Publications by authors named "William J Muller"

100Publications

Point-activated ESR1 has a dramatic effect on the development of sexually dimorphic organs.

Genes Dev 2020 Oct 10;34(19-20):1304-1309. Epub 2020 Sep 10.

Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.

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http://dx.doi.org/10.1101/gad.339424.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528702PMC
October 2020

In vivo modeling of the EGFR family in breast cancer progression and therapeutic approaches.

Adv Cancer Res 2020 16;147:189-228. Epub 2020 Jun 16.

Rosalind and Morris Goodman Cancer Research Center, McGill University, Montreal, QC, Canada; Department of Biochemistry, McGill University, Montreal, QC, Canada; Faculty of Medicine, McGill University, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/bs.acr.2020.04.004DOI Listing
September 2020

Benign course of SARS-CoV-2 infection in a series of pediatric oncology patients.

Pediatr Blood Cancer 2020 Jun 23:e28504. Epub 2020 Jun 23.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.28504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361248PMC
June 2020

SARS-CoV-2 Infection in Infants Less than 90 Days Old.

J Pediatr 2020 Sep 18;224:150-152. Epub 2020 Jun 18.

Division of Infectious Diseases, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago and Feinberg School of Medicine, Northwestern University, Chicago, IL.

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http://dx.doi.org/10.1016/j.jpeds.2020.06.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301101PMC
September 2020

Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR.

Cell Rep 2020 Apr;31(4):107571

Department of Biochemistry, McGill University, Montreal, QC H3A 1A3, Canada; Faculty of Medicine, McGill University, Montreal, QC H3A 1A3, Canada; Rosalind & Morris Goodman Cancer Centre, McGill University, Montreal, QC H3A 1A3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7281837PMC
April 2020

Utility of metagenomic next generation sequencing (mNGS) of plasma for infectious pathogens.

Clin Infect Dis 2020 Mar 4. Epub 2020 Mar 4.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1093/cid/ciaa218DOI Listing
March 2020

Varicella infection following vaccination in a pediatric kidney transplant recipient.

Pediatr Transplant 2020 06 18;24(4):e13667. Epub 2020 Feb 18.

Division of Infectious Diseases, Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Chicago, IL.

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http://dx.doi.org/10.1111/petr.13667DOI Listing
June 2020

Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer.

Cell Rep 2019 10;29(3):589-602.e6

Goodman Cancer Center, McGill University, Montreal, QC, Canada; Biochemistry Department, McGill University, Montreal, QC, Canada; Faculty of Medicine, McGill University, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.09.004DOI Listing
October 2019

Reduction of Global H3K27me Enhances HER2/ErbB2 Targeted Therapy.

Cell Rep 2019 10;29(2):249-257.e8

Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montréal, QC H3A 1A3, Canada; Department of Biochemistry, McGill University, Montréal, QC H3A 1A3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.105DOI Listing
October 2019

Noninvasive Diagnosis of Infection Using Plasma Next-Generation Sequencing: A Single-Center Experience.

Open Forum Infect Dis 2019 Aug;6(8)

Division of Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1093/ofid/ofz327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677669PMC
August 2019

Lessons about early neurodevelopment in children exposed to ZIKV in utero.

Nat Med 2019 08;25(8):1192-1193

Departments of Pediatrics and Neurology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

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http://dx.doi.org/10.1038/s41591-019-0540-1DOI Listing
August 2019

Risk factors for Clostridioides (Clostridium) difficile infection following solid organ transplantation in children.

Transpl Infect Dis 2019 Oct 5;21(5):e13149. Epub 2019 Aug 5.

Pediatric Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/tid.13149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800586PMC
October 2019

Cell-free DNA next-generation sequencing successfully detects infectious pathogens in pediatric oncology and hematopoietic stem cell transplant patients at risk for invasive fungal disease.

Pediatr Blood Cancer 2019 07 2;66(7):e27734. Epub 2019 Apr 2.

