Wilbert H M Peters

Wilbert H M Peters

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Wilbert H M Peters

Wilbert H M Peters

Publications by authors named "Wilbert H M Peters"

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Shared heritability and functional enrichment across six solid cancers.

Authors:
Xia Jiang Hilary K Finucane Fredrick R Schumacher Stephanie L Schmit Jonathan P Tyrer Younghun Han Kyriaki Michailidou Corina Lesseur Karoline B Kuchenbaecker Joe Dennis David V Conti Graham Casey Mia M Gaudet Jeroen R Huyghe Demetrius Albanes Melinda C Aldrich Angeline S Andrew Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Natalia N Antonenkova Susanne M Arnold Kristan J Aronson Banu K Arun Elisa V Bandera Rosa B Barkardottir Daniel R Barnes Jyotsna Batra Matthias W Beckmann Javier Benitez Sara Benlloch Andrew Berchuck Sonja I Berndt Heike Bickeböller Stephanie A Bien Carl Blomqvist Stefania Boccia Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Hiltrud Brauch Hermann Brenner James D Brenton Mark N Brook Joan Brunet Hans Brunnström Daniel D Buchanan Barbara Burwinkel Ralf Butzow Gabriella Cadoni Trinidad Caldés Maria A Caligo Ian Campbell Peter T Campbell Géraldine Cancel-Tassin Lisa Cannon-Albright Daniele Campa Neil Caporaso André L Carvalho Andrew T Chan Jenny Chang-Claude Stephen J Chanock Chu Chen David C Christiani Kathleen B M Claes Frank Claessens Judith Clements J Margriet Collée Marcia Cruz Correa Fergus J Couch Angela Cox Julie M Cunningham Cezary Cybulski Kamila Czene Mary B Daly Anna deFazio Peter Devilee Orland Diez Manuela Gago-Dominguez Jenny L Donovan Thilo Dörk Eric J Duell Alison M Dunning Miriam Dwek Diana M Eccles Christopher K Edlund Digna R Velez Edwards Carolina Ellberg D Gareth Evans Peter A Fasching Robert L Ferris Triantafillos Liloglou Jane C Figueiredo Olivia Fletcher Renée T Fortner Florentia Fostira Silvia Franceschi Eitan Friedman Steven J Gallinger Patricia A Ganz Judy Garber José A García-Sáenz Simon A Gayther Graham G Giles Andrew K Godwin Mark S Goldberg David E Goldgar Ellen L Goode Marc T Goodman Gary Goodman Kjell Grankvist Mark H Greene Henrik Gronberg Jacek Gronwald Pascal Guénel Niclas Håkansson Per Hall Ute Hamann Freddie C Hamdy Robert J Hamilton Jochen Hampe Aage Haugen Florian Heitz Rolando Herrero Peter Hillemanns Michael Hoffmeister Estrid Høgdall Yun-Chul Hong John L Hopper Richard Houlston Peter J Hulick David J Hunter David G Huntsman Gregory Idos Evgeny N Imyanitov Sue Ann Ingles Claudine Isaacs Anna Jakubowska Paul James Mark A Jenkins Mattias Johansson Mikael Johansson Esther M John Amit D Joshi Radka Kaneva Beth Y Karlan Linda E Kelemen Tabea Kühl Kay-Tee Khaw Elza Khusnutdinova Adam S Kibel Lambertus A Kiemeney Jeri Kim Susanne K Kjaer Julia A Knight Manolis Kogevinas Zsofia Kote-Jarai Stella