Werner Göbel

Werner Göbel

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Werner Göbel

Publications by authors named "Werner Göbel"

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From the beginning to the present state of molecular microbial pathogenesis-A tribute to Pascale Cossart.

Authors:
Werner Goebel

Mol Microbiol 2020 03;113(3):538-540

Max von Pettenkofer-Institut, Ludwig-Maximilians-Universität, München, Germany.

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http://dx.doi.org/10.1111/mmi.14450DOI Listing
March 2020

How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication.

Front Cell Infect Microbiol 2019 4;9:42. Epub 2019 Mar 4.

Max von Pettenkofer-Institute, Ludwig Maximilian University of Munich, Munich, Germany.

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http://dx.doi.org/10.3389/fcimb.2019.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409310PMC
November 2019

To Eat and to Be Eaten: Mutual Metabolic Adaptations of Immune Cells and Intracellular Bacterial Pathogens upon Infection.

Front Cell Infect Microbiol 2017 13;7:316. Epub 2017 Jul 13.

Max von Pettenkofer-Institute, Chair of Medical Microbiology and Hospital Epidemiology, Ludwig Maximilian University of MunichMünchen, Germany.

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http://dx.doi.org/10.3389/fcimb.2017.00316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508010PMC
March 2018

Metabolic adaptation of Chlamydia trachomatis to mammalian host cells.

Mol Microbiol 2017 03 31;103(6):1004-1019. Epub 2017 Jan 31.

Department of Microbiology, University of Würzburg, Biocenter, Am Hubland, Würzburg, D-97074, Germany.

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http://dx.doi.org/10.1111/mmi.13603DOI Listing
March 2017

Pathway analysis using (13) C-glycerol and other carbon tracers reveals a bipartite metabolism of Legionella pneumophila.

Mol Microbiol 2016 Apr 19;100(2):229-46. Epub 2016 Feb 19.

Max von Pettenkofer Institut, Ludwig-Maximilians Universität, Munich, Germany.

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http://dx.doi.org/10.1111/mmi.13313DOI Listing
April 2016

Listeria arpJ gene modifies T helper type 2 subset differentiation.

J Infect Dis 2015 Jul 13;212(2):223-33. Epub 2015 Jan 13.

Department of Immunology and Host Defenses, Ehime University Graduate School of Medicine, Toon, Japan.

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http://dx.doi.org/10.1093/infdis/jiv021DOI Listing
July 2015

Metabolic Adaptations of Intracellullar Bacterial Pathogens and their Mammalian Host Cells during Infection ("Pathometabolism").

Microbiol Spectr 2015 Jun;3(3)

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität München, Germany.

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http://dx.doi.org/10.1128/microbiolspec.MBP-0002-2014DOI Listing
June 2015

Metabolic host responses to infection by intracellular bacterial pathogens.

Front Cell Infect Microbiol 2013 9;3:24. Epub 2013 Jul 9.

Lehrstuhl für Biochemie, Center of Isotopologue Profiling, Technische Universität München Garching, Germany.

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http://dx.doi.org/10.3389/fcimb.2013.00024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705551PMC
December 2013

Metabolic adaptation of human pathogenic and related nonpathogenic bacteria to extra- and intracellular habitats.

FEMS Microbiol Rev 2012 Mar 14;36(2):435-62. Epub 2011 Sep 14.

Zentralinstitut für Ernährungs- und Lebensmittelforschung, Abteilung Mikrobiologie, Technische Universität München, Weihenstephan, Germany.

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https://academic.oup.com/femsre/article-lookup/doi/10.1111/j
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http://dx.doi.org/10.1111/j.1574-6976.2011.00301.xDOI Listing
March 2012

Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling.

BMC Genomics 2010 Oct 18;11:573. Epub 2010 Oct 18.

Zentralinstitut für Ernährungs- und Lebensmittelforschung (ZIEL), Abteilung Mikrobiologie, Technische Universität München, Weihenstephaner Berg 3, Freising, Germany.

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http://dx.doi.org/10.1186/1471-2164-11-573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091722PMC
October 2010

Mutations affecting export and activity of cytolysin A from Escherichia coli.

J Bacteriol 2010 Aug 28;192(15):4001-11. Epub 2010 May 28.

Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe-Universität, Paul-Ehrlich-Str 40, D-60596 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1128/JB.01283-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916382PMC
August 2010

Carbon metabolism of intracellular bacterial pathogens and possible links to virulence.

Nat Rev Microbiol 2010 Jun 10;8(6):401-12. Epub 2010 May 10.

Lehrstuhl für Biochemie, Technische Universität München, D-85747 Garching, Germany.

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http://dx.doi.org/10.1038/nrmicro2351DOI Listing
June 2010

The major PEP-phosphotransferase systems (PTSs) for glucose, mannose and cellobiose of Listeria monocytogenes, and their significance for extra- and intracellular growth.

Microbiology 2010 Apr 7;156(Pt 4):1069-1083. Epub 2010 Jan 7.

Lehrstuhl für Mikrobiologie, Biozentrum, Universität Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1099/mic.0.034934-0DOI Listing
April 2010

Glucose and glucose 6-phosphate as carbon sources in extra- and intracellular growth of enteroinvasive Escherichia coli and Salmonella enterica.

Microbiology 2010 Apr 14;156(Pt 4):1176-1187. Epub 2010 Jan 14.

Lehrstuhl für Mikrobiologie, Biozentrum der Universität Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1099/mic.0.034744-0DOI Listing
April 2010

The bacterial virulence factor InlC perturbs apical cell junctions and promotes cell-to-cell spread of Listeria.

Nat Cell Biol 2009 Oct 20;11(10):1212-8. Epub 2009 Sep 20.

Department of Molecular Genetics, University of Toronto. Toronto, Ontario, M5S 1A8, Canada.

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http://dx.doi.org/10.1038/ncb1964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755649PMC
October 2009

Improvement of the live vaccine strain Salmonella enterica serovar Typhi Ty21a for antigen delivery via the hemolysin secretion system of Escherichia coli.

Int J Med Microbiol 2009 Feb 15;299(2):109-19. Epub 2008 Aug 15.

Institut für Medizinische Strahlenkunde und Zellforschung, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2008.06.006DOI Listing
February 2009

ClyA cytolysin from Salmonella: distribution within the genus, regulation of expression by SlyA, and pore-forming characteristics.

Int J Med Microbiol 2009 Jan 19;299(1):21-35. Epub 2008 Aug 19.

Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2008.06.004DOI Listing
January 2009

Modulation of PrfA activity in Listeria monocytogenes upon growth in different culture media.

Microbiology 2008 Dec;154(Pt 12):3856-3876

Lehrstuhl für Mikrobiologie, Biozentrum, Universität Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1099/mic.0.2008/018283-0DOI Listing
December 2008

Glycerol metabolism and PrfA activity in Listeria monocytogenes.

J Bacteriol 2008 Aug 23;190(15):5412-30. Epub 2008 May 23.

Institut für Hygiene und Mikrobiologie, Universität Würzburg, Gebäude E1, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1128/JB.00259-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493282PMC
August 2008

Carbon metabolism of Listeria monocytogenes growing inside macrophages.

Mol Microbiol 2008 Aug 9;69(4):1008-17. Epub 2008 Jul 9.

Lehrstuhl für Biochemie, Technische Universität München, Lichtenbergstr 4, D-85747 Garching, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2008.06337.xDOI Listing
August 2008

Colonization of experimental murine breast tumours by Escherichia coli K-12 significantly alters the tumour microenvironment.

Cell Microbiol 2008 Jun 17;10(6):1235-48. Epub 2008 Jan 17.

Department of Microbiology, Biocenter, University of Wuerzburg, 97074 Wuerzburg, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2008.01122.xDOI Listing
June 2008

Prodrug converting enzyme gene delivery by L. monocytogenes.

BMC Cancer 2008 Apr 10;8:94. Epub 2008 Apr 10.

Biocenter (Microbiology), University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1186/1471-2407-8-94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2329648PMC
April 2008

Listeria monocytogenes as novel carrier system for the development of live vaccines.

Int J Med Microbiol 2008 Jan 23;298(1-2):45-58. Epub 2007 Oct 23.

Department of Microbiology, Biocenter, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2007.09.002DOI Listing
January 2008

Life of Listeria monocytogenes in the host cells' cytosol.

Microbes Infect 2007 Aug 7;9(10):1188-95. Epub 2007 May 7.