Division of Hematology, Oncology and Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.27734DOI Listing
July 2019

Laboratory Diagnosis of Neonatal Herpes Simplex Virus Infections.

J Clin Microbiol 2019 05 26;57(5). Epub 2019 Apr 26.

Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

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http://dx.doi.org/10.1128/JCM.01460-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498033PMC
May 2019

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

Cell Rep 2018 05;23(5):1476-1490

Montreal Clinical Research Institute (IRCM), Montréal, QC H2W 1R7, Canada; Molecular Biology Programs, Université de Montréal, Montréal, QC H3T 1J4, Canada; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, QC H3C 3J7, Canada; Department of Anatomy and Cell Biology, McGill University, Montréal, QC H3A 0C7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.019DOI Listing
May 2018

Pediatric Considerations for Postexposure Human Immunodeficiency Virus Prophylaxis.

Infect Dis Clin North Am 2018 03;32(1):91-101

Division of Pediatric Infectious Diseases, Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E. Chicago Avenue, Box 20, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.idc.2017.10.006DOI Listing
March 2018

In vivo evidence supporting a metastasis suppressor role for Stard13 (Dlc2) in ErbB2 (Neu) oncogene induced mouse mammary tumors.

Genes Chromosomes Cancer 2018 04 29;57(4):182-191. Epub 2017 Dec 29.

Research Institute of Oncology & Hematology, CancerCare Manitoba, Winnipeg, Manitoba, R3E 0V9, Canada.

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http://dx.doi.org/10.1002/gcc.22519DOI Listing
April 2018

Progressive polarity loss and luminal collapse disrupt tissue organization in carcinoma.

Genes Dev 2017 08 8;31(15):1573-1587. Epub 2017 Sep 8.

Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec H3A 1A3, Canada.

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http://dx.doi.org/10.1101/gad.300566.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630022PMC
August 2017

Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.

Breast Cancer Res 2017 Jun 30;19(1):74. Epub 2017 Jun 30.

Department of Cancer Biology, Vanderbilt University School of Medicine, 2220 Pierce Avenue, Rm 749 Preston Research Building, Nashville, TN, 37232, USA.

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http://dx.doi.org/10.1186/s13058-017-0868-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493112PMC
June 2017

Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1.

Nat Commun 2017 05 5;8:15289. Epub 2017 May 5.

Department of Integrative Oncology, BC Cancer Research Centre, BC Cancer Agency, Vancouver, British Columbia, Canada V5Z 1L3.

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http://dx.doi.org/10.1038/ncomms15289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424153PMC
May 2017

LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis.

Nat Commun 2017 04 24;8:15059. Epub 2017 Apr 24.

Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada H3A 1A3.

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http://dx.doi.org/10.1038/ncomms15059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413977PMC
April 2017

Mapping sites of herpes simplex virus type 1 glycoprotein D that permit insertions and impact gD and gB receptors usage.

Sci Rep 2017 03 3;7:43712. Epub 2017 Mar 3.

Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://www.nature.com/articles/srep43712
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http://dx.doi.org/10.1038/srep43712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334651PMC
March 2017

β-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model.

Proc Natl Acad Sci U S A 2017 01 17;114(5):E707-E716. Epub 2017 Jan 17.

Goodman Cancer Center, McGill University, Montreal, QC H3A 1A3, Canada;

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http://dx.doi.org/10.1073/pnas.1610383114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293039PMC
January 2017

The glucose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis.

Breast Cancer Res 2016 12 20;18(1):131. Epub 2016 Dec 20.

Department of Pathology, MS 8401, University of Colorado Anschutz Medical Campus, 12801 East 17th Avenue, Box 8104, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1186/s13058-016-0795-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168867PMC
December 2016

Preliminary Results From the US Zika Pregnancy Registry: Untangling Risks for Congenital Anomalies.

