Publications






Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.
Cell Stem Cell 2017 Sep 10;21(3):305-318.e8. Epub 2017 Aug 10.
Center for Psychiatric Genetics, NorthShore University HealthSystem, Evanston, IL 60201, USA; Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL 60637, USA. Electronic address:

Chromatin Accessibility Landscape of Cutaneous T Cell Lymphoma and Dynamic Response to HDAC Inhibitors.
Cancer Cell 2017 Jul 15;32(1):27-41.e4. Epub 2017 Jun 15.
Center for Personal Dynamic Regulomes and Program in Epithelial Biology, Stanford University School of Medicine, CCSR 2155c, 269 Campus Drive, Stanford, CA 94305-5168, USA; Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

Epigenomics of human CD8 T cell differentiation and aging.
Sci Immunol 2017 Feb 17;2(8). Epub 2017 Feb 17.
Division of Immunology and Rheumatology, Department of Medicine, Stanford University, Stanford, CA 94305; and Department of Medicine, Veterans Affairs Palo Alto Health Care, System, Palo Alto, CA 94306.


Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.
Cell 2016 Jul 30;166(2):328-342. Epub 2016 Jun 30.
Cancer Biology Program, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions.
Genome Res 2015 Nov 27;25(11):1757-70. Epub 2015 Aug 27.
Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA; Department of Applied Physics, Stanford University, Stanford, California 94305, USA.

Single-cell chromatin accessibility reveals principles of regulatory variation.
Nature 2015 Jul 17;523(7561):486-90. Epub 2015 Jun 17.
1] Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA [2] Department of Applied Physics, Stanford University, Stanford, California 94025, USA.


A conditional system to specifically link disruption of protein-coding function with reporter expression in mice.
Cell Rep 2014 Jun 12;7(6):2078-86. Epub 2014 Jun 12.
Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA; Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305-5324, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305-5456, USA. Electronic address:

A pause sequence enriched at translation start sites drives transcription dynamics in vivo.
Science 2014 May 1;344(6187):1042-7. Epub 2014 May 1.
Department of Cellular and Molecular Pharmacology, Howard Hughes Medical Institute, California Institute for Quantitative Biosciences, Center for RNA Systems Biology, University of California, San Francisco, San Francisco, CA 94158, USA.

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position.
Nat Methods 2013 Dec 6;10(12):1213-8. Epub 2013 Oct 6.
1] Department of Genetics, Stanford University School of Medicine, Stanford, California, USA. [2] Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California, USA. [3] Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California, USA.




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