Publications by authors named "Wenxin Luo"

47 Publications

Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.

Cell Host Microbe 2021 Feb 3. Epub 2021 Feb 3.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, China; Research Unit of Frontier Technology of Structural Vaccinology, Chinese Academy of Medical Sciences, Xiamen, Fujian 361102, China. Electronic address:

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February 2021

Detection of SARS-CoV-2 and Its Mutated Variants via CRISPR-Cas13-Based Transcription Amplification.

Anal Chem 2021 02 29;93(7):3393-3402. Epub 2021 Jan 29.

Department of Respiratory and Critical Care Medicine, West China Medical School/West China Hospital, Sichuan University, Chengdu 610041, China.

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February 2021

Molecular characteristics of primary pulmonary lymphoepithelioma-like carcinoma based on integrated genomic analyses.

Signal Transduct Target Ther 2021 Jan 8;6(1). Epub 2021 Jan 8.

Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, No. 37, Guo Xue Alley, 610041, Chengdu, Sichuan, China.

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January 2021

[Preparation of anti-GPC3 single chain antibody for targeted detection of hepatocellular carcinoma].

Sheng Wu Gong Cheng Xue Bao 2020 Dec;36(12):2860-2867

State key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, School of Life Sciences, Xiamen University, Xiamen 361102, Fujian, China.

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December 2020

Comparison of Seven Commercial Severe Acute Respiratory Syndrome Coronavirus 2 Nucleic Acid Detection Reagents with Pseudovirus as Quality Control Material.

J Mol Diagn 2021 03 29;23(3):300-309. Epub 2020 Dec 29.

National Center for Clinical Laboratories, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China; Beijing Engineering Research Center of Laboratory Medicine, Beijing Hospital, Beijing, China; Graduate School, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. Electronic address:

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March 2021

Chronic exposure to microcystin-LR increases the risk of prostate cancer and induces malignant transformation of human prostate epithelial cells.

Chemosphere 2021 Jan 10;263:128295. Epub 2020 Sep 10.

Immunology and Reproduction Biology Laboratory, State Key Laboratory of Analytical Chemistry for Life Science, Medical School, Nanjing University, Nanjing, 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing University, Nanjing, 210093, China. Electronic address:

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January 2021

Risk factors for predicting mortality of COVID-19 patients: A systematic review and meta-analysis.

PLoS One 2020 30;15(11):e0243124. Epub 2020 Nov 30.

Department of Respiratory and Critical Care Medicine, West China Medical School/West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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December 2020

Radiomics: an overview in lung cancer management-a narrative review.

Ann Transl Med 2020 Sep;8(18):1191

Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.

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September 2020

COVID-19: Progress in diagnostics, therapy and vaccination.

Theranostics 2020 19;10(17):7821-7835. Epub 2020 Jun 19.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, 361102, China.

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August 2020

Structure guided maturation of a novel humanized anti-HBV antibody and its preclinical development.

Antiviral Res 2020 08 12;180:104757. Epub 2020 Mar 12.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, School of Life Science, Xiamen University; Xiamen, 361105, China.

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August 2020

The diagnostic efficiency of seven autoantibodies in lung cancer.

Eur J Cancer Prev 2020 07;29(4):315-320

Laboratory of Pathology, Key Laboratory of Transplantation Engineering and Immunology, Ministry of Health, West China Hospital, Sichuan University.

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July 2020

Identification and validation of novel circulating biomarkers for early diagnosis of lung cancer.

Lung Cancer 2019 09 18;135:130-137. Epub 2019 Jun 18.

Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China; Precision Medicine Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

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September 2019

[Advances in the application of claudins to tumor therapy].

Sheng Wu Gong Cheng Xue Bao 2019 Jun;35(6):931-941

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, School of Life Sciences, Xiamen University, Xiamen 361102, Fujian, China.

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June 2019

The Open Chromatin Landscape of Non-Small Cell Lung Carcinoma.

Cancer Res 2019 Oct 17;79(19):4840-4854. Epub 2019 Jun 17.

Department of Respiratory and Critical Care Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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October 2019

Vesicular Antibodies: A Bioactive Multifunctional Combination Platform for Targeted Therapeutic Delivery and Cancer Immunotherapy.

Adv Mater 2019 Apr 7;31(17):e1808294. Epub 2019 Mar 7.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics and National Institute of Diagnostics and Vaccine Development in Infectious Disease, School of Public Health, Xiamen University, Xiamen, 361102, China.

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April 2019

[Advance in research on recycling antibody].

Sheng Wu Gong Cheng Xue Bao 2019 Feb;35(2):183-194

School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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February 2019

An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency.

Theranostics 2019 1;9(1):210-231. Epub 2019 Jan 1.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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December 2019

In vitro and in vivo investigations of probiotic properties of lactic acid bacteria isolated from Chinese traditional sourdough.

Appl Microbiol Biotechnol 2019 Feb 4;103(4):1893-1903. Epub 2019 Jan 4.

College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China.

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February 2019

A bispecific broadly neutralizing antibody against enterovirus 71 and coxsackievirus A16 with therapeutic potential.

Antiviral Res 2019 01 9;161:28-35. Epub 2018 Nov 9.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen, 361102, PR China.

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January 2019

Epitope clustering analysis for vaccine-induced human antibodies in relationship to a panel of murine monoclonal antibodies against HPV16 viral capsid.

Vaccine 2018 10 1;36(45):6761-6771. Epub 2018 Oct 1.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, Fujian, PR China; School of Public Health, Xiamen University, Xiamen, Fujian, PR China. Electronic address:

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October 2018

Safety and tolerability of PD-1/PD-L1 inhibitors in the treatment of non-small cell lung cancer: a meta-analysis of randomized controlled trials.

J Cancer Res Clin Oncol 2018 Oct 17;144(10):1851-1859. Epub 2018 Jul 17.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, 37 Guoxue Xiang, Chengdu, 610041, China.

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October 2018

Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR.

Appl Microbiol Biotechnol 2018 Jul 8;102(14):5953-5964. Epub 2018 May 8.

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen, 361102, China.

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July 2018

Characteristics of genomic alterations of lung adenocarcinoma in young never-smokers.

Int J Cancer 2018 Oct 7;143(7):1696-1705. Epub 2018 May 7.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

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October 2018

Efficient development of a stable cell pool for antibody production using a single plasmid.

J Biochem 2018 May;163(5):391-398

National Institute of Diagnostics and Vaccine Development in Infectious Diseases, Xiamen University, Xiamen 361102, People's Republic of China.

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May 2018

Human cytomegalovirus vaccine development: Immune responses to look into vaccine strategy.

Hum Vaccin Immunother 2018 02 1;14(2):292-303. Epub 2017 Dec 1.

a State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, School of Life Science , Xiamen University , Xiamen , Fujian , China.

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February 2018

A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses.

Sci Transl Med 2017 Oct;9(412)

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, School of Public Health, Xiamen University, Xiamen 361102, Fujian, China.

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October 2017

Family-based whole exome sequencing of atopic dermatitis complicated with cataracts.

Oncotarget 2017 Aug 31;8(35):59446-59454. Epub 2017 Jul 31.

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, PR China.

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August 2017