Publications by authors named "Werner Muller"

100Publications

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor.

Biomater Sci 2020 Dec 14;8(23):6603-6610. Epub 2020 Oct 14.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.1039/d0bm01244kDOI Listing
December 2020

Biomimetic Alginate/Gelatin Cross-Linked Hydrogels Supplemented with Polyphosphate for Wound Healing Applications.

Molecules 2020 Nov 9;25(21). Epub 2020 Nov 9.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.

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http://dx.doi.org/10.3390/molecules25215210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7664853PMC
November 2020

Amplified morphogenetic and bone forming activity of amorphous versus crystalline calcium phosphate/polyphosphate.

Acta Biomater 2020 Dec 17;118:233-247. Epub 2020 Oct 17.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, GERMANY.

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http://dx.doi.org/10.1016/j.actbio.2020.10.023DOI Listing
December 2020

Nanoparticle-directed and ionically forced polyphosphate coacervation: a versatile and reversible core-shell system for drug delivery.

Sci Rep 2020 10 13;10(1):17147. Epub 2020 Oct 13.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany.

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http://dx.doi.org/10.1038/s41598-020-73100-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555899PMC
October 2020

The inorganic polymer, polyphosphate, blocks binding of SARS-CoV-2 spike protein to ACE2 receptor at physiological concentrations.

Biochem Pharmacol 2020 Dec 6;182:114215. Epub 2020 Sep 6.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2020.114215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474874PMC
December 2020

The Generation of an Engineered Interleukin-10 Protein With Improved Stability and Biological Function.

Front Immunol 2020 11;11:1794. Epub 2020 Aug 11.

Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2020.01794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431522PMC
August 2020

Investigating the importance of B cells and antibodies during Trichuris muris infection using the IgMi mouse.

J Mol Med (Berl) 2020 Sep 10;98(9):1301-1317. Epub 2020 Aug 10.

Division of Infection, Immunity and Respiratory Medicine, Lydia Becker Institute for Immunology, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1007/s00109-020-01954-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7447682PMC
September 2020

Azacoccones F-H, new flavipin-derived alkaloids from an endophytic fungus Epicoccum nigrum MK214079.

Fitoterapia 2020 Oct 31;146:104698. Epub 2020 Jul 31.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Universitaetsstrasse 1, Geb. 26.23, 40225 Duesseldorf, Germany; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2020.104698DOI Listing
October 2020

wIRA-heating of piglet skin and subcutis : proof of accordance with ESHO criteria for superficial hyperthermia.

Int J Hyperthermia 2020 ;37(1):887-896

Department of Radiation Oncology, University Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1080/02656736.2020.1792562DOI Listing
January 2020

A physiologically active interpenetrating collagen network that supports growth and migration of epidermal keratinocytes: zinc-polyP nanoparticles integrated into compressed collagen.

J Mater Chem B 2020 07;8(27):5892-5902

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.1039/d0tb01240hDOI Listing
July 2020

Sesterterpenes and macrolide derivatives from the endophytic fungus Aplosporella javeedii.

Fitoterapia 2020 Oct 6;146:104652. Epub 2020 Jun 6.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany; Hubei Key Laboratory of Natural Products Research and Development, College of Biological and Pharmaceutical Sciences, China Three Gorges University, Yichang 443002, China. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2020.104652DOI Listing
October 2020

Amorphous Polyphosphate and Ca-Carbonate Nanoparticles Improve the Self-Healing Properties of both Technical and Medical Cements.

Biotechnol J 2020 Jun 4:e2000101. Epub 2020 Jun 4.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, Mainz, 55128, Germany.

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http://dx.doi.org/10.1002/biot.202000101DOI Listing
June 2020

Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors: a new toolbox to study the role of IL-1 in health and disease.

J Mol Med (Berl) 2020 07 29;98(7):923-930. Epub 2020 May 29.

Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, Building 308A, 55131, Mainz, Germany.

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http://dx.doi.org/10.1007/s00109-020-01928-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343756PMC
July 2020

Self-Healing Properties of Bioinspired Amorphous CaCO/Polyphosphate-Supplemented Cement.

Molecules 2020 May 19;25(10). Epub 2020 May 19.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.3390/molecules25102360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7287741PMC
May 2020

Polyketide Derivatives from Mangrove Derived Endophytic Fungus .

