Weiwen Zhang

Weiwen Zhang

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Prediction, docking study and molecular simulation of 3D DNA aptamers to their targets of endocrine disrupting chemicals.

J Biomol Struct Dyn 2019 Oct 10;37(16):4274-4282. Epub 2019 Jan 10.

School of Public Health, Guangzhou Medical University , Guangzhou , P. R. China.

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https://www.tandfonline.com/doi/full/10.1080/07391102.2018.1
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http://dx.doi.org/10.1080/07391102.2018.1547222DOI Listing
October 2019

Omics Analysis for Dinoflagellates Biology Research.

Microorganisms 2019 Aug 23;7(9). Epub 2019 Aug 23.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China.

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http://dx.doi.org/10.3390/microorganisms7090288DOI Listing
August 2019

Metabolic engineering to enhance biosynthesis of both docosahexaenoic acid and odd-chain fatty acids in sp. S31.

Biotechnol Biofuels 2019 8;12:141. Epub 2019 Jun 8.

1Center for Biosafety Research and Strategy, Tianjin University, Tianjin, People's Republic of China.

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http://dx.doi.org/10.1186/s13068-019-1484-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555965PMC
June 2019

Superior Wear Resistance in EBM-Processed TC4 Alloy Compared with SLM and Forged Samples.

Materials (Basel) 2019 Mar 7;12(5). Epub 2019 Mar 7.

Department of Mechanical and Industrial Engineering, Tallinn University of Technology, Ehitajete tee 5, 19086 Tallinn, Estonia.

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http://dx.doi.org/10.3390/ma12050782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427751PMC
March 2019

Toolboxes for cyanobacteria: Recent advances and future direction.

Biotechnol Adv 2018 Jul - Aug;36(4):1293-1307. Epub 2018 May 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, PR China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S07349750183007
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http://dx.doi.org/10.1016/j.biotechadv.2018.04.007DOI Listing
February 2019

Ethical dilemma of identity disclosure faced by medical students in clinical clerkships: A nationwide multicenter study in China.

PLoS One 2018 11;13(7):e0200335. Epub 2018 Jul 11.

Department of Medical Education, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200335PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040732PMC
January 2019

Transporters Related to Stress Responses and Their Potential Application in Synechocystis sp. PCC 6803.

Adv Exp Med Biol 2018;1080:27-53

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.1007/978-981-13-0854-3_2DOI Listing
January 2019

Discovery and Application of Stress-Responsive sRNAs in Cyanobacteria.

Adv Exp Med Biol 2018;1080:55-74

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.1007/978-981-13-0854-3_3DOI Listing
January 2019

Direct Photosynthetic Production of Plastic Building Block Chemicals from CO.

Adv Exp Med Biol 2018;1080:215-238

Center for Biosafety Research and Strategy, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.1007/978-981-13-0854-3_9DOI Listing
January 2019

Rewiring metabolic network by chemical modulator based laboratory evolution doubles lipid production in Crypthecodinium cohnii.

Metab Eng 2019 01 26;51:88-98. Epub 2018 Oct 26.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, PR China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, PR China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967176183026
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http://dx.doi.org/10.1016/j.ymben.2018.10.004DOI Listing
January 2019

Editorial: The Individual Microbe: Single-Cell Analysis and Agent-Based Modelling.

Front Microbiol 2018 21;9:2825. Epub 2018 Nov 21.

Laboratory of Synthetic Microbiology, Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.3389/fmicb.2018.02825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258959PMC
November 2018

Membrane-Located Expression of Thioesterase From Enhances Free Fatty Acid Production With Decreased Toxicity in sp. PCC6803.

Front Microbiol 2018 27;9:2842. Epub 2018 Nov 27.

Bio-X-Renji Hospital Research Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.3389/fmicb.2018.02842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277518PMC
November 2018

Nitrogen Feeding Strategies and Metabolomic Analysis To Alleviate High-Nitrogen Inhibition on Docosahexaenoic Acid Production in Crypthecodinium cohnii.

