Weiyun Shi

Weiyun Shi

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Nicotinamide inhibits corneal endothelial mesenchymal transition and accelerates wound healing.

Exp Eye Res 2019 Jul 24;184:227-233. Epub 2019 Apr 24.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong First Medical University & Shandong Academy of Medical Sciences, China. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2019.04.012DOI Listing
July 2019

Blood Vessels and Lymphatic Vessels in the Cornea and Iris After Penetrating Keratoplasty.

Cornea 2019 Jun;38(6):742-747

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.1097/ICO.0000000000001922DOI Listing
June 2019

TIPE2 suppresses Pseudomonas aeruginosa keratitis by inhibiting NF-κB signaling and the infiltration of inflammatory cells.

J Infect Dis 2019 May 8. Epub 2019 May 8.

Medical College, Qingdao University, Qingdao, China.

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http://dx.doi.org/10.1093/infdis/jiz246DOI Listing
May 2019

Different Effects of Pro-Inflammatory Factors and Hyperosmotic Stress on Corneal Epithelial Stem/Progenitor Cells and Wound Healing in Mice.

Stem Cells Transl Med 2019 Jan 9;8(1):46-57. Epub 2018 Oct 9.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, People's Republic of China.

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http://dx.doi.org/10.1002/sctm.18-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312447PMC
January 2019

MicroRNA-mediated regulation of T helper type 17/regulatory T-cell balance in autoimmune disease.

Immunology 2018 12 10;155(4):427-434. Epub 2018 Sep 10.

Centre for Antibody Drug, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

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http://doi.wiley.com/10.1111/imm.12994
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http://dx.doi.org/10.1111/imm.12994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231006PMC
December 2018

Autocrine IL-1β mediates the promotion of corneal neovascularization by senescent fibroblasts.

Am J Physiol Cell Physiol 2018 11 29;315(5):C734-C743. Epub 2018 Aug 29.

Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences , Qingdao, Shandong , China.

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https://www.physiology.org/doi/10.1152/ajpcell.00205.2017
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http://dx.doi.org/10.1152/ajpcell.00205.2017DOI Listing
November 2018

The poisoning effect of PbO and PbCl on CeO-TiO catalyst for selective catalytic reduction of NO with NH.

J Colloid Interface Sci 2018 Oct 22;528:82-91. Epub 2018 May 22.

College of Pipeline and Civil Engineering, China University of Petroleum, 66 Changjiang West Road, Qingdao 266580, China.

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http://dx.doi.org/10.1016/j.jcis.2018.05.061DOI Listing
October 2018

Rapamycin Nano-Micelle Ophthalmic Solution Reduces Corneal Allograft Rejection by Potentiating Myeloid-Derived Suppressor Cells' Function.

Front Immunol 2018 8;9:2283. Epub 2018 Oct 8.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.3389/fimmu.2018.02283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186809PMC
October 2018

Characteristics of New Onset Herpes Simplex Keratitis after Keratoplasty.

J Ophthalmol 2018 22;2018:4351460. Epub 2018 Oct 22.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China.

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https://www.hindawi.com/journals/joph/2018/4351460/
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http://dx.doi.org/10.1155/2018/4351460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217905PMC
October 2018

miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A.

J Immunol 2018 09 16;201(5):1412-1420. Epub 2018 Jul 16.

Center for Antibody Drug, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China 518055;

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http://dx.doi.org/10.4049/jimmunol.1800189DOI Listing
September 2018

Cyclosporine a drug-delivery system for high-risk penetrating keratoplasty: Stabilizing the intraocular immune microenvironment.

PLoS One 2018 7;13(5):e0196571. Epub 2018 May 7.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196571PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937766PMC
August 2018

Mini-Sheet Injection for Cultured Corneal Endothelial Transplantation.

Tissue Eng Part C Methods 2018 08;24(8):474-479

2 Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute , Shandong Academy of Medical Sciences, Qingdao, China .