JAMA 2017 01;317(1):35-36

Department of Obstetrics-Gynecology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1001/jama.2016.18632DOI Listing
January 2017

Treatment of perinatal viral infections to improve neurologic outcomes.

Authors:
William J Muller

Pediatr Res 2017 01 27;81(1-2):162-169. Epub 2016 Sep 27.

Department of Pediatrics, Northwestern University Feinberg School of Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1038/pr.2016.191DOI Listing
January 2017

Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.

Cancer Res 2016 08 25;76(16):4752-64. Epub 2016 Apr 25.

Department of Cancer Biology, Vanderbilt University, Nashville, Tennessee. The Vanderbilt-Ingram Cancer Center at Vanderbilt University, Vanderbilt University, Nashville, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758362PMC
August 2016

The Type I Interferon Response Determines Differences in Choroid Plexus Susceptibility between Newborns and Adults in Herpes Simplex Virus Encephalitis.

mBio 2016 Apr 12;7(2):e00437-16. Epub 2016 Apr 12.

Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

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http://dx.doi.org/10.1128/mBio.00437-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959527PMC
April 2016

Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer.

Dis Model Mech 2016 Feb 31;9(2):131-40. Epub 2015 Dec 31.

Edinburgh Cancer Research UK Centre, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK

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http://dx.doi.org/10.1242/dmm.023143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770148PMC
February 2016

HSV targeting of the host phosphatase PP1α is required for disseminated disease in the neonate and contributes to pathogenesis in the brain.

Proc Natl Acad Sci U S A 2015 Dec 30;112(50):E6937-44. Epub 2015 Nov 30.

Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611;

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http://dx.doi.org/10.1073/pnas.1513045112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687582PMC
December 2015

Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition.

Mol Cell Biol 2015 Dec 21;35(23):4069-82. Epub 2015 Sep 21.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec, Canada Department of Medicine, McGill University, Montréal, Québec, Canada Department of Medicine, University of Montréal, Montréal, Québec, Canada

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http://dx.doi.org/10.1128/MCB.00741-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628068PMC
December 2015

Early viral suppression improves neurocognitive outcomes in HIV-infected children.

AIDS 2015 Jan;29(3):295-304

Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Washington and Seattle Children's Hospital, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332557PMC
January 2015

Loss of periostin/OSF-2 in ErbB2/Neu-driven tumors results in androgen receptor-positive molecular apocrine-like tumors with reduced Notch1 activity.

Breast Cancer Res 2015 Jan 16;17. Epub 2015 Jan 16.

Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.

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http://dx.doi.org/10.1186/s13058-014-0513-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355979PMC
January 2015

Differential reliance on autophagy for protection from HSV encephalitis between newborns and adults.

PLoS Pathog 2015 Jan 8;11(1):e1004580. Epub 2015 Jan 8.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287605PMC
January 2015

ERBB2 deficiency alters an E2F-1-dependent adaptive stress response and leads to cardiac dysfunction.

Mol Cell Biol 2014 Dec 22;34(23):4232-43. Epub 2014 Sep 22.

Goodman Cancer Research Centre, McGill University, Montréal, Quebec, Canada Department of Biochemistry, McGill University, Montréal, Quebec, Canada Department of Medicine and Oncology, McGill University, Montréal, Quebec, Canada

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http://dx.doi.org/10.1128/MCB.00895-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248744PMC
December 2014

Herpes simplex virus serotype and entry receptor availability alter CNS disease in a mouse model of neonatal HSV.

Pediatr Res 2014 Dec 8;76(6):528-34. Epub 2014 Sep 8.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1038/pr.2014.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233006PMC
December 2014

Deletion of Cd151 reduces mammary tumorigenesis in the MMTV/PyMT mouse model.

BMC Cancer 2014 Jul 11;14:509. Epub 2014 Jul 11.

School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, Priority Research Centre in Cancer, University of Newcastle, Newcastle, NSW, Australia.

