Publications by authors named "Wilfried Le Goff"

73Publications

Interleukin-1β and Risk of Premature Death in Patients With Myocardial Infarction.

J Am Coll Cardiol 2020 Oct 27;76(15):1763-1773. Epub 2020 Aug 27.

INSERM UMRS1166 Hôpital de la Pitié, Paris, France, Sorbonne Université, Paris, France, ICAN - Institute of CardioMetabolism and Nutrition, Hôpital de la Pitié, Paris, France.

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http://dx.doi.org/10.1016/j.jacc.2020.08.026DOI Listing
October 2020

Rewiring of Lipid Metabolism in Adipose Tissue Macrophages in Obesity: Impact on Insulin Resistance and Type 2 Diabetes.

Int J Mol Sci 2020 Jul 31;21(15). Epub 2020 Jul 31.

Institute of Cardiometabolism and Nutrition (ICAN), Hôpital de la Pitié, Sorbonne Université, Inserm, UMR_S1166, 75013 Paris, France.

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http://dx.doi.org/10.3390/ijms21155505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432680PMC
July 2020

Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis.

Immunity 2020 Sep 19;53(3):627-640.e5. Epub 2020 Jun 19.

Institut National de la Santé et de la Recherche Médicale (Inserm, UMR_S 1166), Sorbonne Université, Hôpital de la Pitié-Salpêtrière, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.003DOI Listing
September 2020

Reduced Reverse Cholesterol Transport Efficacy in Healthy Men with Undesirable Postprandial Triglyceride Response.

Biomolecules 2020 05 25;10(5). Epub 2020 May 25.

Research Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.

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http://dx.doi.org/10.3390/biom10050810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277968PMC
May 2020

Interplay between Liver X Receptor and Hypoxia Inducible Factor 1α Potentiates Interleukin-1β Production in Human Macrophages.

Cell Rep 2020 05;31(7):107665

Université Bourgogne Franche-Comté, LNC UMR1231, 21000 Dijon, France; INSERM, LNC UMR1231, 21000 Dijon, France; FCS Bourgogne-Franche Comté, LipSTIC LabEx, 21000 Dijon, France; CHRU Dijon Bourgogne, Laboratory of Clinical Chemistry, 21000 Dijon, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107665DOI Listing
May 2020

Identification of the first Tangier disease patient in Lebanon carrying a new pathogenic variant in ABCA1.

J Clin Lipidol 2018 Nov - Dec;12(6):1374-1382. Epub 2018 Sep 1.

Laboratory of Biochemistry and Molecular Therapeutics, Faculty of Pharmacy, Pôle Technologie- Santé, Saint Joseph University, Beirut, Lebanon; INSERM LVTS U1148, Hôpital Bichat-Claude Bernard, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2018.08.013DOI Listing
October 2019

Impairment of chondrogenesis and microfibrillar network in Adamtsl2 deficiency.

FASEB J 2019 02 10;33(2):2707-2718. Epub 2018 Oct 10.

INSERM Unité Mixte de Recherche (UMR) 1163, Laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia, Imagine Institute, Paris Descartes University-Sorbonne Paris Cité, Paris, France.

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https://www.fasebj.org/doi/10.1096/fj.201800753RR
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http://dx.doi.org/10.1096/fj.201800753RRDOI Listing
February 2019

Hypoalphalipoproteinemia and BRAF Mutation Are Major Predictors of Aortic Infiltration in the Erdheim-Chester Disease.

Arterioscler Thromb Vasc Biol 2018 08;38(8):1913-1925

Inserm, Institute of Cardiometabolism and Nutrition (ICAN), UMR_S1166, Hôpital de la Pitié, Sorbonne Université, Paris, France (M.G., F.S.-C., Y.A., E.F., P.L., W.L.G.).

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http://dx.doi.org/10.1161/ATVBAHA.118.310803DOI Listing
August 2018

Critical Role of the Human ATP-Binding Cassette G1 Transporter in Cardiometabolic Diseases.

Int J Mol Sci 2017 Sep 2;18(9). Epub 2017 Sep 2.

Sorbonne Universités, UPMC Univ Paris 06, Inserm, Institute of Cardiometabolism and Nutrition (ICAN), UMR_S1166, Hôpital de la Pitié, F-75013 Paris, France.

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http://dx.doi.org/10.3390/ijms18091892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618541PMC
September 2017

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans.