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https://www.liebertpub.com/doi/10.1089/ten.tec.2018.0077
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http://dx.doi.org/10.1089/ten.TEC.2018.0077DOI Listing
August 2018

Cancer Lipid Metabolism Confers Antiangiogenic Drug Resistance.

Cell Metab 2018 Jul 31;28(1):104-117.e5. Epub 2018 May 31.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm 171 77, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.05.005DOI Listing
July 2018

Outcomes of Wound Dehiscence after Penetrating Keratoplasty and Lamellar Keratoplasty.

J Ophthalmol 2018 8;2018:1435389. Epub 2018 Jul 8.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan 250021, China.

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http://dx.doi.org/10.1155/2018/1435389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079506PMC
July 2018

Role of Dendritic Cells and Inflammatory Cells in Herpetic Endotheliitis: Analysis Using In Vivo Confocal Microscopy.

Cornea 2018 Jun;37(6):748-754

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China.

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http://dx.doi.org/10.1097/ICO.0000000000001571DOI Listing
June 2018

Inflammatory cytokine TNF-α promotes corneal endothelium apoptosis via upregulating TIPE2 transcription during corneal graft rejection.

Graefes Arch Clin Exp Ophthalmol 2018 Apr 26;256(4):709-715. Epub 2018 Feb 26.

Medical College, Qingdao University, 38 Dengzhou Road, Qingdao, 266021, China.

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http://dx.doi.org/10.1007/s00417-018-3913-0DOI Listing
April 2018

Epithelium-derived miR-204 inhibits corneal neovascularization.

Exp Eye Res 2018 02 12;167:122-127. Epub 2017 Dec 12.

Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, Shandong, China. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2017.12.001DOI Listing
February 2018

Early vitrectomy for dense vitreous hemorrhage in adults with non-traumatic and non-diabetic retinopathy.

J Int Med Res 2017 Dec 19;45(6):2065-2071. Epub 2017 Jun 19.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China.

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http://dx.doi.org/10.1177/0300060517708942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805203PMC
December 2017

MicroRNA‑494 inhibits nerve growth factor‑induced cell proliferation by targeting cyclin D1 in human corneal epithelial cells.

Mol Med Rep 2017 Oct 25;16(4):4133-4142. Epub 2017 Jul 25.

Department of Ophthalmology and Visual Science, Shanghai Eye, Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Shanghai 200031, P.R. China.

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http://dx.doi.org/10.3892/mmr.2017.7083DOI Listing
October 2017

MicroRNA-122 ameliorates corneal allograft rejection through the downregulation of its target CPEB1.

Cell Death Discov 2017 15;3:17021. Epub 2017 May 15.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, People's Republic of China.

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http://dx.doi.org/10.1038/cddiscovery.2017.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431487PMC
May 2017

Notch signaling modulates proliferative vitreoretinopathy via regulating retinal pigment epithelial-to-mesenchymal transition.

Histochem Cell Biol 2017 Mar 7;147(3):367-375. Epub 2016 Sep 7.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372 Jingsi Road, Jinan, 250021, China.

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http://dx.doi.org/10.1007/s00418-016-1484-xDOI Listing
March 2017

Upregulation of NLRP3 inflammasome components in Mooren's ulcer.

Graefes Arch Clin Exp Ophthalmol 2017 Mar 28;255(3):607-612. Epub 2016 Oct 28.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, 5 Yanerdao Road, Qingdao, 266071, China.

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http://dx.doi.org/10.1007/s00417-016-3516-6DOI Listing
March 2017

Subconjunctival Bevacizumab Injection Impairs Corneal Innervations and Epithelial Wound Healing in Mice.

Invest Ophthalmol Vis Sci 2017 03;58(3):1469-1477

Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.16-20926DOI Listing
March 2017

VEGF-B promotes recovery of corneal innervations and trophic functions in diabetic mice.

Sci Rep 2017 01 16;7:40582. Epub 2017 Jan 16.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.1038/srep40582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238415PMC
January 2017

c-Rel is Required for the Induction of pTregs in the Eye but Not in the Gut Mucosa.

