Wenge Zhu

Wenge Zhu

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Wenge Zhu

Wenge Zhu

Publications by authors named "Wenge Zhu"

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DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2).

Oncogene 2019 03 5;38(13):2364-2379. Epub 2018 Dec 5.

Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

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http://dx.doi.org/10.1038/s41388-018-0584-6DOI Listing
March 2019

The deubiquitylating enzyme USP15 regulates homologous recombination repair and cancer cell response to PARP inhibitors.

Nat Commun 2019 03 15;10(1):1224. Epub 2019 Mar 15.

State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing Proteome Research Center, Beijing Institute of Lifeomics, Beijing, 102206, China.

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http://dx.doi.org/10.1038/s41467-019-09232-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420636PMC
March 2019

miR-137 mediates the functional link between c-Myc and EZH2 that regulates cisplatin resistance in ovarian cancer.

Oncogene 2019 01 30;38(4):564-580. Epub 2018 Aug 30.

Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, 20037, USA.

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http://dx.doi.org/10.1038/s41388-018-0459-xDOI Listing
January 2019

Expression, Clinical Significance, and Functional Prediction of MNX1 in Breast Cancer.

Mol Ther Nucleic Acids 2018 Dec 27;13:399-406. Epub 2018 Sep 27.

Department of Breast Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China; Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S21622531183025
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http://dx.doi.org/10.1016/j.omtn.2018.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205149PMC
December 2018

Prognostic Values of LAPTM4B-35 in Human Cancer: A Meta-analysis.

J Cancer 2018 21;9(23):4355-4362. Epub 2018 Oct 21.

Department of Breast Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, Guangdong, China.

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http://dx.doi.org/10.7150/jca.26902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277661PMC
October 2018

The Impact of lncRNA Dysregulation on Clinicopathology and Survival of Breast Cancer: A Systematic Review and Meta-analysis.

Mol Ther Nucleic Acids 2018 Sep 3;12:359-369. Epub 2018 Jul 3.

Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, China. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037885PMC
September 2018

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.

Cancer Lett 2018 Aug 26;428:104-116. Epub 2018 Apr 26.

Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC, 20037, USA; GW Cancer Center, The George Washington University, Washington, DC, 20052, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03043835183029
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http://dx.doi.org/10.1016/j.canlet.2018.04.029DOI Listing
August 2018

Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells.

Transl Oncol 2018 Aug 5;11(4):1053-1064. Epub 2018 Jul 5.

Department of Gynecologic Oncology, Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2018.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034569PMC
August 2018

Association of two polymorphisms with breast cancer susceptibility in Chinese Han women.

Cancer Manag Res 2018 26;10:867-872. Epub 2018 Apr 26.

Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, People's Republic of China.

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http://dx.doi.org/10.2147/CMAR.S158433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927342PMC
April 2018

Genetic polymorphisms in caveolin-1 associate with breast cancer risk in Chinese Han population.

Oncotarget 2017 Oct 6;8(53):91654-91661. Epub 2017 Oct 6.

Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

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http://dx.doi.org/10.18632/oncotarget.21560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710954PMC
October 2017

Association of genetic polymorphisms in MIF with breast cancer risk in Chinese women.

Clin Exp Med 2017 Aug 14;17(3):395-401. Epub 2016 Nov 14.

Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.

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http://dx.doi.org/10.1007/s10238-016-0439-9DOI Listing
August 2017

And-1 is required for homologous recombination repair by regulating DNA end resection.

Nucleic Acids Res 2017 03;45(5):2531-2545

Department of Biochemistry and Molecular Medicine, The George Washington University School of Medicine and Health Science, 2300 Eye Street, N.W., Washington, DC 20037, USA.

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http://dx.doi.org/10.1093/nar/gkw1241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389477PMC
March 2017

Identification of genes that are essential to restrict genome duplication to once per cell division.

Oncotarget 2016 Jun;7(23):34956-76

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-2753, USA.

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http://dx.doi.org/10.18632/oncotarget.9008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085202PMC
June 2016

And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress.

EMBO J 2015 Aug 16;34(15):2096-110. Epub 2015 Jun 16.

Department of Biochemistry and Molecular Medicine, The George Washington University Medical School, Washington, DC, USA

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http://dx.doi.org/10.15252/embj.201488016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551354PMC
August 2015

TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis.