Mar Drugs 2020 Feb 23;18(2). Epub 2020 Feb 23.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University Duesseldorf, 40225 Duesseldorf, Germany.

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http://dx.doi.org/10.3390/md18020129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7073511PMC
February 2020

Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017.

Eur J Med Chem 2020 Apr 19;191:112159. Epub 2020 Feb 19.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225, Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2020.112159DOI Listing
April 2020

Functional omics analyses reveal only minor effects of microRNAs on human somatic stem cell differentiation.

Sci Rep 2020 02 24;10(1):3284. Epub 2020 Feb 24.

Institute for Transplantation Diagnostics and Cell Therapeutics, University Hospital Düsseldorf, Moorenstr. 5, Düsseldorf, Germany.

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http://dx.doi.org/10.1038/s41598-020-60065-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7040006PMC
February 2020

A synthetic biology approach for the fabrication of functional (fluorescent magnetic) bioorganic-inorganic hybrid materials in sponge primmorphs.

Biotechnol Bioeng 2020 06 28;117(6):1789-1804. Epub 2020 Feb 28.

Institute of Physiological Chemistry, University Medical Center, Johannes Gutenberg-University, Mainz, Germany.

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http://dx.doi.org/10.1002/bit.27310DOI Listing
June 2020

Multicolor 3D Printing of Complex Intracranial Tumors in Neurosurgery.

J Vis Exp 2020 01 11(155). Epub 2020 Jan 11.

Department of Neurosurgery, University Medical Center of the Johannes Gutenberg University Mainz, Germany.

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http://dx.doi.org/10.3791/60471DOI Listing
January 2020

A design criterion for symmetric model discrimination based on flexible nominal sets.

Biom J 2020 07 20;62(4):1090-1104. Epub 2020 Jan 20.

Department of Applied Statistics, Johannes Kepler University Linz, Linz, Austria.

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http://dx.doi.org/10.1002/bimj.201900074DOI Listing
July 2020

The Essential Role Played by B Cells in Supporting Protective Immunity Against Infection Is by Controlling the Th1/Th2 Balance in the Mesenteric Lymph Nodes and Depends on Host Genetic Background.

Front Immunol 2019 10;10:2842. Epub 2019 Dec 10.

Division of Infection, Immunity and Respiratory Medicine, Lydia Becker Institute for Immunology, The University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2019.02842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915098PMC
November 2020

Inorganic Polyphosphates As Storage for and Generator of Metabolic Energy in the Extracellular Matrix.

Chem Rev 2019 12 18;119(24):12337-12374. Epub 2019 Nov 18.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry , University Medical Center of the Johannes Gutenberg University , Duesbergweg 6 , D-55128 Mainz , Germany.

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http://dx.doi.org/10.1021/acs.chemrev.9b00460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6935868PMC
December 2019

Polyphosphate, the physiological metabolic fuel for corneal cells: a potential biomaterial for ocular surface repair.

Biomater Sci 2019 Dec 31;7(12):5506-5515. Epub 2019 Oct 31.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.1039/c9bm01289cDOI Listing
December 2019

Cuprous oxide nanoparticles reduces hypertrophic scarring by inducing fibroblast apoptosis.

Int J Nanomedicine 2019 30;14:5989-6000. Epub 2019 Jul 30.

Department of Burn Surgery, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of China.

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http://dx.doi.org/10.2147/IJN.S196794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680085PMC
November 2019

Brominated Azaphilones from the Sponge-Associated Fungus Strain 4.14.6a.

J Nat Prod 2019 08 30;82(8):2159-2166. Epub 2019 Jul 30.

Institute of Pharmaceutical Biology and Biotechnology , Heinrich-Heine-Universität Düsseldorf , Universitätsstrasse 1 , 40225 Düsseldorf , Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00151DOI Listing
August 2019

Cyclic heptapeptides from the soil-derived fungus Clonostachys rosea.

Bioorg Med Chem 2019 09 12;27(17):3954-3959. Epub 2019 Jul 12.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1016/j.bmc.2019.07.025DOI Listing
September 2019

Transformation of Construction Cement to a Self-Healing Hybrid Binder.

Int J Mol Sci 2019 Jun 17;20(12). Epub 2019 Jun 17.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55,128 Mainz, Germany.

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http://dx.doi.org/10.3390/ijms20122948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627329PMC
June 2019

Dithiodiketopiperazine derivatives from endophytic fungi and .