J Agric Food Chem 2018 Oct 1;66(40):10640-10650. Epub 2018 Oct 1.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology , Tianjin University , Tianjin 300072 , PR China.

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http://pubs.acs.org/doi/10.1021/acs.jafc.8b03634
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http://dx.doi.org/10.1021/acs.jafc.8b03634DOI Listing
October 2018

Screening of chemical modulators for lipid accumulation in Schizochytrium sp. S31.

Bioresour Technol 2018 Jul 29;260:124-129. Epub 2018 Mar 29.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S09608524183046
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http://dx.doi.org/10.1016/j.biortech.2018.03.104DOI Listing
July 2018

Heavy metal and δC value variations and characterization of dissolved organic matter (DOM) during vermicomposting of pig manure amended with C-labeled rice straw.

Environ Sci Pollut Res Int 2018 Jul 10;25(20):20169-20178. Epub 2018 May 10.

Key Laboratory of Hangzhou City for Ecosystem Protection and Restoration, Hangzhou Normal University, Hangzhou, 310036, China.

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http://dx.doi.org/10.1007/s11356-018-2016-0DOI Listing
July 2018

Development and optimization of genetic toolboxes for a fast-growing cyanobacterium Synechococcus elongatus UTEX 2973.

Metab Eng 2018 07 6;48:163-174. Epub 2018 Jun 6.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

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http://dx.doi.org/10.1016/j.ymben.2018.06.002DOI Listing
July 2018

Adaptive laboratory evolution of cadmium tolerance in sp. PCC 6803.

Biotechnol Biofuels 2018 24;11:205. Epub 2018 Jul 24.

1Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

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http://dx.doi.org/10.1186/s13068-018-1205-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058365PMC
July 2018

Regulation Mechanism Mediated by -Encoded sRNA Nc117 in Short Chain Alcohols Tolerance in sp. PCC 6803.

Front Microbiol 2018 1;9:863. Epub 2018 May 1.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.3389/fmicb.2018.00863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946031PMC
May 2018

C Metabolic Flux Analysis of Enhanced Lipid Accumulation Modulated by Ethanolamine in .

Front Microbiol 2018 15;9:956. Epub 2018 May 15.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

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http://journal.frontiersin.org/article/10.3389/fmicb.2018.00
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http://dx.doi.org/10.3389/fmicb.2018.00956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963191PMC
May 2018

Genetic Engineering of to Increase Growth and Lipid Accumulation.

Front Microbiol 2018 19;9:492. Epub 2018 Mar 19.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.3389/fmicb.2018.00492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868476PMC
March 2018

Re-direction of carbon flux to key precursor malonyl-CoA via artificial small RNAs in photosynthetic sp. PCC 6803.

Biotechnol Biofuels 2018 5;11:26. Epub 2018 Feb 5.

1Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

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http://dx.doi.org/10.1186/s13068-018-1032-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798194PMC
February 2018

Microstructure Evolution during Dissimilar Friction Stir Welding of AA7003-T4 and AA6060-T4.

Materials (Basel) 2018 Feb 27;11(3). Epub 2018 Feb 27.

National Engineering Research Center of Near-net shape Forming for Metallic Materials, South China University of Technology, Guangzhou 510640, China.

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http://dx.doi.org/10.3390/ma11030342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872921PMC
February 2018

Co-overexpression of response regulator genes slr1037 and sll0039 improves tolerance of Synechocystis sp. PCC 6803 to 1-butanol.

Bioresour Technol 2017 Dec 4;245(Pt B):1476-1483. Epub 2017 May 4.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, PR China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, PR China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

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http://dx.doi.org/10.1016/j.biortech.2017.04.112DOI Listing
December 2017

Detergent-Insoluble Proteome Analysis Revealed Aberrantly Aggregated Proteins in Human Preeclampsia Placentas.

J Proteome Res 2017 12 17;16(12):4468-4480. Epub 2017 Oct 17.

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University , 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, China.

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http://dx.doi.org/10.1021/acs.jproteome.7b00352DOI Listing
December 2017

From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality.

