Weiwen Zhang

Weiwen Zhang

UNVERIFIED PROFILE

Are you Weiwen Zhang?   Register this Author

Register author
Weiwen Zhang

Weiwen Zhang

Publications by authors named "Weiwen Zhang"

Are you Weiwen Zhang?   Register this Author

100Publications

-Reads

Screening of chemical modulators for lipid accumulation in Schizochytrium sp. S31.

Bioresour Technol 2018 Jul 29;260:124-129. Epub 2018 Mar 29.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

View Article
July 2018

Heavy metal and δC value variations and characterization of dissolved organic matter (DOM) during vermicomposting of pig manure amended with C-labeled rice straw.

Environ Sci Pollut Res Int 2018 Jul 10;25(20):20169-20178. Epub 2018 May 10.

Key Laboratory of Hangzhou City for Ecosystem Protection and Restoration, Hangzhou Normal University, Hangzhou, 310036, China.

View Article
July 2018

Development and optimization of genetic toolboxes for a fast-growing cyanobacterium Synechococcus elongatus UTEX 2973.

Metab Eng 2018 Jul 6;48:163-174. Epub 2018 Jun 6.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

View Article
July 2018

Ethical dilemma of identity disclosure faced by medical students in clinical clerkships: A nationwide multicenter study in China.

PLoS One 2018 11;13(7):e0200335. Epub 2018 Jul 11.

Department of Medical Education, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China.

View Article
July 2018

Adaptive laboratory evolution of cadmium tolerance in sp. PCC 6803.

Biotechnol Biofuels 2018 24;11:205. Epub 2018 Jul 24.

1Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

View Article
July 2018

Toolboxes for cyanobacteria: Recent advances and future direction.

Biotechnol Adv 2018 Jul - Aug;36(4):1293-1307. Epub 2018 May 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, PR China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

View Article
May 2018

Regulation Mechanism Mediated by -Encoded sRNA Nc117 in Short Chain Alcohols Tolerance in sp. PCC 6803.

Front Microbiol 2018 1;9:863. Epub 2018 May 1.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.

View Article
May 2018

C Metabolic Flux Analysis of Enhanced Lipid Accumulation Modulated by Ethanolamine in .

Front Microbiol 2018 15;9:956. Epub 2018 May 15.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

View Article
May 2018

Genetic Engineering of to Increase Growth and Lipid Accumulation.

Front Microbiol 2018 19;9:492. Epub 2018 Mar 19.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.

View Article
March 2018

Re-direction of carbon flux to key precursor malonyl-CoA via artificial small RNAs in photosynthetic sp. PCC 6803.

Biotechnol Biofuels 2018 5;11:26. Epub 2018 Feb 5.

1Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

View Article
February 2018

Microstructure Evolution during Dissimilar Friction Stir Welding of AA7003-T4 and AA6060-T4.

Materials (Basel) 2018 Feb 27;11(3). Epub 2018 Feb 27.

National Engineering Research Center of Near-net shape Forming for Metallic Materials, South China University of Technology, Guangzhou 510640, China.

View Article
February 2018

Transporters Related to Stress Responses and Their Potential Application in Synechocystis sp. PCC 6803.

Adv Exp Med Biol 2018 ;1080:27-53

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

View Article
January 2018

Discovery and Application of Stress-Responsive sRNAs in Cyanobacteria.

Adv Exp Med Biol 2018 ;1080:55-74

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

View Article
January 2018

Direct Photosynthetic Production of Plastic Building Block Chemicals from CO.

Adv Exp Med Biol 2018 ;1080:215-238

Center for Biosafety Research and Strategy, Tianjin University, Tianjin, China.

View Article
January 2018

Co-overexpression of response regulator genes slr1037 and sll0039 improves tolerance of Synechocystis sp. PCC 6803 to 1-butanol.

Bioresour Technol 2017 Dec 4;245(Pt B):1476-1483. Epub 2017 May 4.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, PR China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, PR China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

View Article
December 2017

Detergent-Insoluble Proteome Analysis Revealed Aberrantly Aggregated Proteins in Human Preeclampsia Placentas.