Koutros Vessela N Kristensen Jolanta Kupryjanczyk Martin Lacko Stephan Lam Diether Lambrechts Maria Teresa Landi Philip Lazarus Nhu D Le Eunjung Lee Flavio Lejbkowicz Heinz-Josef Lenz Goska Leslie Davor Lessel Jenny Lester Douglas A Levine Li Li Christopher I Li Annika Lindblom Noralane M Lindor Geoffrey Liu Fotios Loupakis Jan Lubiński Lovise Maehle Christiane Maier Arto Mannermaa Loic Le Marchand Sara Margolin Taymaa May Lesley McGuffog Alfons Meindl Pooja Middha Austin Miller Roger L Milne Robert J MacInnis Francesmary Modugno Marco Montagna Victor Moreno Kirsten B Moysich Lorelei Mucci Kenneth Muir Anna Marie Mulligan Katherine L Nathanson David E Neal Andrew R Ness Susan L Neuhausen Heli Nevanlinna Polly A Newcomb Lisa F Newcomb Finn Cilius Nielsen Liene Nikitina-Zake Børge G Nordestgaard Robert L Nussbaum Kenneth Offit Edith Olah Ali Amin Al Olama Olufunmilayo I Olopade Andrew F Olshan Håkan Olsson Ana Osorio Hardev Pandha Jong Y Park Nora Pashayan Michael T Parsons Tanja Pejovic Kathryn L Penney Wilbert H M Peters Catherine M Phelan Amanda I Phipps Dijana Plaseska-Karanfilska Miranda Pring Darya Prokofyeva Paolo Radice Kari Stefansson Susan J Ramus Leon Raskin Gad Rennert Hedy S Rennert Elizabeth J van Rensburg Marjorie J Riggan Harvey A Risch Angela Risch Monique J Roobol Barry S Rosenstein Mary Anne Rossing Kim De Ruyck Emmanouil Saloustros Dale P Sandler Elinor J Sawyer Matthew B Schabath Johanna Schleutker Marjanka K Schmidt V Wendy Setiawan Hongbing Shen Erin M Siegel Weiva Sieh Christian F Singer Martha L Slattery Karina Dalsgaard Sorensen Melissa C Southey Amanda B Spurdle Janet L Stanford Victoria L Stevens Sebastian Stintzing Jennifer Stone Karin Sundfeldt Rebecca Sutphen Anthony J Swerdlow Eloiza H Tajara Catherine M Tangen Adonina Tardon Jack A Taylor M Dawn Teare Manuel R Teixeira Mary Beth Terry Kathryn L Terry Stephen N Thibodeau Mads Thomassen Line Bjørge Marc Tischkowitz Amanda E Toland Diana Torres Paul A Townsend Ruth C Travis Nadine Tung Shelley S Tworoger Cornelia M Ulrich Nawaid Usmani Celine M Vachon Els Van Nieuwenhuysen Ana Vega Miguel Elías Aguado-Barrera Qin Wang Penelope M Webb Clarice R Weinberg Stephanie Weinstein Mark C Weissler Jeffrey N Weitzel Catharine M L West Emily White Alice S Whittemore H-Erich Wichmann Fredrik Wiklund Robert Winqvist Alicja Wolk Penella Woll Michael Woods Anna H Wu Xifeng Wu Drakoulis Yannoukakos Wei Zheng Shanbeh Zienolddiny Argyrios Ziogas Kristin K Zorn Jacqueline M Lane Richa Saxena Duncan Thomas Rayjean J Hung Brenda Diergaarde James McKay Ulrike Peters Li Hsu Montserrat García-Closas Rosalind A Eeles Georgia Chenevix-Trench Paul J Brennan Christopher A Haiman Jacques Simard Douglas F Easton Stephen B Gruber Paul D P Pharoah Alkes L Price Bogdan Pasaniuc Christopher I Amos Peter Kraft Sara Lindström

