Wenxin Li

Wenxin Li

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Wenxin Li

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Influence of Scanning on Nano Crystalline -Ti Alloys Fabricated by Selective Laser Melting and Their Applications in Biomedical Science.

J Nanosci Nanotechnol 2020 Mar;20(3):1605-1612

School of Digital Media and Design, Hangzhou Dianzi University, Hangzhou, 310018, China.

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http://dx.doi.org/10.1166/jnn.2020.17340DOI Listing
March 2020

DNA hypermethylation of aurora kinase A in hepatitis C virus‑positive hepatocellular carcinoma.

Mol Med Rep 2019 Sep 11;20(3):2519-2532. Epub 2019 Jul 11.

Department of Hepatopancreatobiliary Surgery, Cancer Hospital of China Medical University, Shenyang, Liaoning 110042, P.R. China.

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http://dx.doi.org/10.3892/mmr.2019.10487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691273PMC
September 2019

Hierarchically Porous W-Doped CoP Nanoflake Arrays as Highly Efficient and Stable Electrocatalyst for pH-Universal Hydrogen Evolution.

Small 2019 Sep 30;15(37):e1902613. Epub 2019 Jul 30.

School of Electronic Science and Engineering, and State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu, 610054, P. R. China.

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http://dx.doi.org/10.1002/smll.201902613DOI Listing
September 2019

3D hollow Co-Fe-P nanoframes immobilized on N,P-doped CNT as an efficient electrocatalyst for overall water splitting.

Nanoscale 2019 Sep 10. Epub 2019 Sep 10.

School of Electronic Science and Engineering, and State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu 610054, PR China.

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http://dx.doi.org/10.1039/c9nr05924eDOI Listing
September 2019

Thermostable potassium channel-inhibiting neurotoxins in processed scorpion medicinal material revealed by proteomic analysis: Implications of its pharmaceutical basis in traditional Chinese medicine.

J Proteomics 2019 Aug 4;206:103435. Epub 2019 Jul 4.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, China. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2019.103435DOI Listing
August 2019

Effects of physical parameters and chemical dispersant on the formation of oil-particle aggregates (OPAs) in marine environments.

Mar Pollut Bull 2019 Aug 5;148:66-74. Epub 2019 Aug 5.

College of Environmental Science and Engineering, Dalian Maritime University, Dalian 116026, China. Electronic address:

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http://dx.doi.org/10.1016/j.marpolbul.2019.07.069DOI Listing
August 2019

Study of release kinetics and degradation thermodynamics of ferric citrate liposomes.

Chem Phys Lipids 2019 Aug 23;225:104811. Epub 2019 Aug 23.

College of Chemistry and Material Science, Hebei Normal University, Shijiazhuang, 050024, China. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2019.104811DOI Listing
August 2019

Opportunities and challenges of co-targeting epidermal growth factor receptor and autophagy signaling in non-small cell lung cancer.

Oncol Lett 2019 Jul 20;18(1):499-506. Epub 2019 May 20.

Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, Zhejiang 310002, P.R. China.

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http://dx.doi.org/10.3892/ol.2019.10372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546992PMC
July 2019

One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages.

Mol Cell 2019 Jul 23. Epub 2019 Jul 23.

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; Department of Orthopedic Surgery of the Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.06.039DOI Listing
July 2019

Effect of deposition potential and concentration of electroactive substances on BiTe nanowires fabricated by electrochemical method.

Nanotechnology 2019 Jun 1;30(24):245702. Epub 2019 Mar 1.

University of Electronic Science and Technology of China, People's Republic of China. National Engineering Research Center of Radiation Control Materials, People's Republic of China. Key Laboratory of Multi-spectral Absorbing Materials and Structures of Ministry of Education, People's Republic of China.

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http://dx.doi.org/10.1088/1361-6528/ab0bdeDOI Listing
June 2019

Behavioral and electctrophysiological evidence for enhanced sensitivity to subtle variations of pain expressions of same-race than other-race faces.

Neuropsychologia 2019 Jun 18;129:302-309. Epub 2019 Apr 18.

