Publications by authors named "Wilfried Ellmeier"

70Publications

Histone deacetylases as targets in autoimmune and autoinflammatory diseases.

Adv Immunol 2020 15;147:1-59. Epub 2020 Jul 15.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/bs.ai.2020.06.001DOI Listing
July 2020

PP2A Phospho-Tyr Antibodies Are Not Specific for this Modification but Are Sensitive to Other PP2A Modifications Including Leu Methylation.

Cell Rep 2020 03;30(9):3171-3182.e6

Center for Medical Biochemistry, Max Perutz Labs, Medical University of Vienna, Dr. Bohr-Gasse 9, 1030 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.02.035DOI Listing
March 2020

The zinc-finger transcription factor MAZR regulates iNKT cell subset differentiation.

Cell Mol Life Sci 2019 Nov 7;76(21):4391-4404. Epub 2019 May 7.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

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http://dx.doi.org/10.1007/s00018-019-03119-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803753PMC
November 2019

Differential Requirement of Enhancers E8 and E8 in Cytotoxic Lineage T Cells and in Intestinal Intraepithelial Lymphocytes.

Front Immunol 2019 11;10:409. Epub 2019 Mar 11.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3389/fimmu.2019.00409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421288PMC
July 2020

Author Correction: Histone deacetylase function in CD4 T cells.

Nat Rev Immunol 2019 Apr;19(4):266

Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41577-019-0153-4DOI Listing
April 2019

NCOR1-a new player on the field of T cell development.

J Leukoc Biol 2018 12 17;104(6):1061-1068. Epub 2018 Aug 17.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/JLB.1RI0418-168RDOI Listing
December 2018

Histone deacetylase function in CD4 T cells.

Nat Rev Immunol 2018 10;18(10):617-634

Division of Cell and Developmental Biology, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41577-018-0037-zDOI Listing
October 2018

CXCL5 as Regulator of Neutrophil Function in Cutaneous Melanoma.

J Invest Dermatol 2019 01 4;139(1):186-194. Epub 2018 Oct 4.

Skin and Endothelium Research Division (SERD), Department of Dermatology, Medical University of Vienna, Vienna, Austria; Division of General Dermatology and Dermatooncology, Department of Dermatology, Medical University of Vienna, Vienna, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X183235
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http://dx.doi.org/10.1016/j.jid.2018.07.006DOI Listing
January 2019

The corepressor NCOR1 regulates the survival of single-positive thymocytes.

Sci Rep 2017 Nov 21;7(1):15928. Epub 2017 Nov 21.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria.

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http://dx.doi.org/10.1038/s41598-017-15918-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698297PMC
November 2017

Immunity meets metabolism and then they start talking.

FEBS Lett 2017 10;591(19):2957-2958

Division of Immunobiology, Institute of Immunology, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1002/1873-3468.12857DOI Listing
October 2017

A T cell-specific deletion of HDAC1 protects against experimental autoimmune encephalomyelitis.

J Autoimmun 2018 01 28;86:51-61. Epub 2017 Sep 28.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.09.008DOI Listing
January 2018

Distinct and Overlapping Functions of TEC Kinase and BTK in B Cell Receptor Signaling.

J Immunol 2017 04 8;198(8):3058-3068. Epub 2017 Mar 8.

Department of Pulmonary Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1601285DOI Listing
April 2017

The AMP analog AICAR modulates the Treg/Th17 axis through enhancement of fatty acid oxidation.

FASEB J 2016 11 4;30(11):3800-3809. Epub 2016 Aug 4.

Institute of Immunology, Center of Pathophysiology, Infectiology, and Immunology, Medical University of Vienna, Austria; and

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http://dx.doi.org/10.1096/fj.201600522RDOI Listing
November 2016

Acetylation of the Cd8 Locus by KAT6A Determines Memory T Cell Diversity.

Cell Rep 2016 09;16(12):3311-3321

The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.08.056DOI Listing
September 2016

Rapid multiplex analysis of lipid raft components with single-cell resolution.

Sci Signal 2015 Sep 22;8(395):rs11. Epub 2015 Sep 22.

Institute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Lazarettgasse 19, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1126/scisignal.aac5584DOI Listing
September 2015

MAZR and Runx Factors Synergistically Repress ThPOK during CD8+ T Cell Lineage Development.