Theodor-Boveri-Institut (Biozentrum), Lehrstuhl für Mikrobiologie, Universität Würzburg, Josef-Schneider-Strasse 2, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.micinf.2007.05.006DOI Listing
August 2007

Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice.

Int J Med Microbiol 2007 Jun 19;297(3):151-62. Epub 2007 Apr 19.

Genelux Corporation, 3030 Bunker Hill St., Ste. 310, San Diego, CA 92109, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S143842210700019
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http://dx.doi.org/10.1016/j.ijmm.2007.01.008DOI Listing
June 2007

Species-specific differences in the activity of PrfA, the key regulator of listerial virulence genes.

J Bacteriol 2006 Nov 15;188(22):7941-56. Epub 2006 Sep 15.

Lehrstuhl für Mikrobiologie, Biozentrum, Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1128/JB.00473-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636310PMC
November 2006

Response regulator DegU of Listeria monocytogenes regulates the expression of flagella-specific genes.

FEMS Microbiol Lett 2005 Nov 22;252(2):287-98. Epub 2005 Sep 22.

Lehrstuhl für Mikrobiologie, Theodor Boveri-Institut für Biowissenschaften der Universität Würzburg, Germany.

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http://dx.doi.org/10.1016/j.femsle.2005.09.011DOI Listing
November 2005

A multidomain fusion protein in Listeria monocytogenes catalyzes the two primary activities for glutathione biosynthesis.

J Bacteriol 2005 Jun;187(11):3839-47

Tel Aviv University, The George S. Wise Faculty of Life Sciences, Department of Molecular Microbiology and Biotechnology, Ramat Aviv, 69978, Tel Aviv, Israel.

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http://jb.asm.org/cgi/doi/10.1128/JB.187.11.3839-3847.2005
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http://dx.doi.org/10.1128/JB.187.11.3839-3847.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112035PMC
June 2005

Bacterial delivery of functional messenger RNA to mammalian cells.

Cell Microbiol 2005 May;7(5):709-24

Lehrstuhl für Mikrobiologie, Biozentrum der Universität Würzburg, Am Hubland, Germany.

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http://dx.doi.org/10.1111/j.1462-5822.2005.00507.xDOI Listing
May 2005

Supportive and inhibitory elements of a putative PrfA-dependent promoter in Listeria monocytogenes.

Mol Microbiol 2005 Feb;55(4):986-97

Biocenter (Microbiology), University of Würzburg, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04417.xDOI Listing
February 2005

Evolutionary history of the genus Listeria and its virulence genes.

Syst Appl Microbiol 2005 Jan;28(1):1-18

Lehrstuhl für Mikrobiologie, Technische Universität München, Am Hochanger 4, D-85350 Freising, Germany.

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http://dx.doi.org/10.1016/j.syapm.2004.09.005DOI Listing
January 2005

Bacteria as DNA vaccine carriers for genetic immunization.

Int J Med Microbiol 2004 Oct;294(5):319-35

Department of Microbiology, Biocenter of the University, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2004.03.001DOI Listing
October 2004

Use of the alpha-hemolysin secretion system of Escherichia coli for antigen delivery in the Salmonella typhi Ty21a vaccine strain.

Int J Med Microbiol 2004 Oct;294(6):363-71

Institut für Medizinische Strahlenkunde und Zellforschung, University of Würzburg, Versbacher Str. 5, D-97078 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2004.07.010DOI Listing
October 2004

Molecular analysis of cytolysin A (ClyA) in pathogenic Escherichia coli strains.

J Bacteriol 2004 Aug;186(16):5311-20

Institut für Medizinische Mikrobiologie, Klinikum der Johann Wolfgang Goethe-Universität, 60596 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1128/JB.186.16.5311-5320.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC490944PMC
August 2004

New Listeria monocytogenes prfA* mutants, transcriptional properties of PrfA* proteins and structure-function of the virulence regulator PrfA.

Mol Microbiol 2004 Jun;52(6):1553-65

Grupo de Patogénesis Molecular Bacteriana, Unidad de Microbiología e Inmunología, Facultad de Veterinaria, Universidad Complutense de Madrid and Universidad de León, Spain.