School of Psychological and Cognitive Sciences, PKU-IDG/McGovern Institute for Brain Research, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuropsychologia.2019.04.008DOI Listing
June 2019

A Review on Catalytic Nanomaterials for Volatile Organic Compounds VOC Removal and Their Applications for Healthy Buildings.

Nanomaterials (Basel) 2019 Jun 23;9(6). Epub 2019 Jun 23.

Department of Building, School of Design and Environment, National University of Singapore, 4 Architecture Drive, Singapore 117566, Singapore.

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http://dx.doi.org/10.3390/nano9060910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631840PMC
June 2019

miR-1226-3p Promotes Sorafenib Sensitivity of Hepatocellular Carcinoma via Downregulation of DUSP4 Expression.

J Cancer 2019 2;10(12):2745-2753. Epub 2019 Jun 2.

Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.

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http://dx.doi.org/10.7150/jca.31804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584923PMC
June 2019

Interactions between oxytocin receptor gene and intergroup relationship on empathic neural responses to others' pain.

Soc Cogn Affect Neurosci 2019 May;14(5):505-517

School of Psychological and Cognitive Sciences, PKU-IDG/McGovern Institute for Brain Research, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.

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http://dx.doi.org/10.1093/scan/nsz029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545534PMC
May 2019

Diverse Structural Features of Potassium Channels Characterized by Scorpion Toxins as Molecular Probes.

Molecules 2019 May 29;24(11). Epub 2019 May 29.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://dx.doi.org/10.3390/molecules24112045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600638PMC
May 2019

Endostatin and Oxaliplatin-Based Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma: Results of a Phase II Study.

Oncologist 2019 Apr 8;24(4):461-e136. Epub 2019 Mar 8.

Department of Radiation Oncology, Hangzhou Cancer Hospital, Hangzhou, People's Republic of China

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http://dx.doi.org/10.1634/theoncologist.2019-0119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459259PMC
April 2019

Oxytocin modulates social value representations in the amygdala.

Nat Neurosci 2019 04 25;22(4):633-641. Epub 2019 Mar 25.

State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China.

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http://dx.doi.org/10.1038/s41593-019-0351-1DOI Listing
April 2019

WC nanodot-decorated CNT networks as a highly efficient and stable electrocatalyst for hydrogen evolution in acidic and alkaline media.

Nanoscale 2019 Mar;11(11):4876-4884

School of Electronic Science and Engineering, and State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu 610054, PR China.

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http://dx.doi.org/10.1039/c8nr10281cDOI Listing
March 2019

Defensins, a novel type of animal toxin-like potassium channel inhibitor.

Toxicon 2019 Jan 22;157:101-105. Epub 2018 Nov 22.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China; Biodrug Research Center, Wuhan University, Wuhan, 430072, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00410101183102
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http://dx.doi.org/10.1016/j.toxicon.2018.11.304DOI Listing
January 2019

The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response.

Virol Sin 2018 Dec 19;33(6):545-556. Epub 2018 Dec 19.

State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan, 430072, China.

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http://link.springer.com/10.1007/s12250-018-0068-4
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http://dx.doi.org/10.1007/s12250-018-0068-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335219PMC
December 2018

N-Acetylcysteine for Preventing of Acute Kidney Injury in Chronic Kidney Disease Patients Undergoing Cardiac Surgery: A Metaanalysis.

Heart Surg Forum 2018 12 19;21(6):E513-E521. Epub 2018 Dec 19.

Department of Respiratory Medicine, The First College of Clinical Medical Sciences, Yichang Central People's Hospital, China Three Gorges University, Yichang, Hubei province, China.

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http://journal.hsforum.com/index.php/HSF/article/view/2193
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http://dx.doi.org/10.1532/hsf.2193DOI Listing
December 2018

Histidine-rich Modification of a Scorpion-derived Peptide Improves Bioavailability and Inhibitory Activity against HSV-1.

Theranostics 2018 1;8(1):199-211. Epub 2018 Jan 1.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China.

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http://dx.doi.org/10.7150/thno.21425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743469PMC
November 2018

Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.

Immunity 2018 11 23;49(5):842-856.e7. Epub 2018 Oct 23.

Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, P.R. China; Program in Molecular and Cellular Biology, Zhejiang University School of Medicine, Hangzhou 310058, P.R. China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183038
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http://dx.doi.org/10.1016/j.immuni.2018.08.021DOI Listing
November 2018

Pharmacological characterization of human beta-defensins 3 and 4 on potassium channels: Evidence of diversity in beta-defensin-potassium channel interactions.

Peptides 2018 10 16;108:14-18. Epub 2018 Aug 16.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; Biodrug Research Center, Wuhan University, Wuhan 430072, China. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2018.08.005DOI Listing
October 2018

Long Non-Coding RNA PVT1/miR-150/ HIG2 Axis Regulates the Proliferation, Invasion and the Balance of Iron Metabolism of Hepatocellular Carcinoma.

Cell Physiol Biochem 2018 11;49(4):1403-1419. Epub 2018 Sep 11.

Department of Hepato-Billiary Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1159/000493445DOI Listing
October 2018

Triintsin, a human pathogenic fungus-derived defensin with broad-spectrum antimicrobial activity.

Peptides 2018 09 10;107:61-67. Epub 2018 Aug 10.

State Key Laboratory of Virology, Modern Virology Research Center, College of Life Sciences, Wuhan University, Wuhan 430072, China; Bio-drug Research Center, Wuhan University, Wuhan 430072, China. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2018.08.003DOI Listing
September 2018

Study on Formation Process and Models of Linear Fe Cluster Structure on a Si(111)-7 × 7-CH₃OH Surface.

Materials (Basel) 2018 Sep 3;11(9). Epub 2018 Sep 3.

The Institute for Solid State Physics, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8581, Japan.

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http://dx.doi.org/10.3390/ma11091593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163598PMC
September 2018

Low expression of VSIG4 is associated with poor prognosis in hepatocellular carcinoma patients with hepatitis B infection.

Cancer Manag Res 2018 20;10:3697-3705. Epub 2018 Sep 20.

Department of Hepatobiliary Surgery, Sun Yat- sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China,

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https://www.dovepress.com/low-expression-of-vsig4-is-associa
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http://dx.doi.org/10.2147/CMAR.S165822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159793PMC
September 2018

[Expression and identification of an antimicrobial peptide VIP in Pichia pastoris].

Sheng Wu Gong Cheng Xue Bao 2018 Jun;34(6):1002-1011

Lanzhou Lanshi Energy Equipment Engineering Institute CO., LTD, Lanzhou 730300, Gansu, China.

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http://dx.doi.org/10.13345/j.cjb.170506DOI Listing
June 2018

Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells.

Cell Death Dis 2018 05 22;9(6):585. Epub 2018 May 22.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310003, China.

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http://dx.doi.org/10.1038/s41419-018-0606-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964179PMC
May 2018

Polymerization of Isoprene Promoted by Aminophosphine(ory)-Fused Bipyridine Cobalt Complexes: Precise Control of Molecular Weight and cis-1,4- alt-3,4 Sequence.

Inorg Chem 2018 Apr 12;57(7):4088-4097. Epub 2018 Mar 12.

Faculty of Materials Science and Chemical Engineering , Ningbo University , Ningbo 315211 , P. R. China.

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http://dx.doi.org/10.1021/acs.inorgchem.8b00270DOI Listing
April 2018

Expression of recombinant α-toxin BmKM9 from scorpion Buthus martensii Karsch and its functional characterization on sodium channels.

Peptides 2018 01 3;99:153-160. Epub 2017 Oct 3.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; Biodrug Research Center, Wuhan University, Wuhan 430072, China. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2017.09.017DOI Listing
January 2018

Oxytocin effects on self-referential processing: behavioral and neuroimaging evidence.

Soc Cogn Affect Neurosci 2017 12;12(12):1845-1858

School of Psychological and Cognitive Sciences.

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http://dx.doi.org/10.1093/scan/nsx116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716198PMC
December 2017

Molecular characterization and expression analysis of CSαβ defensin genes from the scorpion .

Biosci Rep 2017 Dec 15;37(6). Epub 2017 Dec 15.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China

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http://dx.doi.org/10.1042/BSR20171282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435467PMC
December 2017

Treating autoimmune disorders with venom-derived peptides.

Expert Opin Biol Ther 2017 09 11;17(9):1065-1075. Epub 2017 Jul 11.

a State Key Laboratory of Virology, College of Life Science , Wuhan University , Wuhan , China.