J Immunol 2015 Sep 7;195(6):2879-87. Epub 2015 Aug 7.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria;

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http://dx.doi.org/10.4049/jimmunol.1500387DOI Listing
September 2015

Molecular control of CD4(+) T cell lineage plasticity and integrity.

Int Immunopharmacol 2015 Oct 9;28(2):813-7. Epub 2015 Apr 9.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Lazarettgasse 19, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.intimp.2015.03.050DOI Listing
October 2015

Distinct pathways regulate Syk protein activation downstream of immune tyrosine activation motif (ITAM) and hemITAM receptors in platelets.

J Biol Chem 2015 May 12;290(18):11557-68. Epub 2015 Mar 12.

From the Department of Physiology, Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, Pennsylvania 19140,

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http://dx.doi.org/10.1074/jbc.M114.629527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416859PMC
May 2015

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.

Mol Cell Biol 2015 May 9;35(10):1741-53. Epub 2015 Mar 9.

Biological Sciences and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey Sabanci University Nanotechnology Research and Application Center-SUNUM, Istanbul, Turkey

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http://dx.doi.org/10.1128/MCB.01475-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4405645PMC
May 2015

A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells.

J Leukoc Biol 2015 Apr 29;97(4):635-44. Epub 2014 Dec 29.

*Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Department of Medical Biochemistry, Max F. Perutz Laboratories, Vienna Biocenter, and Institute of Vascular Biology, Medical University of Vienna, Austria; Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan; and CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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http://dx.doi.org/10.1189/jlb.1HI1113-597RRDOI Listing
April 2015

HDAC1 controls CD8+ T cell homeostasis and antiviral response.

PLoS One 2014 21;9(10):e110576. Epub 2014 Oct 21.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110576PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4204873PMC
June 2015

The role of BTB-zinc finger transcription factors during T cell development and in the regulation of T cell-mediated immunity.

Curr Top Microbiol Immunol 2014 ;381:21-49

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090, Vienna, Austria,

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http://dx.doi.org/10.1007/82_2014_374DOI Listing
March 2015

Transcriptional control of CD4 and CD8 coreceptor expression during T cell development.

Cell Mol Life Sci 2013 Dec 21;70(23):4537-53. Epub 2013 Jun 21.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Lazarettgasse, 19, 1090, Vienna, Austria,

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http://dx.doi.org/10.1007/s00018-013-1393-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827898PMC
December 2013

The role of Tec family kinases in the regulation of T-helper-cell differentiation.

Int Rev Immunol 2012 Apr;31(2):133-54

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.3109/08830185.2012.664798DOI Listing
April 2012

Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells.

Proc Natl Acad Sci U S A 2011 Nov 24;108(45):18330-5. Epub 2011 Oct 24.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.1105835108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215065PMC
November 2011

Transcriptional and epigenetic regulation of CD4/CD8 lineage choice.

Adv Immunol 2011 ;110:71-110

Laboratory for Transcriptional Regulation, Research Center for Allergy and Immunology, RIKEN, Suehiro-cho, Turumi-ku, Yokohama, Kanagawa, Japan.

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http://dx.doi.org/10.1016/B978-0-12-387663-8.00003-XDOI Listing
November 2011

Central nervous system mast cells in peripheral inflammatory nociception.

Mol Pain 2011 Jun 3;7:42. Epub 2011 Jun 3.

Department of Neurophysiology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, 1090 Vienna, Austria.

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http://dx.doi.org/10.1186/1744-8069-7-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123586PMC
June 2011

RUNX transcription factor-mediated association of Cd4 and Cd8 enables coordinate gene regulation.

Immunity 2011 Mar;34(3):303-14

Molecular Pathogenesis Program, The Kimmel Center for Biology and Medicine of the Skirball Institute, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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http://dx.doi.org/10.1016/j.immuni.2011.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101577PMC
March 2011

Tec family kinases: regulation of FcεRI-mediated mast-cell activation.

FEBS J 2011 Jun 29;278(12):1990-2000. Epub 2011 Mar 29.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1111/j.1742-4658.2011.08073.xDOI Listing
June 2011

The protein tyrosine kinase Tec regulates a CD44highCD62L- Th17 subset.

J Immunol 2010 Nov 24;185(9):5111-9. Epub 2010 Sep 24.

Division of Immunobiology, Institute of Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.1001734DOI Listing
November 2010

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.

