Wilhelm J Schwaeble

Wilhelm J Schwaeble

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Wilhelm J Schwaeble

Wilhelm J Schwaeble

Publications by authors named "Wilhelm J Schwaeble"

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Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury.

Front Immunol 2019 23;10:2238. Epub 2019 Sep 23.

Department of Infection, Immunity and Inflammation, College of Life Sciences, University of Leicester, Leicester, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2019.02238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6768126PMC
September 2019

Properdin binds independent of complement activation in an in vivo model of anti-glomerular basement membrane disease.

Kidney Int 2018 12 12;94(6):1141-1150. Epub 2018 Oct 12.

Leiden University Medical Center, Department of Nephrology, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.06.030DOI Listing
December 2018

Reply to Mortensen et al.: The zymogen form of complement component C1.

Proc Natl Acad Sci U S A 2018 04 13;115(17):E3867-E3868. Epub 2018 Apr 13.

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1804497115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924941PMC
April 2018

Structure of the C1r-C1s interaction of the C1 complex of complement activation.

Proc Natl Acad Sci U S A 2018 01 8;115(4):768-773. Epub 2018 Jan 8.

Department of Infection, Immunity, and Inflammation, University of Leicester, Leicester LE1 9HN, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1718709115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789954PMC
January 2018

A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway.

Mol Immunol 2016 05 6;73:76-87. Epub 2016 Apr 6.

Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge UB8 3PH, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01615890163003
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http://dx.doi.org/10.1016/j.molimm.2016.03.005DOI Listing
May 2016

Properdin Regulation of Complement Activation Affects Colitis in Interleukin 10 Gene-Deficient Mice.

Inflamm Bowel Dis 2015 Jul;21(7):1519-28

Departments of *Microbiology and Immunology, and †Pathology, Dalhousie University, Halifax, NS, Canada; ‡Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom; and §Department of Pediatrics, Dalhousie University, Halifax, NS, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000398DOI Listing
July 2015

Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6-dependent manner.

J Immunol 2015 Apr 27;194(7):3414-21. Epub 2015 Feb 27.

Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada; Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia B3H 4H7, Canada

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1401814
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http://dx.doi.org/10.4049/jimmunol.1401814DOI Listing
April 2015

Deficiency in mannose-binding lectin-associated serine protease-2 does not increase susceptibility to Trypanosoma cruzi infection.

Am J Trop Med Hyg 2015 Feb 29;92(2):320-4. Epub 2014 Dec 29.

Programa Disciplinario de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago, Chile; Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom; Department of Microbiology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

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http://dx.doi.org/10.4269/ajtmh.14-0236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347335PMC
February 2015

Role of ficolin-A and lectin complement pathway in the innate defense against pathogenic Aspergillus species.

Infect Immun 2013 May 11;81(5):1730-40. Epub 2013 Mar 11.

Norwich Medical School, University of East Anglia, Norwich, United Kingdom.

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http://dx.doi.org/10.1128/IAI.00032-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647983PMC
May 2013

The complement system in ischemia-reperfusion injuries.

Immunobiology 2012 Nov 7;217(11):1026-33. Epub 2012 Aug 7.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.imbio.2012.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439809PMC
November 2012

Which pathways trigger the role of complement in ischaemia/reperfusion injury?

Front Immunol 2012 19;3:341. Epub 2012 Nov 19.

MRC Centre for Transplantation, Division of Transplantation Immunology and Mucosal Biology, King's College London School of Medicine at Guy's, King's College and St Thomas' Hospitals London, UK.

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http://dx.doi.org/10.3389/fimmu.2012.00341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500775PMC
November 2012

Absence of the lectin activation pathway of complement does not increase susceptibility to Pseudomonas aeruginosa infections.

Immunobiology 2012 Feb 13;217(2):272-80. Epub 2011 Oct 13.

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1016/j.imbio.2011.10.001DOI Listing
February 2012

Use of recombinant calreticulin and cercarial transformation fluid (CTF) in the serodiagnosis of Schistosoma mansoni.

Immunobiology 2011 Mar 15;216(3):379-85. Epub 2010 Jul 15.

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.1016/j.imbio.2010.06.014DOI Listing
March 2011

The lectin pathway of complement activation contributes to protection from West Nile virus infection.

Virology 2011 Mar 26;412(1):101-9. Epub 2011 Jan 26.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave., St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.virol.2011.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057364PMC
March 2011

Paths reunited: Initiation of the classical and lectin pathways of complement activation.

Immunobiology 2010 27;215(1):1-11. Epub 2009 Sep 27.

Department of Infection, Immunity and Inflammation, University of Leicester, UK.