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http://dx.doi.org/10.1080/14712598.2017.1346606DOI Listing
September 2017

Variant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma.

Oncotarget 2017 Jul;8(27):43990-44003

Department of Medical Microbiology, School of Medicine, Wuhan University, Wuhan 430071, P.R. China.

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http://dx.doi.org/10.18632/oncotarget.16702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546456PMC
July 2017

Induction of INKIT by Viral Infection Negatively Regulates Antiviral Responses through Inhibiting Phosphorylation of p65 and IRF3.

Cell Host Microbe 2017 Jul;22(1):86-98.e4

Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan 430072, China. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.06.013DOI Listing
July 2017

Discovery of three toxin peptides with Kv1.3 channel and IL-2 cytokine-inhibiting activities from Non-Buthidae scorpions, Chaerilus tricostatus and Chaerilus tryznai.

Peptides 2017 05 12;91:13-19. Epub 2017 Mar 12.

Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, College of Basic Medicine, Hubei University of Medicine, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2017.03.005DOI Listing
May 2017

Dual inhibiting OCT4 and AKT potently suppresses the propagation of human cancer cells.

Sci Rep 2017 04 6;7:46246. Epub 2017 Apr 6.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.

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http://dx.doi.org/10.1038/srep46246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382782PMC
April 2017

St20, a new venomous animal derived natural peptide with immunosuppressive and anti-inflammatory activities.

Toxicon 2017 Mar 8;127:37-43. Epub 2017 Jan 8.

Department of Emergency Medicine, Taihe Hospital, Hubei University of Medicine, Hubei, China; Institute of Basic Medical Sciences, College of Basic Medicine, Hubei University of Medicine, Hubei, China; Department of Clinical Laboratory, Dongfeng Hospital, Hubei University of Medicine, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2017.01.005DOI Listing
March 2017

Design, synthesis, and biological evaluation of novel 5-Alkyl-6-Adamantylmethylpyrimidin-4(3H)-ones as HIV-1 non-nucleoside reverse-transcriptase inhibitors.

Chem Biol Drug Des 2016 09 21;88(3):380-5. Epub 2016 Jun 21.

Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Ji'nan, Shandong, China.

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http://doi.wiley.com/10.1111/cbdd.12765
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http://dx.doi.org/10.1111/cbdd.12765DOI Listing
September 2016

Improving fascin inhibitors to block tumor cell migration and metastasis.

Mol Oncol 2016 08 1;10(7):966-80. Epub 2016 Apr 1.

Department of Physiology and Biophysics, Cornell University, Weill Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2016.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423182PMC
August 2016

Distinct oxytocin effects on belief updating in response to desirable and undesirable feedback.

Proc Natl Acad Sci U S A 2016 08 1;113(33):9256-61. Epub 2016 Aug 1.

School of Psychological and Cognitive Sciences, IDG/McGovern Institute for Brain Research, Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing 100080, China;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1604285113
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http://dx.doi.org/10.1073/pnas.1604285113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995949PMC
August 2016

K1K8: an Hp1404-derived antibacterial peptide.

Appl Microbiol Biotechnol 2016 Jun 8;100(11):5069-77. Epub 2016 Mar 8.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-016-7395-xDOI Listing
June 2016

Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket.

Eur J Med Chem 2016 Jun 3;115:53-62. Epub 2016 Mar 3.

Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44, West Culture Road, 250012, Jinan, Shandong, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.02.068DOI Listing
June 2016

Molecular basis for the toxin insensitivity of scorpion voltage-gated potassium channel MmKv1.

Biochem J 2016 05 7;473(9):1257-66. Epub 2016 Mar 7.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China Center for BioDrug Research, Wuhan University, Wuhan 430072, China

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http://dx.doi.org/10.1042/BCJ20160178DOI Listing
May 2016

Human beta-defensin 1, a new animal toxin-like blocker of potassium channel.

Toxicon 2016 Apr 5;113:1-6. Epub 2016 Feb 5.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; Center for BioDrug Research, Wuhan University, Wuhan 430072, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2016.02.007DOI Listing
April 2016

The Scorpion Toxin Analogue BmKTX-D33H as a Potential Kv1.3 Channel-Selective Immunomodulator for Autoimmune Diseases.

