Wilfred F Dunnen

Wilfred F den Dunnen

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Wilfred F Dunnen

Wilfred F den Dunnen

Publications by authors named "Wilfred F den Dunnen"

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1PubMed Central Citations

ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation.

Cell Death Dis 2019 Sep 18;10(10):690. Epub 2019 Sep 18.

Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.1038/s41419-019-1934-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751174PMC
September 2019

VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.

Glia 2018 12 11;66(12):2645-2658. Epub 2018 Oct 11.

Department of Neuroscience, Section Medical Physiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://doi.wiley.com/10.1002/glia.23517
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http://dx.doi.org/10.1002/glia.23517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585704PMC
December 2018

Possible Obesogenic Effects of Bisphenols Accumulation in the Human Brain.

Sci Rep 2018 05 29;8(1):8186. Epub 2018 May 29.

Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-26498-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974368PMC
May 2018

IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma.

Oncotarget 2018 Mar 28;9(21):15721-15731. Epub 2018 Feb 28.

Department of Pathology and Medical Biology, Division of Pathology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.18632/oncotarget.24595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884659PMC
March 2018

Treatment of a thyrotropin-secreting pituitary adenoma (TSH-oma) with pasireotide LAR.

Clin Endocrinol (Oxf) 2017 12 18;87(6):877-879. Epub 2017 Aug 18.

Department of Endocrinology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/cen.13431DOI Listing
December 2017

Involvement of the cerebellum in Parkinson disease and dementia with Lewy bodies.

Ann Neurol 2017 Jun 2;81(6):898-903. Epub 2017 Jun 2.

Dr. Senckenberg Chronomedical Institute, J. W. Goethe University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1002/ana.24937DOI Listing
June 2017

On the distribution of intranuclear and cytoplasmic aggregates in the brainstem of patients with spinocerebellar ataxia type 2 and 3.

Brain Pathol 2017 05 2;27(3):345-355. Epub 2016 Aug 2.

Institute of Clinical Neuroanatomy, Department of Anatomy II, J.W. Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/bpa.12412DOI Listing
May 2017

Novel insights into vascularization patterns and angiogenic factors in glioblastoma subclasses.

J Neurooncol 2017 01 15;131(1):11-20. Epub 2016 Sep 15.

Department of Pathology and Medical Biology (Division of Pathology), University of Groningen, University Medical Center Groningen, HPC EA10, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s11060-016-2269-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5258811PMC
January 2017

Neurofibromatosis type 1 associated low grade gliomas: A comparison with sporadic low grade gliomas.

Crit Rev Oncol Hematol 2016 Aug 21;104:30-41. Epub 2016 May 21.

Department of Paediatrics, Beatrix Children's Hospital, Paediatric Oncology/Hematology Division, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2016.05.008DOI Listing
August 2016

Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma.

PLoS One 2015 23;10(3):e0122555. Epub 2015 Mar 23.

Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology division, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122555PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370756PMC
February 2016

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.

Hum Mol Genet 2015 Oct 27;24(19):5451-63. Epub 2015 Jul 27.

CNC-Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra 3004-517, Portugal, Faculty of Pharmacy, University of Coimbra, Coimbra 3000-548, Portugal,

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http://dx.doi.org/10.1093/hmg/ddv271DOI Listing
October 2015

Subclassification of newly diagnosed glioblastomas through an immunohistochemical approach.

PLoS One 2014 29;9(12):e115687. Epub 2014 Dec 29.

Department of Pathology and Medical Biology (Division of Pathology), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115687PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278713PMC
September 2015

Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis.

J Neuropathol Exp Neurol 2015 Jul;74(7):653-71

From the Instituto de Anatomía, Histología y Patología (MMG, RH, AO, NL, KV, CG, MCJ, FH, SR, MJ, EMR), Instituto de Neurociencias Clínicas (EO), Instituto de Obstetricia y Ginecología (FG), Universidad Austral de Chile, Valdivia, Chile; Facultad de Recursos Naturales (AO), Escuela de Medicina Veterinaria, Universidad Católica de Temuco, Araucania, Chile; Departments of Pediatric Neurology and Pediatrics (DAS), and Pathology and Medical Biology (WFAdD), University Medical Center, University of Groningen, Groningen, The Netherlands; Departamento de Biología Celular, Facultad de Ciencias, Universidad de Málaga, Málaga, Spain (AJJ, MDD-P, JMP-F); Department of Neurosurgery, Pediatric Neurosurgery Division, University of Utah, Salt Lake City, Utah (JPMA); and Department of Neurosurgery, Alpert Medical School at Brown University, Providence, Rhode Island (CEJ).