Immunol Invest 2016 Nov 25;45(8):776-786. Epub 2016 May 25.

b Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences , Shenzhen , People's Republic of China.

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http://dx.doi.org/10.3109/08820139.2016.1172639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154251PMC
November 2016

Precisely Controlled Side Cut in Femtosecond Laser-Assisted Deep Lamellar Keratoplasty for Advanced Keratoconus.

Cornea 2016 Oct;35(10):1289-94

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China.

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http://dx.doi.org/10.1097/ICO.0000000000000962DOI Listing
October 2016

Active Pedicle Epithelial Flap Transposition Combined with Amniotic Membrane Transplantation for Treatment of Nonhealing Corneal Ulcers.

J Ophthalmol 2016 17;2016:5742346. Epub 2016 Oct 17.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372 Jingsi Road, Jinan 250021, China.

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http://dx.doi.org/10.1155/2016/5742346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086501PMC
October 2016

Therapeutic dilemma in fungal keratitis: administration of steroids for immune rejection early after keratoplasty.

Graefes Arch Clin Exp Ophthalmol 2016 Aug 24;254(8):1585-1589. Epub 2016 Jun 24.

From Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://link.springer.com/10.1007/s00417-016-3412-0
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http://dx.doi.org/10.1007/s00417-016-3412-0DOI Listing
August 2016

Immunological Properties of Corneal Epithelial-Like Cells Derived from Human Embryonic Stem Cells.

PLoS One 2016 15;11(3):e0150731. Epub 2016 Mar 15.

Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, Shandong, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0150731PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792422PMC
July 2016

Conjunctival flap covering combined with antiviral and steroid therapy for severe herpes simplex virus necrotizing stromal keratitis.

ScientificWorldJournal 2015 15;2015:565964. Epub 2015 Feb 15.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372 Jingsi Road, Jinan 250021, China.

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http://downloads.hindawi.com/journals/tswj/2015/565964.pdf
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http://www.hindawi.com/journals/tswj/2015/565964/
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http://dx.doi.org/10.1155/2015/565964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345056PMC
April 2016

Limitations of Keratoplasty in China: A Survey Analysis.

PLoS One 2015 10;10(7):e0132268. Epub 2015 Jul 10.

Department of Ophthalmology and Visual Science, Eye, and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132268PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498799PMC
April 2016

Notch signaling regulates M2 type macrophage polarization during the development of proliferative vitreoretinopathy.

Cell Immunol 2015 Nov-Dec;298(1-2):77-82. Epub 2015 Sep 16.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China; State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2015.09.005DOI Listing
April 2016

Total ocular surface amniotic membrane transplantation for paraquat-induced ocular surface injury.

Can J Ophthalmol 2015 Dec;50(6):461-5

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China. Electronic address:

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http://dx.doi.org/10.1016/j.jcjo.2015.08.002DOI Listing
December 2015

The Unevenness and Non-orthogonal State of Distribution of Corneal Thickness and the Influence on Correction of Myopic Astigmatism by LASEK.

Cell Biochem Biophys 2015 Sep;73(1):35-40

Department of Ophthalmology, Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372#, Jingsi Road, Jinan, Shandong, China.

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http://link.springer.com/10.1007/s12013-015-0571-2
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http://dx.doi.org/10.1007/s12013-015-0571-2DOI Listing
September 2015

Xenogeneic acellular conjunctiva matrix as a scaffold of tissue-engineered corneal epithelium.

PLoS One 2014 6;9(11):e111846. Epub 2014 Nov 6.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, Shandong, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111846PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222936PMC
July 2015

Modified lamellar keratoplasty and immunosuppressive therapy guided by in vivo confocal microscopy for perforated Mooren's ulcer.

Br J Ophthalmol 2015 Jun 6;99(6):778-83. Epub 2015 Jan 6.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.1136/bjophthalmol-2014-306012DOI Listing
June 2015

Effects of Lamellar Keratectomy and Intrastromal Injection of 0.2% Fluconazole on Fungal Keratitis.

