Wilfred F J Van IJcken

Wilfred F J Van IJcken

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Wilfred F J Van IJcken

Wilfred F J Van IJcken

Publications by authors named "Wilfred F J Van IJcken"

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Characterization of the ferret TRB locus guided by V, D, J, and C gene expression analysis.

Immunogenetics 2019 Dec 3. Epub 2019 Dec 3.

Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00251-019-01142-9DOI Listing
December 2019

Late-onset phenotype associated with a homozygous GJC2 missense mutation in a Turkish family.

Parkinsonism Relat Disord 2019 Sep 31;66:228-231. Epub 2019 Jul 31.

Erasmus MC, University Medical Center, Rotterdam, the Netherlands, Department of Clinical Genetics. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.07.033DOI Listing
September 2019

Modeling the Pathological Long-Range Regulatory Effects of Human Structural Variation with Patient-Specific hiPSCs.

Cell Stem Cell 2019 May 11;24(5):736-752.e12. Epub 2019 Apr 11.

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany; Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany; Institute of Biomedicine and Biotechnology of Cantabria (IBBTEC), University of Cantabria, Cantabria, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.03.004DOI Listing
May 2019

Distinct Functions for Mammalian CLASP1 and -2 During Neurite and Axon Elongation.

Front Cell Neurosci 2019 29;13. Epub 2019 Jan 29.

Department of Cell Biology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, Netherlands.

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http://dx.doi.org/10.3389/fncel.2019.00005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373834PMC
January 2019

Epigenome analysis links gene regulatory elements in group 2 innate lymphocytes to asthma susceptibility.

J Allergy Clin Immunol 2018 12 2;142(6):1793-1807. Epub 2018 Mar 2.

Department of Pulmonary Medicine, Erasmus MC Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.12.1006DOI Listing
December 2018

Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease.

Gastroenterology 2018 07 28;155(1):118-129.e6. Epub 2018 Mar 28.

Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands; Neural Development and Gastroenterology Units, UCL Institute of Child Health, London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.03.034DOI Listing
July 2018

Colony-Stimulating Factor 1 Receptor (CSF1R) Regulates Microglia Density and Distribution, but Not Microglia Differentiation In Vivo.

Cell Rep 2018 07;24(5):1203-1217.e6

Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.113DOI Listing
July 2018

Large-Scale Expansion of Human iPSC-Derived Skeletal Muscle Cells for Disease Modeling and Cell-Based Therapeutic Strategies.

Stem Cell Reports 2018 06 3;10(6):1975-1990. Epub 2018 May 3.

Department of Clinical Genetics, Erasmus University Medical Center, 3015 GE Rotterdam, Netherlands; Department of Pediatrics, Erasmus University Medical Center, 3015 GE Rotterdam, Netherlands; Center for Lysosomal and Metabolic Diseases, Erasmus University Medical Center, 3015 GE Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993675PMC
June 2018

homozygous missense mutation associated with complicated hereditary spastic paraplegia.

Neurol Genet 2018 Apr 21;4(2):e223. Epub 2018 Mar 21.

Department of Psychiatry (C.G.B., S.R., F.M.S.d.V., S.A.K.) and Department of Clinical Genetics (C.G.B., M.Q., G.J.B., H.B.B., V.B.), Erasmus MC, Rotterdam, The Netherlands; Sackler School of Medicine (Z.A., A.F.-V.), Tel-Aviv University, Ramat-Aviv; Pediatric Neurology Unit (A.F.-V.), Dana Children's Hospital, Tel-Aviv Medical Center, Israel; Department of Molecular Pharmacology (I.E.K., A.M.D.), Groningen Research Institute of Pharmacy, University of Groningen, The Netherlands; Clalit Health Services (R.M.), Sharon-Shomron, Hadera District; Faculty of Health Science (R.M.), Ben-Gurion University of the Negev, Beer Sheva; Metabolic Disease Unit (H.M.), Meyer Children's Hospital, Rambam Health Care Campus and Technion Faculty of Medicine, Haifa; Nursing Research Unit (M.A.T.), Soroka University Medical Center and Faculty of Health Science, Ben Gurion University of the Negev, Be'er Sheva, Israel; Ecole Pratique des Hautes Etudes (G.S.), PSL Research University, Neurogenetics Laboratory; Institut du Cerveau et de la Moelle Epinière (G.S., A.B.), Sorbonne University, Pierre and Marie Curie University UMR_S1127, INSERM u1127, CNRS UMR5225, Paris, France; Center for Biomics (W.F.J.v.I.), Erasmus MC; Department of Epidemiology (M.W.V.) and Department of Radiology (M.W.V.), Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1212/NXG.0000000000000223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863690PMC
April 2018

SNPitty: An Intuitive Web Application for Interactive B-Allele Frequency and Copy Number Visualization of Next-Generation Sequencing Data.