G3 (Bethesda) 2016 10 13;6(10):3361-3371. Epub 2016 Oct 13.

Sorbonne Universités, Université Pierre et Marie Curie, Paris 06, Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche en Santé 1166, F-75013 Paris, France Institute for Cardiometabolism and Nutrition, F-75013 Paris, France

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http://dx.doi.org/10.1534/g3.116.033894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068955PMC
October 2016

Heterozygous Mutations in MAP3K7, Encoding TGF-β-Activated Kinase 1, Cause Cardiospondylocarpofacial Syndrome.

Am J Hum Genet 2016 08 14;99(2):407-13. Epub 2016 Jul 14.

Department of Medical Genetics, Reference Center for Skeletal Dysplasia, INSERM UMR 1163, Laboratory of Molecular and Physiopathological Bases of Osteochondrodysplasia, Paris Descartes-Sorbonne Paris Cité University, AP-HP, Institut Imagine, and Hôpital Universitaire Necker-Enfants Malades, 75015 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974068PMC
August 2016

Lipidomic approach provides new clues toward solving the mystery of accelerated atherosclerosis in diabetes.

Atherosclerosis 2016 08 11;251:507-509. Epub 2016 Jun 11.

Sorbonne Universités, UPMC Univ Paris 06, INSERM, ICAN, Institute of Cardiometabolism and Nutrition (UMR_S1166), Integrative Biology of Atherosclerosis Team, 91 boulevard de l'hôpital, F-75013, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.06.007DOI Listing
August 2016

Extended-Release Niacin/Laropiprant Improves Overall Efficacy of Postprandial Reverse Cholesterol Transport.

Arterioscler Thromb Vasc Biol 2016 Feb 17;36(2):285-94. Epub 2015 Dec 17.

From the INSERM, Sorbonne Universités, UPMC Univ Paris 06, UMRS-1166 Hôpital de la Pitié, Paris, France (P.E.K., T.H., J.G., P.C., J.-M.L., E.F., P.L., W.L.G., M.G.); University Saint-Joseph, Beyrouth, Lebanon (P.E.K.); ICAN-Institute of CardioMetabolism and Nutrition, Hôpital de la Pitié, Paris, France (T.H., P.C., J.-M.L., E.F., P.L., W.L.G., M.G.); University of Munich, Munich, Germany (E.W., K.G.P.); and INSERM, Emeritus Research Director (J.C.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306834DOI Listing
February 2016

Therapeutic applications of reconstituted HDL: When structure meets function.

Pharmacol Ther 2016 Jan 10;157:28-42. Epub 2015 Nov 10.

UMR INSERM-UPMC 1166 ICAN, Pavillon Benjamin Delessert, Hôpital de la Pitié, 83 boulevard de l'Hôpital, 75651 Paris Cedex 13, France. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2015.10.010DOI Listing
January 2016

Adipose ABCG1: A potential therapeutic target in obesity?

Adipocyte 2015 Oct-Dec;4(4):315-8. Epub 2015 Mar 9.

INSERM; UMR_S1166; Team 4 ; Paris, France ; Université Pierre et Marie Curie-Paris6 ; Paris, France ; Institute of Cardiometabolism and Nutrition (ICAN); Pitié-Salpêtrière Hospital ; Paris, France.

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http://dx.doi.org/10.1080/21623945.2015.1023491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573181PMC
October 2015

The spectrum of neutrophilic dermatoses associated with monoclonal gammopathy: Association with IgA isotype and inflammatory profile.

J Am Acad Dermatol 2015 Nov 11;73(5):809-20. Epub 2015 Sep 11.

Department of Clinical Immunology, Saint-Louis Hospital, Assistance Publique des Hopitaux de Paris, Paris, France; Institut National de la Sante et de la Recherche Medicale (INSERM) Unite Mixte de Recherche (UMR)_1126, Institut Universitaire d'Hematologie, Universite Paris 7 Denis Diderot, Paris, France; Groupe d'Etude des Dermatoses associées à une Immunoglobuline Monoclonale, Paris, France.

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http://dx.doi.org/10.1016/j.jaad.2015.07.031DOI Listing
November 2015

Promoting macrophage survival delays progression of pre-existing atherosclerotic lesions through macrophage-derived apoE.

Cardiovasc Res 2015 Oct 19;108(1):111-23. Epub 2015 Jun 19.