Nat Commun 2019 01 25;10(1):431. Epub 2019 Jan 25.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., Seattle, WA, 98109-1024, USA.

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http://dx.doi.org/10.1038/s41467-018-08054-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347624PMC
January 2019

Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers.

Int J Epidemiol 2018 Jul 28. Epub 2018 Jul 28.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1093/ije/dyy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659464PMC
July 2018

Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.

Lancet Oncol 2016 Oct 12;17(10):1363-1373. Epub 2016 Aug 12.

Institute of Human Genetics, and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052458PMC
http://dx.doi.org/10.1016/S1470-2045(16)30240-6DOI Listing
October 2016

Genetic polymorphisms in UDP-glucuronosyltransferase 1A6 and 1A7 and the risk for benign Warthin's tumors of the parotid gland.

Head Neck 2016 04 29;38 Suppl 1:E717-23. Epub 2015 Jul 29.

Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/hed.24077DOI Listing
April 2016

Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease.

Gastroenterology 2015 Oct 11;149(4):907-17.e7. Epub 2015 Jun 11.

Department of Human Genetics, Donders Centre for Neuroscience, Radboud university medical center, Nijmegen, The Netherlands; Department of Psychiatry, Donders Centre for Neuroscience, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1053/j.gastro.2015.06.002DOI Listing
October 2015

Allopurinol and 5-aminosalicylic acid influence thiopurine-induced hepatotoxicity in vitro.

Cell Biol Toxicol 2015 Jun 28;31(3):161-71. Epub 2015 Apr 28.

Department of Gastroenterology, Radboud University Nijmegen Medical Center, 455, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1007/s10565-015-9301-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441745PMC
June 2015

Genetic polymorphism 609C>T in NAD(P)H:quinone oxidoreductase 1 enhances the risk of proximal colon cancer.

J Hum Genet 2014 Jul 15;59(7):381-6. Epub 2014 May 15.

Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/jhg.2014.38DOI Listing
July 2014

Over-expression of COX-2 mRNA in colorectal cancer.

BMC Gastroenterol 2014 Jan 2;14. Epub 2014 Jan 2.

Department of Gastroenterology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.

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http://dx.doi.org/10.1186/1471-230X-14-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880419PMC
January 2014

Duodenal mucosal risk markers in patients with familial adenomatous polyposis: effects of celecoxib/ursodeoxycholic acid co-treatment and comparison with patient controls.

Orphanet J Rare Dis 2013 Nov 19;8:181. Epub 2013 Nov 19.

Department of Gastroenterology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/1750-1172-8-181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225600PMC
November 2013

Barrett associated MHC and FOXF1 variants also increase esophageal carcinoma risk.

Int J Cancer 2013 Oct 16;133(7):1751-5. Epub 2013 Apr 16.

Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/ijc.28160DOI Listing
October 2013

Disparities of conjugating protective enzyme activities in the colon of patients with adenomas and carcinomas.

World J Gastroenterol 2013 Sep;19(36):6020-5

Harald P Hoensch, Internal Medicine, Marien Hospital, D-64285 Darmstadt, Germany.

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http://dx.doi.org/10.3748/wjg.v19.i36.6020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785623PMC
September 2013

Dipyridamole augments the antiinflammatory response during human endotoxemia.

Crit Care 2011 30;15(6):R289. Epub 2011 Nov 30.

Department of Pharmacology-Toxicology, Radboud University Nijmegen Medical Center, Geert Grooteplein 10, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/cc10576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388652PMC
June 2013

Combined effect of genetic polymorphisms in phase I and II biotransformation enzymes on head and neck cancer risk.

Head Neck 2013 Jun 19;35(6):858-67. Epub 2012 Jun 19.

Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://doi.wiley.com/10.1002/hed.23054
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http://dx.doi.org/10.1002/hed.23054DOI Listing
June 2013

High enzyme activity UGT1A1 or low activity UGT1A8 and UGT2B4 genotypes increase esophageal cancer risk.

Int J Oncol 2012 Jun 22;40(6):1789-96. Epub 2012 Feb 22.

Department of Gastroenterology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3892/ijo.2012.1385DOI Listing
June 2012

A functional polymorphism in UGT1A1 related to hyperbilirubinemia is associated with a decreased risk for Crohn's disease.

J Crohns Colitis 2012 Jun 16;6(5):597-602. Epub 2011 Dec 16.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.crohns.2011.11.010DOI Listing
June 2012

EPHX1 polymorphisms do not modify esophageal carcinoma susceptibility in Dutch Caucasians.

Oncol Rep 2012 Jun 19;27(6):1710-6. Epub 2012 Mar 19.

Department of Gastroenterology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3892/or.2012.1734DOI Listing
June 2012

Infliximab exerts no direct hepatotoxic effect on HepG2 cells in vitro.

Dig Dis Sci 2012 Jun 26;57(6):1604-8. Epub 2012 Apr 26.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10620-012-2159-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358583PMC
June 2012

Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells.

Exp Cell Res 2012 Apr 14;318(7):819-27. Epub 2012 Feb 14.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.yexcr.2012.02.004DOI Listing
April 2012

Alkaline phosphatase for treatment of sepsis-induced acute kidney injury: a prospective randomized double-blind placebo-controlled trial.

Crit Care 2012 Jan 23;16(1):R14. Epub 2012 Jan 23.