J Proteome Res 2017 Dec 17;16(12):4468-4480. Epub 2017 Oct 17.

Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University , 601 Huangpu Avenue West, Guangzhou, Guangdong 510632, China.

View Article
December 2017

From Genes to Ecosystems in Microbiology: Modeling Approaches and the Importance of Individuality.

Front Microbiol 2017 27;8:2299. Epub 2017 Nov 27.

Civil and Environmental Engineering Department, Marine and Environmental Sciences Department, Bioengineering Department, Northeastern University, Boston, MA, United States.

View Article
November 2017

Influence of Ultrasonic Surface Rolling on Microstructure and Wear Behavior of Selective Laser Melted Ti-6Al-4V Alloy.

Materials (Basel) 2017 Oct 19;10(10). Epub 2017 Oct 19.

National Engineering Research Center of Near-Net Shape Forming for Metallic Materials, South China University of Technology, Guangzhou 510640, China.

View Article
October 2017

Luminescence materials for pH and oxygen sensing in microbial cells - structures, optical properties, and biological applications.

Crit Rev Biotechnol 2017 Sep 15;37(6):723-738. Epub 2016 Sep 15.

b Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology , Tianjin University , Tianjin , P.R. China.

View Article
September 2017

Improving the Mechanical Properties of Cu-15Ni-8Sn Alloys by Addition of Titanium.

Materials (Basel) 2017 Sep 6;10(9). Epub 2017 Sep 6.

Guangdong Key Laboratory for Processing and Forming of Advanced Metallic Materials, South China University of Technology, Guangzhou 510640, China.

View Article
September 2017

Tools for Genomic and Transcriptomic Analysis of Microbes at Single-Cell Level.

Front Microbiol 2017 20;8:1831. Epub 2017 Sep 20.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin UniversityTianjin, China.

View Article
September 2017

Screening and transcriptomic analysis of Crypthecodinium cohnii mutants with high growth and lipid content using the acetyl-CoA carboxylase inhibitor sethoxydim.

Appl Microbiol Biotechnol 2017 Aug 3;101(15):6179-6191. Epub 2017 Jul 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
August 2017

Quantitative Proteomics Reveals Potential Crosstalk between a Small RNA CoaR and a Two-Component Regulator Slr1037 in Synechocystis sp. PCC6803.

J Proteome Res 2017 Aug 14;16(8):2954-2963. Epub 2017 Jul 14.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University , Tianjin 300072, P. R. China.

View Article
August 2017

Identification of a New Target of the Response Regulator Sll0649 Involving Cadmium Tolerance in sp. PCC 6803.

Front Microbiol 2017 15;8:1582. Epub 2017 Aug 15.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin UniversityTianjin, China.

View Article
August 2017

Metabolomic analysis and lipid accumulation in a glucose tolerant Crypthecodinium cohnii strain obtained by adaptive laboratory evolution.

Bioresour Technol 2017 Jul 12;235:87-95. Epub 2017 Mar 12.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science & Engineering, Tianjin, PR China; Center for Biosafety Research and Strategy, Tianjin University, Tianjin, PR China.

View Article
July 2017

Crosstalk of two-component signal transduction systems in regulating central carbohydrate and energy metabolism during autotrophic and photomixotrophic growth of Synechocystis sp. PCC 6803.

Integr Biol (Camb) 2017 05;9(5):485-496

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P. R. China.

View Article
May 2017

Systematic and functional identification of small non-coding RNAs associated with exogenous biofuel stress in cyanobacterium sp. PCC 6803.

Biotechnol Biofuels 2017 7;10:57. Epub 2017 Mar 7.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

View Article
March 2017

Versatility of hydrocarbon production in cyanobacteria.

Appl Microbiol Biotechnol 2017 Feb 28;101(3):905-919. Epub 2016 Dec 28.

Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, No. 189 Songling Road, Qingdao, 266101, People's Republic of China.

View Article
February 2017

A novel small RNA CoaR regulates coenzyme A biosynthesis and tolerance of sp. PCC6803 to 1-butanol possibly via promoter-directed transcriptional silencing.

Biotechnol Biofuels 2017 20;10:42. Epub 2017 Feb 20.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072 People's Republic of China.

