Publications by authors named "Wilfried Rossoll"

35Publications

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36.

Neuron 2020 07 5;107(2):292-305.e6. Epub 2020 May 5.

Department of Cell Biology, Emory University, Atlanta, GA 30322, USA; Laboratory for Translational Cell Biology, Emory University, Atlanta, GA 30322, USA; Wallace H. Coulter Graduate Program in Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, GA 30332, USA; Department of Neurology, Emory University, Atlanta, GA 30322, USA. Electronic address:

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July 2020

Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS/FTD.

Neurobiol Dis 2020 07 14;140:104835. Epub 2020 Mar 14.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA. Electronic address:

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July 2020

Crosstalk of Local Translation and Mitochondria: Powering Plasticity in Axons and Dendrites.

Neuron 2019 01;101(2):204-206

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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January 2019

RNP Assembly Defects in Spinal Muscular Atrophy.

Adv Neurobiol 2018 ;20:143-171

Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.

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October 2018

mRNP assembly, axonal transport, and local translation in neurodegenerative diseases.

Brain Res 2018 08 17;1693(Pt A):75-91. Epub 2018 Feb 17.

Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224 USA. Electronic address:

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August 2018

Post-transcriptional Inhibition of Hsc70-4/HSPA8 Expression Leads to Synaptic Vesicle Cycling Defects in Multiple Models of ALS.

Cell Rep 2017 Oct;21(1):110-125

Department of Molecular and Cellular Biology, University of Arizona, Tucson, AZ 85721, USA; Department of Neuroscience, University of Arizona, Tucson, AZ 85721, USA; Department of Neurology, University of Arizona, Tucson, AZ 85721, USA. Electronic address:

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October 2017

Spatially and temporally regulating translation via mRNA-binding proteins in cellular and neuronal function.

FEBS Lett 2017 06 3;591(11):1508-1525. Epub 2017 Apr 3.

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA.

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June 2017

The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly.

Cell Rep 2017 02;18(7):1660-1673

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA; Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, USA; Laboratory of Translational Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address:

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February 2017

Dysregulation of mRNA Localization and Translation in Genetic Disease.

J Neurosci 2016 11;36(45):11418-11426

Department of Cell Biology and Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, Georgia 30322, and

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November 2016

A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses.

Dis Model Mech 2016 09 4;9(9):927-39. Epub 2016 Aug 4.

Division of Pediatric Cardiology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, GA 30322, USA Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30322, USA

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September 2016

A role for the survival of motor neuron protein in mRNP assembly and transport.

Curr Opin Neurobiol 2016 08 29;39:53-61. Epub 2016 Apr 29.

Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

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August 2016

PABPN1 suppresses TDP-43 toxicity in ALS disease models.

Hum Mol Genet 2015 Sep 30;24(18):5154-73. Epub 2015 Jun 30.

Department of Cell Biology, Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, USA,

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September 2015

The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.

Hum Mol Genet 2012 Aug 28;21(16):3703-18. Epub 2012 May 28.

Department of Cell Biology and Center for Neurodegenerative Diseases, Emory University School of Medicine, Atlanta, GA 30322, USA.

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August 2012

Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.

Brain Res 2012 Jun 28;1462:81-92. Epub 2012 Jan 28.

Department of Cell Biology, School of Medicine, Emory University School of Medicine, Atlanta 30322, USA.

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June 2012

High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function.

Mol Neurodegener 2010 Apr 21;5:17. Epub 2010 Apr 21.

Department of Cell Biology, Emory University School of Medicine, Atlanta 30322, USA.

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April 2010

Spinal muscular atrophy and a model for survival of motor neuron protein function in axonal ribonucleoprotein complexes.

Results Probl Cell Differ 2009 ;48:289-326

Departments of Cell Biology and Neurology, Center for Neurodegenerative Disease, Emory University School of Medicine, Atlanta, GA 30322, USA.

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April 2010

Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons.

J Neurosci 2006 Aug;26(33):8622-32

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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August 2006

Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells.

Proc Natl Acad Sci U S A 2006 May 9;103(20):7871-6. Epub 2006 May 9.

Institute for Clinical Neurobiology, University of Wuerzburg, D-97080 Wuerzburg, Germany.

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May 2006

Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.

Nat Neurosci 2005 Sep 21;8(9):1169-78. Epub 2005 Aug 21.

Institut für Klinische Neurobiologie, University of Würzburg, Josef Schneider Str. 11, D-97080 Würzburg, Germany.

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September 2005

Gene targeting of Gemin2 in mice reveals a correlation between defects in the biogenesis of U snRNPs and motoneuron cell death.

Proc Natl Acad Sci U S A 2002 Jul 28;99(15):10126-31. Epub 2002 Jun 28.

Institute of Clinical Neurobiology, Josef-Schneider Strasse 11, D-97080 Würzburg, Germany.

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July 2002

Specific interaction of Smn, the spinal muscular atrophy determining gene product, with hnRNP-R and gry-rbp/hnRNP-Q: a role for Smn in RNA processing in motor axons?

Hum Mol Genet 2002 Jan;11(1):93-105

Institut für Klinische Neurobiologie, Department of Neurology, University of Würzburg, Josef-Schneider Strasse 11, D-97080 Würzburg, Germany.

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January 2002