Publications by authors named "William Clay Brown"

10Publications

Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.

ACS Med Chem Lett 2016 Dec 13;7(12):1092-1096. Epub 2016 Sep 13.

Departments of Internal Medicine and Biological Chemistry and Life Sciences Institute, University of Michigan , Ann Arbor, Michigan 48109, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acsmedchemlett.6b00299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5151139PMC
December 2016

DHX9/RHA Binding to the PBS-Segment of the Genomic RNA during HIV-1 Assembly Bolsters Virion Infectivity.

J Mol Biol 2016 06 21;428(11):2418-2429. Epub 2016 Apr 21.

Department of Biochemistry, University of Missouri, Columbia, MO 65211, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2016.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884555PMC
June 2016

Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain.

PLoS One 2016 6;11(1):e0146522. Epub 2016 Jan 6.

Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146522PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703388PMC
July 2016

Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.

J Biol Chem 2015 Feb 7;290(9):5226-39. Epub 2015 Jan 7.

From the Department of Biological Chemistry, Life Sciences Institute, Center for Structural Biology, University of Michigan, Ann Arbor, Michigan 48109 and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M114.626382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342443PMC
February 2015

Structure and activity of DmmA, a marine haloalkane dehalogenase.

Protein Sci 2012 Feb 4;21(2):239-48. Epub 2012 Jan 4.

Life Sciences Institute, University of Michigan, 210 Washtenaw Ave., Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pro.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324768PMC
February 2012

New ligation-independent cloning vectors compatible with a high-throughput platform for parallel construct expression evaluation using baculovirus-infected insect cells.

Protein Expr Purif 2011 May 22;77(1):34-45. Epub 2011 Jan 22.

High-throughput Protein Lab, Center for Structural Biology, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pep.2011.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051273PMC
May 2011

Modes of calreticulin recruitment to the major histocompatibility complex class I assembly pathway.

J Biol Chem 2010 Feb 3;285(7):4520-35. Epub 2009 Dec 3.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109.085407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2836057PMC
February 2010

Mocr: a novel fusion tag for enhancing solubility that is compatible with structural biology applications.

Protein Expr Purif 2009 Jan 12;63(1):40-9. Epub 2008 Sep 12.

High-throughput Protein Lab, Center for Structural Biology, Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue, Ann Arbor, Michigan 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pep.2008.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936452PMC
January 2009