Front Microbiol 2017 27;8:2299. Epub 2017 Nov 27.

Civil and Environmental Engineering Department, Marine and Environmental Sciences Department, Bioengineering Department, Northeastern University, Boston, MA, United States.

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http://dx.doi.org/10.3389/fmicb.2017.02299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711835PMC
November 2017

Influence of Ultrasonic Surface Rolling on Microstructure and Wear Behavior of Selective Laser Melted Ti-6Al-4V Alloy.

Materials (Basel) 2017 Oct 19;10(10). Epub 2017 Oct 19.

National Engineering Research Center of Near-Net Shape Forming for Metallic Materials, South China University of Technology, Guangzhou 510640, China.

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http://www.mdpi.com/1996-1944/10/10/1203
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http://dx.doi.org/10.3390/ma10101203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667009PMC
October 2017

Luminescence materials for pH and oxygen sensing in microbial cells - structures, optical properties, and biological applications.

Crit Rev Biotechnol 2017 Sep 15;37(6):723-738. Epub 2016 Sep 15.

b Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology , Tianjin University , Tianjin , P.R. China.

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http://dx.doi.org/10.1080/07388551.2016.1223011DOI Listing
September 2017

Improving the Mechanical Properties of Cu-15Ni-8Sn Alloys by Addition of Titanium.

Materials (Basel) 2017 Sep 6;10(9). Epub 2017 Sep 6.

Guangdong Key Laboratory for Processing and Forming of Advanced Metallic Materials, South China University of Technology, Guangzhou 510640, China.

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http://dx.doi.org/10.3390/ma10091038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615693PMC
September 2017

Tools for Genomic and Transcriptomic Analysis of Microbes at Single-Cell Level.

Front Microbiol 2017 20;8:1831. Epub 2017 Sep 20.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin UniversityTianjin, China.

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http://dx.doi.org/10.3389/fmicb.2017.01831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611438PMC
September 2017

Screening and transcriptomic analysis of Crypthecodinium cohnii mutants with high growth and lipid content using the acetyl-CoA carboxylase inhibitor sethoxydim.

Appl Microbiol Biotechnol 2017 Aug 3;101(15):6179-6191. Epub 2017 Jul 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-017-8397-zDOI Listing
August 2017

Quantitative Proteomics Reveals Potential Crosstalk between a Small RNA CoaR and a Two-Component Regulator Slr1037 in Synechocystis sp. PCC6803.

J Proteome Res 2017 08 14;16(8):2954-2963. Epub 2017 Jul 14.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University , Tianjin 300072, P. R. China.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.7b00243
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http://dx.doi.org/10.1021/acs.jproteome.7b00243DOI Listing
August 2017

Identification of a New Target of the Response Regulator Sll0649 Involving Cadmium Tolerance in sp. PCC 6803.

Front Microbiol 2017 15;8:1582. Epub 2017 Aug 15.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin UniversityTianjin, China.

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http://dx.doi.org/10.3389/fmicb.2017.01582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559466PMC
August 2017

Metabolomic analysis and lipid accumulation in a glucose tolerant Crypthecodinium cohnii strain obtained by adaptive laboratory evolution.

Bioresour Technol 2017 Jul 12;235:87-95. Epub 2017 Mar 12.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science & Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

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http://dx.doi.org/10.1016/j.biortech.2017.03.049DOI Listing
July 2017

Crosstalk of two-component signal transduction systems in regulating central carbohydrate and energy metabolism during autotrophic and photomixotrophic growth of Synechocystis sp. PCC 6803.

Integr Biol (Camb) 2017 05;9(5):485-496

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P. R. China.

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http://dx.doi.org/10.1039/c7ib00049aDOI Listing
May 2017

Systematic and functional identification of small non-coding RNAs associated with exogenous biofuel stress in cyanobacterium sp. PCC 6803.

Biotechnol Biofuels 2017 7;10:57. Epub 2017 Mar 7.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

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http://dx.doi.org/10.1186/s13068-017-0743-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341163PMC
March 2017

Versatility of hydrocarbon production in cyanobacteria.

