Publications by authors named "William E Farrell"

37Publications

DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis.

Epigenomics 2017 04 25;9(4):419-428. Epub 2016 Nov 25.

Guy Hilton Research Centre, Institute for Applied Clinical Sciences, Keele University, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, UK.

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April 2017

Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies.

Epigenetics 2018 25;13(2):122-128. Epub 2018 Jan 25.

a Institute for Science and Technology in Medicine , Keele University, Guy Hilton Research Center , Staffordshire , UK.

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December 2018

The BH3 Mimetic Obatoclax Accumulates in Lysosomes and Causes Their Alkalinization.

PLoS One 2016 7;11(3):e0150696. Epub 2016 Mar 7.

Institute for Science and Technology in Medicine, Keele University, Stoke-on-Trent, Staffordshire, United Kingdom.

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August 2016

Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes.

Epigenomics 2016 Feb 10;8(2):209-24. Epub 2015 Nov 10.

Institute for Science & Technology in Medicine, Keele University, Guy Hilton Research Centre, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, UK.

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February 2016

DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS.

Epigenomics 2015 ;7(4):539-51

Institute for Science & Technology in Medicine, Keele University, Guy Hilton Research Centre, Thornburrow Drive, Hartshill, Stoke-on-Trent, Staffordshire, ST4 7QB, UK.

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June 2016

Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells.

Pituitary 2015 Oct;18(5):674-84

Human Disease and Genomics Group, Institute of Science and Technology in Medicine, School of Medicine, Keele University, Stoke-on-Trent, Staffordshire, ST4 7QB, UK.

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October 2015

Methylation of the FGFR2 gene is associated with high birth weight centile in humans.

Epigenomics 2014 ;6(5):477-91

Institute of Science & Technology in Medicine, Keele University School of Medicine, University Hospital of North Staffordshire, Stoke-on-Trent, Staffordshire, UK.

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July 2015

Epigenetics of pituitary tumours: an update.

Curr Opin Endocrinol Diabetes Obes 2014 Aug;21(4):299-305

Human Disease and Genomics Group, Institute of Science and Technology in Medicine, School of Medicine, Keele University, Stoke on Trent, Staffordshire, UK.

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August 2014

The EFEMP1 gene: a frequent target for epigenetic silencing in multiple human pituitary adenoma subtypes.

Neuroendocrinology 2013 6;98(3):200-11. Epub 2013 Nov 6.

Institute of Science and Technology in Medicine, Keele University School of Medicine, Stoke-on-Trent, UK.

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August 2014

Preincubation of pituitary tumor cells with the epidrugs zebularine and trichostatin A are permissive for retinoic acid-augmented expression of the BMP-4 and D2R genes.

Endocrinology 2013 May 28;154(5):1711-21. Epub 2013 Mar 28.

Institute of Science and Technology in Medicine, Keele University School of Medicine, Stoke-on-Trent ST4 7QB, United Kingdom.

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May 2013

Quantitative, genome-wide analysis of the DNA methylome in sporadic pituitary adenomas.

Endocr Relat Cancer 2012 Dec 19;19(6):805-16. Epub 2012 Nov 19.

Institute of Science and Technology in Medicine, Keele University School of Medicine, Stoke-on-Trent, Staffordshire ST4 7QB, UK.

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December 2012

Antiepileptic drugs and the fetal epigenome.

Epilepsia 2013 Jan 27;54(1):e16-9. Epub 2012 Sep 27.

School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Leicestershire, United Kingdom.

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January 2013