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http://dx.doi.org/10.1097/NEN.0000000000000203DOI Listing
July 2015

Peripheral nerve pathology in patients with severely affected complex regional pain syndrome type I.

Int J Rehabil Res 2015 Jun;38(2):121-30

aDepartment of Rehabilitation Medicine, Center for Rehabilitation Departments of bSurgery cOral and Maxillofacial Surgery dPathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1097/MRR.0000000000000096DOI Listing
June 2015

Hypoxia enhances migration and invasion in glioblastoma by promoting a mesenchymal shift mediated by the HIF1α-ZEB1 axis.

Cancer Lett 2015 Apr 12;359(1):107-16. Epub 2015 Jan 12.

Department of Medical Oncology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.01.010DOI Listing
April 2015

Recruitment of bone marrow derived cells during anti-angiogenic therapy in GBM: the potential of combination strategies.

Crit Rev Oncol Hematol 2014 Oct 10;92(1):38-48. Epub 2014 May 10.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2014.05.001DOI Listing
October 2014

Visual screening of muscle ultrasound images in children.

Ultrasound Med Biol 2014 Oct 9;40(10):2345-51. Epub 2014 Jul 9.

Department of Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ultrasmedbio.2014.03.027DOI Listing
October 2014

First patho-anatomical investigation of the brain of a SCA19 patient.

Neuropathol Appl Neurobiol 2014 Aug;40(5):640-4

Dr. Senckenbergisches Chronomedizinisches Institut, J.W. Goethe University, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1111/nan.12128DOI Listing
August 2014

Informed Decision-Making Regarding Amputation for Complex Regional Pain Syndrome Type I.

J Bone Joint Surg Am 2014 Jun 4;96(11):930-934. Epub 2014 Jun 4.

Department of Rehabilitation Medicine, Center for Rehabilitation (M.I.B., P.U.D., E.S., and J.H.G.), Department of Oral and Maxillofacial Surgery (P.U.D.), Department of Surgery (J.J.v.d.D.), and Department of Pathology and Medical Biology (W.F.d.D.), University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, the Netherlands.

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http://dx.doi.org/10.2106/JBJS.M.00788DOI Listing
June 2014

Association between methylation of the SLC6A4 promoter region in peripheral blood leukocytes and methylation in amygdala tissue.

Psychosom Med 2014 Apr;76(3):244-6

Departments of Psychiatry and Epidemiology, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE) Department of Epidemiology Department of Pathology and Medical Biology Department of Pediatrics, and Obstetrics and Gynaecology Department of Laboratory Medicine Department of Laboratory Medicine and Center for Liver Digestive and Metabolic Diseases University of Groningen University Medical Center Groningen Groningen, the Netherlands.

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http://pdfs.journals.lww.com/psychosomaticmedicine/2014/0400
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PSY.0000000000000048DOI Listing
April 2014

Anti-angiogenic therapy in pediatric brain tumors: an effective strategy?

Crit Rev Oncol Hematol 2014 Mar 10;89(3):418-32. Epub 2013 Oct 10.

Department of Pediatrics, Beatrix Children's Hospital, Pediatric Oncology/Hematology Division, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2013.09.005DOI Listing
March 2014

MGMT-STP27 methylation status as predictive marker for response to PCV in anaplastic Oligodendrogliomas and Oligoastrocytomas. A report from EORTC study 26951.

Clin Cancer Res 2013 Oct 15;19(19):5513-22. Epub 2013 Aug 15.