Department of Intensive Care, Nijmegen Institute for Infection, Inflammation and Immunity, Radboud University Nijmegen Medical Center, Geert Grooteplein Zuid 10, Nijmegen, 6525 GA, The Netherlands.

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http://dx.doi.org/10.1186/cc11159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396250PMC
January 2012

Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury.

Crit Care 2011 6;15(1):R3. Epub 2011 Jan 6.

Department of Intensive Care Medicine, Radboud University Nijmegen Medical Center, Geert Grooteplein 10, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/cc9400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222030PMC
December 2011

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.

Authors:
Simon N Stacey Patrick Sulem Aslaug Jonasdottir Gisli Masson Julius Gudmundsson Daniel F Gudbjartsson Olafur T Magnusson Sigurjon A Gudjonsson Bardur Sigurgeirsson Kristin Thorisdottir Rafn Ragnarsson Kristrun R Benediktsdottir Bjørn A Nexø Anne Tjønneland Kim Overvad Peter Rudnai Eugene Gurzau Kvetoslava Koppova Kari Hemminki Cristina Corredera Victoria Fuentelsaz Pilar Grasa Sebastian Navarrete Fernando Fuertes Maria D García-Prats Enrique Sanambrosio Angeles Panadero Ana De Juan Almudena Garcia Fernando Rivera Dolores Planelles Virtudes Soriano Celia Requena Katja K Aben Michelle M van Rossum Ruben G H M Cremers Inge M van Oort Dick-Johan van Spronsen Jack A Schalken Wilbert H M Peters Brian T Helfand Jenny L Donovan Freddie C Hamdy Daniel Badescu Ovidiu Codreanu Mariana Jinga Irma E Csiki Vali Constantinescu Paula Badea Ioan N Mates Daniela E Dinu Adrian Constantin Dana Mates Sjofn Kristjansdottir Bjarni A Agnarsson Eirikur Jonsson Rosa B Barkardottir Gudmundur V Einarsson Fridbjorn Sigurdsson Pall H Moller Tryggvi Stefansson Trausti Valdimarsson Oskar T Johannsson Helgi Sigurdsson Thorvaldur Jonsson Jon G Jonasson Laufey Tryggvadottir Terri Rice Helen M Hansen Yuanyuan Xiao Daniel H Lachance Brian Patrick O Neill Matthew L Kosel Paul A Decker Gudmar Thorleifsson Hrefna Johannsdottir Hafdis T Helgadottir Asgeir Sigurdsson Valgerdur Steinthorsdottir Annika Lindblom Robert S Sandler Temitope O Keku Karina Banasik Torben Jørgensen Daniel R Witte Torben Hansen Oluf Pedersen Viorel Jinga David E Neal William J Catalona Margaret Wrensch John Wiencke Robert B Jenkins Eduardo Nagore Ulla Vogel Lambertus A Kiemeney Rajiv Kumar José I Mayordomo Jon H Olafsson Augustine Kong Unnur Thorsteinsdottir Thorunn Rafnar Kari Stefansson

Nat Genet 2011 Sep 25;43(11):1098-103. Epub 2011 Sep 25.

deCODE genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1038/ng.926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263694PMC
September 2011

A sex-specific association between a 15q25 variant and upper aerodigestive tract cancers.

Cancer Epidemiol Biomarkers Prev 2011 Apr 18;20(4):658-64. Epub 2011 Feb 18.

International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, 69372 Lyon CEDEX 08, France.

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http://dx.doi.org/10.1158/1055-9965.EPI-10-1008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070066PMC
April 2011

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.

