William E Smoyer

William E Smoyer

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William E Smoyer

William E Smoyer

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Dyslipidemia and cardiovascular health in childhood nephrotic syndrome.

Pediatr Nephrol 2019 Jul 13. Epub 2019 Jul 13.

Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s00467-019-04301-yDOI Listing
July 2019

Rituximab Use in the Management of Childhood Nephrotic Syndrome.

Front Pediatr 2019 10;7:178. Epub 2019 May 10.

Division of Nephrology, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, United States.

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http://dx.doi.org/10.3389/fped.2019.00178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524616PMC
May 2019

"Learn From Every Patient": How a Learning Health System Can Improve Patient Care.

Pediatr Qual Saf 2018 Sep-Oct;3(5):e100. Epub 2018 Sep 5.

Department of Pediatrics, Nationwide Children's Hospital, Columbus, Dayton, Ohio.

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http://dx.doi.org/10.1097/pq9.0000000000000100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221586PMC
September 2018

Pharmacological and genetic inhibition of downstream targets of p38 MAPK in experimental nephrotic syndrome.

Am J Physiol Renal Physiol 2018 04 29;314(4):F602-F613. Epub 2017 Nov 29.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital , Columbus, Ohio.

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http://www.physiology.org/doi/10.1152/ajprenal.00207.2017
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http://dx.doi.org/10.1152/ajprenal.00207.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966757PMC
April 2018

Dyslipidaemia in nephrotic syndrome: mechanisms and treatment.

Nat Rev Nephrol 2018 Jan 27;14(1):57-70. Epub 2017 Nov 27.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, and Department of Pediatrics, The Ohio State University, 700 Children's Drive, W303, Columbus, Ohio 43205, USA.

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http://dx.doi.org/10.1038/nrneph.2017.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770189PMC
January 2018

Thrombin-Induced Podocyte Injury Is Protease-Activated Receptor Dependent.

J Am Soc Nephrol 2017 Sep 19;28(9):2618-2630. Epub 2017 Apr 19.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital,

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http://dx.doi.org/10.1681/ASN.2016070789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576925PMC
September 2017

Role of albumin and its modifications in glomerular injury.

Pflugers Arch 2017 Aug 22;469(7-8):975-982. Epub 2017 Jul 22.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA.

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http://dx.doi.org/10.1007/s00424-017-2029-4DOI Listing
August 2017

'Learn From Every Patient': implementation and early results of a learning health system.

Dev Med Child Neurol 2017 Feb 22;59(2):183-191. Epub 2016 Aug 22.

Nationwide Children's Hospital, Columbus, OH, USA.

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http://dx.doi.org/10.1111/dmcn.13227DOI Listing
February 2017

Glomerular Diseases: Registries and Clinical Trials.

Clin J Am Soc Nephrol 2016 12 26;11(12):2234-2243. Epub 2016 Sep 26.

Due to the number of contributing authors, the affiliations are provided in the Supplemental Material.

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http://dx.doi.org/10.2215/CJN.00540116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142054PMC
December 2016

Creating Local Learning Health Systems: Think Globally, Act Locally.

JAMA 2016 Dec;316(23):2481-2482

The Ohio State University, Columbus.

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http://dx.doi.org/10.1001/jama.2016.16459DOI Listing
December 2016

"Saving Young Lives" with acute kidney injury: the challenge of acute dialysis in low-resource settings.

Kidney Int 2016 Feb;89(2):254-6

International Society of Nephrology, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2015.10.009DOI Listing
February 2016

Disease Severity Correlates with Thrombotic Capacity in Experimental Nephrotic Syndrome.

J Am Soc Nephrol 2015 Dec 8;26(12):3009-19. Epub 2015 Apr 8.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's, Columbus, Ohio; Nephrology, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio; and.

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http://dx.doi.org/10.1681/ASN.2014111097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657841PMC
December 2015

Saving Young Lives: provision of acute dialysis in low-resource settings.

Lancet 2015 Nov 20;386(10008):2056. Epub 2015 Nov 20.

University Hospitals of Leicester, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1016/S0140-6736(15)00971-XDOI Listing
November 2015

Peritoneal dialysis, acute kidney injury, and the Saving Young Lives program.

Perit Dial Int 2014 Jul-Aug;34(5):478-80

Yale University New Haven, CT, USA Ohio State University Columbus, Ohio, USA Renal Research Institute New York, NY, USA International Society of Nephrology Brussels, Belgium University of Leicester Leicester, UK.