Nat Prod Res 2019 Jun 18:1-9. Epub 2019 Jun 18.

a Institute of Pharmaceutical Biology and Biotechnology , Heinrich Heine University , Universitaetsstrasse 1, Geb. 26.23 , Duesseldorf , Germany.

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http://dx.doi.org/10.1080/14786419.2019.1627348DOI Listing
June 2019

Indole Diterpenoids from an Endophytic Penicillium sp.

J Nat Prod 2019 06 22;82(6):1412-1423. Epub 2019 May 22.

Institute of Pharmaceutical Biology and Biotechnology , Heinrich Heine University Düsseldorf , Universitätsstrasse 1 , 40225 Düsseldorf , Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00723DOI Listing
June 2019

Indole alkaloids from the coprophilous fungus Aphanoascus fulvescens.

Fitoterapia 2019 Jul 7;136:104168. Epub 2019 May 7.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2019.05.007DOI Listing
July 2019

Spatial and temporal dynamics of bacterioplankton community composition in a subtropical dammed karst river of southwestern China.

Microbiologyopen 2019 09 6;8(9):e00849. Epub 2019 May 6.

Key Laboratory of Karst Dynamics, MLR & GZAR, Institute of Karst Geology, Chinese Academy of Geological Sciences, Guilin, China.

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http://dx.doi.org/10.1002/mbo3.849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741127PMC
September 2019

Sesquiterpenoids from the Endophytic Fungus Rhinocladiella similis.

J Nat Prod 2019 05 2;82(5):1055-1062. Epub 2019 May 2.

Institute of Pharmaceutical Biology and Biotechnology , Heinrich-Heine-Universität Düsseldorf , 40225 Düsseldorf , Germany.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00938DOI Listing
May 2019

Permeability analyses and three dimensional imaging of interferon gamma-induced barrier disintegration in intestinal organoids.

Stem Cell Res 2019 03 7;35:101383. Epub 2019 Feb 7.

Division of Molecular and Experimental Surgery, Department of Surgery, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Universitätsklinikum Erlangen, Translational Research Center, 91054 Erlangen, Germany; Optical Imaging Centre Erlangen (OICE), Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, 91052 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.scr.2019.101383DOI Listing
March 2019

New Acyclic Cytotoxic Jasplakinolide Derivative from the Marine Sponge .

Mar Drugs 2019 Feb 6;17(2). Epub 2019 Feb 6.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine University, Universitaetsstrasse 1, D-40225 Duesseldorf, Germany.

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http://dx.doi.org/10.3390/md17020100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409940PMC
February 2019

Cryptic Secondary Metabolites from the Sponge-Associated Fungus .

Mar Drugs 2019 Feb 3;17(2). Epub 2019 Feb 3.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.

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http://www.mdpi.com/1660-3397/17/2/99
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http://dx.doi.org/10.3390/md17020099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410417PMC
February 2019

In Situ Polyphosphate Nanoparticle Formation in Hybrid Poly(vinyl alcohol)/Karaya Gum Hydrogels: A Porous Scaffold Inducing Infiltration of Mesenchymal Stem Cells.

Adv Sci (Weinh) 2019 Jan 13;6(2):1801452. Epub 2018 Nov 13.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry University Medical Center of the Johannes Gutenberg University Duesbergweg 6 55128 Mainz Germany.

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http://dx.doi.org/10.1002/advs.201801452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343068PMC
January 2019

Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses.

Sci Rep 2019 01 17;9(1):193. Epub 2019 Jan 17.

Faculty of Biology, Medicine and Health, School of Biological Sciences, Manchester, M13 9PT, United Kingdom.

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http://www.nature.com/articles/s41598-018-36969-x
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http://dx.doi.org/10.1038/s41598-018-36969-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336827PMC
January 2019

Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis.

Cell Rep 2019 01;26(3):536-545.e4

Biomedical Sciences Research Centre (BSRC) "Alexander Fleming," Vari 16672, Greece; Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens 11527, Greece. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183201
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http://dx.doi.org/10.1016/j.celrep.2018.12.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334226PMC
January 2019

IL-10 signaling in dendritic cells is required for tolerance induction in a murine model of allergic airway inflammation.

Eur J Immunol 2019 02 3;49(2):302-312. Epub 2019 Jan 3.

Allergy Research Group, Department of Dermatology, Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/eji.201847883DOI Listing
February 2019

Biomimetic transformation of polyphosphate microparticles during restoration of damaged teeth.