INSERM, UMR_S U1166, Integrative Biology of Atherosclerosis Team, Hôpital de la Pitié, Pavillon Benjamin Delessert, 83 Boulevard de L'hôpital, Paris F-75013, France Sorbonne Universités, UPMC Université Paris 06, UMR_S 1166, ICAN, Integrative Biology of Atherosclerosis Team, Paris F-75005, France Institute of Cardiometabolism and Nutrition, ICAN, AP-HP, Pitié-Salpêtrière Hospital, Paris F-75013, France

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http://dx.doi.org/10.1093/cvr/cvv177DOI Listing
October 2015

HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export.

Circ Res 2015 Mar 14;116(7):1133-42. Epub 2015 Jan 14.

From the Centre for Vascular Research, University of New South Wales, Sydney, New South Wales, Australia (X.-M.D., M.-J.K., L.H., S.P.C., C.M.Q., K.-A.R); INSERM, UMR_1166, Research Institute of Cardiovascular Disease, Metabolism and Nutrition, Pitié-Salpétrière University Hospital, Paris, France (W.L.G., M.J.C., A.K.); Université Pierre et Marie Curie-Paris 6, Paris, France (W.L.G., M.J.C., A.K.); Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands (M.V.E.); Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA (L.K.C.); Department of Clinical Biochemistry, Royal Perth Hospital, Perth, Western Australia, Australia (J.R.B.); School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia (J.R.B.); Atherosclerosis Laboratory, ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia (M.K., L.K., W.J.); and Department of Cardiology, Concord Hospital, Sydney, New South Wales, Australia (L.K.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.305485DOI Listing
March 2015

Plasma cholesterol efflux capacity from human THP-1 macrophages is reduced in HIV-infected patients: impact of HAART.

J Lipid Res 2015 Mar 8;56(3):692-702. Epub 2015 Jan 8.

Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS1166, Hôpital de la Pitié, Paris, France Sorbonne Universités, UMPC Univ Paris 6, Paris, France ICAN Institute of Cardiometabolism and Nutrition, Hôpital de la Pitié, Paris, France.

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http://www.jlr.org/content/early/2015/01/08/jlr.M054510.full
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http://www.jlr.org/lookup/doi/10.1194/jlr.M054510
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http://dx.doi.org/10.1194/jlr.M054510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340316PMC
March 2015

A new piece in the puzzling effect of n-3 fatty acids on atherosclerosis?

Authors:
Wilfried Le Goff

Atherosclerosis 2014 Aug 22;235(2):358-62. Epub 2014 May 22.

INSERM UMR_S1166, Team 4: Integrative Biology of Atherosclerosis, F-75013 Paris, France; Université Pierre et Marie Curie-Paris6, F-75005 Paris, France; Institute of Cardiometabolism and Nutrition (ICAN), Pitié-Salpêtrière Hospital, F-75013 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.03.038DOI Listing
August 2014

Improved plasma cholesterol efflux capacity from human macrophages in patients with hyperalphalipoproteinemia.

Atherosclerosis 2014 May 12;234(1):193-9. Epub 2014 Mar 12.

INSERM-UPMC UMR1166, Hôpital de la Pitié, Paris, France; ICAN-Institute of CardioMetabolism and Nutrition, Hôpital de la Pitié, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.02.032DOI Listing
May 2014

Small, dense high-density lipoprotein-3 particles are enriched in negatively charged phospholipids: relevance to cellular cholesterol efflux, antioxidative, antithrombotic, anti-inflammatory, and antiapoptotic functionalities.

Arterioscler Thromb Vasc Biol 2013 Dec 3;33(12):2715-23. Epub 2013 Oct 3.

From the National Institute for Health and Medical Research (INSERM), Dyslipidemia, Inflammation and Atherosclerosis Research Unit (UMR 939), Paris, France (L.C., M.L., F.R., W.L.G., M.J.C., A.K.); Université Pierre et Marie Curie - Paris 6, Paris, France (L.C., M.L., F.R., W.L.G., M.J.C., A.K.); AP-HP, Groupe Hospitalier Pitié Salpétrière, Paris, France (L.C., M.L., F.R., W.L.G., M.J.C., A.K.); ICAN, Paris, France (L.C., M.L., F.R., W.L.G., M.J.C., A.K.); Heart Institute-InCor, University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil (F.R.); INSERM UMR- 1048, Toulouse, France (A.N.-S., R.S.); Faculty of Medicine, Department of Biochemistry, University of Toulouse, Toulouse, France (A.N.-S., R.S.); and INSERM UMR- 1060, Université de Lyon, Cardiovasculaire, Métabolisme, Diabétologie, et Nutrition (CarMeN), INSA-Lyon, IMBL, Lyon, France (C.C., M.L.).

