William Bornmann

William Bornmann

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William Bornmann

William Bornmann

Publications by authors named "William Bornmann"

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Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.

Cell Cycle 2014 ;13(16):2587-99

a Department of Experimental Radiation Oncology ; University of Texas MD Anderson Cancer Center ; Houston , TX USA.

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http://dx.doi.org/10.4161/15384101.2015.942210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614451PMC
August 2015

Effect of Iboga alkaloids on µ-opioid receptor-coupled G protein activation.

PLoS One 2013 16;8(10):e77262. Epub 2013 Oct 16.

Department of Psychiatry, New York University School of Medicine, New York, New York, United States of America ; Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0077262PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818563PMC
August 2014

Imatinib analogs as potential agents for PET imaging of Bcr-Abl and c-KIT expression at a kinase level.

Bioorg Med Chem 2014 Jan 6;22(1):623-32. Epub 2013 Nov 6.

Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2013.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124913PMC
January 2014

Curcumin glucuronides: assessing the proliferative activity against human cell lines.

Bioorg Med Chem 2014 Jan 12;22(1):435-9. Epub 2013 Nov 12.

Department of Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2013.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128398PMC
January 2014

Design and Synthesis of an Inositol Phosphate Analog Based on Computational Docking Studies.

Tetrahedron 2014 Jan;70(4):984-990

Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd. Box 603, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.tet.2013.11.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125022PMC
January 2014

Asymmetric Synthesis of the C1-C6 Portion of the Psymberin Using an Evans Chiral Auxiliary.

Tetrahedron Lett 2013 Oct;54(41):5555-5567

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 77030.

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http://dx.doi.org/10.1016/j.tetlet.2013.05.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124943PMC
October 2013

Synthesis of a Macrocycle Based on Linked Amino Acid Mimetics (LAAM).

Tetrahedron Lett 2013 Oct;54(43):5799-5801

Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA 77030.

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http://dx.doi.org/10.1016/j.tetlet.2013.08.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125026PMC
October 2013

Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesion.

J Biol Chem 2013 Jul 23;288(27):19414-28. Epub 2013 May 23.

Department of Molecular Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1074/jbc.M113.479634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707645PMC
July 2013

Binding partners for curcumin in human schwannoma cells: biologic implications.

Bioorg Med Chem 2013 Feb 13;21(4):932-9. Epub 2012 Dec 13.

Department of Investigational Cancer Therapeutics, (Phase I Program), The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1016/j.bmc.2012.12.008DOI Listing
February 2013

A Practical Synthesis and X-ray Crystallographic Analysis of Dithymoquinone, a Photodimer of Thymoquinone.

Lett Org Chem 2012 Dec;9(10):762-766

Department of Pharmacy Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA ; Department of Thoracic Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.2174/157017812803901890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039186PMC
December 2012

Productive replication of Ebola virus is regulated by the c-Abl1 tyrosine kinase.

Sci Transl Med 2012 Feb;4(123):123ra24

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1126/scitranslmed.3003500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794994PMC
February 2012

A novel small molecule deubiquitinase inhibitor blocks Jak2 signaling through Jak2 ubiquitination.

Cell Signal 2011 Dec 9;23(12):2076-85. Epub 2011 Aug 9.

Department of Internal Medicine, Division of Hematology-Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1016/j.cellsig.2011.08.002DOI Listing
December 2011

Tyrphostin-like compounds with ubiquitin modulatory activity as possible therapeutic agents for multiple myeloma.

Bioorg Med Chem 2011 Dec 7;19(23):7194-204. Epub 2011 Oct 7.

Department of Experimental Therapeutics, M D Anderson Cancer Center, Houston, TX 77030, United States.

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http://dx.doi.org/10.1016/j.bmc.2011.09.057DOI Listing
December 2011

Kit inhibitor APcK110 extends survival in an AML xenograft mouse model.

Invest New Drugs 2011 Oct 3;29(5):1094-7. Epub 2010 Jun 3.

Department of Leukemia, Unit 428, MD Anderson Cancer Center, The University of Texas, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10637-010-9459-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251765PMC
October 2011

STAT3 mediates resistance to MEK inhibitor through microRNA miR-17.

Cancer Res 2011 May 28;71(10):3658-68. Epub 2011 Mar 28.

Department of Thoracic and Cardiovascular Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392199PMC
May 2011

Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis.

Blood 2011 Mar 19;117(11):3151-62. Epub 2011 Jan 19.

Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1182/blood-2010-03-276477DOI Listing
March 2011

Variola and monkeypox viruses utilize conserved mechanisms of virion motility and release that depend on abl and SRC family tyrosine kinases.

J Virol 2011 Jan 20;85(1):21-31. Epub 2010 Oct 20.

Microbiology and Molecular Genetics Graduate Program, Emory University School of Medicine, 615 Michael Street, Whitehead Research Building 155, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1128/JVI.01814-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014172PMC
January 2011

Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy.

Clin Cancer Res 2011 Jan 11;17(2):275-85. Epub 2011 Jan 11.

Department of Pharmacology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806682PMC
January 2011

Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis.

Cancer Res 2010 Nov 2;70(22):9265-76. Epub 2010 Nov 2.

Division of Hematology-Oncology, Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1530DOI Listing
November 2010

Degrasyn potentiates the antitumor effects of bortezomib in mantle cell lymphoma cells in vitro and in vivo: therapeutic implications.

Mol Cancer Ther 2010 Jul 6;9(7):2026-36. Epub 2010 Jul 6.

Department of Hematopathology, Unit 54, The University of Texas of M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-0238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483974PMC
July 2010

Suberoylanilide hydroxamic acid blocks self-renewal and homotypic aggregation of inflammatory breast cancer spheroids.

Cancer 2010 Jun;116(11 Suppl):2760-7

The Morgan Welch Inflammatory Breast Cancer Research Program, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1002/cncr.25176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548985PMC
June 2010

Abl family tyrosine kinases regulate sialylated ganglioside receptors for polyomavirus.

J Virol 2010 May 24;84(9):4243-51. Epub 2010 Feb 24.

Department of Pathology and Laboratory Medicine, Emory University, Whitehead Research Bldg. 144, 615 Michael St., Atlanta, GA 30322, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.00129-10
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http://dx.doi.org/10.1128/JVI.00129-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863717PMC
May 2010

Beta-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy.

Cancer Res 2010 May 11;70(10):3896-904. Epub 2010 May 11.

Departments of Pharmacology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, Texas 75390-8807, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873165PMC
May 2010

Multiple phosphatidylinositol 3-kinases regulate vaccinia virus morphogenesis.

PLoS One 2010 May 28;5(5):e10884. Epub 2010 May 28.

Microbiology and Molecular Genetics Graduate Program, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010884PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878334PMC
May 2010

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction.

J Clin Invest 2010 Jan 21;120(1):142-56. Epub 2009 Dec 21.

Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1172/JCI38942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799198PMC
January 2010

Demonstration of microtubule-like structures formed with (-)-rhazinilam from purified tubulin outside of cells and a simple tubulin-based assay for evaluation of analog activity.

Arch Biochem Biophys 2009 Jul 2;487(2):98-104. Epub 2009 Jun 2.

Toxicology and Pharmacology Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000398610900172
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http://dx.doi.org/10.1016/j.abb.2009.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726660PMC
July 2009

Combining PCI-24781, a novel histone deacetylase inhibitor, with chemotherapy for the treatment of soft tissue sarcoma.

Clin Cancer Res 2009 May 5;15(10):3472-83. Epub 2009 May 5.

Department of Cancer Biology, Sarcoma Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2714DOI Listing
May 2009

Molecular-genetic PET imaging using an HSV1-tk mutant reporter gene with enhanced specificity to acycloguanosine nucleoside analogs.

J Nucl Med 2009 Mar 17;50(3):409-16. Epub 2009 Feb 17.

Experimental Diagnostic Imaging, University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.2967/jnumed.108.058735DOI Listing
March 2009

Intratumoral delivery of beta-lapachone via polymer implants for prostate cancer therapy.

Clin Cancer Res 2009 Jan;15(1):131-9

Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-1691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845536PMC
January 2009

Monitoring histone deacetylase inhibition in vivo: noninvasive magnetic resonance spectroscopy method.

Mol Imaging 2008 Mar-Apr;7(2):92-100

Experimental Diagnostic Imaging, Imaging Physics, and Experimental Therapeutics, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

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November 2008

Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin.

Mol Carcinog 2008 Oct;47(10):739-43

Department of Molecular and Cellular Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/mc.20423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596649PMC
October 2008

Role of c-Abl kinase in DNA mismatch repair-dependent G2 cell cycle checkpoint arrest responses.