Authors:
James D McKay Therese Truong Valerie Gaborieau Amelie Chabrier Shu-Chun Chuang Graham Byrnes David Zaridze Oxana Shangina Neonila Szeszenia-Dabrowska Jolanta Lissowska Peter Rudnai Eleonora Fabianova Alexandru Bucur Vladimir Bencko Ivana Holcatova Vladimir Janout Lenka Foretova Pagona Lagiou Dimitrios Trichopoulos Simone Benhamou Christine Bouchardy Wolfgang Ahrens Franco Merletti Lorenzo Richiardi Renato Talamini Luigi Barzan Kristina Kjaerheim Gary J Macfarlane Tatiana V Macfarlane Lorenzo Simonato Cristina Canova Antonio Agudo Xavier Castellsagué Ray Lowry David I Conway Patricia A McKinney Claire M Healy Mary E Toner Ariana Znaor Maria Paula Curado Sergio Koifman Ana Menezes Victor Wünsch-Filho José Eluf Neto Leticia Fernández Garrote Stefania Boccia Gabriella Cadoni Dario Arzani Andrew F Olshan Mark C Weissler William K Funkhouser Jingchun Luo Jan Lubiński Joanna Trubicka Marcin Lener Dorota Oszutowska Stephen M Schwartz Chu Chen Sherianne Fish David R Doody Joshua E Muscat Philip Lazarus Carla J Gallagher Shen-Chih Chang Zuo-Feng Zhang Qingyi Wei Erich M Sturgis Li-E Wang Silvia Franceschi Rolando Herrero Karl T Kelsey Michael D McClean Carmen J Marsit Heather H Nelson Marjorie Romkes Shama Buch Tomoko Nukui Shilong Zhong Martin Lacko Johannes J Manni Wilbert H M Peters Rayjean J Hung John McLaughlin Lars Vatten Inger Njølstad Gary E Goodman John K Field Triantafillos Liloglou Paolo Vineis Francoise Clavel-Chapelon Domenico Palli Rosario Tumino Vittorio Krogh Salvatore Panico Carlos A González J Ramón Quirós Carmen Martínez Carmen Navarro Eva Ardanaz Nerea Larrañaga Kay-Tee Khaw Timothy Key H Bas Bueno-de-Mesquita Petra H M Peeters Antonia Trichopoulou Jakob Linseisen Heiner Boeing Göran Hallmans Kim Overvad Anne Tjønneland Merethe Kumle Elio Riboli Kristjan Välk Tõnu Vooder Tõnu Voodern Andres Metspalu Diana Zelenika Anne Boland Marc Delepine Mario Foglio Doris Lechner Hélène Blanché Ivo G Gut Pilar Galan Simon Heath Mia Hashibe Richard B Hayes Paolo Boffetta Mark Lathrop Paul Brennan

PLoS Genet 2011 Mar 17;7(3):e1001333. Epub 2011 Mar 17.

International Agency for Research on Cancer (IARC), Lyon, France.

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http://pure.au.dk/ws/files/36381633/A_Genome_Wide_Associatio
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http://dx.plos.org/10.1371/journal.pgen.1001333
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http://dx.doi.org/10.1371/journal.pgen.1001333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060072PMC
March 2011

Genetic polymorphism in the conjugating enzyme UGT1A1 and the risk of head and neck cancer.

Int J Cancer 2010 Dec;127(12):2815-21

Department of Otorhinolaryngology, Head and Neck Surgery, Maastricht University Medical Center, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/ijc.25296DOI Listing
December 2010

The functional -765G→C polymorphism of the COX-2 gene may reduce the risk of developing crohn's disease.

PLoS One 2010 Nov 24;5(11):e15011. Epub 2010 Nov 24.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015011PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991351PMC
November 2010

Xanthine oxidase inhibition by allopurinol increases in vitro pyrazinamide-induced hepatotoxicity in HepG2 cells.

Drug Chem Toxicol 2010 Jul;33(3):325-8

Department of Pulmonary Diseases, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3109/01480540903449715DOI Listing
July 2010

Genetic polymorphisms in the tobacco smoke carcinogens detoxifying enzyme UGT1A7 and the risk of head and neck cancer.

Head Neck 2009 Oct;31(10):1274-81

Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/hed.21090DOI Listing
October 2009

COX-2 polymorphisms -765G-->C and -1195A-->G and colorectal cancer risk.

World J Gastroenterol 2009 Sep;15(36):4561-5

Department of Gastroenterology, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752001PMC
http://dx.doi.org/10.3748/wjg.15.4561DOI Listing
September 2009

GSTP1-1 in ovarian cyst fluid and disease outcome of patients with ovarian cancer.

Cancer Epidemiol Biomarkers Prev 2009 Aug;18(8):2176-81

Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1158/1055-9965.EPI-09-0098DOI Listing
August 2009

Genetic polymorphisms in UDP-glucuronosyltransferase 1A6 are not associated with NSAIDs-related peptic ulcer haemorrhage.