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http://dx.doi.org/10.3747/pdi.2014.00041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114665PMC
May 2015

Healthcare burden of venous thromboembolism in childhood chronic renal diseases.

Pediatr Nephrol 2015 May 7;30(5):829-37. Epub 2014 Dec 7.

Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA,

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http://dx.doi.org/10.1007/s00467-014-3008-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375065PMC
May 2015

Development of a pediatric-specific clinical probability tool for diagnosis of venous thromboembolism: a feasibility study.

Pediatr Res 2015 Mar 17;77(3):463-71. Epub 2014 Dec 17.

1] Division of Hem/Onc/BMT, Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio [2] Center for Innovation in Pediatric Practice, The Research Institute at Nationwide Children's, Columbus, Ohio.

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http://dx.doi.org/10.1038/pr.2014.198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346381PMC
March 2015

Albumin-induced podocyte injury and protection are associated with regulation of COX-2.

Kidney Int 2014 Dec 11;86(6):1150-60. Epub 2014 Jun 11.

1] Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA [2] Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/ki.2014.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245399PMC
December 2014

Hemodialysis for near-fatal sodium phosphate toxicity in a child receiving sodium phosphate enemas.

Pediatr Emerg Care 2014 Nov;30(11):814-7

From the *Nephrology Section, †Center for Clinical and Translational Research, The Research Institute, and ‡Critical Care Section, Nationwide Children's Hospital, Columbus, OH.

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http://dx.doi.org/10.1097/PEC.0000000000000267DOI Listing
November 2014

Venous thromboembolism in pediatric nephrotic syndrome.

Pediatr Nephrol 2014 Jun 28;29(6):989-97. Epub 2013 Jun 28.

Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA,

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http://dx.doi.org/10.1007/s00467-013-2525-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556227PMC
June 2014

Meeting the demand for pediatric clinical trials.

Sci Transl Med 2014 Mar;6(227):227fs11

Department of Pediatrics and Clinical and Translational Science Institute, Children's National Medical Center; and School of Medicine and Health Sciences, George Washington University, Washington, DC 20010, USA.

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http://dx.doi.org/10.1126/scitranslmed.3008043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104358PMC
March 2014

The CTSA mentored career development program: supporting the careers of child health investigators.

Clin Transl Sci 2014 Feb 8;7(1):44-7. Epub 2013 Nov 8.

Utah Center for Clinical and Translational Science and the Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1111/cts.12122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929228PMC
February 2014

Treatment outcome of late steroid-resistant nephrotic syndrome: a study by the Midwest Pediatric Nephrology Consortium.

Pediatr Nephrol 2013 Aug 30;28(8):1235-41. Epub 2013 Apr 30.

Department of Pediatrics, Louisiana State University Health Sciences Center, 200 Henry Clay Avenue, New Orleans, LA 70118, USA.

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http://dx.doi.org/10.1007/s00467-013-2483-yDOI Listing
August 2013

Nephrotic syndrome: Genetic screening in steroid-resistant nephrotic syndrome.

Nat Rev Nephrol 2013 Jul 21;9(7):379-81. Epub 2013 May 21.

Division of Pediatric Nephrology, Rady Children's Hospital, University of California, San Diego, 9500 Gilman Drive, MC 0634, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1038/nrneph.2013.101DOI Listing
July 2013

Genetic testing in nephrotic syndrome--challenges and opportunities.

Nat Rev Nephrol 2013 03 15;9(3):179-84. Epub 2013 Jan 15.

Department of Pediatrics and Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1038/nrneph.2012.286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702380PMC
March 2013

Trends in pediatric primary membranoproliferative glomerulonephritis costs and complications.

Pediatr Nephrol 2012 Dec 18;27(12):2243-50. Epub 2012 Jul 18.

Department of Pediatrics, Division of Nephrology, China Medical University Hospital, Taichung, Taiwan.

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http://dx.doi.org/10.1007/s00467-012-2249-yDOI Listing
December 2012

A new 'tac' for childhood nephrotic syndrome.

Kidney Int 2012 Nov;82(10):1049-51

Section of Nephrology, Nationwide Children's Hospital, Columbus, Ohio, USA.

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http://dx.doi.org/10.1038/ki.2012.272DOI Listing
November 2012

Trends in hospitalization characteristics for pediatric nephrotic syndrome in the USA.

