Weizhen Wu

Weizhen Wu

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Weizhen Wu

Weizhen Wu

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MiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF.

Artif Cells Nanomed Biotechnol 2019 Dec;47(1):278-289

a Fujian Provincial Key Laboratory of Transplant Biology, Fuzhou Dongfang Hospital of Xiamen University (900 Hospital of the Joint Logistics Team), Fuzhou, Fujian, P.R. China.

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http://dx.doi.org/10.1080/21691401.2018.1553783DOI Listing
December 2019

lncRNA ATXN8OS promotes breast cancer by sequestering miR‑204.

Mol Med Rep 2019 Aug 6;20(2):1057-1064. Epub 2019 Jun 6.

Department of Urology, 900th Hospital of the Joint Logistics Support Force, People's Liberation Army, Fuzhou, Fujian 350000, P.R. China.

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http://dx.doi.org/10.3892/mmr.2019.10367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625414PMC
August 2019

Cell fate regulation by reticulon-4 in human prostate cancers.

J Cell Physiol 2019 Jul 27;234(7):10372-10385. Epub 2018 Nov 27.

Department of Urology, Fuzhou General Hospital, Fujian Medical University, Fuzhou, China.

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http://dx.doi.org/10.1002/jcp.27704DOI Listing
July 2019

Efficacy and Safety of Serenoa repens Extract Among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial.

Urology 2019 Jul 14;129:172-179. Epub 2019 Mar 14.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Hubei Institute of Urology, Wuhan, China. Electronic address:

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http://dx.doi.org/10.1016/j.urology.2019.02.030DOI Listing
July 2019

CYP3A4 and GCK genetic polymorphisms are the risk factors of tacrolimus-induced new-onset diabetes after transplantation in renal transplant recipients.

Eur J Clin Pharmacol 2018 Jun 15;74(6):723-729. Epub 2018 Mar 15.

Department of Urology, Fuzhou General Hospital of PLA, Fuzhou, Fujian, China.

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http://dx.doi.org/10.1007/s00228-018-2442-4DOI Listing
June 2018

Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells.

FEBS Open Bio 2018 May 10;8(5):743-750. Epub 2018 Apr 10.

Department of Urology Fuzhou General Hospital Fujian Medical University Fuzhou China.

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http://dx.doi.org/10.1002/2211-5463.12412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929937PMC
May 2018

Hydrogel-Based Fluorescent Dual pH and Oxygen Sensors Loaded in 96-Well Plates for High-Throughput Cell Metabolism Studies.

Sensors (Basel) 2018 Feb 13;18(2). Epub 2018 Feb 13.

Department of Materials Science and Engineering, Southern University of Science and Technology, No 1088 Xueyuan Road, Xili, Nanshan District, Shenzhen 518055, China.

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http://dx.doi.org/10.3390/s18020564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855129PMC
February 2018

Factor XIIa as a Novel Target for Thrombosis: Target Engagement Requirement and Efficacy in a Rabbit Model of Microembolic Signals.

J Pharmacol Exp Ther 2017 03 29;360(3):466-475. Epub 2016 Dec 29.

In Vitro Pharmacology (C.M.B., A.M.O., K.O., D.C.) and Cardiometabolic Diseases (X.W., W.W., X.Z., G.C., D.A.S., D.E.G., Z.C.), Merck & Co., Inc., Kenilworth, New Jersey

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http://dx.doi.org/10.1124/jpet.116.238493DOI Listing
March 2017

Inhibition of Factor XIa Reduces the Frequency of Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.

J Pharmacol Exp Ther 2017 03 29;360(3):476-483. Epub 2016 Dec 29.

Cardiometabolic Disease Biology (X.W., S.K., W.W., G.A.C., X.Z., P.A., D.S., M.E., D.E.G., Z.C.), Discovery Pharmaceutical Sciences (L.C.), In Vitro Pharmacology (K.E., D.C.), and Discovery Chemistry (S.E.), Merck Research Laboratories, Kenilworth, New Jersey; Lead Optimization Chemistry, Merck Research Laboratories, Rahway, New Jersey (A.A.).

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http://dx.doi.org/10.1124/jpet.116.238600DOI Listing
March 2017

Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer.

Med Oncol 2017 Feb 11;34(2):27. Epub 2017 Jan 11.

