Publications


Megakaryocytes in Myeloproliferative Neoplasms Have Unique Somatic Mutations.
Am J Pathol 2017 Jul 11;187(7):1512-1522. Epub 2017 May 11.
School of Biomedical Sciences, University of Western Australia, Crawley, Western Australia, Australia; PathWest Laboratory Medicine, Nedlands, Western Australia, Australia. Electronic address:


Circumscribed sebaceous neoplasms: a morphological, immunohistochemical and molecular analysis.
Pathology 2016 Aug 14;48(5):454-62. Epub 2016 Jun 14.
Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, WA, Australia; Translational Cancer Pathology Laboratory, School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, WA, Australia.

Dysregulation of the intrinsic apoptotic pathway mediates megakaryocytic hyperplasia in myeloproliferative neoplasms.
J Clin Pathol 2016 Apr 8. Epub 2016 Apr 8.
School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia PathWest Laboratory Medicine, Nedlands, Western Australia, Australia.

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.
Sci Transl Med 2016 Mar 2;8(328):328ra30. Epub 2016 Mar 2.
Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK. National Health Service (NHS) Blood and Transplant, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK. National Institute for Health Research (NIHR) BioResource-Rare Diseases, Cambridge University Hospitals, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK. Human Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

Megakaryocytic hyperplasia in myeloproliferative neoplasms is driven by disordered proliferative, apoptotic and epigenetic mechanisms.
J Clin Pathol 2016 Feb 19;69(2):155-63. Epub 2015 Aug 19.
School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia PathWest Laboratory Medicine, Western Australia, Australia.

Mutational Analysis of BRAF Inhibitor-Associated Squamoproliferative Lesions.
J Mol Diagn 2015 Nov 28;17(6):644-51. Epub 2015 Aug 28.
Translational Cancer Pathology Laboratory, School of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia; Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, Western Australia, Australia. Electronic address:


Gray platelet syndrome: proinflammatory megakaryocytes and α-granule loss cause myelofibrosis and confer metastasis resistance in mice.
Blood 2014 Dec 25;124(24):3624-35. Epub 2014 Sep 25.
Department of Haematology, University of Cambridge, and National Health Service Blood and Transplant, Cambridge Biomedical Campus, Cambridge, United Kingdom;



Gain-of-function Lyn induces anemia: appropriate Lyn activity is essential for normal erythropoiesis and Epo receptor signaling.
Blood 2013 Jul 21;122(2):262-71. Epub 2013 May 21.
Cell Signalling Group, Laboratory for Cancer Medicine, Western Australian Institute for Medical Research and Centre for Medical Research, University of Western Australia, Perth, WA, Australia.




Can cytoplasmic nucleophosmin be detected by immunocytochemical staining of cell smears in acute myeloid leukemia?
Haematologica 2010 Apr 16;95(4):670-3. Epub 2009 Dec 16.
1Leukaemia Research Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.

Clinical utility of routine MPL exon 10 analysis in the diagnosis of essential thrombocythaemia and primary myelofibrosis.
Br J Haematol 2010 Apr 11;149(2):250-7. Epub 2010 Feb 11.
Department of Haematology, Haemato-Oncology Diagnostic Service, Addenbrooke's Hospital, Cambridge, UK.

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.
Nat Genet 2009 Nov 11;41(11):1182-90. Epub 2009 Oct 11.
Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK.




Bone marrow pathology in essential thrombocythemia: interobserver reliability and utility for identifying disease subtypes.
Blood 2008 Jan 20;111(1):60-70. Epub 2007 Sep 20.
Department of Cellular Pathology, Newcastle-upon-Tyne Hospitals National Health Service (NHS) Foundation Trust and Newcastle University, Newcastle-upon-Tyne, UK.




Conservation of unique cell-surface CD antigen mosaics in HIV-1-infected individuals.
Blood 2005 Aug 12;106(3):1003-7. Epub 2005 Apr 12.
University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Box 111, Cambridge CB2 2SP, United Kingdom.




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