Clin Nephrol 2012 Aug;78(2):106-11

Center for Clinical and Translational Research, Nationwide Children's Hospital, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.5414/cn107303DOI Listing
August 2012

Childhood nephrotic syndrome--current and future therapies.

Nat Rev Nephrol 2012 Jun 12;8(8):445-58. Epub 2012 Jun 12.

Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/nrneph.2012.115DOI Listing
June 2012

Epidemiology and pathophysiology of nephrotic syndrome-associated thromboembolic disease.

Clin J Am Soc Nephrol 2012 Mar 16;7(3):513-20. Epub 2012 Feb 16.

Department of Pediatrics, The Ohio State University College of Medicine, Columbus, USA.

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http://dx.doi.org/10.2215/CJN.10131011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3302669PMC
March 2012

Inhibition of the protein kinase MK-2 protects podocytes from nephrotic syndrome-related injury.

Am J Physiol Renal Physiol 2011 Sep 25;301(3):F509-19. Epub 2011 May 25.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH 43205, USA.

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http://dx.doi.org/10.1152/ajprenal.00661.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174552PMC
September 2011

Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects.

Mol Pharmacol 2011 Sep 2;80(3):389-99. Epub 2011 Jun 2.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.

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http://dx.doi.org/10.1124/mol.111.071654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164328PMC
September 2011

Do declining private insurance coverage rates influence pediatric hospital charging practices?

Clin Pediatr (Phila) 2011 May 27;50(5):417-23. Epub 2011 Feb 27.

The Research Institute at Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.

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http://dx.doi.org/10.1177/0009922810393498DOI Listing
May 2011

Dose- and time-dependent glucocorticoid receptor signaling in podocytes.

Am J Physiol Renal Physiol 2010 Oct 14;299(4):F845-53. Epub 2010 Jul 14.

Center for Clinical and Translational Research, The Research Institute at Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH 43205, USA.

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http://ajprenal.physiology.org/content/ajprenal/299/4/F845.f
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http://ajprenal.physiology.org/cgi/doi/10.1152/ajprenal.0016
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http://dx.doi.org/10.1152/ajprenal.00161.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957255PMC
October 2010

Management patterns of childhood-onset nephrotic syndrome.

Pediatr Nephrol 2009 Nov 12;24(11):2193-201. Epub 2009 Aug 12.

University of North Carolina at Chapel Hill, 27599-7155, USA.

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http://dx.doi.org/10.1007/s00467-009-1282-yDOI Listing
November 2009

Management of childhood onset nephrotic syndrome.

Pediatrics 2009 Aug 27;124(2):747-57. Epub 2009 Jul 27.

Division of Nephrology and Hypertension, Department ofMedicine and Pediatrics, University of North Carolina, ChapelHill, North Carolina 27599-7155, USA.

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http://pediatrics.aappublications.org/content/pediatrics/124
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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2008-1559DOI Listing
August 2009

Antihypertensive prescription in pediatric dialysis: a practitioner survey by the Midwest Pediatric Nephrology Consortium study.

Hemodial Int 2009 Jul 15;13(3):307-15. Epub 2009 Jul 15.

Department of Pediatrics, Wake Forest University, Winston-Salem, North Carolina 27157, USA.

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http://doi.wiley.com/10.1111/j.1542-4758.2009.00392.x
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http://dx.doi.org/10.1111/j.1542-4758.2009.00392.xDOI Listing
July 2009

Significance of hemolysis on extracorporeal life support after cardiac surgery in children.

Pediatr Nephrol 2009 Mar 12;24(3):589-95. Epub 2008 Nov 12.

Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1007/s00467-008-1047-zDOI Listing
March 2009

Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis.

Nephrol Dial Transplant 2009 Jan 22;24(1):231-8. Epub 2008 Aug 22.

1Department of Pharmacy Practice, University of Toledo College of Pharmacy, Toledo, OH 43606-3360, USA.

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http://dx.doi.org/10.1093/ndt/gfn467DOI Listing
January 2009

Arterial compliance in adolescents and young adults receiving chronic hemodialysis.

Ren Fail 2008 ;30(6):591-6

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27157, USA.

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http://dx.doi.org/10.1080/08860220802132064DOI Listing
November 2008

Clinical presentation and outcome in a cohort of paediatric patients with membranous lupus nephritis.

Nephrol Dial Transplant 2007 Dec 29;22(12):3495-500. Epub 2007 Jul 29.