View Article
February 2017

Functional Diversity of Transcriptional Regulators in the Cyanobacterium sp. PCC 6803.

Front Microbiol 2017 21;8:280. Epub 2017 Feb 21.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin UniversityTianjin, China; Key Laboratory of Systems Bioengineering - Ministry of Education, Tianjin UniversityTianjin, China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and EngineeringTianjin, China; Center for Biosafety Research and Strategy, Tianjin UniversityTianjin, China.

View Article
February 2017

Integrated Analysis of Transcriptomic and Proteomic Datasets Reveals Information on Protein Expressivity and Factors Affecting Translational Efficiency.

Methods Mol Biol 2016 ;1375:123-36

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
December 2016

Proteomic and metabolomic analyses reveal metabolic responses to 3-hydroxypropionic acid synthesized internally in cyanobacterium sp. PCC 6803.

Biotechnol Biofuels 2016 6;9:209. Epub 2016 Oct 6.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072 People's Republic of China ; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, People's Republic of China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, People's Republic of China.

View Article
October 2016

Measuring gene expression in single bacterial cells: recent advances in methods and micro-devices.

Crit Rev Biotechnol 2015 7;35(4):448-60. Epub 2014 Apr 7.

a Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University , Tempe , AZ , USA and.

View Article
September 2016

Transcriptional regulator PrqR plays a negative role in glucose metabolism and oxidative stress acclimation in Synechocystis sp. PCC 6803.

Sci Rep 2016 09 1;6:32507. Epub 2016 Sep 1.

Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200240, P.R. China.

View Article
September 2016

Metabolic dynamics of Desulfovibrio vulgaris biofilm grown on a steel surface.

Biofouling 2016 08;32(7):725-36

a Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology , Tianjin University , Tianjin , PR China.

View Article
August 2016

Roles of two-component system AfsQ1/Q2 in regulating biosynthesis of the yellow-pigmented coelimycin P2 in Streptomyces coelicolor.

FEMS Microbiol Lett 2016 08 15;363(15). Epub 2016 Jun 15.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, PR China Shanghai Collaborative Innovation Center for Biomanufacturing Technology, Shanghai 200237, PR China

View Article
August 2016

EPCs enhance angiogenesis in renal regeneration.

Oncotarget 2016 Jul;7(29):44941-44949

Institute of Bioscaffold Transplantation and Immunology, Wenzhou Medical University, Wenzhou, China.

View Article
July 2016

In Vitro Corrosion Study of Friction Stir Processed WE43 Magnesium Alloy in a Simulated Body Fluid.

Materials (Basel) 2016 Jul 7;9(7). Epub 2016 Jul 7.

National Engineering Research Center of Near-Net Shape Forming for Metallic Materials, South China University of Technology, Guangzhou 510640, Guangdong, China.

View Article
July 2016

Fatty acid and metabolomic profiling approaches differentiate heterotrophic and mixotrophic culture conditions in a microalgal food supplement 'Euglena'.

BMC Biotechnol 2016 06 2;16(1):49. Epub 2016 Jun 2.

Shenzhen Key Laboratory of Marine Bioresource & Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, College of Life Science, Shenzhen University, Shenzhen, 518060, People's Republic of China.

View Article
June 2016

Basal cell adenoma of the parotid gland: clinical and pathological findings in 29 cases.

Int J Clin Exp Pathol 2015 1;8(3):2899-908. Epub 2015 Mar 1.

Department of Otolaryngology-Head & Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine Shanghai 200092, China ; Ear Institute, Shanghai Jiaotong University School of Medicine Shanghai 200092, China.

View Article
May 2016

Microbial production of mammalian melatonin - a promising solution to melatonin industry.

Biotechnol J 2016 05 25;11(5):601-2. Epub 2016 Jan 25.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, China.

View Article
May 2016

Comparison of Transcriptional Heterogeneity of Eight Genes between Batch Desulfovibrio vulgaris Biofilm and Planktonic Culture at a Single-Cell Level.

Front Microbiol 2016 27;7:597. Epub 2016 Apr 27.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin UniversityTianjin, China; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin UniversityTianjin, China; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and EngineeringTianjin, China.