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http://link.springer.com/content/pdf/10.1186%2F1471-2407-14-
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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-14-509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226978PMC
July 2014

Herpesvirus entry mediator (HVEM) attenuates signals mediated by the lymphotoxin β receptor (LTβR) in human cells stimulated by the shared ligand LIGHT.

Mol Immunol 2014 Nov 28;62(1):96-103. Epub 2014 Jun 28.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Northwestern University, 310 East Superior Street, Morton 4-685, Chicago, IL 60611 USA. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2014.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157106PMC
November 2014

Mammary tumour development is dose-dependently inhibited by n-3 polyunsaturated fatty acids in the MMTV-neu(ndl)-YD5 transgenic mouse model.

Lipids Health Dis 2014 Jun 11;13:96. Epub 2014 Jun 11.

Department of Human Health and Nutritional Sciences, University of Guelph, Animal Science/Nutrition Building, Room 342, 491 Gordon Street, N1G 2W1 Guelph, ON, Canada.

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http://dx.doi.org/10.1186/1476-511X-13-96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064525PMC
June 2014

Neurologic disease in HIV-infected children and the impact of combination antiretroviral therapy.

Rev Med Virol 2014 Sep 8;24(5):316-31. Epub 2014 May 8.

Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.1002/rmv.1793DOI Listing
September 2014

Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors.

Cell Res 2014 May 28;24(5):542-59. Epub 2014 Mar 28.

1] Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA [2] Cancer Biology Program, Graduate School of Biomedical Sciences-Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/cr.2014.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011340PMC
May 2014

Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase.

Nat Commun 2013 ;4:2976

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada V5Z 1L3.

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http://dx.doi.org/10.1038/ncomms3976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905719PMC
July 2014

Transgenic mouse models--a seminal breakthrough in oncogene research.

Cold Spring Harb Protoc 2013 Dec 1;2013(12):1099-108. Epub 2013 Dec 1.

Department of Biochemistry and Goodman Cancer Research Center, McGill University, Montreal, Quebec H3A 1A3, Canada.

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http://dx.doi.org/10.1101/pdb.top069765DOI Listing
December 2013

Dasatinib inhibits mammary tumour development in a genetically engineered mouse model.

J Pathol 2013 Aug;230(4):430-40

Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1002/path.4202DOI Listing
August 2013

The immunologic basis for severe neonatal herpes disease and potential strategies for therapeutic intervention.

Clin Dev Immunol 2013 31;2013:369172. Epub 2013 Mar 31.

Department of Pediatrics, Division of Infectious Diseases, University of Washington and Seattle Children's Hospital, Seattle, WA 98105, USA.

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http://dx.doi.org/10.1155/2013/369172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626239PMC
July 2013

BIM, PUMA, and the achilles' heel of oncogene addiction.

Sci Signal 2013 Mar 26;6(268):pe12. Epub 2013 Mar 26.

Department of Biochemistry and Goodman Cancer Research Center, McGill University, Montreal, Quebec H3G 2J7, Canada.

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http://dx.doi.org/10.1126/scisignal.2004113DOI Listing
March 2013

Bcl3 selectively promotes metastasis of ERBB2-driven mammary tumors.

Cancer Res 2013 Jan 13;73(2):745-55. Epub 2012 Nov 13.

University of Cardiff School of Biosciences, Museum Avenue, Cardiff, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1321DOI Listing
January 2013

Pathogenesis of neonatal herpes simplex 2 disease in a mouse model is dependent on entry receptor expression and route of inoculation.

J Virol 2013 Jan 24;87(1):474-81. Epub 2012 Oct 24.

Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1128/JVI.01849-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536411PMC
January 2013

Mammary tumor development is directly inhibited by lifelong n-3 polyunsaturated fatty acids.

J Nutr Biochem 2013 Jan 29;24(1):388-95. Epub 2012 Sep 29.

Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, Canada.