Appl Microbiol Biotechnol 2017 Feb 28;101(3):905-919. Epub 2016 Dec 28.

Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao, 266101, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-016-8064-9DOI Listing
February 2017

A novel small RNA CoaR regulates coenzyme A biosynthesis and tolerance of sp. PCC6803 to 1-butanol possibly via promoter-directed transcriptional silencing.

Biotechnol Biofuels 2017 20;10:42. Epub 2017 Feb 20.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

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http://dx.doi.org/10.1186/s13068-017-0727-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319066PMC
February 2017

Functional Diversity of Transcriptional Regulators in the Cyanobacterium sp. PCC 6803.

Front Microbiol 2017 21;8:280. Epub 2017 Feb 21.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin UniversityTianjin, China; Key Laboratory of Systems Bioengineering - Ministry of Education, Tianjin UniversityTianjin, China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and EngineeringTianjin, China; Center for Biosafety Research and Strategy, Tianjin UniversityTianjin, China.

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http://dx.doi.org/10.3389/fmicb.2017.00280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318462PMC
February 2017

Integrated Analysis of Transcriptomic and Proteomic Datasets Reveals Information on Protein Expressivity and Factors Affecting Translational Efficiency.

Methods Mol Biol 2016 ;1375:123-36

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://dx.doi.org/10.1007/7651_2015_242DOI Listing
December 2016

Proteomic and metabolomic analyses reveal metabolic responses to 3-hydroxypropionic acid synthesized internally in cyanobacterium sp. PCC 6803.

Biotechnol Biofuels 2016 6;9:209. Epub 2016 Oct 6.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072 People's Republic of China ; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, People's Republic of China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, People's Republic of China.

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http://dx.doi.org/10.1186/s13068-016-0627-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053081PMC
October 2016

Measuring gene expression in single bacterial cells: recent advances in methods and micro-devices.

Crit Rev Biotechnol 2015 7;35(4):448-60. Epub 2014 Apr 7.

a Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University , Tempe , AZ , USA and.

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http://dx.doi.org/10.3109/07388551.2014.899556DOI Listing
September 2016

Transcriptional regulator PrqR plays a negative role in glucose metabolism and oxidative stress acclimation in Synechocystis sp. PCC 6803.

Sci Rep 2016 09 1;6:32507. Epub 2016 Sep 1.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, P.R. China.

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http://dx.doi.org/10.1038/srep32507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007503PMC
September 2016

Metabolic dynamics of Desulfovibrio vulgaris biofilm grown on a steel surface.

Biofouling 2016 08;32(7):725-36

a Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology , Tianjin University , Tianjin , PR China.

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http://dx.doi.org/10.1080/08927014.2016.1193166DOI Listing
August 2016

Roles of two-component system AfsQ1/Q2 in regulating biosynthesis of the yellow-pigmented coelimycin P2 in Streptomyces coelicolor.

FEMS Microbiol Lett 2016 08 15;363(15). Epub 2016 Jun 15.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, PR China Shanghai Collaborative Innovation Center for Biomanufacturing Technology, Shanghai 200237, PR China

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http://dx.doi.org/10.1093/femsle/fnw160DOI Listing
August 2016

EPCs enhance angiogenesis in renal regeneration.

Oncotarget 2016 Jul;7(29):44941-44949

Institute of Bioscaffold Transplantation and Immunology, Wenzhou Medical University, Wenzhou, China.

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http://dx.doi.org/10.18632/oncotarget.10377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216696PMC
July 2016

In Vitro Corrosion Study of Friction Stir Processed WE43 Magnesium Alloy in a Simulated Body Fluid.

Materials (Basel) 2016 Jul 7;9(7). Epub 2016 Jul 7.

National Engineering Research Center of Near-Net Shape Forming for Metallic Materials, South China University of Technology, Guangzhou 510640, Guangdong, China.