Toxins (Basel) 2016 Apr 19;8(4):115. Epub 2016 Apr 19.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://dx.doi.org/10.3390/toxins8040115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848641PMC
April 2016

A Scorpion Defensin BmKDfsin4 Inhibits Hepatitis B Virus Replication in Vitro.

Toxins (Basel) 2016 04 27;8(5). Epub 2016 Apr 27.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://dx.doi.org/10.3390/toxins8050124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885039PMC
April 2016

Scorpion Potassium Channel-blocking Defensin Highlights a Functional Link with Neurotoxin.

J Biol Chem 2016 Mar 27;291(13):7097-106. Epub 2016 Jan 27.

From the State Key Laboratory of Virology, College of Life Sciences and Center for BioDrug Research, Wuhan University, Wuhan 430072, China

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http://www.jbc.org/content/early/2016/01/27/jbc.M115.680611.
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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.680611
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http://dx.doi.org/10.1074/jbc.M115.680611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807291PMC
March 2016

Identification of two novel Chlorotoxin derivatives CA4 and CTX-23 with chemotherapeutic and anti-angiogenic potential.

Sci Rep 2016 Feb 2;6:19799. Epub 2016 Feb 2.

Translational Neurooncology Lab, Department of Neurosurgery, Universitätsklinikum Erlangen, Friedrich-Alexander University (FAU) of Erlangen - Nürnberg, D-91054 Erlangen, Germany.

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http://dx.doi.org/10.1038/srep19799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735682PMC
February 2016

The expression of astrocyte elevated gene-1 in human non-small-cell lung cancer and its relationship with postoperative chemotherapy and radiotherapy.

Histopathology 2015 Dec 17;67(6):817-26. Epub 2015 Jun 17.

Department of Radiation Oncology, The Third Affiliated Hospital of Harbin Medical University, Harbin, China.

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http://dx.doi.org/10.1111/his.12720DOI Listing
December 2015

Capture of Hyperthermal CO2 by Amorphous Water Ice via Molecular Embedding.

J Phys Chem A 2015 Dec 14;119(50):12238-44. Epub 2015 Aug 14.

The James Franck Institute and Department of Chemistry, The University of Chicago , 929 E. 57th Street, Chicago, Illinois 60637, United States.

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http://dx.doi.org/10.1021/acs.jpca.5b06287DOI Listing
December 2015

A new Kunitz-type plasmin inhibitor from scorpion venom.

Toxicon 2015 Nov 9;106:7-13. Epub 2015 Sep 9.

Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Hubei University of Medicine, Hubei, China; State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxicon.2015.09.004DOI Listing
November 2015

Human α-defensins are immune-related Kv1.3 channel inhibitors: new support for their roles in adaptive immunity.

FASEB J 2015 Oct 6;29(10):4324-33. Epub 2015 Jul 6.

*State Key Laboratory of Virology, College of Life Sciences, and Center for BioDrug Research, Wuhan University, Wuhan, China

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http://www.fasebj.org/doi/10.1096/fj.15-274787
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http://dx.doi.org/10.1096/fj.15-274787DOI Listing
October 2015

Engineering a peptide inhibitor towards the KCNQ1/KCNE1 potassium channel (IKs).

Peptides 2015 Sep 15;71:77-83. Epub 2015 Jul 15.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Hubei University of Medicine, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2015.07.002DOI Listing
September 2015

A single conserved basic residue in the potassium channel filter region controls KCNQ1 insensitivity toward scorpion toxins.

Biochem Biophys Rep 2015 Sep 21;3:62-67. Epub 2015 Jul 21.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei, China.

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http://dx.doi.org/10.1016/j.bbrep.2015.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668678PMC
September 2015

A p7 Ion Channel-derived Peptide Inhibits Hepatitis C Virus Infection in Vitro.

J Biol Chem 2015 Sep 6;290(38):23254-63. Epub 2015 Aug 6.

From the State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China

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http://dx.doi.org/10.1074/jbc.M115.662452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4645583PMC
September 2015

Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif.

Eur J Med Chem 2015 Sep 26;102:167-79. Epub 2015 Jul 26.

Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44, West Culture Road, 250012, Jinan, Shandong, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.07.043DOI Listing
September 2015

MicroRNA-720 promotes in vitro cell migration by targeting Rab35 expression in cervical cancer cells.

Cell Biosci 2015 25;5:56. Epub 2015 Sep 25.

College of Life Sciences and State Key Laboratory of Virology, Wuhan University, 430072 Wuhan, People's Republic of China.

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http://dx.doi.org/10.1186/s13578-015-0047-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583841PMC
September 2015

SjAPI-2 is the first member of a new neurotoxin family with Ascaris-type fold and KCNQ1 inhibitory activity.

Int J Biol Macromol 2015 Aug 23;79:504-10. Epub 2015 May 23.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2015.05.027DOI Listing
August 2015

Hp1404, a new antimicrobial peptide from the scorpion Heterometrus petersii.

PLoS One 2014 14;9(5):e97539. Epub 2014 May 14.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, PR China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097539PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020842PMC
June 2015

Genome-wide analysis of homeobox genes from Mesobuthus martensii reveals Hox gene duplication in scorpions.

Insect Biochem Mol Biol 2015 Jun 21;61:25-33. Epub 2015 Apr 21.

College of Life Sciences, Wuhan University, Wuhan, China. Electronic address:

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http://dx.doi.org/10.1016/j.ibmb.2015.04.002DOI Listing
June 2015

Kv Channel S1-S2 Linker Working as a Binding Site of Human β-Defensin 2 for Channel Activation Modulation.

J Biol Chem 2015 Jun 5;290(25):15487-95. Epub 2015 May 5.

From the State Key Laboratory of Virology, College of Life Sciences and the Center for BioDrug Research, Wuhan University, Wuhan 430072, China and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M115.639500
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http://dx.doi.org/10.1074/jbc.M115.639500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505463PMC
June 2015

Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells.

Nat Commun 2015 Jun 10;6:7209. Epub 2015 Jun 10.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China.

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http://dx.doi.org/10.1038/ncomms8209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490363PMC
June 2015

Cloning and Genomic Characterization of a Natural Insecticidal Peptide LaIT1 with Unique DDH Structural Fold.

J Biochem Mol Toxicol 2015 May 13;29(5):207-12. Epub 2015 Apr 13.

Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Hubei University of Medicine, Hubei, People's Republic of China; State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Hubei, People's Republic of China.

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http://dx.doi.org/10.1002/jbt.21686DOI Listing
May 2015

Toxin acidic residue evolutionary function-guided design of de novo peptide drugs for the immunotherapeutic target, the Kv1.3 channel.

Sci Rep 2015 May 8;5:9881. Epub 2015 May 8.

1] State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China [2] Center for BioDrug Research, Wuhan University, Wuhan 430072, China.

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http://www.nature.com/articles/srep09881
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http://dx.doi.org/10.1038/srep09881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424837PMC
May 2015

Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.

Cell Mol Life Sci 2015 Feb 19;72(4):821-32. Epub 2014 Aug 19.

College of Life Sciences, Wuhan University, Wuhan, 430072, Hubei, People's Republic of China.

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http://dx.doi.org/10.1007/s00018-014-1704-2DOI Listing
February 2015

Endogenous animal toxin-like human β-defensin 2 inhibits own K(+) channels through interaction with channel extracellular pore region.

Cell Mol Life Sci 2015 Feb 20;72(4):845-53. Epub 2014 Sep 20.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, 430072, China.

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http://dx.doi.org/10.1007/s00018-014-1715-zDOI Listing
February 2015

Nanodiamonds act as Trojan horse for intracellular delivery of metal ions to trigger cytotoxicity.

Part Fibre Toxicol 2015 Feb 5;12. Epub 2015 Feb 5.

Division of Physical Biology, and Bioimaging Center, Shanghai Synchrotron Radiation Facility, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai, 201800, China.

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http://dx.doi.org/10.1186/s12989-014-0075-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374301PMC
February 2015

Functional characterization of a new non-Kunitz serine protease inhibitor from the scorpion Lychas mucronatus.

Int J Biol Macromol 2015 Jan 21;72:158-62. Epub 2014 Aug 21.