J Ophthalmol 2015 7;2015:656027. Epub 2015 May 7.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan 250021, China.

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http://dx.doi.org/10.1155/2015/656027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439489PMC
June 2015

[The status quo and expectation of corneal research in China].

Zhonghua Yan Ke Za Zhi 2014 Sep;50(9):641-5

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September 2014

Modified tectonic keratoplasty with minimal corneal graft for corneal perforation in severe Stevens--Johnson syndrome: a case series study.

BMC Ophthalmol 2014 Aug 8;14:97. Epub 2014 Aug 8.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372 Jingsi Road, Jinan 250021, P,R, China.

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http://dx.doi.org/10.1186/1471-2415-14-97DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129433PMC
August 2014

Big bubble deep anterior lamellar keratoplasty for management of deep fungal keratitis.

J Ophthalmol 2014 1;2014:209759. Epub 2014 Jul 1.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 372 Jingsi Road, Jinan 250021, China ; Shandong Eye Institute, 5 Yanerdao Road, Qingdao 266071, China.

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http://dx.doi.org/10.1155/2014/209759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106058PMC
August 2014

Lamellar keratoplasty following thermokeratoplasty in the treatment of acute corneal hydrops.

Am J Ophthalmol 2014 Jul 31;158(1):26-31.e1. Epub 2014 Mar 31.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China. Electronic address:

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http://dx.doi.org/10.1016/j.ajo.2014.03.011DOI Listing
July 2014

Combined anterior chamber washout, amniotic membrane transplantation, and topical use of corticosteroids for severe peripheral ulcerative keratitis.

Cornea 2014 Jun;33(6):559-64

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Jinan, China.

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http://dx.doi.org/10.1097/ICO.0000000000000130DOI Listing
June 2014

Partial lamellar keratoplasty for peripheral corneal disease using a graft from the glycerin-preserved corneoscleral rim.

Graefes Arch Clin Exp Ophthalmol 2014 Jun 6;252(6):963-8. Epub 2014 May 6.

Shandong Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, 5 Yanerdao Road, Qingdao, 266071, People's Republic of China.

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http://dx.doi.org/10.1007/s00417-014-2642-2DOI Listing
June 2014

Transplantation of tissue-engineered human corneal endothelium in cat models.

Mol Vis 2013 18;19:400-7. Epub 2013 Feb 18.

Key Laboratory for Corneal Tissue Engineering, Ocean University of China, Qingdao, Shandong Province, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580986PMC
September 2013

Author reply: To PMID 23246118.

Ophthalmology 2013 Sep;120(9):e65

Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2013.05.020DOI Listing
September 2013

Author reply: To PMID 23246118.

Ophthalmology 2013 Sep;120(9):e66

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http://dx.doi.org/10.1016/j.ophtha.2013.06.008DOI Listing
September 2013

A novel cyclosporine a drug-delivery system for prevention of human corneal rejection after high-risk keratoplasty: a clinical study.

Ophthalmology 2013 Apr 12;120(4):695-702. Epub 2012 Dec 12.

Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2012.09.035DOI Listing
April 2013

Trichostatin A inhibits transforming growth factor-β-induced reactive oxygen species accumulation and myofibroblast differentiation via enhanced NF-E2-related factor 2-antioxidant response element signaling.

Mol Pharmacol 2013 Mar 2;83(3):671-80. Epub 2013 Jan 2.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.1124/mol.112.081059DOI Listing
March 2013

Ring-shaped corneoscleral lamellar keratoplasty guided by high-definition optical coherence tomography and Scheimpflug imaging for severe Terrien's marginal corneal degeneration.

Graefes Arch Clin Exp Ophthalmol 2012 Dec 11;250(12):1795-801. Epub 2012 May 11.

Qingdao University Medical College, Qingdao, China.