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http://dx.doi.org/10.3390/ma9070542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456840PMC
July 2016

Fatty acid and metabolomic profiling approaches differentiate heterotrophic and mixotrophic culture conditions in a microalgal food supplement 'Euglena'.

BMC Biotechnol 2016 06 2;16(1):49. Epub 2016 Jun 2.

Shenzhen Key Laboratory of Marine Bioresource & Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, College of Life Science, Shenzhen University, Shenzhen, 518060, People's Republic of China.

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http://dx.doi.org/10.1186/s12896-016-0279-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890288PMC
June 2016

Basal cell adenoma of the parotid gland: clinical and pathological findings in 29 cases.

Int J Clin Exp Pathol 2015 1;8(3):2899-908. Epub 2015 Mar 1.

Department of Otolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine Shanghai 200092, China ; Ear Institute, Shanghai Jiaotong University School of Medicine Shanghai 200092, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440107PMC
May 2016

Microbial production of mammalian melatonin - a promising solution to melatonin industry.

Biotechnol J 2016 05 25;11(5):601-2. Epub 2016 Jan 25.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

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http://dx.doi.org/10.1002/biot.201500604DOI Listing
May 2016

Comparison of Transcriptional Heterogeneity of Eight Genes between Batch Desulfovibrio vulgaris Biofilm and Planktonic Culture at a Single-Cell Level.

Front Microbiol 2016 27;7:597. Epub 2016 Apr 27.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin UniversityTianjin, China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin UniversityTianjin, China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and EngineeringTianjin, China.

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http://journal.frontiersin.org/Article/10.3389/fmicb.2016.00
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http://dx.doi.org/10.3389/fmicb.2016.00597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847118PMC
May 2016

Cyanobacterial chassis engineering for enhancing production of biofuels and chemicals.

Appl Microbiol Biotechnol 2016 Apr 17;100(8):3401-13. Epub 2016 Feb 17.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-016-7374-2DOI Listing
April 2016

Biosynthesis of platform chemical 3-hydroxypropionic acid (3-HP) directly from CO2 in cyanobacterium Synechocystis sp. PCC 6803.

Metab Eng 2016 Mar 9;34:60-70. Epub 2015 Nov 9.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P.R. China; Synbio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, P.R. China. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2015.10.008DOI Listing
March 2016

A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin.

Appl Environ Microbiol 2016 01 30;82(2):467-77. Epub 2015 Oct 30.

Department of Biological Sciences, Ohio University, Athens, Ohio, USA

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http://dx.doi.org/10.1128/AEM.02517-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711141PMC
January 2016

Premethylation of foreign DNA improves integrative transformation efficiency in Synechocystis sp. strain PCC 6803.

Appl Environ Microbiol 2015 Dec 9;81(24):8500-6. Epub 2015 Oct 9.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, Arizona, USA

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http://dx.doi.org/10.1128/AEM.02575-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644663PMC
December 2015

RNA-seq based transcriptomic analysis of single bacterial cells.

Integr Biol (Camb) 2015 Nov;7(11):1466-76

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P. R. China. and Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P. R. China.

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http://dx.doi.org/10.1039/c5ib00191aDOI Listing
November 2015

Heterologous xylose isomerase pathway and evolutionary engineering improve xylose utilization in Saccharomyces cerevisiae.

Front Microbiol 2015 21;6:1165. Epub 2015 Oct 21.

Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University Tianjin, China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University Tianjin, China.

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http://dx.doi.org/10.3389/fmicb.2015.01165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612707PMC
November 2015

Early interventional therapy for acute massive pulmonary embolism guided by minimally invasive hemodynamic monitoring.

Int J Clin Exp Med 2015 15;8(8):14011-7. Epub 2015 Aug 15.

Department of Surgery, Quzhou People's Hospital, Zhejiang University Quzhou, Zhejiang, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613045PMC
November 2015

Identification and metabolomic analysis of chemical modulators for lipid accumulation in Crypthecodinium cohnii.