Department of Biochemistry and Molecular Biology, Medicinal Macromolecular Laboratory, School of Basic Medical Sciences, Hubei University of Medicine, Hubei, China. Electronic address:

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http://dx.doi.org/10.1016/j.ijbiomac.2014.08.010DOI Listing
January 2015

Plectasin, first animal toxin-like fungal defensin blocking potassium channels through recognizing channel pore region.

Toxins (Basel) 2015 Jan 5;7(1):34-42. Epub 2015 Jan 5.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://www.mdpi.com/2072-6651/7/1/34
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http://dx.doi.org/10.3390/toxins7010034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303811PMC
January 2015

Functional characterization of two novel scorpion sodium channel toxins from Lychas mucronatus.

Toxicon 2014 Nov 4;90:318-25. Epub 2014 Sep 4.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China; Center for BioDrug Research, Wuhan University, Wuhan 430072, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00410101140030
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http://dx.doi.org/10.1016/j.toxicon.2014.08.075DOI Listing
November 2014

Molecular interactions with ice: molecular embedding, adsorption, detection, and release.

J Chem Phys 2014 Nov;141(18):18C514

The James Franck Institute and Department of Chemistry, The University of Chicago, 929 E. 57th Street, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1063/1.4895970DOI Listing
November 2014

γ-Tocotrienol protects against ovariectomy-induced bone loss via mevalonate pathway as HMG-CoA reductase inhibitor.

Bone 2014 Oct 11;67:200-7. Epub 2014 Jul 11.

Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282140025
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http://dx.doi.org/10.1016/j.bone.2014.07.006DOI Listing
October 2014

The effect of albumin fusion structure on the production and bioactivity of the somatostatin-28 fusion protein in Pichia pastoris.

J Ind Microbiol Biotechnol 2014 Jun 22;41(6):997-1006. Epub 2014 Apr 22.

Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi, 214063, Jiangsu, China,

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http://dx.doi.org/10.1007/s10295-014-1440-5DOI Listing
June 2014

Proteomic analysis of the venom from the scorpion Mesobuthus martensii.

J Proteomics 2014 Jun 26;106:162-80. Epub 2014 Apr 26.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.04.032DOI Listing
June 2014

Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues.

Biochem Biophys Res Commun 2014 Apr 3;447(1):70-6. Epub 2014 Apr 3.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China; Center for Biodrug Research, Wuhan University, Wuhan 430072, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.03.101DOI Listing
April 2014

BF9, the first functionally characterized snake toxin peptide with Kunitz-type protease and potassium channel inhibiting properties.

J Biochem Mol Toxicol 2014 Feb 14;28(2):76-83. Epub 2013 Nov 14.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China.

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http://dx.doi.org/10.1002/jbt.21538DOI Listing
February 2014

Inhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1.

Antiviral Res 2014 Feb 4;102:1-10. Epub 2013 Dec 4.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01663542130035
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http://dx.doi.org/10.1016/j.antiviral.2013.11.013DOI Listing
February 2014

Kv1.3 potassium channel-blocking toxin Ctri9577, novel gating modifier of Kv4.3 potassium channel from the scorpion toxin family.

Biochem Biophys Res Commun 2014 Feb 25;444(3):406-10. Epub 2014 Jan 25.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.01.094DOI Listing
February 2014

Overview of scorpion species from China and their toxins.

Toxins (Basel) 2014 Feb 26;6(3):796-815. Epub 2014 Feb 26.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://www.mdpi.com/2072-6651/6/3/796
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http://dx.doi.org/10.3390/toxins6030796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968362PMC
February 2014

Characterization of a novel BmαTX47 toxin modulating sodium channels: the crucial role of expression vectors in toxin pharmacological activity.

Toxins (Basel) 2014 Feb 26;6(3):816-29. Epub 2014 Feb 26.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan 430072, China.

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http://dx.doi.org/10.3390/toxins6030816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968363PMC
February 2014

Aberrant expression of ZNF268 alters the growth and migration of ovarian cancer cells.

Oncol Lett 2013 Jul 24;6(1):49-54. Epub 2013 Apr 24.

State Key Laboratory of Virology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072;

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http://dx.doi.org/10.3892/ol.2013.1318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742507PMC
July 2013