Drug Metab Lett 2009 Aug;3(3):199-204

Department of Gastroenterology & Hepatology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands.

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August 2009

COX-2 polymorphisms and the risk for head and neck cancer in white patients.

Head Neck 2009 Jul;31(7):938-43

Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/hed.21058DOI Listing
July 2009

COX-2 polymorphisms in patients with familial adenomatous polyposis.

Oncol Res 2009 ;17(8):347-51

Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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July 2009

Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno- or squamous cell carcinoma.

World J Gastroenterol 2009 Jul;15(28):3493-7

Department of Gastroenterology, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715974PMC
http://dx.doi.org/10.3748/wjg.15.3493DOI Listing
July 2009

Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.

Pharmacology 2009 5;83(4):237-42. Epub 2009 Mar 5.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1159/000205824DOI Listing
June 2009

Inflammation-induced hepatotoxicity in humans.

Shock 2009 Feb;31(2):151-6

Departments of Pharmacology-Toxicology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/SHK.0b013e31818335ffDOI Listing
February 2009

Alkaline phosphatase treatment improves renal function in severe sepsis or septic shock patients.

Crit Care Med 2009 Feb;37(2):417-23, e1

Department of Pharmacology and Toxicology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/CCM.0b013e31819598afDOI Listing
February 2009

Genetic polymorphisms of smoking-related carcinogen detoxifying enzymes and head and neck cancer susceptibility.

Anticancer Res 2009 Feb;29(2):753-61

Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Maastricht, P. Debyelaan 25, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands.

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February 2009

HELLP syndrome is associated with an increased inflammatory response, which may be inhibited by administration of prednisolone.

Hypertens Pregnancy 2008 ;27(3):253-65

Department of Perinatology and Gynaecology, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1080/10641950802174953DOI Listing
November 2008

Microsomal epoxide hydrolase genotypes and the risk for head and neck cancer.

Head Neck 2008 Jul;30(7):836-44

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Maastricht, Maastricht, The Netherlands.

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http://dx.doi.org/10.1002/hed.20781DOI Listing
July 2008

Prognostic value of free plasma homocysteine levels in patients hospitalized with acute coronary syndrome.

Am J Cardiol 2008 Jul 28;102(2):135-9. Epub 2008 May 28.

Department of Gastroenterology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.amjcard.2008.03.022DOI Listing
July 2008

Isoniazid and its toxic metabolite hydrazine induce in vitro pyrazinamide toxicity.

Int J Antimicrob Agents 2008 Jun 21;31(6):577-80. Epub 2008 Mar 21.

Department of Pulmonary Diseases, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ijantimicag.2008.01.022DOI Listing
June 2008

The transient increase of oxidative stress during normal pregnancy is higher and persists after delivery in women with pre-eclampsia.

Eur J Obstet Gynecol Reprod Biol 2008 May 10;138(1):39-44. Epub 2007 Sep 10.

Department of Gastroenterology, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ejogrb.2007.08.005DOI Listing
May 2008

The I,105V polymorphism in glutathione S-transferase P1, parental smoking and the risk for nonsyndromic cleft lip with or without cleft palate.

Eur J Hum Genet 2008 Mar 9;16(3):358-66. Epub 2008 Jan 9.

Department of Epidemiology and Biostatistics, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/sj.ejhg.5201973DOI Listing
March 2008

Short-term beneficial effects of methylene blue on kidney damage in septic shock patients.

Intensive Care Med 2008 Feb 10;34(2):350-4. Epub 2007 Oct 10.

Radboud University, Nijmegen Medical Centre, Department of Pharmacology and Toxicology, Nijmegen Center for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00134-007-0867-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2228379PMC
February 2008

Chromosomal and methylation alterations in sporadic and familial adenomatous polyposis-related duodenal carcinomas.

Mod Pathol 2007 Dec 14;20(12):1253-62. Epub 2007 Sep 14.

Department of Gastroenterology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/modpathol.3800952DOI Listing
December 2007

Liver manipulation causes hepatocyte injury and precedes systemic inflammation in patients undergoing liver resection.

World J Surg 2007 Oct;31(10):2033-8

Department of Surgery, University Hospital Maastricht and Nutrition and Toxicology Research Institute (NUTRIM), Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00268-007-9182-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039834PMC
October 2007

Susceptibility to pre-eclampsia is associated with multiple genetic polymorphisms in maternal biotransformation enzymes.