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http://dx.doi.org/10.1161/ATVBAHA.113.301468DOI Listing
December 2013

Genetic determination of plasma cholesterol efflux capacity is gender-specific and independent of HDL-cholesterol levels.

Arterioscler Thromb Vasc Biol 2013 Apr 31;33(4):822-8. Epub 2013 Jan 31.

INSERM UMRS 939, Hôpital de la Pitié, Pavillon Benjamin Delessert, 83, Boulevard de l'Hôpital, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1161/ATVBAHA.112.300979DOI Listing
April 2013

Functional characterization of novel variants in the CETP promoter and the LIPC gene in subjects with hyperalphalipoproteinemia.

Clin Chim Acta 2013 Feb 5;416:92-5. Epub 2012 Dec 5.

Hormonal and Metabolic Disorders Research Unit, Department of Medicine, Faculty of Medicine, Chulalongkorn University, and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Patumwan, Bangkok 10330, Thailand.

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http://dx.doi.org/10.1016/j.cca.2012.11.024DOI Listing
February 2013

Elevated CETP activity improves plasma cholesterol efflux capacity from human macrophages in women.

Arterioscler Thromb Vasc Biol 2012 Oct 16;32(10):2341-9. Epub 2012 Aug 16.

INSERM UMRS939, Hôpital de la Pitié, Pavillon Benjamin Delessert, 83, boulevard de l'Hôpital, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1161/ATVBAHA.112.252841DOI Listing
October 2012

Identification and characterization of new gain-of-function mutations in the PCSK9 gene responsible for autosomal dominant hypercholesterolemia.

Atherosclerosis 2012 Aug 17;223(2):394-400. Epub 2012 May 17.

Institut National de la Santé et de la Recherche Médicale, Inserm UMR698, Hemostasis, Bio-Engineering and Cardiovascular Remodelling, Hôpital Bichat-Claude Bernard, 46 Rue Henri Huchard, 75877 Paris Cedex 18, France.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.04.006DOI Listing
August 2012

Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome.

Nat Genet 2011 Dec 11;44(1):85-8. Epub 2011 Dec 11.

Département de Génétique, Unité INSERM U781, Université Paris Descartes, Sorbonne Paris Cité, Hôpital Necker Enfants Malades, Paris, France.

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http://dx.doi.org/10.1038/ng.1016DOI Listing
December 2011

Interleukin-6 protects human macrophages from cellular cholesterol accumulation and attenuates the proinflammatory response.

J Biol Chem 2011 Sep 8;286(35):30926-36. Epub 2011 Jul 8.

INSERM, UMR_S939, Dyslipidemia, Inflammation, and Atherosclerosis in Metabolic Diseases, and the ICAN Institute of CardioMetabolism and Nutrition F-75013 and the Université Pierre et Marie Curie Paris 06, UMR_S939, F-75005, Paris, France.

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http://dx.doi.org/10.1074/jbc.M111.264325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162452PMC
September 2011

Atheroprotective reverse cholesterol transport pathway is defective in familial hypercholesterolemia.

Arterioscler Thromb Vasc Biol 2011 Jul 28;31(7):1675-81. Epub 2011 Apr 28.

Institut National de la Santé et de la Recherche Médicale, UMRS 939, Hôpital de la Pitié, Paris, France.

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http://dx.doi.org/10.1161/ATVBAHA.111.227181DOI Listing
July 2011

CETP deficiency due to a novel mutation in the CETP gene promoter and its effect on cholesterol efflux and selective uptake into hepatocytes.

Atherosclerosis 2011 Jun 26;216(2):370-3. Epub 2011 Feb 26.

Endocrinology and Metabolism Unit, Department of Medicine, Faculty of Medicine, Chulalongkorn University, and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Patumwan, Bangkok 10330, Thailand.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.01.051DOI Listing
June 2011

Postprandial lipemia enhances the capacity of large HDL2 particles to mediate free cholesterol efflux via SR-BI and ABCG1 pathways in type IIB hyperlipidemia.

J Lipid Res 2010 Nov 16;51(11):3350-8. Epub 2010 Aug 16.

Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS939, Hôpital de la Pitié, Paris, France.

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http://dx.doi.org/10.1194/jlr.P009746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952576PMC
November 2010

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors.

Eur Heart J 2010 Jan 12;31(2):149-64. Epub 2009 Oct 12.

INSERM, UMR S939, Dyslipidemia, Inflammation and Atherosclerosis Research Unit, University Pierre and Marie Curie-Paris 6, Pavillon Benjamin Delessert, Hôpital de la Pitié, 83 Boulevard de l'Hôpital, Paris Cedex 13, France.

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http://dx.doi.org/10.1093/eurheartj/ehp399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806550PMC
January 2010

Torcetrapib differentially modulates the biological activities of HDL2 and HDL3 particles in the reverse cholesterol transport pathway.

Arterioscler Thromb Vasc Biol 2009 Feb 26;29(2):268-75. Epub 2008 Nov 26.

INSERM UMRS551, Hôpital de la Pitié, Paris, France.

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http://dx.doi.org/10.1161/ATVBAHA.108.179416DOI Listing
February 2009

Cellular SR-BI and ABCA1-mediated cholesterol efflux are gender-specific in healthy subjects.

J Lipid Res 2008 Mar 5;49(3):635-43. Epub 2007 Dec 5.

Institut National de la Santé et de la Recherche Médicale, UMR_S551, Dyslipoproteinemia and Atherosclerosis, Paris, France.

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http://dx.doi.org/10.1194/jlr.M700510-JLR200DOI Listing
March 2008

Inhibition of CETP by torcetrapib attenuates the atherogenicity of postprandial TG-rich lipoproteins in type IIB hyperlipidemia.

Arterioscler Thromb Vasc Biol 2008 Jan 19;28(1):148-54. Epub 2007 Oct 19.

INSERM Unité 551, Hôpital de la Pitié, Pavillon Benjamin Delessert, 83, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1161/ATVBAHA.107.151688DOI Listing
January 2008

Transcriptome profile of macrophages from atherosclerosis-sensitive and atherosclerosis-resistant mice.

Mamm Genome 2006 Mar 3;17(3):220-9. Epub 2006 Mar 3.

Department of Cell Biology, Cleveland Clinic Foundation, Ohio , 44195, USA.

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http://dx.doi.org/10.1007/s00335-005-0099-7DOI Listing
March 2006

Identification of the cAMP-responsive enhancer of the murine ABCA1 gene: requirement for CREB1 and STAT3/4 elements.

Arterioscler Thromb Vasc Biol 2006 Mar 22;26(3):527-33. Epub 2005 Dec 22.

Dept. of Cell Biology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1161/01.ATV.0000201042.00725.84DOI Listing
March 2006

Reevaluation of the role of the multidrug-resistant P-glycoprotein in cellular cholesterol homeostasis.

J Lipid Res 2006 Jan 7;47(1):51-8. Epub 2005 Oct 7.

Department of Cell Biology NC10, Cleveland Clinic Foundation, Cleveland, OH, USA.

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http://dx.doi.org/10.1194/jlr.M500255-JLR200DOI Listing
January 2006

Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study.

Hum Mol Genet 2005 Sep 27;14(18):2607-18. Epub 2005 Jul 27.

Institut National de la Santé et de la Recherche Médicale, INSERM Unité 551, Dyslipoproteinemia and Atherosclerosis, Paris Cedex, France.

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http://dx.doi.org/10.1093/hmg/ddi291DOI Listing
September 2005

Cyclosporin A traps ABCA1 at the plasma membrane and inhibits ABCA1-mediated lipid efflux to apolipoprotein A-I.

Arterioscler Thromb Vasc Biol 2004 Nov 9;24(11):2155-61. Epub 2004 Sep 9.

Department of Cell Biology NC10, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1161/01.ATV.0000144811.94581.52DOI Listing
November 2004

Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics.

Biochim Biophys Acta 2004 Jan;1676(1):41-50

Laboratory of Biochemical Genetics and Metabolism, The Rockefeller University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.bbaexp.2003.10.007DOI Listing
January 2004

Pharmacological modulation of cholesteryl ester transfer protein, a new therapeutic target in atherogenic dyslipidemia.

Pharmacol Ther 2004 Jan;101(1):17-38

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 551, "Dyslipoproteinemia and Atherosclerosis: Genetics, Metabolism and Therapy", Hôpital de la Pitié, 83 boulevard de l'Hôpital, 75651 Cedex 13, Paris, France.