Bioresour Technol 2015 Sep 18;191:362-8. Epub 2015 Mar 18.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; SynBio Platform, Collaborative Innovation Center of Chemical Science & Engineering, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2015.03.068DOI Listing
September 2015

A global network-based protocol for functional inference of hypothetical proteins in Synechocystis sp. PCC 6803.

J Microbiol Methods 2015 Sep 3;116:44-52. Epub 2015 Jul 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; SynBio Platform, Collaborative Innovation Center of Chemical Science & Engineering, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.mimet.2015.06.013DOI Listing
September 2015

Identification of a transporter Slr0982 involved in ethanol tolerance in cyanobacterium Synechocystis sp. PCC 6803.

Front Microbiol 2015 18;6:487. Epub 2015 May 18.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University Tianjin, China ; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University Tianjin, China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin, China.

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http://dx.doi.org/10.3389/fmicb.2015.00487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440267PMC
June 2015

Marchiafava-Bignami disease with rare etiology: A case report.

Exp Ther Med 2015 Apr 5;9(4):1515-1517. Epub 2015 Feb 5.

The Second Department of Neurology, Harrison International Peace Hospital, Hengshui, Hebei 053000, P.R. China.

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http://dx.doi.org/10.3892/etm.2015.2263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353765PMC
April 2015

Metabolomic analysis reveals functional overlapping of three signal transduction proteins in regulating ethanol tolerance in cyanobacterium Synechocystis sp. PCC 6803.

Mol Biosyst 2015 Mar 11;11(3):770-82. Epub 2014 Dec 11.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P. R. China.

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http://dx.doi.org/10.1039/c4mb00651hDOI Listing
March 2015

Chemicals to enhance microalgal growth and accumulation of high-value bioproducts.

Front Microbiol 2015 17;6:56. Epub 2015 Feb 17.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University Tianjin, China ; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University Tianjin, China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin, China.

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http://dx.doi.org/10.3389/fmicb.2015.00056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330911PMC
March 2015

Elucidating butanol tolerance mediated by a response regulator Sll0039 in Synechocystis sp. PCC 6803 using a metabolomic approach.

Appl Microbiol Biotechnol 2015 Feb 21;99(4):1845-57. Epub 2015 Jan 21.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://link.springer.com/10.1007/s00253-015-6374-y
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http://dx.doi.org/10.1007/s00253-015-6374-yDOI Listing
February 2015

A transcriptional regulator Sll0794 regulates tolerance to biofuel ethanol in photosynthetic Synechocystis sp. PCC 6803.

Mol Cell Proteomics 2014 Dec 19;13(12):3519-32. Epub 2014 Sep 19.

From the ‡Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China; §Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P.R. China; ¶Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, P.R. China;

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http://dx.doi.org/10.1074/mcp.M113.035675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256502PMC
December 2014

Metabolomic analysis reveals mechanism of antioxidant butylated hydroxyanisole on lipid accumulation in Crypthecodinium cohnii.

J Agric Food Chem 2014 Dec 11;62(51):12477-84. Epub 2014 Dec 11.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University , Tianjin 300072, P.R. China.

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http://dx.doi.org/10.1021/jf503671mDOI Listing
December 2014

Single-cell analysis reveals gene-expression heterogeneity in syntrophic dual-culture of Desulfovibrio vulgaris with Methanosarcina barkeri.

Sci Rep 2014 Dec 15;4:7478. Epub 2014 Dec 15.

1] Laboratory of Synthetic Microbiology, School of Chemical Engineering &Technology, Tianjin University, Tianjin 300072, P.R. China [2] Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, P.R. China [3] SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), 300072, P.R. China.

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http://www.nature.com/articles/srep07478
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http://dx.doi.org/10.1038/srep07478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265775PMC
December 2014

Engineering biofuel tolerance in non-native producing microorganisms.

Biotechnol Adv 2014 Mar-Apr;32(2):541-8. Epub 2014 Feb 13.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biotechadv.2014.02.001DOI Listing
November 2014

Metabolomic basis of laboratory evolution of butanol tolerance in photosynthetic Synechocystis sp. PCC 6803.