Gynecol Obstet Invest 2007 13;63(4):209-13. Epub 2006 Dec 13.

Department of Obstetrics and Gynaecology, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1159/000097987DOI Listing
June 2007

Genistein protects human mammary epithelial cells from benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide and 4-hydroxy-2-nonenal genotoxicity by modulating the glutathione/glutathione S-transferase system.

Carcinogenesis 2007 Mar 25;28(3):738-48. Epub 2006 Oct 25.

Department of Nutritional Toxicology, Institute for Nutrition, Friedrich-Schiller University Jena, Dornburger Strasse 25, 07743 Jena, Germany.

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http://dx.doi.org/10.1093/carcin/bgl180DOI Listing
March 2007

No evidence for oxidative stress in patients on home parenteral nutrition.

Clin Nutr 2006 Dec 14;25(6):939-48. Epub 2006 Jun 14.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S026156140600087
Publisher Site
http://dx.doi.org/10.1016/j.clnu.2006.05.001DOI Listing
December 2006

Loss of extracellular E-cadherin in the normal mucosa of duodenum and colon of patients with familial adenomatous polyposis.

Hum Pathol 2006 Nov 10;37(11):1389-99. Epub 2006 Aug 10.

Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.humpath.2006.05.018DOI Listing
November 2006

Short report: Severe Plasmodium falciparum malaria in Cameroon: associated with the glutathione S-transferase M1 null genotype.

Am J Trop Med Hyg 2006 Nov;75(5):827-9

Department of Pharmacology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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November 2006

Proteomic inventory of "anchorless" proteins on the colon adenocarcinoma cell surface.

Biochim Biophys Acta 2006 Oct 12;1764(10):1607-17. Epub 2006 Sep 12.

Department of Clinical Chemistry, 441, Radboud University Nijmegen-Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.bbapap.2006.09.002DOI Listing
October 2006

Assessment of oxidative stress in chronic pancreatitis patients.

World J Gastroenterol 2006 Sep;12(35):5705-10

Department of Gastroenterology, Radboud University Nijmegen Medical Centre, PO Box 9101, Nijmegen 6500 HB, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088174PMC
http://dx.doi.org/10.3748/wjg.v12.i35.5705DOI Listing
September 2006

Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury.

Clin J Am Soc Nephrol 2006 Jul 8;1(4):853-62. Epub 2006 Jun 8.

Department of Pharmacology and Toxicology (149), Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.2215/CJN.00490206DOI Listing
July 2006

A longitudinal study of antioxidant status during uncomplicated and hypertensive pregnancies.

Acta Obstet Gynecol Scand 2006 ;85(2):148-55

Department of Obstetrics & Gynaecology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1080/00016340500345832DOI Listing
April 2006

Low detoxification capacity in the ileal pouch mucosa of patients with ulcerative colitis.

Inflamm Bowel Dis 2006 Feb;12(2):112-6

Department of Gastroenterology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1097/01.MIB.0000199222.50465.4fDOI Listing
February 2006

Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.

Mutat Res 2006 Jan 21;593(1-2):39-49. Epub 2005 Jul 21.

Department of Gastroenterology, University Medical Centre, St. Radboud, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.mrfmmm.2005.06.018DOI Listing
January 2006

Paraoxonase 1-192Q allele is a risk factor for idiopathic chronic pancreatitis.

Mol Diagn 2005 ;9(1):9-15

Department of Medicine, Division of Gastroenterology and Hepatology, Radboud University Medical Centre, Nijmegen, The Netherlands.

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October 2005

N-acetyl-transferase phenotype and risk for preeclampsia.

Am J Obstet Gynecol 2005 Sep;193(3 Pt 1):797-802

Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ajog.2005.01.012DOI Listing
September 2005

High oxygen radical production in patients with sporadic colorectal cancer.

Free Radic Biol Med 2005 Jul 31;39(2):182-7. Epub 2005 Mar 31.

Department of Gastroenterology, University Medical Center St. Radboud, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.freeradbiomed.2005.03.003DOI Listing
July 2005

Small increases in the urinary excretion of glutathione S-transferase A1 and P1 after cardiac surgery are not associated with clinically relevant renal injury.