J Mol Diagn 2018 03 2;20(2):166-176. Epub 2018 Jan 2.

Cancer Computational Biology Center, Erasmus MC, University Medical Center, Rotterdam, the Netherlands; Department of Urology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.11.011DOI Listing
March 2018

Unbiased Interrogation of 3D Genome Topology Using Chromosome Conformation Capture Coupled to High-Throughput Sequencing (4C-Seq).

Methods Mol Biol 2017 ;1507:199-220

Gene Regulation, Stem Cells andCancer Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain.

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http://dx.doi.org/10.1007/978-1-4939-6518-2_15DOI Listing
January 2018

PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation.

Cell Stem Cell 2017 05 9;20(5):689-705.e9. Epub 2017 Mar 9.

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Strasse 21, 50931 Cologne, Germany; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Joseph-Stelzmann-Strasse 26, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.02.004DOI Listing
May 2017

Comparison of Genome Sequences from Strains Isolated from Symptomatic and Asymptomatic Patients.

Front Microbiol 2016 27;7:1701. Epub 2016 Oct 27.

Division of Infectious Diseases and Immunology, Department of Pediatrics, Erasmus MC-Sophia Children's HospitalRotterdam, Netherlands; Department of Life Sciences, Erasmus University CollegeRotterdam, Netherlands.

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http://dx.doi.org/10.3389/fmicb.2016.01701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081376PMC
October 2016

Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length.

Forensic Sci Int Genet 2016 09 24;24:33-43. Epub 2016 May 24.

Department of Genetic Identification, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.fsigen.2016.05.014DOI Listing
September 2016

Overexpression of LMO2 causes aberrant human T-Cell development in vivo by three potentially distinct cellular mechanisms.

Exp Hematol 2016 09 11;44(9):838-849.e9. Epub 2016 Jun 11.

Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2016.06.002DOI Listing
September 2016

Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression.

Stem Cells Dev 2016 Apr 30;25(8):586-97. Epub 2016 Mar 30.

1 Nephrology and Transplantation, Department of Internal Medicine, Erasmus Medical Center , Rotterdam, the Netherlands .

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http://dx.doi.org/10.1089/scd.2015.0329DOI Listing
April 2016

Complex MAX Rearrangement in a Family With Malignant Pheochromocytoma, Renal Oncocytoma, and Erythrocytosis.

J Clin Endocrinol Metab 2016 Feb 15;101(2):453-60. Epub 2015 Dec 15.

Departments of Pathology (E.K., D.K., L.O., T.G.P., D.F.J.R., N.M.G.K., R.R.d.K., W.N.M.D.), Internal Medicine (R.A.F., W.W.d.H.), and Biomics (W.F.J.v.I.), Erasmus Medical Center Cancer Institute, University Medical Center, 3000 CA Rotterdam, The Netherlands; Departments of Clinical Genetics (B.H.E., R.A.O., A.d.K.), and Surgery (E.J.T.B., G.J.H.F.), Erasmus Medical Center Cancer Institute, University Medical Center, 3000 DR Rotterdam, The Netherlands; Department of Histopathology (T.G.P.), King's College Hospital, London, SE5 9RS, United Kingdom; Laboratory for Pathology (F.H.v.N.), Pathologisch Laboratorium Dordrecht, 3317 DA Dordrecht, The Netherlands; Division of Biomedical Genetics (R.B.v.d.L.), University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands; and Department of Pathology (R.R.d.K.), Reinier de Graaf Hospital, 2625 AD Delft, The Netherlands.

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http://dx.doi.org/10.1210/jc.2015-2592DOI Listing
February 2016

Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci.

Nucleic Acids Res 2016 Jan 17;44(1):175-86. Epub 2015 Sep 17.

Department of Immunology, Erasmus MC, University Medical Center, Wytemaweg 80, 3015 CN Rotterdam, The Netherlands

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http://dx.doi.org/10.1093/nar/gkv928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705691PMC
January 2016

The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.

Cell Stem Cell 2015 Sep 27;17(3):287-99. Epub 2015 Aug 27.

Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany; Medical Faculty, University of Frankfurt, 60590 Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870759PMC
September 2015

DC immunotherapy in HIV-1 infection induces a major blood transcriptome shift.