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http://dx.doi.org/10.1007/s00417-012-2042-4DOI Listing
December 2012

Experimental efficacy of mycophenolate mofetil implant on high-risk corneal allograft rejection and its biocompatibility in the anterior chamber of rabbits.

J Ocul Pharmacol Ther 2012 Dec 30;28(6):609-17. Epub 2012 Jul 30.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, PR China.

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http://dx.doi.org/10.1089/jop.2012.0065DOI Listing
December 2012

Pluripotin enhances the expansion of rabbit limbal epithelial stem/progenitor cells in vitro.

Exp Eye Res 2012 Jul 30;100:52-8. Epub 2012 Apr 30.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China.

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http://dx.doi.org/10.1016/j.exer.2012.04.012DOI Listing
July 2012

Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and -9: an in vitro study.

Mol Vis 2011 24;17:3406-14. Epub 2011 Dec 24.

State Key Lab Cultivation Base, Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247170PMC
April 2012

Role of senescent fibroblasts on alkali-induced corneal neovascularization.

J Cell Physiol 2012 Mar;227(3):1148-56

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1002/jcp.22835DOI Listing
March 2012

The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death.

Proc Natl Acad Sci U S A 2011 Jul 5;108(29):12030-5. Epub 2011 Jul 5.

Department of Pathology and Laboratory of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.1101450108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141944PMC
July 2011

In vitro culture of human fetal corneal endothelial cells.

Graefes Arch Clin Exp Ophthalmol 2011 May 21;249(5):663-9. Epub 2010 Dec 21.

Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Qingdao, 266071, China.

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http://dx.doi.org/10.1007/s00417-010-1547-yDOI Listing
May 2011

Clinical features and surgical treatment of peripheral staphyloma.

Cornea 2011 Apr;30(4):395-9

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1097/ICO.0b013e3181f22b8eDOI Listing
April 2011

Features of corneal neovascularization and lymphangiogenesis induced by different etiological factors in mice.

Graefes Arch Clin Exp Ophthalmol 2011 Jan 17;249(1):55-67. Epub 2010 Jul 17.

The State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1007/s00417-010-1442-6DOI Listing
January 2011

Expression of MMP, HPSE, and FAP in stroma promoted corneal neovascularization induced by different etiological factors.

Curr Eye Res 2010 Nov;35(11):967-77

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.3109/02713683.2010.502294DOI Listing
November 2010

Establishment of a murine model of chronic corneal allograft dysfunction.

Graefes Arch Clin Exp Ophthalmol 2010 Oct 16;248(10):1437-45. Epub 2010 May 16.

State Key Lab Cultivation Base, Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, 5 Yanerdao Road, Qingdao, 266071, People's Republic of China.

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http://link.springer.com/10.1007/s00417-010-1403-0
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http://dx.doi.org/10.1007/s00417-010-1403-0DOI Listing
October 2010

Risk factors, clinical features, and outcomes of recurrent fungal keratitis after corneal transplantation.

Ophthalmology 2010 May 15;117(5):890-6. Epub 2010 Jan 15.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://linkinghub.elsevier.com/retrieve/pii/S016164200901175
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http://dx.doi.org/10.1016/j.ophtha.2009.10.004DOI Listing
May 2010

Modified deep lamellar keratoplasty for the treatment of advanced-stage keratoconus with steep curvature.

Ophthalmology 2010 Feb 6;117(2):226-31. Epub 2009 Dec 6.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2009.07.005DOI Listing
February 2010

Perioperative treatment and prognostic factors for penetrating keratoplasty in Acanthamoeba keratitis unresponsive to medical treatment.

Graefes Arch Clin Exp Ophthalmol 2009 Oct 9;247(10):1383-8. Epub 2009 May 9.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, 5 Yanerdao Road, Qingdao, China.

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http://link.springer.com/10.1007/s00417-009-1103-9
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http://dx.doi.org/10.1007/s00417-009-1103-9DOI Listing
October 2009

Role of extracellular phospholipase B of Candida albicans as a virulent factor in experimental keratomycosis.