Intensive Care Med 2005 May 6;31(5):664-7. Epub 2005 Apr 6.

Department of Intensive Care Medicine (519), University Medical Centre St. Radboud, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s00134-005-2608-2DOI Listing
May 2005

No association between genetic polymorphisms in NAD(P)H oxidase p22phox and paraoxonase 1 and colorectal cancer risk.

Anticancer Res 2005 Mar-Apr;25(2B):1465-70

Department of Gastroenterology, University Medical Centre St Radboud, 6500 HB Nijmegen, The Netherlands.

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May 2005

Maternal antioxidant concentrations after uncomplicated pregnancies.

Free Radic Res 2005 Jan;39(1):95-103

Department of Obstetrics & Gynecology, University Medical Center Nijmegen, The Netherlands.

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January 2005

Low plasma levels of oxidized low density lipoprotein in preeclampsia.

Acta Obstet Gynecol Scand 2004 Dec;83(12):1173-7

Department of Gastroenterology, University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/j.0001-6349.2004.00539.xDOI Listing
December 2004

Habitual consumption of fruits and vegetables: associations with human rectal glutathione S-transferase.

Carcinogenesis 2004 Nov 29;25(11):2135-42. Epub 2004 Jul 29.

Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.

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http://dx.doi.org/10.1093/carcin/bgh238DOI Listing
November 2004

The Tyr113His polymorphism in exon 3 of the microsomal epoxide hydrolase gene is a risk factor for perinatal mortality.

Acta Obstet Gynecol Scand 2004 Nov;83(11):1056-60

Department of Gastroenterology, University Medical Center Nijmegen, the Netherlands.

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http://dx.doi.org/10.1111/j.0001-6349.2004.00455.xDOI Listing
November 2004

Association of aspirin use with vitamin B12 deficiency (results of the BACH study).

Am J Cardiol 2004 Oct;94(7):975-7

Department of Gastroenterology, Heartcenter, University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.amjcard.2004.06.047DOI Listing
October 2004

Vitamin B12 status and its association with Helicobacter pylori infection in alcohol dependent patients.

J Nutr Sci Vitaminol (Tokyo) 2004 Oct;50(5):305-8

Department of Gastroenterology, University Medical Center St Radboud, Nijmegen, The Netherlands.

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October 2004

Effects of dietary anticarcinogens and nonsteroidal anti-inflammatory drugs on rat gastrointestinal UDP-glucuronosyltransferases.

Anticancer Res 2004 Mar-Apr;24(2B):843-9

Department of Gastroenterology, University Medical Centre St Radboud, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.

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July 2004

Functional polymorphisms of UDP-glucuronosyltransferases 1A1, 1A6 and 1A8 are not involved in chronic pancreatitis.

Pharmacogenetics 2004 Jun;14(6):351-7

Department of Medicine, Division of Gastroenterology and Hepatology, University Medical Centre St Radboud, Nijmegen, The Netherlands.

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June 2004

Genetic polymorphisms in alcohol-metabolizing enzymes and chronic pancreatitis.

Alcohol Alcohol 2004 Jan-Feb;39(1):20-4

Department of Medicine, University Medical Centre St Radboud, Nijmegen, The Netherlands.

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http://alcalc.oxfordjournals.org/content/alcalc/39/1/20.full
Web Search
http://dx.doi.org/10.1093/alcalc/agh001DOI Listing
April 2004

Umbilical glutathione levels are higher after vaginal birth than after cesarean section.

J Perinat Med 2003 ;31(6):520-2

Department of Gastroenterology, University Medical Centre Nijmegen, The Netherlands.

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http://dx.doi.org/10.1515/JPM.2003.079DOI Listing
April 2004

Thiol status and antioxidant capacity in women with a history of severe pre-eclampsia.

BJOG 2004 Mar;111(3):207-12

Department of Gastroenterology, University Medical Center Nijmegen, The Netherlands.

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March 2004

Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate.

Carcinogenesis 2003 Oct 1;24(10):1637-44. Epub 2003 Aug 1.

Department of Nutritional Toxicology, Institute for Nutrition, Friedrich-Schiller-University, Dornburger Strasse 25, D-07743 Jena, Germany.

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http://dx.doi.org/10.1093/carcin/bgg122DOI Listing
October 2003