Authors' Affiliations: Departments of Neurology, Biostatistics, and Pathology, Neuro-Oncology Unit Erasmus MC, Rotterdam; AP-HP, Groupe Hospitalier Pitie Salpêtrière, Service de Neurologie 2 Mazarin and Université Pierre et Marie Curie-Paris 6, Centre de Recherche de l'Institut du Cerveau et de la Moelle Epinière (CRICM), Paris, France; Department of Pathology, UMCU, Utrecht; Department of Pathology, UMCG, Groningen; Department of Neurology, St. Elisabeth Hospital, Tilburg; Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen; Department of Pathology, Free University Medical Center, Amsterdam, the Netherlands; and European Organization for Research and Treatment of Cancer Data Center, Brussels, Belgium.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1157DOI Listing
October 2013

Commentary on special issue: CNS diseases and the immune system.

J Neuroimmune Pharmacol 2013 Sep 12;8(4):757-9. Epub 2013 Jun 12.

Department Immunobiology, Biomedical Primate Research Centre, Lange Kleiweg 161, 2288 GJ, Rijswijk, The Netherlands.

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http://dx.doi.org/10.1007/s11481-013-9486-0DOI Listing
September 2013

Neuropathological diagnostic considerations in hyperkinetic movement disorders.

Front Neurol 2013 14;4. Epub 2013 Feb 14.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen Groningen, Netherlands.

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http://dx.doi.org/10.3389/fneur.2013.00007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572425PMC
February 2013

Multiple VEGF family members are simultaneously expressed in ovarian cancer: a proposed model for bevacizumab resistance.

Curr Pharm Des 2012 ;18(25):3784-92

Department of Medical Oncology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.2174/138161212802002661DOI Listing
December 2012

Solvent-free tissue processing using supercritical carbon dioxide.

Histopathology 2012 Dec 21;61(6):1198-208. Epub 2012 Nov 21.

Department of Pathology and Medical Biology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2559.2012.04342.xDOI Listing
December 2012

Amputation for long-standing, therapy-resistant type-I complex regional pain syndrome.

J Bone Joint Surg Am 2012 Dec;94(24):2263-8

Departments of Rehabilitation Medicine, University Medical Center Groningen, University of Groningen, PO Box 30001, 9700 RB Groningen, the Netherlands.

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http://dx.doi.org/10.2106/JBJS.L.00532DOI Listing
December 2012

Genotype-phenotype correlations in spastic paraplegia type 7: a study in a large Dutch cohort.

Brain 2012 Oct 10;135(Pt 10):2994-3004. Epub 2012 Sep 10.

Department of Human Genetics, Institute for Genetic and Metabolic Disease, Radboud University Nijmegen Medical Centre, Nijmegen, 6500 HB, The Netherlands.

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http://dx.doi.org/10.1093/brain/aws224DOI Listing
October 2012

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion.

Neuro Oncol 2012 Sep 21;14(9):1125-35. Epub 2012 Jun 21.

Department of Pediatric Oncology/Hematology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, Groningen, the Netherlands.

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http://dx.doi.org/10.1093/neuonc/nos130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424207PMC
September 2012

Optimizing targeted cancer therapy: towards clinical application of systems biology approaches.

Crit Rev Oncol Hematol 2012 May;82(2):171-86

Beatrix Children's Hospital, Department of Pediatric Oncology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.critrevonc.2011.05.002DOI Listing
May 2012

An optimized protocol for the acute isolation of human microglia from autopsy brain samples.

Glia 2012 Jan 11;60(1):96-111. Epub 2011 Oct 11.

Section Medical Physiology, Department of Neuroscience, UMCG-RuG, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/glia.21251DOI Listing
January 2012

Therapy-resistant complex regional pain syndrome type I: to amputate or not?

J Bone Joint Surg Am 2011 Oct;93(19):1799-805

Department of Rehabilitation Medicine, University Medical Center Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.2106/JBJS.J.01329DOI Listing
October 2011

High acute myeloid leukemia derived VEGFA levels are associated with a specific vascular morphology in the leukemic bone marrow.

Cell Oncol (Dordr) 2011 Aug 6;34(4):289-96. Epub 2011 Apr 6.

Division of Pediatric Oncology/Hematology, Department of Pediatrics, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, the Netherlands.

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http://dx.doi.org/10.1007/s13402-011-0017-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162634PMC
August 2011

VEGF-SPECT with ¹¹¹In-bevacizumab in stage III/IV melanoma patients.

Eur J Cancer 2011 Jul 21;47(10):1595-602. Epub 2011 Mar 21.