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http://dx.doi.org/10.1016/j.pharmthera.2003.10.001DOI Listing
January 2004

ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I.

J Lipid Res 2004 Apr 1;45(4):635-44. Epub 2004 Jan 1.

Department of Cell Biology NC10, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1194/jlr.M300336-JLR200DOI Listing
April 2004

Action of ciprofibrate in type IIb hyperlipoproteinemia: modulation of the atherogenic lipoprotein phenotype and stimulation of high-density lipoprotein-mediated cellular cholesterol efflux.

J Clin Endocrinol Metab 2003 Aug;88(8):3738-46

Institut National de la Santé et de la Recherche Médicale Unité 551, Dyslipoproteinemia and Atherosclerosis, Hôpital de la Pitié, 75651 Paris, France.

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http://dx.doi.org/10.1210/jc.2003-030191DOI Listing
August 2003

Regulation of human CETP gene expression: role of SP1 and SP3 transcription factors at promoter sites -690, -629, and -37.

J Lipid Res 2003 Jul 1;44(7):1322-31. Epub 2003 May 1.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 551 "Dyslipoproteinemias and Atherosclerosis: Genetics, Metabolism and Therapy" , Hôpital de la Pitié, 83 boulevard de l'Hôpital, 75651 Paris, France.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M200425-JLR200
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http://dx.doi.org/10.1194/jlr.M200425-JLR200DOI Listing
July 2003

A CYP7A promoter binding factor site and Alu repeat in the distal promoter region are implicated in regulation of human CETP gene expression.

J Lipid Res 2003 May 16;44(5):902-10. Epub 2003 Feb 16.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 551, Dyslipoproteinemias and Atherosclerosis: Genetics, Metabolism and Therapy, Hôpital de la Pitié, 83 boulevard de l'Hôpital 75651 Paris, France.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M200423-JLR200
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http://dx.doi.org/10.1194/jlr.M200423-JLR200DOI Listing
May 2003

Atorvastatin reduces postprandial accumulation and cholesteryl ester transfer protein-mediated remodeling of triglyceride-rich lipoprotein subspecies in type IIb hyperlipidemia.

J Clin Endocrinol Metab 2002 Nov;87(11):4991-5000

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité 551, Dyslipoproteinemia and Atherosclerosis, Hôpital de la Pitié, Pavillon Benjamin Delessert, 83 boulevard de l'hôpital, 75651 Paris Cedex 13, France.

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http://dx.doi.org/10.1210/jc.2002-020298DOI Listing
November 2002

Cholesteryl ester flux from HDL to VLDL-1 is preferentially enhanced in type IIB hyperlipidemia in the postprandial state.

J Lipid Res 2002 Oct;43(10):1652-60

Institut National de la Santé et de la Recherche Médicale, INSERM Unité 551, Dyslipoproteinemia and Atherosclerosis, Hôpital de la Pitié, 75651 Paris, France.

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http://dx.doi.org/10.1194/jlr.m200135-jlr200DOI Listing
October 2002

Dose-dependent action of atorvastatin in type IIB hyperlipidemia: preferential and progressive reduction of atherogenic apoB-containing lipoprotein subclasses (VLDL-2, IDL, small dense LDL) and stimulation of cellular cholesterol efflux.

Atherosclerosis 2002 Aug;163(2):287-96

Institut National de la Santé et de la Recherche Médicale (INSERM Unité 551), Hôpital de la Pitié, Pavillon Benjamin Delessert, 83 Boulevard de l'Hôpital, 75651 Paris, Cedex 13, France.

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http://dx.doi.org/10.1016/s0021-9150(02)00037-0DOI Listing
August 2002

A novel cholesteryl ester transfer protein promoter polymorphism (-971G/A) associated with plasma high-density lipoprotein cholesterol levels. Interaction with the TaqIB and -629C/A polymorphisms.

Atherosclerosis 2002 Apr;161(2):269-79

Institut National de la Santé et de la Recherche Médicale, Hôpital de la Pitié, Unité 321 Lipoprotéines et Athérogénèse, Pavillon Benjamin Delessert, 83 Boulevard de l'Hôpital 75651 Paris 13, France.

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http://dx.doi.org/10.1016/s0021-9150(01)00641-4DOI Listing
April 2002