Department of Urology, Fuzhou General Hospital, Fujian Medical University, No.156, Xi'erhuan North Road, Fuzhou, 350025, China.

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http://dx.doi.org/10.1007/s12032-016-0870-5DOI Listing
February 2017

Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits.

J Pharmacol Exp Ther 2016 09 6;358(3):405-12. Epub 2016 Jul 6.

Cardiometabolic Disease Biology (X.Z., W.W., D.E.G., D.S., X.W.) and Discovery Pharmaceutical Sciences (L.C.), Merck Research Laboratories, Kenilworth, New Jersey

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http://dx.doi.org/10.1124/jpet.116.234575DOI Listing
September 2016

MYO6 knockdown inhibits the growth and induces the apoptosis of prostate cancer cells by decreasing the phosphorylation of ERK1/2 and PRAS40.

Oncol Rep 2016 Sep 29;36(3):1285-92. Epub 2016 Jun 29.

Department of Urology, Fuzhou Dongfang Hospital, Xiamen University, Xiamen 361005, P.R. China.

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http://dx.doi.org/10.3892/or.2016.4910DOI Listing
September 2016

Treatment of radiation-induced acute intestinal injury with bone marrow-derived mesenchymal stem cells.

Exp Ther Med 2016 Jun 11;11(6):2425-2431. Epub 2016 Apr 11.

Cell and Organ Transplant Institute, Fuzhou General Hospital, Fuzhou, Fujian 350025, P.R. China.

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https://www.spandidos-publications.com/10.3892/etm.2016.3248
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http://dx.doi.org/10.3892/etm.2016.3248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887770PMC
June 2016

Umbilical Cord Mesenchymal Stromal Cell With Autologous Bone Marrow Cell Transplantation in Established Type 1 Diabetes: A Pilot Randomized Controlled Open-Label Clinical Study to Assess Safety and Impact on Insulin Secretion.

Diabetes Care 2016 Jan 1;39(1):149-57. Epub 2015 Dec 1.

Organ Transplant Institute, Fuzhou General Hospital, Xiamen University, Fuzhou, China Diabetes Research Institute Federation, Hollywood, FL The Cure Alliance, Miami, FL

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http://dx.doi.org/10.2337/dc15-0171DOI Listing
January 2016

Relationships of related genetic polymorphisms and individualized medication of tacrolimus in patients with renal transplantation.

Int J Clin Exp Med 2015 15;8(10):19006-13. Epub 2015 Oct 15.

Department of Pharmacy, Fuzhou General Hospital of Nanjing Command PLA Fuzhou 350025, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694426PMC
January 2016

Factor XII full and partial null in rat confers robust antithrombotic efficacy with no bleeding.

Blood Coagul Fibrinolysis 2015 Dec;26(8):893-902

aIn Vivo Pharmacology bCardiometabolic Diseases cGenetically Engineered Models, Merck Sharp & Dohme Corp., Kenilworth, New Jersey dRNA Therapeutics; Merck Sharp & Dohme Corp., West Point, Pennsylvania, USA *Current affiliation: Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1097/MBC.0000000000000337DOI Listing
December 2015

Bone marrow mesenchymal stem cell implantation for the treatment of radioactivity‑induced acute skin damage in rats.

Mol Med Rep 2015 Nov 28;12(5):7065-71. Epub 2015 Aug 28.

Cell and Organ Transplant Institute, Fuzhou General Hospital, Fuzhou, Fujian 350025, P.R. China.

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http://dx.doi.org/10.3892/mmr.2015.4270DOI Listing
November 2015

Gliquidone versus metformin: differential effects on aorta in streptozotocin induced diabetic rats.

Chin Med J (Engl) 2014 ;127(7):1298-303

Department of Geriatrics, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China. Email:

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April 2015

Successful treatment of fibrosing cholestatic hepatitis following kidney transplantation with allogeneic hematopoietic stem cell transplantation: a case report.

Medicine (Baltimore) 2015 Feb;94(5):e480

From the Department of Hepatobiliary Disease, Fuzhou General Hospital (Dongfang Hospital), Xiamen University, Fuzhou 350025, China (DLL, JF, ZW); Department of Pathology, Fuzhou General Hospital (Dongfang Hospital), Xiamen University, Fuzhou 350025, China (ZZ); Department of Urology, Fuzhou General Hospital (Dongfang Hospital), Xiamen University, Fuzhou 350025, China (WW).