Curr Eye Res 2009 Sep;34(9):761-8

The State Key Lab Cultivation Base, Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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September 2009

Penetrating keratoplasty with small-diameter and glycerin-cryopreserved grafts for eccentric corneal perforations.

Cornea 2009 Jul;28(6):631-7

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1097/ICO.0b013e318191b857DOI Listing
July 2009

Expression of fibroblast activation proteins in corneal stromal neovascularization.

Curr Eye Res 2009 Feb;34(2):112-7

Qingdao University Medical College, Qingdao, China.

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http://dx.doi.org/10.1080/02713680802607732DOI Listing
February 2009

Management of severe ocular burns with symblepharon.

Graefes Arch Clin Exp Ophthalmol 2009 Jan 3;247(1):101-6. Epub 2008 Sep 3.

State Key Lab Cultivation Base, Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1007/s00417-008-0934-0DOI Listing
January 2009

Clinical features of immune rejection after corneoscleral transplantation.

Am J Ophthalmol 2008 Nov 15;146(5):707-13. Epub 2008 Aug 15.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://www.sd-eh.com/download/drshi/008.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S000293940800441
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http://dx.doi.org/10.1016/j.ajo.2008.05.051DOI Listing
November 2008

Antifungal susceptibility for common pathogens of fungal keratitis in Shandong Province, China.

Am J Ophthalmol 2008 Aug 11;146(2):260-265. Epub 2008 Jun 11.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ajo.2008.04.019DOI Listing
August 2008

Combined penetrating keratoplasty and keratolimbal allograft transplantation in comparison with corneoscleral transplantation in the treatment of severe eye burns.

Clin Exp Ophthalmol 2008 Aug;36(6):501-7

State Key Lab Cultivation Base, Shandong Provincial Key Lab of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1111/j.1442-9071.2008.01802.xDOI Listing
August 2008

Hyphal growth patterns and recurrence of fungal keratitis after lamellar keratoplasty.

Ophthalmology 2008 Jun 24;115(6):983-7. Epub 2007 Oct 24.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2007.07.034DOI Listing
June 2008

Antifungal chemotherapy for fungal keratitis guided by in vivo confocal microscopy.

Graefes Arch Clin Exp Ophthalmol 2008 Apr 11;246(4):581-6. Epub 2007 Dec 11.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1007/s00417-007-0719-xDOI Listing
April 2008

Primary diseases of corneal perforation in Shandong Province, China: a 10-year retrospective study.

Am J Ophthalmol 2008 Apr 15;145(4):662-666. Epub 2008 Feb 15.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ajo.2007.12.020DOI Listing
April 2008

Treatment failure after lamellar keratoplasty for fungal keratitis.

Ophthalmology 2008 Jan 27;115(1):33-6. Epub 2007 Jun 27.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2007.03.072DOI Listing
January 2008

Long-term outcomes of photorefractive keratectomy in eyes with previous epikeratophakia for keratoconus.

Cornea 2007 Dec;26(10):1200-4

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ICO.0b013e31815654a5DOI Listing
December 2007

Prolongation of corneal allograft survival by CTLA4-FasL in a murine model.

Graefes Arch Clin Exp Ophthalmol 2007 Nov 31;245(11):1691-7. Epub 2007 May 31.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://link.springer.com/10.1007/s00417-007-0606-5
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http://dx.doi.org/10.1007/s00417-007-0606-5DOI Listing
November 2007

Indications of paediatric keratoplasty in north China.

Clin Exp Ophthalmol 2007 Nov;35(8):724-7

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1111/j.1442-9071.2007.01618.xDOI Listing
November 2007

Amniotic membrane transplantation combined with antiviral and steroid therapy for herpes necrotizing stromal keratitis.

Ophthalmology 2007 Aug 23;114(8):1476-81. Epub 2007 Mar 23.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2006.11.027DOI Listing
August 2007

Penetrating keratoplasty for corneal perforations in fungal keratitis.