Nat Immunol 2010 May 11;11(5):442-8. Epub 2010 Apr 11.

Division of Immunobiology, Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/ni.1860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365445PMC
May 2010

The protein tyrosine kinase Tec regulates mast cell function.

Eur J Immunol 2009 Nov;39(11):3228-38

Division of Immunobiology, Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Austria.

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http://doi.wiley.com/10.1002/eji.200838839
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http://dx.doi.org/10.1002/eji.200838839DOI Listing
November 2009

The role of Tec family kinases in mononuclear phagocytes.

Crit Rev Immunol 2009 ;29(4):317-33

Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1615/critrevimmunol.v29.i4.30DOI Listing
September 2009

Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells.

BMC Genomics 2009 May 18;10:233. Epub 2009 May 18.

Department of Laboratory Medicine, Clinical Research Center, Karolinska Institutet, Karolinska University Hospital Huddinge, SE-14186 Huddinge, Sweden.

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http://dx.doi.org/10.1186/1471-2164-10-233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689280PMC
May 2009

Impaired T-cell development in the absence of Vav1 and Itk.

Eur J Immunol 2008 Dec;38(12):3530-42

Division of Immunobiology, Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/eji.200838388DOI Listing
December 2008

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells.

Proc Natl Acad Sci U S A 2008 Nov 12;105(46):17919-24. Epub 2008 Nov 12.

Division of Immunobiology, Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, A-1090 Vienna, Austria.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0805733105
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http://dx.doi.org/10.1073/pnas.0805733105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584723PMC
November 2008

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival.

J Immunol 2008 Jun;180(12):8048-56

Institute of Immunology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001193PMC
http://dx.doi.org/10.4049/jimmunol.180.12.8048DOI Listing
June 2008

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

Nat Immunol 2007 Oct 16;8(10):1049-59. Epub 2007 Sep 16.

Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/ni1512DOI Listing
October 2007

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.

Proc Natl Acad Sci U S A 2007 Aug 7;104(33):13283-8. Epub 2007 Aug 7.

Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 19, 1090 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.0702654104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940229PMC
August 2007

Regulation of dendritic cell differentiation and subset distribution by the zinc finger protein CTCF.

Immunol Lett 2007 Apr 8;109(2):165-74. Epub 2007 Mar 8.

Institute of Immunology, Medical University of Vienna, Lazarettgasse 19, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.imlet.2007.02.006DOI Listing
April 2007

The role of BTB domain-containing zinc finger proteins in T cell development and function.

Immunol Lett 2007 Jan 18;108(1):1-9. Epub 2006 Oct 18.

Institute of Immunology, Medical University of Vienna, Lazarettgasse 19, A-1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.imlet.2006.09.007DOI Listing
January 2007

CD8 T cell sensory adaptation dependent on TCR avidity for self-antigens.

J Immunol 2005 Dec;175(11):7388-97

Molecular Immunology Unit, Department of Immunology, Institut Pasteur, Paris, France.

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http://dx.doi.org/10.4049/jimmunol.175.11.7388DOI Listing
December 2005

Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development.

J Immunol 2005 Feb;174(3):1513-24

Institute of Immunology, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.174.3.1513DOI Listing
February 2005

The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development.

Adv Immunol 2004 ;83:55-89

RIKEN Research Center, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1016/S0065-2776(04)83002-5DOI Listing
June 2004

The role of Tec family kinases in myeloid cells.

Int Arch Allergy Immunol 2004 May 4;134(1):65-78. Epub 2004 May 4.

Medical University of Vienna, Institute of Immunology, Vienna, Austria.

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http://dx.doi.org/10.1159/000078339DOI Listing
May 2004

Tec regulates platelet activation by GPVI in the absence of Btk.

Blood 2003 Nov 3;102(10):3592-9. Epub 2003 Jul 3.

Department of Pharmacology, University of Oxford, Mansfield Rd, Oxford, OX1 3QT, United Kingdom.

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http://dx.doi.org/10.1182/blood-2003-04-1142DOI Listing
November 2003

Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation.

Nat Rev Immunol 2002 Dec;2(12):909-19

Division of Molecular Immunology, National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK.

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http://dx.doi.org/10.1038/nri952DOI Listing
December 2002

Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.

Immunity 2002 May;16(5):623-34

Institute of Immunology, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/s1074-7613(02)00309-6DOI Listing
May 2002