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http://dx.doi.org/10.1111/j.1365-2958.2004.04052.xDOI Listing
June 2004

Bacterial infection of human hematopoietic stem cells induces monocytic differentiation.

FEMS Immunol Med Microbiol 2004 Mar;40(2):147-53

Department of Dermatology, University of Würzburg, Josef-Schneider-Str. 2, D-97080 Würzburg, Germany.

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http://dx.doi.org/10.1016/S0928-8244(03)00305-5DOI Listing
March 2004

Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins.

Nat Biotechnol 2004 Mar 8;22(3):313-20. Epub 2004 Feb 8.

Department of Biochemistry, School of Medicine, Loma Linda University, Loma Linda, California 92350, USA.

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http://dx.doi.org/10.1038/nbt937DOI Listing
March 2004

Inefficient replication of Listeria innocua in the cytosol of mammalian cells.

J Infect Dis 2004 Feb 27;189(3):393-401. Epub 2004 Jan 27.

Biocenter, Department of Microbiology, University of Wurzburg, Wurzburg, Germany.

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http://dx.doi.org/10.1086/381206DOI Listing
February 2004

Susceptibility of hematopoietic stem cells to pathogens: role in virus/bacteria tropism and pathogenesis.

FEMS Microbiol Lett 2003 Sep;226(2):203-7

Department of Dermatology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/S0378-1097(03)00643-8DOI Listing
September 2003

The role of human dendritic cells in meningococcal and listerial meningitis.

Int J Med Microbiol 2003 Aug;293(4):241-9

Dermatologische Universitätsklinik Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1078/1438-4221-00266DOI Listing
August 2003

Deletion of the gene encoding p60 in Listeria monocytogenes leads to abnormal cell division and loss of actin-based motility.

Infect Immun 2003 Jun;71(6):3473-84

Lehrstuhl für Mikrobiologie der Universität Würzburg, Theodor-Boveri-Institut für Biowissenschaften, Am Hubland, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155713PMC
http://dx.doi.org/10.1128/iai.71.6.3473-3484.2003DOI Listing
June 2003

The Leopoldina international symposium on parasitism, commensalism and symbiosis--common themes, different outcome.

Mol Microbiol 2003 Mar;47(6):1749-58

Lehrstuhl für Mikrobiologie, Theodor-Boveri-Institut, Biozentrum, Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1046/j.1365-2958.2003.03443.xDOI Listing
March 2003

Antibodies present in normal human serum inhibit invasion of human brain microvascular endothelial cells by Listeria monocytogenes.

Infect Immun 2003 Jan;71(1):95-100

Lehrstuhl für Mikrobiologie, Theodor-Boveri-Institut für Biowissenschaften der Universität Würzburg, Würzburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC143403PMC
http://dx.doi.org/10.1128/iai.71.1.95-100.2003DOI Listing
January 2003

Interaction of human hematopoietic stem cells with bacterial pathogens.

Blood 2002 Nov 18;100(10):3703-9. Epub 2002 Jul 18.

Department of Dermatology, and Institute for Microbiology, Theodor-Boveri-Institute, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1182/blood-2002-03-0898DOI Listing
November 2002

Differential regulation of multiple proteins of Escherichia coli and Salmonella enterica serovar Typhimurium by the transcriptional regulator SlyA.

J Bacteriol 2002 Jul;184(13):3549-59

Lehrstuhl für Mikrobiologie, Theodor-Boveri-Institut für Biowissenschaften (Biozentrum), Universität Würzburg, 97074 Würzburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC135123PMC
http://dx.doi.org/10.1128/jb.184.13.3549-3559.2002DOI Listing
July 2002

The E. coli alpha-hemolysin secretion system and its use in vaccine development.

Trends Microbiol 2002 Jan;10(1):39-45

Department of Microbiology, University of Würzburg, D-97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/s0966-842x(01)02259-4DOI Listing
January 2002

Hpt, a bacterial homolog of the microsomal glucose- 6-phosphate translocase, mediates rapid intracellular proliferation in Listeria.

Proc Natl Acad Sci U S A 2002 Jan 26;99(1):431-6. Epub 2001 Dec 26.

Grupo de Patogénesis Molecular Bacteriana, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain.

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http://dx.doi.org/10.1073/pnas.012363899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC117577PMC
January 2002