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http://dx.doi.org/10.1016/j.jnutbio.2012.08.002DOI Listing
January 2013

Focal adhesion kinase is required for β-catenin-induced mobilization of epidermal stem cells.

Carcinogenesis 2012 Dec 12;33(12):2369-76. Epub 2012 Sep 12.

The Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1093/carcin/bgs284DOI Listing
December 2012

Mammary epithelial-restricted expression of activated c-src rescues the block to mammary gland morphogenesis due to the deletion of the C-terminus of Patched-1.

Dev Biol 2012 Oct 9;370(2):187-97. Epub 2012 Aug 9.

Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S001216061200411
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http://dx.doi.org/10.1016/j.ydbio.2012.07.027DOI Listing
October 2012

Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer.

Cancer Res 2012 Sep 6;72(17):4417-28. Epub 2012 Jul 6.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1339-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556997PMC
September 2012

Herpes simplex virus-2 glycoprotein interaction with HVEM influences virus-specific recall cellular responses at the mucosa.

Clin Dev Immunol 2012 14;2012:284104. Epub 2012 May 14.

Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1155/2012/284104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359786PMC
September 2012

An interaction map of endoplasmic reticulum chaperones and foldases.

Mol Cell Proteomics 2012 Sep 4;11(9):710-23. Epub 2012 Jun 4.

Department of Biochemistry, McGill University, Montréal, Québec H3G 1Y6, Canada.

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http://dx.doi.org/10.1074/mcp.M111.016550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434782PMC
September 2012

Uncoupling of PI3K from ErbB3 impairs mammary gland development but does not impact on ErbB2-induced mammary tumorigenesis.

Cancer Res 2012 Jun 4;72(12):3080-90. Epub 2012 Jun 4.

Goodman Cancer Centre, Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3513DOI Listing
June 2012

Loss of the 14-3-3σ tumor suppressor is a critical event in ErbB2-mediated tumor progression.

Cancer Discov 2012 Jan 29;2(1):68-81. Epub 2011 Nov 29.

Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0189DOI Listing
January 2012

Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis.

Carcinogenesis 2012 Jun 20;33(6):1225-30. Epub 2012 Mar 20.

Transgenic Oncogenesis and Genomics Section, Laboratory of Cancer Biology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/carcin/bgs129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514862PMC
June 2012

Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo.

Breast Cancer Res 2012 Feb 28;14(1):R36. Epub 2012 Feb 28.

Goodman Cancer Centre, McGill University, 1160 Pine Ave, west, Montreal, QC, H3A 1A3, Canada.

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http://dx.doi.org/10.1186/bcr3131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496154PMC
February 2012

Contribution of CXCL12 secretion to invasion of breast cancer cells.

Breast Cancer Res 2012 Feb 7;14(1):R23. Epub 2012 Feb 7.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1301 Morris Park Ave, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1186/bcr3108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496141PMC
February 2012

PGC-1α promotes the growth of ErbB2/Neu-induced mammary tumors by regulating nutrient supply.

Cancer Res 2012 Mar 19;72(6):1538-46. Epub 2012 Jan 19.

Department of Biochemistry and Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.

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http://cancerres.aacrjournals.org/content/canres/early/2012/
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-11-2967DOI Listing
March 2012

β1-integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer.

Breast Cancer Res 2011 30;13(6):229. Epub 2011 Nov 30.

Goodman Cancer Centre, McGill University, 1160 Pine Avenue West, Montreal, Québec, Canada.

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http://dx.doi.org/10.1186/bcr2905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326542PMC
June 2012

PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target.

J Clin Invest 2011 Dec 7;121(12):4655-69. Epub 2011 Nov 7.

Department of Medicine, McGill University Health Centre, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1172/JCI46134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225988PMC
December 2011

Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway.

Sci Signal 2011 Sep;4(192):ra62

Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, Montreal, Quebec H3T1E2, Canada.

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http://dx.doi.org/10.1126/scisignal.2001630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752779PMC
September 2011