Pediatric Nephrology, Pediatric and Adolescent Medicine Department, Mayo Clinic, Rochester, MN 55095, USA.

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http://ndt.oxfordjournals.org/content/22/12/3495.full.pdf
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http://ndt.oxfordjournals.org/cgi/doi/10.1093/ndt/gfm491
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http://dx.doi.org/10.1093/ndt/gfm491DOI Listing
December 2007

Enhanced hemolysis in pediatric patients requiring extracorporeal membrane oxygenation and continuous renal replacement therapy.

Ann Thorac Cardiovasc Surg 2007 Dec;13(6):378-83

Department of Pediatrics and Communicable Diseases University of Michigan, Ann Arbor, MI, USA.

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December 2007

Single and combination toxic metal exposures induce apoptosis in cultured murine podocytes exclusively via the extrinsic caspase 8 pathway.

Toxicol Sci 2006 Apr 18;90(2):392-9. Epub 2006 Jan 18.

Pediatric Nephrology Division, C. S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1093/toxsci/kfj106DOI Listing
April 2006

Reduction in podocyte density as a pathologic feature in early diabetic nephropathy in rodents: prevention by lipoic acid treatment.

BMC Nephrol 2006 Mar 15;7. Epub 2006 Mar 15.

Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109-0676, USA.

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http://dx.doi.org/10.1186/1471-2369-7-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435876PMC
March 2006

Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization.

Kidney Int 2005 Dec;68(6):2473-83

Pediatric Nephrology Division, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00723.xDOI Listing
December 2005

p38 MAPK/HSP25 signaling mediates cadmium-induced contraction of mesangial cells and renal glomeruli.

Am J Physiol Renal Physiol 2005 Jun 1;288(6):F1133-43. Epub 2005 Feb 1.

Dept. of Cell and Developmental Biology, Univ. of Michigan Medical School, 1335 Catherine St., Ann Arbor, MI 48109-0616, USA.

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http://ajprenal.physiology.org/content/ajprenal/288/6/F1133.
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http://ajprenal.physiology.org/cgi/doi/10.1152/ajprenal.0021
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http://dx.doi.org/10.1152/ajprenal.00210.2004DOI Listing
June 2005

Differential proteomic analysis of proteins induced by glucocorticoids in cultured murine podocytes.

Kidney Int 2005 Apr;67(4):1275-85

Pediatric Nephrology Division, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00205.xDOI Listing
April 2005

Differential induction of podocyte heat shock proteins by prolonged single and combination toxic metal exposure.

Toxicol Sci 2005 Mar 8;84(1):120-8. Epub 2004 Dec 8.

Pediatric Nephrology Division, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1093/toxsci/kfi048DOI Listing
March 2005

Induction of antioxidant enzymes in murine podocytes precedes injury by puromycin aminonucleoside.

Kidney Int 2004 Nov;66(5):1881-9

Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2004.00962.xDOI Listing
November 2004

Recent advances in congenital nephrotic syndrome.

Curr Opin Pediatr 2004 Apr;16(2):165-70

Pediatric Nephrology Division, University of Michigan Health System, Ann Arbor, Michigan 48109-064622, USA.

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http://dx.doi.org/10.1097/00008480-200404000-00009DOI Listing
April 2004

Clearance of amino acids by hemodialysis in argininosuccinate synthetase deficiency.

J Pediatr 2004 Apr;144(4):536-40

Department of Nephrology, Children's National Medical Center, George Washington University, 111 Michigan Avenue NW, Washington, DC 20010, USA.

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http://ac.els-cdn.com/S0022347604000782/1-s2.0-S002234760400
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http://linkinghub.elsevier.com/retrieve/pii/S002234760400078
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http://dx.doi.org/10.1016/j.jpeds.2004.01.037DOI Listing
April 2004

Use of mycophenolate mofetil in steroid-dependent and -resistant nephrotic syndrome.

Pediatr Nephrol 2003 Aug 28;18(8):833-7. Epub 2003 May 28.

University of Michigan Health Sciences Center, Mott Children's Hospital, 1505 Simpson Road East, F6865/Box 0297, Ann Arbor, MI 48109-0297, USA.

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http://dx.doi.org/10.1007/s00467-003-1175-4DOI Listing
August 2003

Hsp27 regulates podocyte cytoskeletal changes in an in vitro model of podocyte process retraction.

FASEB J 2002 Mar;16(3):315-26

Pediatric Nephrology Division, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1096/fj.01-0681comDOI Listing
March 2002