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http://dx.doi.org/10.1016/j.imbio.2009.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824237PMC
May 2010

Engineering novel complement activity into a pulmonary surfactant protein.

J Biol Chem 2010 Apr 29;285(14):10546-52. Epub 2010 Jan 29.

Department of Infection, Immunity, and Inflammation, University of Leicester, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.1074/jbc.M109.097493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856262PMC
April 2010

Properdin deficiency in murine models of nonseptic shock.

J Immunol 2008 May;180(10):6962-9

Department of Immunology, Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.

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http://dx.doi.org/10.4049/jimmunol.180.10.6962DOI Listing
May 2008

Properdin plays a protective role in polymicrobial septic peritonitis.

J Immunol 2008 Mar;180(5):3313-8

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.4049/jimmunol.180.5.3313DOI Listing
March 2008

Molecular interactions between MASP-2, C4, and C2 and their activation fragments leading to complement activation via the lectin pathway.

J Biol Chem 2007 Mar 3;282(11):7844-51. Epub 2007 Jan 3.

Department of Infection, Immunity, and Inflammation, University of Leicester, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M606326200DOI Listing
March 2007

Small mannose-binding lectin-associated protein plays a regulatory role in the lectin complement pathway.

J Immunol 2006 Dec;177(12):8626-32

Department of Immunology, Fukushima Medical University, 1-Hikariga-oka, Fukushima City 960-1295, Japan.

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http://dx.doi.org/10.4049/jimmunol.177.12.8626DOI Listing
December 2006

Investigations on the involvement of the lectin pathway of complement activation in anaphylaxis.

Int Arch Allergy Immunol 2006 23;141(1):11-23. Epub 2006 Jun 23.

Institute of Immunology, University of Regensburg, Regensburg, Germany, and Department of Pediatrics, Laboratory of Developmental Immunology, Massachusetts General Hospital, Boston, USA.

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http://dx.doi.org/10.1159/000094177DOI Listing
September 2006

Localization of the mouse defense lectin ficolin B in lysosomes of activated macrophages.

J Endotoxin Res 2006 ;12(2):120-6

Institute of Immunology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1179/096805106X102147DOI Listing
May 2006

Decoupling of carbohydrate binding and MASP-2 autoactivation in variant mannose-binding lectins associated with immunodeficiency.

J Immunol 2005 Nov;175(10):6846-51

Department of Infection, Immunity, and Inflammation, University of Leicester, Leicester, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.175.10.6846DOI Listing
November 2005

Composition of the lectin pathway of complement in Gallus gallus: absence of mannan-binding lectin-associated serine protease-1 in birds.

J Immunol 2005 Apr;174(8):4998-5006

Department of Infection, Immunity, and Inflammation, University of Leicester, Leicester, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.174.8.4998DOI Listing
April 2005

Organization of the MASP2 locus and its expression profile in mouse and rat.

Mamm Genome 2004 Nov;15(11):887-900

Department of Infection, Immunity and Inflammation, University of Leicester, Leicester LE1 9HN, United Kingdom.

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http://dx.doi.org/10.1007/s00335-004-3006-8DOI Listing
November 2004

Microglial activation and increased synthesis of complement component C1q precedes blood-brain barrier dysfunction in rats.

Mol Immunol 2004 Jan;40(10):709-16

Department of Infection, Immunity and Inflammation, University of Leicester, University Road, Leicester LE1 9HN, UK.

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http://dx.doi.org/10.1016/j.molimm.2003.08.009DOI Listing
January 2004

Differential expression of the murine mannose-binding lectins A and C in lymphoid and nonlymphoid organs and tissues.

J Immunol 2003 Feb;170(3):1462-5

Institute of Medical Microbiology and Hygiene, Johannes Gutenberg University, Mainz, Germany.

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http://dx.doi.org/10.4049/jimmunol.170.3.1462DOI Listing
February 2003

Functional characterization of human mannose-binding lectin-associated serine protease (MASP)-1/3 and MASP-2 promoters, and comparison with the C1s promoter.

Int Immunol 2002 Oct;14(10):1193-201

Department of Biochemistry, Fukushima Medical University School of Medicine, 1-Hikarigaoka, Fukushima 960-1295, Japan.

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http://dx.doi.org/10.1093/intimm/dxf085DOI Listing
October 2002

In vivo pharmacokinetics of calreticulin S-domain, an inhibitor of the classical complement pathway.

Int Immunopharmacol 2002 Mar;2(4):415-22

Department of Microbiology and Immunology, University of Leicester, UK.

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http://dx.doi.org/10.1016/s1567-5769(01)00165-5DOI Listing
March 2002