Microb Cell Fact 2014 Nov 1;13:151. Epub 2014 Nov 1.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, P.R. China.

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http://dx.doi.org/10.1186/s12934-014-0151-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234862PMC
November 2014

Protein Network Signatures Associated with Exogenous Biofuels Treatments in Cyanobacterium Synechocystis sp. PCC 6803.

Front Bioeng Biotechnol 2014 3;2:48. Epub 2014 Nov 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University , Tianjin , China ; Key Laboratory of Systems Bioengineering, Ministry of Education of China , Tianjin , China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering , Tianjin , China.

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http://journal.frontiersin.org/article/10.3389/fbioe.2014.00
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http://dx.doi.org/10.3389/fbioe.2014.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217553PMC
November 2014

Metabolomic and network analysis of astaxanthin-producing Haematococcus pluvialis under various stress conditions.

Bioresour Technol 2014 Oct 10;170:522-529. Epub 2014 Aug 10.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.biortech.2014.08.018DOI Listing
October 2014

Bulk TiB₂-Based Ceramic Composites with Improved Mechanical Property Using Fe-Ni-Ti-Al as a Sintering Aid.

Materials (Basel) 2014 Oct 21;7(10):7105-7117. Epub 2014 Oct 21.

School of Engineering, Edith Cowan University, 270 Joondalup Drive, Joondalup, Perth, WA 6027, Australia.

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http://dx.doi.org/10.3390/ma7107105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5456019PMC
October 2014

Integrated proteomic and metabolomic characterization of a novel two-component response regulator Slr1909 involved in acid tolerance in Synechocystis sp. PCC 6803.

J Proteomics 2014 Sep 3;109:76-89. Epub 2014 Jul 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.06.021DOI Listing
September 2014

Synthetic biology applications in industrial microbiology.

Front Microbiol 2014 26;5:451. Epub 2014 Aug 26.

Department of Chemical Engineering, School for Engineering of Matter, Transport, and Energy, Arizona State University Tempe, AZ, USA.

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http://journal.frontiersin.org/article/10.3389/fmicb.2014.00
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http://dx.doi.org/10.3389/fmicb.2014.00451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143612PMC
September 2014

An orphan two-component response regulator Slr1588 involves salt tolerance by directly regulating synthesis of compatible solutes in photosynthetic Synechocystis sp. PCC 6803.

Mol Biosyst 2014 Jul 9;10(7):1765-74. Epub 2014 Apr 9.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China.

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http://dx.doi.org/10.1039/c4mb00095aDOI Listing
July 2014

Single-cell analysis reveals early manifestation of cancerous phenotype in pre-malignant esophageal cells.

PLoS One 2013 8;8(10):e75365. Epub 2013 Oct 8.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075365PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792915PMC
June 2014

Metabolomic analysis of the salt-sensitive mutants reveals changes in amino acid and fatty acid composition important to long-term salt stress in Synechocystis sp. PCC 6803.

Funct Integr Genomics 2014 Jun 19;14(2):431-40. Epub 2014 Mar 19.

Laboratory of Synthetic Microbiology, School of Chemical Engineering Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://dx.doi.org/10.1007/s10142-014-0370-7DOI Listing
June 2014

Butanol tolerance regulated by a two-component response regulator Slr1037 in photosynthetic Synechocystis sp. PCC 6803.

Biotechnol Biofuels 2014 11;7:89. Epub 2014 Jun 11.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China ; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P.R. China ; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, P.R. China.

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http://dx.doi.org/10.1186/1754-6834-7-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057619PMC
June 2014

An orphan response regulator Sll0649 involved in cadmium tolerance and metal homeostasis in photosynthetic Synechocystis sp. PCC 6803.

J Proteomics 2014 May 3;103:87-102. Epub 2014 Apr 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.03.029DOI Listing
May 2014

Proteomic analysis reveals complex metabolic regulation in Saccharomyces cerevisiae cells against multiple inhibitors stress.

Appl Microbiol Biotechnol 2014 Mar 19;98(5):2207-21. Epub 2014 Jan 19.

Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://dx.doi.org/10.1007/s00253-014-5519-8DOI Listing
March 2014

Global metabolomic and network analysis of Escherichia coli responses to exogenous biofuels.

J Proteome Res 2013 Nov 24;12(11):5302-12. Epub 2013 Sep 24.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, and Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University , Tianjin 300072, P. R. China.

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http://dx.doi.org/10.1021/pr400640uDOI Listing
November 2013

Complementary iTRAQ proteomics and RNA-seq transcriptomics reveal multiple levels of regulation in response to nitrogen starvation in Synechocystis sp. PCC 6803.

Mol Biosyst 2013 Oct;9(10):2565-74

School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China.

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http://dx.doi.org/10.1039/c3mb70188cDOI Listing
October 2013

Integrated metagenomic and metatranscriptomic analyses of microbial communities in the meso- and bathypelagic realm of north pacific ocean.

Mar Drugs 2013 Oct 11;11(10):3777-801. Epub 2013 Oct 11.

Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe, AZ 85287-6501, USA.

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http://dx.doi.org/10.3390/md11103777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826135PMC
October 2013

Integrated proteomic and transcriptomic analysis reveals novel genes and regulatory mechanisms involved in salt stress responses in Synechocystis sp. PCC 6803.

Appl Microbiol Biotechnol 2013 Sep 8;97(18):8253-64. Epub 2013 Aug 8.

School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

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http://link.springer.com/10.1007/s00253-013-5139-8
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http://dx.doi.org/10.1007/s00253-013-5139-8DOI Listing
September 2013

[Engineering photosynthetic cyanobacterial chassis: a review].

Sheng Wu Gong Cheng Xue Bao 2013 Aug;29(8):1086-99

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August 2013

Integrated OMICS guided engineering of biofuel butanol-tolerance in photosynthetic Synechocystis sp. PCC 6803.

Biotechnol Biofuels 2013 Jul 25;6(1):106. Epub 2013 Jul 25.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P,R, China.

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http://dx.doi.org/10.1186/1754-6834-6-106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726282PMC
July 2013

Monitoring the single-cell stress response of the diatom Thalassiosira pseudonana by quantitative real-time reverse transcription-PCR.

Appl Environ Microbiol 2013 Mar 11;79(6):1850-8. Epub 2013 Jan 11.

Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

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http://dx.doi.org/10.1128/AEM.03399-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592218PMC
March 2013

Engineering cyanobacteria for photosynthetic production of 3-hydroxybutyrate directly from CO2.

Metab Eng 2013 Mar 16;16:68-77. Epub 2013 Jan 16.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ 85287-6501, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109671761300004
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http://dx.doi.org/10.1016/j.ymben.2013.01.001DOI Listing
March 2013

Cross-species transcriptional network analysis reveals conservation and variation in response to metal stress in cyanobacteria.

BMC Genomics 2013 Feb 19;14:112. Epub 2013 Feb 19.

School of Chemical Engineering & Technology, Tianjin University, 300072, Tianjin, People's Republic of China.

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http://dx.doi.org/10.1186/1471-2164-14-112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598940PMC
February 2013

Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor.

Mol Microbiol 2013 Jan 19;87(1):30-48. Epub 2012 Nov 19.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

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http://dx.doi.org/10.1111/mmi.12080DOI Listing
January 2013

Reconstruction of distal limb defects with the free medial sural artery perforator flap.

Plast Reconstr Surg 2013 Jan;131(1):95-105

Department of Hand Surgery, Ningbo Sixth Hosspital, China.

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http://dx.doi.org/10.1097/PRS.0b013e3182729e3cDOI Listing
January 2013

Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165, associated with honeybees.

J Bacteriol 2012 Nov;194(22):6358-9

School of Chemical Engineering & Technology, Tianjin University, Tianjin, People's Republic of China.

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http://jb.asm.org/cgi/doi/10.1128/JB.01522-12
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http://dx.doi.org/10.1128/JB.01522-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486387PMC
November 2012