Cornea 2007 Feb;26(2):158-62

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1097/01.ico.0000248381.24519.0dDOI Listing
February 2007

Spectrum of fungal keratitis in north China.

Ophthalmology 2006 Nov 28;113(11):1943-8. Epub 2006 Aug 28.

State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1016/j.ophtha.2006.05.035DOI Listing
November 2006

Sustained intraocular rapamycin delivery effectively prevents high-risk corneal allograft rejection and neovascularization in rabbits.

Invest Ophthalmol Vis Sci 2006 Aug;47(8):3339-44

School of Medicine, Qingdao University, China.

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http://dx.doi.org/10.1167/iovs.05-1425DOI Listing
August 2006

Intravitreal implantation of the biodegradable cyclosporin A drug delivery system for experimental chronic uveitis.

Graefes Arch Clin Exp Ophthalmol 2006 Apr 15;244(4):492-7. Epub 2005 Sep 15.

Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1007/s00417-005-0109-1DOI Listing
April 2006

FK506 in a biodegradable glycolide-co-clatide-co-caprolactone polymer for prolongation of corneal allograft survival.

Curr Eye Res 2005 Nov;30(11):969-76

Shandong Eye Institute, Qingdao, China.

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http://dx.doi.org/10.1080/02713680500320752DOI Listing
November 2005

Roles of adherence and matrix metalloproteinases in growth patterns of fungal pathogens in cornea.

Curr Eye Res 2005 Aug;30(8):613-20

Shandong Eye Institute, Qingdao, People's Republic of China.

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http://dx.doi.org/10.1080/02713680590968196DOI Listing
August 2005

Roles of tumor necrosis factor-related apoptosis-inducing ligand in corneal transplantation.

Transplantation 2003 Dec;76(11):1556-9

Shandong Eye Institute and Hospital, Qingdao, China.

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http://dx.doi.org/10.1097/01.TP.0000089242.86443.40DOI Listing
December 2003

Experimental corneal allograft rejection.

Immunol Res 2002 ;25(1):1-26

Lions Eye Research Laboratories, LSU Eye Center, LSU Health Sciences Center, New Orleans, LA 70112-2234, USA.

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http://dx.doi.org/10.1385/IR:25:1:01DOI Listing
September 2002

[Prolongation of corneal allograft survival in mice with a cyclosporine drug delivery system implant].

Zhonghua Yan Ke Za Zhi 2002 Aug;38(8):502-5

Shandong Eye Institute and Hospital, Qingdao 266071, China.

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August 2002

Experimental study on the effect of cyclosporine A drug delivery system implanted in anterior chamber on high-risk corneal graft rejection.

Zhonghua Yan Ke Za Zhi 2002 Jul;38(7):422-5

Shandong Eye Institute and Hospital, Qingdao 266071, China (Email:

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July 2002

[Treatment of fungal keratitis with partial lamellar keratoplasty].

Zhonghua Yan Ke Za Zhi 2002 Jun;38(6):347-50

Shandong Eye Institute & Hospital, Qingdao 266071 China.

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June 2002

[Observation on healing process of corneal lens after epikeratophakia with confocal microscopy].

Zhonghua Yan Ke Za Zhi 2002 May;38(5):295-7

Shandong Eye Institute & Hospital, Qingdao 266071, China.

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May 2002

Lamellar keratoplasty for the treatment of fungal keratitis.

Cornea 2002 Jan;21(1):33-7

Shandong Eye Institute and Hospital, Qingdao, People's Republic of China.

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January 2002

Effect of a cyclosporine A delivery system in corneal transplantation.

Chin Med J (Engl) 2002 Jan;115(1):110-3

Shandong Eye Institute, Qingdao 266071, China.

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January 2002

[Retrospective analysis of misdiagnosed amoebic keratitis].

Zhonghua Yan Ke Za Zhi 2002 Jan;38(1):21-3

Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao 266071, China.

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January 2002