Department of Medical Oncology, University Medical Center Groningen, Hanzeplein 1, Postbus 30.001, 9700 RB Groningen, Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2011.02.009DOI Listing
July 2011

Neuroependymal denudation is in progress in full-term human foetal spina bifida aperta.

Brain Pathol 2011 Mar;21(2):163-79

Departments of Pediatrics Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.

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http://dx.doi.org/10.1111/j.1750-3639.2010.00432.xDOI Listing
March 2011

Axonal inclusions in spinocerebellar ataxia type 3.

Acta Neuropathol 2010 Oct 16;120(4):449-60. Epub 2010 Jul 16.

Department of Pathology and Medical Biology, University Medical Centre Groningen, University of Groningen, 9713 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00401-010-0717-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923324PMC
October 2010

Tumor vessel biology in pediatric intracranial ependymoma.

J Neurosurg Pediatr 2010 Apr;5(4):335-41

Department of Neurosurgery, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.3171/2009.11.PEDS09260DOI Listing
April 2010

Porosity of the wall of a Neurolac nerve conduit hampers nerve regeneration.

Microsurgery 2009 ;29(6):473-8

Department of Plastic and Hand Surgery, Scheper Hospital, Boermarkeweg 60, Emmen, The Netherlands. com

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http://dx.doi.org/10.1002/micr.20642DOI Listing
December 2009

Myopathy in CRPS-I: disuse or neurogenic?

Eur J Pain 2009 Aug 31;13(7):731-6. Epub 2008 Oct 31.

Centre for Rehabilitation, University Medical Centre Groningen, University of Groningen, PO Box 30001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejpain.2008.09.006DOI Listing
August 2009

Kinome profiling in pediatric brain tumors as a new approach for target discovery.

Cancer Res 2009 Jul 30;69(14):5987-95. Epub 2009 Jun 30.

Department of Pediatric Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3660DOI Listing
July 2009

The angiopoietin 1/angiopoietin 2 balance as a prognostic marker in primary glioblastoma multiforme.

J Neurosurg 2009 Jan;110(1):147-55

Department of Pediatrics, Pediatric Oncology Division, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, The Netherlands.

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http://dx.doi.org/10.3171/2008.6.17612DOI Listing
January 2009

No disease in the brain of a 115-year-old woman.

Neurobiol Aging 2008 Aug 4;29(8):1127-32. Epub 2008 Jun 4.

Department of Pathology and Medical Biology, University Medical Centre Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2008.04.010DOI Listing
August 2008

Desmoplastic infantile ganglioglioma with a malignant course.

J Neurosurg Pediatr 2008 Jan;1(1):95-8

Departments of Neurosurgery, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.3171/PED-08/01/095DOI Listing
January 2008

Two related Dutch families with a clinically variable presentation of cardioskeletal myopathy caused by a novel S13F mutation in the desmin gene.

Eur J Med Genet 2007 Sep-Oct;50(5):355-66. Epub 2007 Jul 15.

Department of Genetics, University Medical Center Groningen, University of Groningen, Post Box 30001, 9700 RB Groningen, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S176972120700072
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http://dx.doi.org/10.1016/j.ejmg.2007.06.003DOI Listing
November 2007

A single chain (scFv425):sTRAIL fusion protein with specificity for the EGF receptor is effective in vitro but not in an in vivo brain tumor animal model.

J Neurooncol 2007 Jul 5. Epub 2007 Jul 5.

Department of Neurosurgery, University Medical Center Groningen, University Hospital Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands,

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http://dx.doi.org/10.1007/s11060-006-9322-yDOI Listing
July 2007

Anatomical alterations of the subthalamic nucleus in relation to age: a postmortem study.

Mov Disord 2005 Jul;20(7):893-8

Department of Pathology, University Hospital, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/mds.20417DOI Listing
July 2005

Neonatal loss of motor function in human spina bifida aperta.

Pediatrics 2004 Aug;114(2):427-34

Pediatric Neurology, Department of Pediatrics, University Hospital Groningen, PO Box 30.001, 9713 GZ Groningen, Netherlands.

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http://dx.doi.org/10.1542/peds.114.2.427DOI Listing
August 2004