J Biol Chem 2008 Aug 14;283(31):21382-93. Epub 2008 May 14.

Laboratory of Molecular Stress Responses, Program in Cell Stress and Cancer Nanomedicine, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1074/jbc.M709953200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490779PMC
August 2008

Activity of lapatinib is independent of EGFR expression level in HER2-overexpressing breast cancer cells.

Mol Cancer Ther 2008 Jul;7(7):1846-50

Department of Breast Medical Oncology, Unit 1354, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-08-0168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525738PMC
July 2008

Evaluation of 2'-deoxy-2'-[18F]fluoro-5-methyl-1-beta-L: -arabinofuranosyluracil ([18F]-L: -FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-D: -FMAU and [18F]FLT.

Eur J Nucl Med Mol Imaging 2008 May 4;35(5):990-8. Epub 2007 Dec 4.

Department of Experimental Diagnostic Imaging, M. D. Anderson Cancer Center, The University of Texas, Box 059, T8.3895, 1515 Holcombe Blvd, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s00259-007-0649-1DOI Listing
May 2008

Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).

Cancer Res 2008 May;68(9):3413-20

Section of Molecular Hematology and Therapy, Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-07-1919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096127PMC
May 2008

Mechanism of activation and inhibition of the HER4/ErbB4 kinase.

Structure 2008 Mar;16(3):460-7

Department of Biophysics & Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.str.2007.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858219PMC
March 2008

Radiosynthesis of 2'-deoxy-2'-[18F]-fluoro-5-methyl-1-beta-L-arabinofuranosyluracil ([18F]-L-FMAU) for PET.

Appl Radiat Isot 2007 Aug 14;65(8):941-6. Epub 2007 Apr 14.

Department of Experimental Diagnostic Imaging, University of Texas M D Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1016/j.apradiso.2007.04.003DOI Listing
August 2007

An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone.

Proc Natl Acad Sci U S A 2007 Jul 3;104(28):11832-7. Epub 2007 Jul 3.

Department of Pharmacology, Laboratory of Molecular Stress Responses, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.0702176104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913860PMC
July 2007

Degrasyn activates proteasomal-dependent degradation of c-Myc.

Cancer Res 2007 Apr;67(8):3912-8

Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4464DOI Listing
April 2007

Enteropathogenic Escherichia coli Tir is an SH2/3 ligand that recruits and activates tyrosine kinases required for pedestal formation.

Mol Microbiol 2007 Mar;63(6):1748-68

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2007.05626.xDOI Listing
March 2007

Concomitant inhibition of MDM2 and Bcl-2 protein function synergistically induce mitochondrial apoptosis in AML.

Cell Cycle 2006 Dec 1;5(23):2778-86. Epub 2006 Dec 1.

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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https://www.tandfonline.com/doi/full/10.4161/cc.5.23.3520
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http://dx.doi.org/10.4161/cc.5.23.3520DOI Listing
December 2006

Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.

Cancer Res 2006 Oct;66(19):9714-21

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-4280DOI Listing
October 2006

Detection of histone deacetylase inhibition by noninvasive magnetic resonance spectroscopy.

Mol Cancer Ther 2006 May;5(5):1325-34

Experimental Diagnostic Imaging, The University of Texas M.D. Anderson Cancer Center, 57-3D, 1515 Holcombe Blvd., Houston, TX 77030-4009, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0494DOI Listing
May 2006

A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis.

Mol Pharmacol 2006 Apr 12;69(4):1182-93. Epub 2006 Jan 12.

Section of Molecular Hematology and Therapy, Department of Blood and Marrow Transplantation, Unit 448, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://molpharm.aspetjournals.org/content/69/4/1182.full.pdf
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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.105.01
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http://dx.doi.org/10.1124/mol.105.018051DOI Listing
April 2006

Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells.

Cancer Res 2006 Apr;66(7):3773-81

Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2961DOI Listing
April 2006

Protein kinase Calpha and epsilon small-molecule targeted therapeutics: a new roadmap to two Holy Grails in drug discovery?

Expert Rev Anticancer Ther 2006 Feb;6(2):175-86

U.T. MD Anderson Cancer Center, Box 173, Houston, TX 77030, USA.

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http://dx.doi.org/10.1586/14737140.6.2.175DOI Listing
February 2006

Disabling poxvirus pathogenesis by inhibition of Abl-family tyrosine kinases.

Nat Med 2005 Jul 26;11(7):731-9. Epub 2005 Jun 26.

