Publications by authors named "Wendy Keung"

67Publications

Nonmulberry Silk Based Ink for Fabricating Mechanically Robust Cardiac Patches and Endothelialized Myocardium-on-a-Chip Application.

Adv Funct Mater 2020 Mar 20;30(12). Epub 2020 Jan 20.

Division of Engineering in Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Cambridge, MA 02139, USA.

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March 2020

Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation.

J Pharmacol Toxicol Methods 2019 Sep - Oct;99:106595. Epub 2019 Oct 17.

Ming-Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, Hong Kong; Novoheart, Vancouver, Canada.

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October 2019

Automated drug classification by machine learning analysis of drug screening data from human pluripotent stem cell-derived engineered cardiac tissue assays.

J Pharmacol Toxicol Methods 2019 Sep - Oct;99:106595. Epub 2019 Oct 17.

Novoheart, Vancouver, Canada; Ming-Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, Hong Kong; Dr. Li Dak-Sum Research Centre, The University of Hong Kong, Pokfulam, Hong Kong.

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October 2019

"Human heart-in-a-Jar": An electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells.

J Pharmacol Toxicol Methods 2019 Sep - Oct;99:106595. Epub 2019 Oct 17.

Novoheart, Vancouver, Canada; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.

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October 2019

Modeling the congenital heart condition of pulmonary atresia with intact ventricular septum using human induced pluripotent stem cells.

J Pharmacol Toxicol Methods 2019 Sep - Oct;99:106595. Epub 2019 Oct 17.

Dr. Li Dak-Sum Research Centre, The University of Hong Kong, Pokfulam, Hong Kong; Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong, Hong Kong.

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October 2019

Structural and Mechanistic Bases of Nuclear Calcium Signaling in Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes.

Stem Cells Int 2019 1;2019:8765752. Epub 2019 Apr 1.

Stem Cell & Regenerative Medicine Consortium, LKS Faculty of Medicine, University of Hong Kong, Hong Kong.

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April 2019

Probing flecainide block of I using human pluripotent stem cell-derived ventricular cardiomyocytes adapted to automated patch-clamping and 2D monolayers.

Toxicol Lett 2018 Sep 21;294:61-72. Epub 2018 May 21.

Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong; Dr. Li Dak-Sum Research Centre, The University of Hong Kong, Hong Kong; Ming Wai Lau Centre for Reparative Medicine, Karolinska Institutet, Hong Kong. Electronic address:

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September 2018

TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.

J Mol Cell Cardiol 2018 07 16;120:1-11. Epub 2018 May 16.

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China; Li Ka Shing Institute of Health Science, The Chinese University of Hong Kong, Hong Kong, China; Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, Hong Kong, China. Electronic address:

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July 2018

Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells.

Biomaterials 2018 05 10;163:116-127. Epub 2018 Feb 10.

Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Novoheart Limited, Shatin, Hong Kong. Electronic address:

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May 2018

Polycystin-2 Plays an Essential Role in Glucose Starvation-Induced Autophagy in Human Embryonic Stem Cell-Derived Cardiomyocytes.

Stem Cells 2018 04 3;36(4):501-513. Epub 2018 Jan 3.

School of Biomedical Sciences and Li Ka Shing Institute of Health Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong, People's Republic of China.

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April 2018