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http://dx.doi.org/10.1097/MD.0000000000000480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602713PMC
February 2015

Retrospective analysis of a large patient sample to determine p53 and Ki67 expressions in renal cell carcinoma.

J BUON 2014 Apr-Jun;19(2):512-6

Department of Urology, Fuzhou General Hospital, Fuzhou, 350025, Fujian, China.

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September 2014

Zucker Diabetic Fatty rats exhibit hypercoagulability and accelerated thrombus formation in the Arterio-Venous shunt model of thrombosis.

Thromb Res 2014 Aug 18;134(2):433-9. Epub 2014 Apr 18.

Department of Cardiometabolic Disease, Merck Research Laboratories, Kenilworth, New Jersey.

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http://dx.doi.org/10.1016/j.thromres.2014.04.008DOI Listing
August 2014

Protective effects of mesenchymal stromal cells on adriamycin-induced minimal change nephrotic syndrome in rats and possible mechanisms.

Cytotherapy 2014 Apr 10;16(4):471-84. Epub 2013 Oct 10.

Organ Transplant Institute, Fuzhou General Hospital, DongFang Hospital of Xiamen University and Fujian Key Laboratory of Transplant Biology, Fuzhou, Fujian 350025, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2013.08.002DOI Listing
April 2014

Autologous bone marrow mononuclear cell infusion and hyperbaric oxygen therapy in type 2 diabetes mellitus: an open-label, randomized controlled clinical trial.

Cytotherapy 2014 Feb 28;16(2):258-65. Epub 2013 Nov 28.

Organ Transplant Institute, Fuzhou General Hospital, Xiamen University, Fuzhou, Peoples Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2013.10.004DOI Listing
February 2014

Prevalence and management of post-transplant anemia in long-term follow-up of Chinese kidney transplant recipients: a single-center report.

Eur J Med Res 2013 Nov 15;18:45. Epub 2013 Nov 15.

Organ Transplant Institute, Fuzhou General Hospital, Xiamen University, 156 West Er'huan Road, Fuzhou 350025, China.

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http://eurjmedres.biomedcentral.com/articles/10.1186/2047-78
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http://dx.doi.org/10.1186/2047-783X-18-45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3835543PMC
November 2013

Insulin independence after islet transplantation through an indwelling catheter in the right gastric vein.

Int J Artif Organs 2013 Oct 20;36(9):620-3. Epub 2013 May 20.

Transplant Center, Fuzhou General Hospital, Xiamen University, Fuzhou - China.

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http://dx.doi.org/10.5301/ijao.5000183DOI Listing
October 2013

Electrosurgical enucleation versus bipolar transurethral resection for prostates larger than 70 ml: a prospective, randomized trial with 5-year followup.

J Urol 2013 Apr 31;189(4):1427-31. Epub 2012 Oct 31.

Department of Urology, Fuzhou General Hospital, Xiamen University, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.

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http://dx.doi.org/10.1016/j.juro.2012.10.117DOI Listing
April 2013

Differential profiles of thrombin inhibitors (heparin, hirudin, bivalirudin, and dabigatran) in the thrombin generation assay and thromboelastography in vitro.

Blood Coagul Fibrinolysis 2013 Apr;24(3):332-8

Thrombosis, Cardiovascular Diseases, Merck Research Laboratories, Rahway, NJ 07065, USA.

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http://dx.doi.org/10.1097/MBC.0b013e32835e4219DOI Listing
April 2013

Retroperitoneoscopic single-site renal pedicle lymphatic disconnection for the treatment of serious filarial chyluria.

Can J Urol 2013 Apr;20(2):6726-9

Department of Urology, Fuzhou General Hospital, Xiamen University, Fuzhou, China.

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April 2013

Post-transplant monitoring of soluble CD30 level as predictor of graft outcome: a single center experience from China.

Transpl Immunol 2012 Dec 16;27(4):146-50. Epub 2012 Oct 16.

Organ Transplant Institute, Fuzhou General Hospital, Fuzhou 350025, China.

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http://dx.doi.org/10.1016/j.trim.2012.10.002DOI Listing
December 2012

A new index for acute rejection after renal transplant: Notch receptor-1.

Exp Clin Transplant 2012 Oct 14;10(5):433-8. Epub 2012 May 14.