PLoS Genet 2015 Jul 1;11(7):e1005346. Epub 2015 Jul 1.

Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences & Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1371/journal.pgen.1005346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488437PMC
July 2015

Maintain Genomic Stability: Multitask of DNA Replication Proteins.

Authors:
Jing Hao Wenge Zhu

Transcr Open Access 2015 31;3(1). Epub 2015 Jan 31.

Department of Biochemistry and Molecular Medicine, The George Washington University Medical School, 2300 Eye Street N.W., Washington, DC 20037, USA.

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http://dx.doi.org/10.4172/2329-8936.1000e108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847296PMC
January 2015

Safety and efficacy studies on trivalent inactivated vaccines against infectious coryza.

Vet Immunol Immunopathol 2014 Mar 8;158(1-2):3-7. Epub 2013 Feb 8.

Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, EcoSciences Precinct, Dutton Park 4001, Brisbane, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.vetimm.2013.01.015DOI Listing
March 2014

Acidic nucleoplasmic DNA-binding protein (And-1) controls chromosome congression by regulating the assembly of centromere protein A (CENP-A) at centromeres.

J Biol Chem 2013 Jan 26;288(3):1480-8. Epub 2012 Nov 26.

Department of Biochemistry and Molecular Biology, The George Washington University Medical School, Washington, D. C. 20037, USA.

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http://dx.doi.org/10.1074/jbc.M112.429266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548461PMC
January 2013

The involvement of acidic nucleoplasmic DNA-binding protein (And-1) in the regulation of prereplicative complex (pre-RC) assembly in human cells.

J Biol Chem 2012 Dec 23;287(51):42469-79. Epub 2012 Oct 23.

Department of Biochemistry and Molecular Biology, The George Washington University Medical School, Washington, D. C. 20037, USA.

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http://dx.doi.org/10.1074/jbc.M112.404277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522249PMC
December 2012

The stability of histone acetyltransferase general control non-derepressible (Gcn) 5 is regulated by Cullin4-RING E3 ubiquitin ligase.

J Biol Chem 2011 Dec 10;286(48):41344-52. Epub 2011 Oct 10.

Department of Biochemistry and Molecular Biology, The George Washington University Medical School, Washington, DC 20037, USA.

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http://dx.doi.org/10.1074/jbc.M111.290767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308846PMC
December 2011

An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cells.

Mol Cancer Res 2011 Mar 21;9(3):294-310. Epub 2011 Jan 21.

National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892-2753, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-10-0570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060295PMC
March 2011

Selective killing of cancer cells by suppression of geminin activity.

Cancer Res 2009 Jun;69(11):4870-7

National Institute of Child Health and Human Development, NIH, Bethesda, Maryland 20892-2753, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749580PMC
June 2009

DNA replication and genomic instability.

Adv Exp Med Biol 2005 ;570:249-79

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1007/1-4020-3764-3_9DOI Listing
September 2008

Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication.

Genes Dev 2007 Sep 30;21(18):2288-99. Epub 2007 Aug 30.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1101/gad.1585607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1973143PMC
September 2007

Activation of fanconi anemia pathway in cells with re-replicated DNA.

Cell Cycle 2006 Oct 16;5(20):2306-9. Epub 2006 Oct 16.

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.4161/cc.5.20.3364DOI Listing
October 2006

An ATR- and BRCA1-mediated Fanconi anemia pathway is required for activating the G2/M checkpoint and DNA damage repair upon rereplication.

Mol Cell Biol 2006 Jun;26(12):4601-11

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Box 800733, Jordan Hall 1240, 1300 Jefferson Park Avenue, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1128/MCB.02141-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489121PMC
June 2006

PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination.

J Biol Chem 2006 Mar 9;281(10):6246-52. Epub 2006 Jan 9.

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1074/jbc.M512705200DOI Listing
March 2006

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint.

Mol Cell Biol 2004 Aug;24(16):7140-50

Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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http://mcb.asm.org/cgi/doi/10.1128/MCB.24.16.7140-7150.2004
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http://dx.doi.org/10.1128/MCB.24.16.7140-7150.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC479725PMC
August 2004

Evidence that the pre-mRNA splicing factor Clf1p plays a role in DNA replication in Saccharomyces cerevisiae.

Genetics 2002 Apr;160(4):1319-33

Department of Microbiology, University of Vermont, Burlington 05405-0068, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462043PMC
April 2002