Vaccine 2015 Jun 24;33(25):2922-9. Epub 2015 Apr 24.

Department of Viroscience, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2015.04.047DOI Listing
June 2015

Endogenous WNT signals mediate BMP-induced and spontaneous differentiation of epiblast stem cells and human embryonic stem cells.

Stem Cell Reports 2015 Jan 24;4(1):114-128. Epub 2014 Dec 24.

Erasmus MC Stem Cell Institute, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands; Department of Cell Biology, Erasmus MC, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2014.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297870PMC
January 2015

Gene reprogramming in exercise-induced cardiac hypertrophy in swine: A transcriptional genomics approach.

J Mol Cell Cardiol 2014 Dec 22;77:168-74. Epub 2014 Oct 22.

Div. of Experimental Cardiology, Thoraxcenter, Cardiovascular research school COEUR, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2014.10.006DOI Listing
December 2014

Analysis of the transcriptome and immune function of monocytes during IFNα-based therapy in chronic HCV revealed induction of TLR7 responsiveness.

Antiviral Res 2014 Sep 9;109:116-24. Epub 2014 Jul 9.

Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Center Rotterdam, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542140018
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http://dx.doi.org/10.1016/j.antiviral.2014.06.020DOI Listing
September 2014

Gene expression analysis of peripheral cells for subclassification of pediatric inflammatory bowel disease in remission.

PLoS One 2013 18;8(11):e79549. Epub 2013 Nov 18.

Department of Paediatrics, Erasmus MC - Sophia Children's Hospital, Rotterdam, The Netherlands ; Department of Paediatric Gastroenterology, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079549PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832619PMC
July 2014

In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals.

Arch Toxicol 2014 Apr 5;88(4):1023-34. Epub 2014 Jan 5.

Center for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA, Bilthoven, The Netherlands.

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http://dx.doi.org/10.1007/s00204-013-1189-zDOI Listing
April 2014

Histone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2A.

PLoS Genet 2013 26;9(9):e1003719. Epub 2013 Sep 26.

Department of Biochemistry and Centre for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1371/journal.pgen.1003719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784504PMC
March 2014

Two independent transcription initiation codes overlap on vertebrate core promoters.

Nature 2014 Mar 16;507(7492):381-385. Epub 2014 Feb 16.

Institute of Clinical Sciences and MRC Clinical Sciences Center, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1038/nature12974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820030PMC
March 2014

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells.

Proc Natl Acad Sci U S A 2014 Jan 13;111(3):996-1001. Epub 2013 Dec 13.

Department of Cell Biology, Biophysical Genomics, Department of Cell Biology, Center for Biomics, Cancer Genomics Center, Erasmus Medical Center, 3015 GE, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1317788111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903193PMC
January 2014

Early divergence of Th1 and Th2 transcriptomes involves a small core response and sets of transiently expressed genes.

Eur J Immunol 2013 Apr 4;43(4):1074-84. Epub 2013 Mar 4.

Department of Virology, Erasmus MC, Rotterdam, The Netherlands; Theoretical Biology & Bioinformatics, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1002/eji.201242979DOI Listing
April 2013

Metabolic enzyme IMPDH is also a transcription factor regulated by cellular state.

Mol Cell 2012 Jul 31;47(1):133-9. Epub 2012 May 31.

Department of Biochemistry and Center for Biomedical Genetics, Erasmus University Medical Centre, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.molcel.2012.04.030DOI Listing
July 2012

Remodelers organize cellular chromatin by counteracting intrinsic histone-DNA sequence preferences in a class-specific manner.

Mol Cell Biol 2012 Feb 28;32(3):675-88. Epub 2011 Nov 28.

Department of Biochemistry and Center for Biomedical Genetics, Erasmus University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1128/MCB.06365-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266603PMC
February 2012

Left ventricular remodeling in swine after myocardial infarction: a transcriptional genomics approach.

Basic Res Cardiol 2011 Nov 5;106(6):1269-81. Epub 2011 Nov 5.

Division of Experimental Cardiology, Thoraxcenter, Erasmus MC, University Medical Center Rotterdam, P. O. Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00395-011-0229-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228945PMC
November 2011

Effective treatment of psoriasis with narrow-band UVB phototherapy is linked to suppression of the IFN and Th17 pathways.

J Invest Dermatol 2011 Jul 17;131(7):1547-58. Epub 2011 Mar 17.

Department of Dermatology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/jid.2011.53DOI Listing
July 2011