Organ Transplant Institute, Fuzhou General Hospital, No.156 Xi'erhuan North Road, Fuzhou, 350025, China.

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http://dx.doi.org/10.6002/ect.2011.0166DOI Listing
October 2012

Quantification of circulating D-dimer by peptide immunoaffinity enrichment and tandem mass spectrometry.

Anal Chem 2012 Aug 19;84(15):6891-8. Epub 2012 Jul 19.

Department of Molecular Biomarkers, Merck Research Laboratories, Rahway, New Jersey 07065, USA.

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http://dx.doi.org/10.1021/ac301494dDOI Listing
August 2012

Predicting renal graft failure by sCD30 levels and de novo HLA antibodies at 1year post-transplantation.

Transpl Immunol 2012 Jun 15;26(4):235-9. Epub 2012 Mar 15.

Organ Transplant Institute, Fuzhou General Hospital, Fuzhou 350025, China.

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http://dx.doi.org/10.1016/j.trim.2012.03.002DOI Listing
June 2012

Identification of genes affecting apolipoprotein B secretion following siRNA-mediated gene knockdown in primary human hepatocytes.

Atherosclerosis 2012 May 16;222(1):154-7. Epub 2012 Feb 16.

Cardiovascular Disease, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.02.012DOI Listing
May 2012

Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial.

JAMA 2012 Mar;307(11):1169-77

Organ Transplant Institute, Fuzhou General Hospital, Xiamen University and Fujian Key Laboratory of Transplant Biology, Fuzhou, China.

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http://dx.doi.org/10.1001/jama.2012.316DOI Listing
March 2012

High- vs low-power holmium laser lithotripsy: a prospective, randomized study in patients undergoing multitract minipercutaneous nephrolithotomy.

Urology 2012 Feb 15;79(2):293-7. Epub 2011 Oct 15.

Department of Urology, Fuzhou General Hospital, Xiamen University, Fuzhou, Fujian, China.

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http://dx.doi.org/10.1016/j.urology.2011.08.036DOI Listing
February 2012

Giant primary vaginal calculus secondary to vesicovaginal fistula with partial vaginal outlet obstruction in a 12-year-old girl.

Urology 2011 Oct 21;78(4):908-10. Epub 2011 Mar 21.

Department of Urology, Fuzhou General Hospital, Fuzhou, Fujian, China.

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http://dx.doi.org/10.1016/j.urology.2011.01.026DOI Listing
October 2011

Mesenchymal stem cells ameliorate ischemia-reperfusion-induced renal dysfunction by improving the antioxidant/oxidant balance in the ischemic kidney.

Urol Int 2011 28;86(2):191-6. Epub 2010 Sep 28.

Organ Transplant Institute, Fuzhou General Hospital, Xiamen University, Fuzhou, PR China.

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http://dx.doi.org/10.1159/000319366DOI Listing
July 2011

Phosphodiesterase 3 and 4 comprise the major cAMP metabolizing enzymes responsible for insulin secretion in INS-1 (832/13) cells and rat islets.

Biochem Pharmacol 2008 Oct 26;76(7):884-93. Epub 2008 Jul 26.

Department of Biochemistry and Molecular Biology, Merck Frosst Center for Therapeutic Research, Kirkland, Quebec, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520800507
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http://dx.doi.org/10.1016/j.bcp.2008.07.025DOI Listing
October 2008

Prediction of acute renal allograft rejection in early post-transplantation period by soluble CD30.

Transpl Immunol 2006 Jun 24;16(1):41-5. Epub 2006 Mar 24.

Department of Urology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1016/j.trim.2006.02.005DOI Listing
June 2006

Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator.

Mol Cell Biol 2005 Mar;25(6):2117-29

Laboratory of Biochemistry and Molecular Biology, The Rockefeller University, 1230 York Ave., #166, New York, NY 10021, USA.

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http://dx.doi.org/10.1128/MCB.25.6.2117-2129.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1061600PMC
March 2005

Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors.

Mol Cell Biol 2004 Sep;24(18):8244-54

Laboratory of Biochemistry and Molecular Biology, Rockefeller University, 1230 York Ave., New York, NY 10021, USA.

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http://dx.doi.org/10.1128/MCB.24.18.8244-8254.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC515042PMC
September 2004