Dent Mater 2019 02 3;35(2):244-256. Epub 2018 Dec 3.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.dental.2018.11.014DOI Listing
February 2019

Evaluating the IgMi mouse as a novel tool to study B-cell biology.

Eur J Immunol 2018 12 26;48(12):2068-2071. Epub 2018 Oct 26.

Lydia Becker Institute of Immunology and Inflammation, Faculty of Biology, Medicine and Health, Manchester Academic Health Science centre, The University of Manchester, Manchester, United Kingdom of Great Britain and Northern Ireland.

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http://doi.wiley.com/10.1002/eji.201847735
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http://dx.doi.org/10.1002/eji.201847735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750126PMC
December 2018

Induction of new metabolites from sponge-associated fungus Aspergillus carneus by OSMAC approach.

Fitoterapia 2018 Nov 10;131:9-14. Epub 2018 Oct 10.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0367326X183133
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http://dx.doi.org/10.1016/j.fitote.2018.10.008DOI Listing
November 2018

Role of ATP during the initiation of microvascularization: acceleration of an autocrine sensing mechanism facilitating chemotaxis by inorganic polyphosphate.

Biochem J 2018 10 31;475(20):3255-3273. Epub 2018 Oct 31.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany

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http://dx.doi.org/10.1042/BCJ20180535DOI Listing
October 2018

Influence of Altered Microbes on Soil Organic Carbon Availability in Karst Agricultural Soils Contaminated by Pb-Zn Tailings.

Front Microbiol 2018 31;9:2062. Epub 2018 Aug 31.

ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

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http://dx.doi.org/10.3389/fmicb.2018.02062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127319PMC
August 2018

A new depsidone derivative from mangrove sediment derived fungus .

Nat Prod Res 2019 Aug 20;33(15):2215-2222. Epub 2018 Aug 20.

a Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf , Düsseldorf , Germany.

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http://dx.doi.org/10.1080/14786419.2018.1496430DOI Listing
August 2019

Lanthanum-containing bioparticles are associated with the influence of lanthanum on high phosphate mediated bone marrow stromal cells viability.

Biometals 2018 10 19;31(5):771-784. Epub 2018 Jul 19.

ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany.

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http://dx.doi.org/10.1007/s10534-018-0121-7DOI Listing
October 2018

Transformation of Amorphous Polyphosphate Nanoparticles into Coacervate Complexes: An Approach for the Encapsulation of Mesenchymal Stem Cells.

Small 2018 07 30;14(27):e1801170. Epub 2018 May 30.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128, Mainz, Germany.

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http://doi.wiley.com/10.1002/smll.201801170
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http://dx.doi.org/10.1002/smll.201801170DOI Listing
July 2018

Tanzawaic acid derivatives from freshwater sediment-derived fungus Penicillium sp.

Fitoterapia 2018 Jul 17;128:258-264. Epub 2018 May 17.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Düsseldorf 40225, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2018.05.019DOI Listing
July 2018

Biophysical and photobiological basics of water-filtered infrared-A hyperthermia of superficial tumors.

Int J Hyperthermia 2018 10;35(1):26-36. Epub 2018 May 10.

d Department of Radiation Oncology , Lindenhofspital , Bern , Switzerland.

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https://www.tandfonline.com/doi/full/10.1080/02656736.2018.1
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http://dx.doi.org/10.1080/02656736.2018.1469169DOI Listing
August 2019

Amorphous polyphosphate, a smart bioinspired nano-/bio-material for bone and cartilage regeneration: towards a new paradigm in tissue engineering.

J Mater Chem B 2018 Apr 12;6(16):2385-2412. Epub 2018 Apr 12.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.1039/c8tb00241jDOI Listing
April 2018

Amorphous, Smart, and Bioinspired Polyphosphate Nano/Microparticles: A Biomaterial for Regeneration and Repair of Osteo-Articular Impairments In-Situ.

Int J Mol Sci 2018 Jan 31;19(2). Epub 2018 Jan 31.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.3390/ijms19020427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855649PMC
January 2018

Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri.

Z Naturforsch C J Biosci 2018 Apr;73(5-6):199-210

Institut für Pharmazeutische Biologie und Biotechnologie, Heinrich-Heine-Universität, Universitätsstrasse 1, Geb. 26.23, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1515/znc-2017-0161DOI Listing
April 2018

Uptake of polyphosphate microparticles in vitro (SaOS-2 and HUVEC cells) followed by an increase of the intracellular ATP pool size.

