, New York (W.L.C.), and the Department of Medicine (Oncology), Albert Einstein

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http://dx.doi.org/10.1056/NEJMoa1403088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191900PMC
September 2014

A phase I study of EZN-3042, a novel survivin messenger ribonucleic acid (mRNA) antagonist, administered in combination with chemotherapy in children with relapsed acute lymphoblastic leukemia (ALL): a report from the therapeutic advances in childhood leukemia and lymphoma (TACL) consortium.

J Pediatr Hematol Oncol 2014 Aug;36(6):458-63

*NYU Cancer Institute and Department of Pediatrics, NYU Langone Medical Center, New York †Staten Island University Hospital, Staten Island, NY ‡Division of Hematology/Oncology §Department of Preventive Medicine, Keck School of Medicine, University of Southern California ∥Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, CA ¶St. Jude Children's Research Hospital, Memphis, TN #Pediatric Hematology and Oncology, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN **Johns Hopkins University, Baltimore, MD ††Enzon Pharmaceuticals Inc., Piscataway, NJ.

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http://dx.doi.org/10.1097/MPH.0b013e3182a8f58fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238428PMC
August 2014

The biology of relapsed acute lymphoblastic leukemia: opportunities for therapeutic interventions.

J Pediatr Hematol Oncol 2014 Aug;36(6):413-8

Division of Pediatric Hematology-Oncology, New York University Cancer Institute, New York University Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1097/MPH.0000000000000179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264573PMC
August 2014

Epigenetic deregulation in pediatric acute lymphoblastic leukemia.

Epigenetics 2014 Mar 6;9(3):459-67. Epub 2014 Jan 6.

Murdoch Childrens Research Institute; The University of Melbourne Department of Paediatrics at the Royal Children's Hospital; Victoria, VIC Australia.

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http://dx.doi.org/10.4161/epi.27585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053464PMC
March 2014

Refining prognosis in BCR-ABL1-positive ALL.

Blood 2014 Mar;123(11):1626-7

HUNTSMAN CANCER INSTITUTE;

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http://dx.doi.org/10.1182/blood-2014-01-547570DOI Listing
March 2014

Clinical Cancer Advances 2013: Annual Report on Progress Against Cancer from the American Society of Clinical Oncology.

J Clin Oncol 2014 Jan 10;32(2):129-60. Epub 2013 Dec 10.

Jyoti D. Patel, Northwestern University; Blasé Polite, University of Chicago Medicine, Chicago, IL; Lada Krilov, American Society of Clinical Oncology, Alexandria, VA; Sylvia Adams and William L. Carroll, New York University Cancer Institute; Carol Aghajanian, Mark G. Kris, and Gary K. Schwartz, Memorial Sloan-Kettering Cancer Center, New York, NY; Ethan Basch, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC; Marcia S. Brose, University of Pennsylvania Abramson Cancer Center, Philadelphia, PA; Marcos de Lima and Mark R. Gilbert, University of Texas MD Anderson Cancer Center, Houston; Ian Thompson, University of Texas Health Science Center at San Antonio, San Antonio, TX; John L. Marshall, Lombardi Cancer Center, Washington, DC; Gregory A. Masters, Helen F. Graham Cancer Center, Newark, DE; Steven J. O'Day, Beverly Hills Health Center, Beverly Hills, CA; Sunil Sharma, Huntsman Cancer Institute, Salt Lake City, UT; Nicholas J. Vogelzang, US Oncology Research, Comprehensive Cancer Centers of Nevada, Henderson, NV; and Bruce J. Roth, Washington University in St Louis, St Louis, MO.

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http://dx.doi.org/10.1200/JCO.2013.53.7076DOI Listing
January 2014

Intrachromosomal amplification of chromosome 21 is associated with inferior outcomes in children with acute lymphoblastic leukemia treated in contemporary standard-risk children's oncology group studies: a report from the children's oncology group.

J Clin Oncol 2013 Sep 12;31(27):3397-402. Epub 2013 Aug 12.

Nyla A. Heerema and Julie M. Gastier-Foster, The Ohio State University Wexner Medical Center; Julie M. Gastier-Foster, The Ohio State University College of Medicine and Nationwide Children's Hospital, Columbus, OH; Andrew J. Carroll, University of Alabama at Birmingham, Birmingham, AL; Meenakshi Devidas, University of Florida, Gainesville, FL; Mignon L. Loh, University of California at San Francisco, San Francisco, CA; Michael J. Borowitz, Johns Hopkins Medical Institutions, Baltimore, MD; Eric C. Larsen, Maine Children's Cancer Program, Scarborough, ME; Leonard A. Mattano Jr, Michigan State University College of Human Medicine, Kalamazoo, MI; Kelly W. Maloney and Stephen P. Hunger, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO; Cheryl L. Willman, University of New Mexico, Albuquerque, NM; Brent L. Wood, University of Washington, Seattle, WA; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; and William L. Carroll and Elizabeth A. Raetz, The New York University Cancer Institute, New York University Langone Medical Center, New York, NY.

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http://dx.doi.org/10.1200/JCO.2013.49.1308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770866PMC
September 2013

Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia.

Pediatr Blood Cancer 2013 Jun 19;60(6):957-63. Epub 2012 Dec 19.

University of Colorado School of Medicine, The University of Colorado Cancer Center and Children's Hospital Colorado, Aurora, Colorado, USA.

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http://dx.doi.org/10.1002/pbc.24420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045498PMC
June 2013

Safety in numbers: hyperdiploidy and prognosis.

Blood 2013 Mar;121(13):2374-6

New York University Cancer Institute.

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http://dx.doi.org/10.1182/blood-2013-02-480350DOI Listing
March 2013