Publications by authors named "William Dougall"

68 Publications

Dual targeting of RANKL and PD-1 with a bispecific antibody improves anti-tumor immunity.

Clin Transl Immunology 2019 27;8(10):e01081. Epub 2019 Sep 27.

Immunology in Cancer and Infection Laboratory QIMR Berghofer Medical Research Institute Herston Qld Australia.

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September 2019

An observational study of concomitant immunotherapies and denosumab in patients with advanced melanoma or lung cancer.

Oncoimmunology 2018;7(12):e1480301. Epub 2018 Sep 5.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.

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September 2018

Roles of the RANKL-RANK axis in antitumour immunity - implications for therapy.

Nat Rev Clin Oncol 2018 11;15(11):676-693

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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November 2018

Receptor activator of NF-κB (RANK)-mediated induction of metastatic spread and association with poor prognosis in renal cell carcinoma.

Urol Oncol 2018 11 28;36(11):502.e15-502.e24. Epub 2018 Aug 28.

Department of Urology, University Medicine at the Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany; Institute of Urologic Oncology, Department of Urology, David Geffen School of Medicine at the University of California, Los Angeles, CA; Institute of Medical Biochemistry and Molecular Medicine, University Medicine at the Ernst-Moritz-Arndt University Greifswald, Greifswald, Germany. Electronic address:

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November 2018

RANKL blockade improves efficacy of PD1-PD-L1 blockade or dual PD1-PD-L1 and CTLA4 blockade in mouse models of cancer.

Oncoimmunology 2018;7(6):e1431088. Epub 2018 Feb 14.

Department of Immunology, Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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February 2018

CD96 targeted antibodies need not block CD96-CD155 interactions to promote NK cell anti-metastatic activity.

Oncoimmunology 2018;7(5):e1424677. Epub 2018 Feb 1.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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February 2018

Co-administration of RANKL and CTLA4 Antibodies Enhances Lymphocyte-Mediated Antitumor Immunity in Mice.

Clin Cancer Res 2017 Oct 20;23(19):5789-5801. Epub 2017 Jun 20.

Immunology in Cancer and Infection, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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October 2017

TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.

Immunol Rev 2017 03;276(1):112-120

Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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March 2017

Distribution of RANK and RANK Ligand in Normal Human Tissues as Determined by an Optimized Immunohistochemical Method.

Appl Immunohistochem Mol Morphol 2017 May/Jun;25(5):299-307

*Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles ‡Dako, an Agilent technologies company, Carpinteria ∥Department of Comparative Biology and Safety Sciences ¶Formerly Department of Pathology, Amgen Inc., Thousand Oaks, CA †Formerly Department of Pathology §Department of Oncology Research, Amgen Inc., Seattle WA.

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November 2017

Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy.

Clin Cancer Res 2016 Nov 12;22(21):5183-5188. Epub 2016 Sep 12.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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November 2016

RANK and RANK ligand expression in primary human osteosarcoma.

J Bone Oncol 2015 Sep 29;4(3):59-68. Epub 2015 Jul 29.

Therapeutic Innovation Unit, Amgen Inc., Seattle, WA, USA.

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September 2015

Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors.

PLoS One 2015 10;10(6):e0128467. Epub 2015 Jun 10.

Department of Molecular Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, United States of America.

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March 2016

RANKL expression in normal and malignant breast tissue responds to progesterone and is up-regulated during the luteal phase.

Breast Cancer Res Treat 2014 Aug 10;146(3):515-23. Epub 2014 Jul 10.

Department of Surgery, Northwestern University Feinberg School of Medicine, 303 E. Superior Street Lurie 4-111, Chicago, IL, 60611, USA.

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August 2014