PLoS One 2017 29;12(12):e0188977. Epub 2017 Dec 29.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Duesbergweg 6, Mainz, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188977PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747424PMC
January 2018

New 2-Methoxy Acetylenic Acids and Pyrazole Alkaloids from the Marine Sponge Cinachyrella sp.

Mar Drugs 2017 Nov 11;15(11). Epub 2017 Nov 11.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich Heine University, Universitätsstraße 1, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.3390/md15110356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706045PMC
November 2017

Lactones from the Sponge-Derived Fungus Talaromyces rugulosus.

Mar Drugs 2017 Nov 14;15(11). Epub 2017 Nov 14.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.3390/md15110359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706048PMC
November 2017

Risk factors for hypocalcaemia after completion hemithyroidectomy in thyroid cancer.

Swiss Med Wkly 2017 27;147:w14513. Epub 2017 Oct 27.

Department of Otorhinolaryngology, Head and Neck Surgery, Kantonsspital Luzern, Switzerland.

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http://dx.doi.org/10.4414/smw.2017.14513DOI Listing
July 2018

Restoration of Impaired Metabolic Energy Balance (ATP Pool) and Tube Formation Potential of Endothelial Cells under "high glucose", Diabetic Conditions by the Bioinorganic Polymer Polyphosphate.

Polymers (Basel) 2017 Nov 4;9(11). Epub 2017 Nov 4.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.3390/polym9110575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418735PMC
November 2017

IL-6-Type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion.

Diabetes 2018 01 24;67(1):36-45. Epub 2017 Oct 24.

Division of Pediatric Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland

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http://dx.doi.org/10.2337/db17-0637DOI Listing
January 2018

Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein Fragment 25-35.

Int J Mol Sci 2017 Oct 16;18(10). Epub 2017 Oct 16.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.

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http://dx.doi.org/10.3390/ijms18102154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666835PMC
October 2017

Collagen-inducing biologization of prosthetic material for hernia repair: Polypropylene meshes coated with polyP/collagen.

J Biomed Mater Res B Appl Biomater 2018 08 10;106(6):2109-2121. Epub 2017 Oct 10.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, 55128, Mainz, Germany.

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http://doi.wiley.com/10.1002/jbm.b.34016
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http://dx.doi.org/10.1002/jbm.b.34016DOI Listing
August 2018

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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http://doi.wiley.com/10.1002/eji.201646632
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http://dx.doi.org/10.1002/eji.201646632DOI Listing
October 2017

3D printing of hybrid biomaterials for bone tissue engineering: Calcium-polyphosphate microparticles encapsulated by polycaprolactone.

Acta Biomater 2017 12 28;64:377-388. Epub 2017 Sep 28.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 6, 55128 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2017.09.031DOI Listing
December 2017

An evolutionary perspective on the role of mesencephalic astrocyte-derived neurotrophic factor (MANF): At the crossroads of poriferan innate immune and apoptotic pathways.

Biochem Biophys Rep 2017 Sep 18;11:161-173. Epub 2017 Mar 18.

Institute for Physiological Chemistry, University Medical Center, Johannes Gutenberg-University, Duesbergweg 6, D-55128 Mainz, Germany.

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http://dx.doi.org/10.1016/j.bbrep.2017.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614693PMC
September 2017

New amide and dioxopiperazine derivatives from leaves of Breynia nivosa.

Fitoterapia 2017 Oct 19;122:16-19. Epub 2017 Aug 19.

Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.fitote.2017.08.009DOI Listing
October 2017

Inorganic polyphosphate induces accelerated tube formation of HUVEC endothelial cells.

Cell Mol Life Sci 2018 01 2;75(1):21-32. Epub 2017 Aug 2.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Duesbergweg 6, 55128, Mainz, Germany.

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http://dx.doi.org/10.1007/s00018-017-2601-2DOI Listing
January 2018

Enhancement of Wound Healing in Normal and Diabetic Mice by Topical Application of Amorphous Polyphosphate. Superior Effect of a Host⁻Guest Composite Material Composed of Collagen (Host) and Polyphosphate (Guest).

Polymers (Basel) 2017 Jul 22;9(7). Epub 2017 Jul 22.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Mainz, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.3390/polym9070300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432407PMC
July 2017

Polyphosphate as a donor of high-energy phosphate for the synthesis of ADP and ATP.