View Article
May 2016

Cyanobacterial chassis engineering for enhancing production of biofuels and chemicals.

Appl Microbiol Biotechnol 2016 Apr 17;100(8):3401-13. Epub 2016 Feb 17.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
April 2016

Biosynthesis of platform chemical 3-hydroxypropionic acid (3-HP) directly from CO2 in cyanobacterium Synechocystis sp. PCC 6803.

Metab Eng 2016 Mar 9;34:60-70. Epub 2015 Nov 9.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P.R. China; Synbio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, P.R. China. Electronic address:

View Article
March 2016

A Branch Point of Streptomyces Sulfur Amino Acid Metabolism Controls the Production of Albomycin.

Appl Environ Microbiol 2016 01 30;82(2):467-77. Epub 2015 Oct 30.

Department of Biological Sciences, Ohio University, Athens, Ohio, USA

View Article
January 2016

Premethylation of foreign DNA improves integrative transformation efficiency in Synechocystis sp. strain PCC 6803.

Appl Environ Microbiol 2015 Dec 9;81(24):8500-6. Epub 2015 Oct 9.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, Arizona, USA

View Article
December 2015

RNA-seq based transcriptomic analysis of single bacterial cells.

Integr Biol (Camb) 2015 Nov;7(11):1466-76

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P. R. China. and Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P. R. China.

View Article
November 2015

Heterologous xylose isomerase pathway and evolutionary engineering improve xylose utilization in Saccharomyces cerevisiae.

Front Microbiol 2015 21;6:1165. Epub 2015 Oct 21.

Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University Tianjin, China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), School of Chemical Engineering and Technology, Tianjin University Tianjin, China.

View Article
November 2015

Early interventional therapy for acute massive pulmonary embolism guided by minimally invasive hemodynamic monitoring.

Int J Clin Exp Med 2015 15;8(8):14011-7. Epub 2015 Aug 15.

Department of Surgery, Quzhou People's Hospital, Zhejiang University Quzhou, Zhejiang, China.

View Article
November 2015

Identification and metabolomic analysis of chemical modulators for lipid accumulation in Crypthecodinium cohnii.

Bioresour Technol 2015 Sep 18;191:362-8. Epub 2015 Mar 18.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; SynBio Platform, Collaborative Innovation Center of Chemical Science & Engineering, Tianjin, PR China. Electronic address:

View Article
September 2015

A global network-based protocol for functional inference of hypothetical proteins in Synechocystis sp. PCC 6803.

J Microbiol Methods 2015 Sep 3;116:44-52. Epub 2015 Jul 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; SynBio Platform, Collaborative Innovation Center of Chemical Science & Engineering, Tianjin, PR China. Electronic address:

View Article
September 2015

Identification of a transporter Slr0982 involved in ethanol tolerance in cyanobacterium Synechocystis sp. PCC 6803.

Front Microbiol 2015 18;6:487. Epub 2015 May 18.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University Tianjin, China ; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University Tianjin, China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin, China.

View Article
June 2015

Marchiafava-Bignami disease with rare etiology: A case report.

Exp Ther Med 2015 Apr 5;9(4):1515-1517. Epub 2015 Feb 5.

The Second Department of Neurology, Harrison International Peace Hospital, Hengshui, Hebei 053000, P.R. China.

View Article
April 2015

Metabolomic analysis reveals functional overlapping of three signal transduction proteins in regulating ethanol tolerance in cyanobacterium Synechocystis sp. PCC 6803.

Mol Biosyst 2015 Mar 11;11(3):770-82. Epub 2014 Dec 11.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P. R. China.

View Article
March 2015

Chemicals to enhance microalgal growth and accumulation of high-value bioproducts.

Front Microbiol 2015 17;6:56. Epub 2015 Feb 17.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University Tianjin, China ; Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University Tianjin, China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin, China.

View Article
March 2015

Elucidating butanol tolerance mediated by a response regulator Sll0039 in Synechocystis sp. PCC 6803 using a metabolomic approach.

Appl Microbiol Biotechnol 2015 Feb 21;99(4):1845-57. Epub 2015 Jan 21.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
February 2015

A transcriptional regulator Sll0794 regulates tolerance to biofuel ethanol in photosynthetic Synechocystis sp. PCC 6803.