Microbiology and Molecular Genetics Graduate Program, Emory University School of Medicine, 615 Michael Street, Whitehead Research Building #144, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1038/nm1265DOI Listing
July 2005

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia.

Blood 2005 May 18;105(10):3995-4003. Epub 2005 Jan 18.

Division of Hematology/Oncology, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8593, USA.

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http://dx.doi.org/10.1182/blood-2004-09-3534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895078PMC
May 2005

Synthesis of selected LeY and KH-1 analogues: a medicinal chemistry approach to vaccine optimization.

J Org Chem 2005 Apr;70(9):3383-95

Organic Synthesis Core Facility, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1021/jo048016lDOI Listing
April 2005

An 19F magnetic resonance-based in vivo assay of solid tumor methotrexate resistance: proof of principle.

Clin Cancer Res 2005 Feb;11(4):1454-61

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-1439DOI Listing
February 2005

Susceptibility of cancer cells to beta-lapachone is enhanced by ionizing radiation.

Int J Radiat Oncol Biol Phys 2005 Jan;61(1):212-9

Radiobiology Laboratory, Department of Therapeutic Radiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2004.09.018DOI Listing
January 2005

Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1.

Cancer Biol Ther 2005 Jan 15;4(1):95-102. Epub 2005 Jan 15.

Department of Surgery, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.4161/cbt.4.1.1382DOI Listing
January 2005

Enteropathogenic Escherichia coli use redundant tyrosine kinases to form actin pedestals.

Mol Biol Cell 2004 Aug 21;15(8):3520-9. Epub 2004 May 21.

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1091/mbc.e04-02-0093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC491815PMC
August 2004

B cell signaling is regulated by induced palmitoylation of CD81.

J Biol Chem 2004 Jul 25;279(30):31973-82. Epub 2004 May 25.

Laboratory of Immunogenetics, NIAID, National Institutes of Health, Rockville, Maryland 20852, USA.

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http://dx.doi.org/10.1074/jbc.M404410200DOI Listing
July 2004

A novel triple-modality reporter gene for whole-body fluorescent, bioluminescent, and nuclear noninvasive imaging.

Eur J Nucl Med Mol Imaging 2004 May 11;31(5):740-51. Epub 2004 Mar 11.

Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1007/s00259-003-1441-5DOI Listing
May 2004

Specific tumour localisation of a huA33 antibody--carboxypeptidase A conjugate and activation of methotrexate-phenylalanine.

Int J Oncol 2004 May;24(5):1289-95

Medizinische Klinik III - Haematology, Oncology and Transfusion Medicine, Charité - Campus Benjamin Franklin, D-12200 Berlin, Germany.

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May 2004

A new human peptide deformylase inhibitable by actinonin.

Biochem Biophys Res Commun 2003 Dec;312(2):309-15

Department of Pharmacology, Weill Graduate School of Medical Sciences of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.bbrc.2003.10.123DOI Listing
December 2003

Activation of a camptothecin prodrug by specific carboxylesterases as predicted by quantitative structure-activity relationship and molecular docking studies.

Mol Cancer Ther 2003 Nov;2(11):1171-81

Department of Molecular Pharmacology, St. Jude Children's Research Hospital, Memphis, TN 38015, USA.

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November 2003

Gleevec inhibits beta-amyloid production but not Notch cleavage.

Proc Natl Acad Sci U S A 2003 Oct 1;100(21):12444-9. Epub 2003 Oct 1.

Fisher Center for Research on Alzheimer's Disease, Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, NY 10021, USA..

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http://dx.doi.org/10.1073/pnas.1534745100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC218777PMC
October 2003

Inhibition of wild-type and mutant Bcr-Abl by pyrido-pyrimidine-type small molecule kinase inhibitors.

Cancer Res 2003 Oct;63(19):6395-404

Department of Internal Medicine III, Technical University of Munich, Trogerstrasse 32, D-81675 Munich, Germany.

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October 2003

A fluorine-labeled methotrexate as a probe for monitoring tumor antifolate pharmacokinetics: synthesis, in vitro cytotoxicity, and pilot in vivo 19F magnetic resonance spectra.

Mol Cancer Ther 2003 Oct;2(10):933-9

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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October 2003

Enhancement of solubility and bioavailability of beta-lapachone using cyclodextrin inclusion complexes.

Pharm Res 2003 Oct;20(10):1626-33

Department of Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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October 2003