J Cell Sci 2017 Aug 7;130(16):2747-2756. Epub 2017 Jul 7.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128 Mainz, Germany

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http://jcs.biologists.org/lookup/doi/10.1242/jcs.204941
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http://dx.doi.org/10.1242/jcs.204941DOI Listing
August 2017

Involvement of interleukin-1 type 1 receptors in lipopolysaccharide-induced sickness responses.

Brain Behav Immun 2017 Nov 24;66:165-176. Epub 2017 Jun 24.

Department of Clinical and Experimental Medicine, Linköping University, 581 85 Linköping, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2017.06.013DOI Listing
November 2017

The Understanding of the Metazoan Skeletal System, Based on the Initial Discoveries with Siliceous and Calcareous Sponges.

Mar Drugs 2017 Jun 12;15(6). Epub 2017 Jun 12.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.

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http://dx.doi.org/10.3390/md15060172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484122PMC
June 2017

[Hypothyreosis after Hemithyroidectomy - surprisingly frequent complication in aftercare].

Laryngorhinootologie 2018 01 8;97(1):24-29. Epub 2017 Jun 8.

Luzerner Kantonsspital, Klinik für Hals-Nasen-Ohren-Heilkunde.

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http://dx.doi.org/10.1055/s-0043-110856DOI Listing
January 2018

Fabrication of a new physiological macroporous hybrid biomaterial/bioscaffold material based on polyphosphate and collagen by freeze-extraction.

J Mater Chem B 2017 Jun 26;5(21):3823-3835. Epub 2017 Apr 26.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.

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http://dx.doi.org/10.1039/c7tb00306dDOI Listing
June 2017

Morphogenetically-Active Barrier Membrane for Guided Bone Regeneration, Based on Amorphous Polyphosphate.

Mar Drugs 2017 May 17;15(5). Epub 2017 May 17.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University Mainz, Duesbergweg 6, 55128 Mainz, Germany.

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http://dx.doi.org/10.3390/md15050142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450548PMC
May 2017

Bifunctional dentifrice: Amorphous polyphosphate a regeneratively active sealant with potent anti-Streptococcus mutans activity.

Dent Mater 2017 07 9;33(7):753-764. Epub 2017 May 9.

ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.dental.2017.04.009DOI Listing
July 2017

Contribution of aerobic anoxygenic phototrophic bacteria to total organic carbon pool in aquatic system of subtropical karst catchments, Southwest China: evidence from hydrochemical and microbiological study.

FEMS Microbiol Ecol 2017 06;93(6)

ERC Advanced Investigator Grant Research Group at Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, 55128 Mainz, Germany.

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http://dx.doi.org/10.1093/femsec/fix065DOI Listing
June 2017

Two-Armed Activation of Bone Mineral Deposition by the Flavones Baicalin and Baicalein, Encapsulated in Polyphosphate Microparticles.

Am J Chin Med 2017 2;45(3):533-555. Epub 2017 Apr 2.

* ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, D-55128 Mainz, Germany.

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http://dx.doi.org/10.1142/S0192415X1750032XDOI Listing
September 2017

A Novel Biomimetic Approach to Repair Enamel Cracks/Carious Damages and to Reseal Dentinal Tubules by Amorphous Polyphosphate.

Polymers (Basel) 2017 Mar 25;9(4). Epub 2017 Mar 25.

European Research Council-Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, D-55128 Mainz, Germany.

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http://dx.doi.org/10.3390/polym9040120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432492PMC
March 2017

Electrospinning of Bioactive Wound-Healing Nets.

Prog Mol Subcell Biol 2017 ;55:259-290

ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany.

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http://dx.doi.org/10.1007/978-3-319-51284-6_8DOI Listing
June 2017

Biocalcite and Carbonic Acid Activators.

Prog Mol Subcell Biol 2017 ;55:221-257

ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany.

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http://link.springer.com/10.1007/978-3-319-51284-6_7
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http://dx.doi.org/10.1007/978-3-319-51284-6_7DOI Listing
June 2017

New Target Sites for Treatment of Osteoporosis.

Prog Mol Subcell Biol 2017 ;55:187-219

ERC Advanced Investigator Group, Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, Duesbergweg 6, 55128, Mainz, Germany.

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http://dx.doi.org/10.1007/978-3-319-51284-6_6DOI Listing
June 2017