Mol Cell Proteomics 2014 Dec 19;13(12):3519-32. Epub 2014 Sep 19.

From the ‡Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China; §Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P.R. China; ¶Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, P.R. China;

View Article
December 2014

Metabolomic analysis reveals mechanism of antioxidant butylated hydroxyanisole on lipid accumulation in Crypthecodinium cohnii.

J Agric Food Chem 2014 Dec 11;62(51):12477-84. Epub 2014 Dec 11.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University , Tianjin 300072, P.R. China.

View Article
December 2014

Single-cell analysis reveals gene-expression heterogeneity in syntrophic dual-culture of Desulfovibrio vulgaris with Methanosarcina barkeri.

Sci Rep 2014 Dec 15;4:7478. Epub 2014 Dec 15.

1] Laboratory of Synthetic Microbiology, School of Chemical Engineering &Technology, Tianjin University, Tianjin 300072, P.R. China [2] Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin 300072, P.R. China [3] SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), 300072, P.R. China.

View Article
December 2014

Engineering biofuel tolerance in non-native producing microorganisms.

Biotechnol Adv 2014 Mar-Apr;32(2):541-8. Epub 2014 Feb 13.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

View Article
November 2014

Metabolomic basis of laboratory evolution of butanol tolerance in photosynthetic Synechocystis sp. PCC 6803.

Microb Cell Fact 2014 Nov 1;13:151. Epub 2014 Nov 1.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, P.R. China.

View Article
November 2014

Protein Network Signatures Associated with Exogenous Biofuels Treatments in Cyanobacterium Synechocystis sp. PCC 6803.

Front Bioeng Biotechnol 2014 3;2:48. Epub 2014 Nov 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering and Technology, Tianjin University , Tianjin , China ; Key Laboratory of Systems Bioengineering, Ministry of Education of China , Tianjin , China ; SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering , Tianjin , China.

View Article
November 2014

Metabolomic and network analysis of astaxanthin-producing Haematococcus pluvialis under various stress conditions.

Bioresour Technol 2014 Oct 10;170:522-529. Epub 2014 Aug 10.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

View Article
October 2014

Bulk TiB₂-Based Ceramic Composites with Improved Mechanical Property Using Fe-Ni-Ti-Al as a Sintering Aid.

Materials (Basel) 2014 Oct 21;7(10):7105-7117. Epub 2014 Oct 21.

School of Engineering, Edith Cowan University, 270 Joondalup Drive, Joondalup, Perth, WA 6027, Australia.

View Article
October 2014

Integrated proteomic and metabolomic characterization of a novel two-component response regulator Slr1909 involved in acid tolerance in Synechocystis sp. PCC 6803.

J Proteomics 2014 Sep 3;109:76-89. Epub 2014 Jul 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

View Article
September 2014

Synthetic biology applications in industrial microbiology.

Front Microbiol 2014 26;5:451. Epub 2014 Aug 26.

Department of Chemical Engineering, School for Engineering of Matter, Transport, and Energy, Arizona State University Tempe, AZ, USA.

View Article
September 2014

An orphan two-component response regulator Slr1588 involves salt tolerance by directly regulating synthesis of compatible solutes in photosynthetic Synechocystis sp. PCC 6803.

Mol Biosyst 2014 Jul 9;10(7):1765-74. Epub 2014 Apr 9.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China.

View Article
July 2014

Single-cell analysis reveals early manifestation of cancerous phenotype in pre-malignant esophageal cells.

PLoS One 2013 8;8(10):e75365. Epub 2013 Oct 8.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America.

View Article
June 2014

Metabolomic analysis of the salt-sensitive mutants reveals changes in amino acid and fatty acid composition important to long-term salt stress in Synechocystis sp. PCC 6803.

Funct Integr Genomics 2014 Jun 19;14(2):431-40. Epub 2014 Mar 19.

Laboratory of Synthetic Microbiology, School of Chemical Engineering Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
June 2014

Butanol tolerance regulated by a two-component response regulator Slr1037 in photosynthetic Synechocystis sp. PCC 6803.

Biotechnol Biofuels 2014 11;7:89. Epub 2014 Jun 11.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China ; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, P.R. China ; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, P.R. China.

View Article
June 2014

An orphan response regulator Sll0649 involved in cadmium tolerance and metal homeostasis in photosynthetic Synechocystis sp. PCC 6803.

J Proteomics 2014 May 3;103:87-102. Epub 2014 Apr 3.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China; Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, PR China; Collaborative Innovation Center of Chemical Science and Engineering, Tianjin, PR China. Electronic address:

View Article
May 2014

Proteomic analysis reveals complex metabolic regulation in Saccharomyces cerevisiae cells against multiple inhibitors stress.

Appl Microbiol Biotechnol 2014 Mar 19;98(5):2207-21. Epub 2014 Jan 19.

Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
March 2014

Global metabolomic and network analysis of Escherichia coli responses to exogenous biofuels.

J Proteome Res 2013 Nov 24;12(11):5302-12. Epub 2013 Sep 24.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, and Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University , Tianjin 300072, P. R. China.

View Article
November 2013

Integrated metagenomic and metatranscriptomic analyses of microbial communities in the meso- and bathypelagic realm of north pacific ocean.

Mar Drugs 2013 Oct 11;11(10):3777-801. Epub 2013 Oct 11.

Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe, AZ 85287-6501, USA.

View Article
October 2013

Integrated proteomic and transcriptomic analysis reveals novel genes and regulatory mechanisms involved in salt stress responses in Synechocystis sp. PCC 6803.

Appl Microbiol Biotechnol 2013 Sep 8;97(18):8253-64. Epub 2013 Aug 8.

School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
September 2013

[Engineering photosynthetic cyanobacterial chassis: a review].

Sheng Wu Gong Cheng Xue Bao 2013 Aug;29(8):1086-99

View Article
August 2013

Integrated OMICS guided engineering of biofuel butanol-tolerance in photosynthetic Synechocystis sp. PCC 6803.

Biotechnol Biofuels 2013 Jul 25;6(1):106. Epub 2013 Jul 25.

Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P,R, China.

View Article
July 2013

Monitoring the single-cell stress response of the diatom Thalassiosira pseudonana by quantitative real-time reverse transcription-PCR.

Appl Environ Microbiol 2013 Mar 11;79(6):1850-8. Epub 2013 Jan 11.

Center for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

View Article
March 2013

Engineering cyanobacteria for photosynthetic production of 3-hydroxybutyrate directly from CO2.

Metab Eng 2013 Mar 16;16:68-77. Epub 2013 Jan 16.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University, Tempe, AZ 85287-6501, USA.

View Article
March 2013

Cross-species transcriptional network analysis reveals conservation and variation in response to metal stress in cyanobacteria.

BMC Genomics 2013 Feb 19;14:112. Epub 2013 Feb 19.

School of Chemical Engineering & Technology, Tianjin University, 300072, Tianjin, People's Republic of China.

View Article
February 2013

Systematic characterization of hypothetical proteins in Synechocystis sp. PCC 6803 reveals proteins functionally relevant to stress responses.

Gene 2013 Jan 12;512(1):6-15. Epub 2012 Oct 12.

School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China.

View Article
January 2013

Quantitative proteomics reveals dynamic responses of Synechocystis sp. PCC 6803 to next-generation biofuel butanol.

J Proteomics 2013 Jan 16;78:326-45. Epub 2012 Oct 16.

School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, PR China.

View Article
January 2013

Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor.

Mol Microbiol 2013 Jan 19;87(1):30-48. Epub 2012 Nov 19.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

View Article
January 2013

Reconstruction of distal limb defects with the free medial sural artery perforator flap.

Plast Reconstr Surg 2013 Jan;131(1):95-105

Department of Hand Surgery, Ningbo Sixth Hosspital, China.

View Article
January 2013

RNA-seq based identification and mutant validation of gene targets related to ethanol resistance in cyanobacterial Synechocystis sp. PCC 6803.

Biotechnol Biofuels 2012 Dec 21;5(1):89. Epub 2012 Dec 21.

School of Chemical Engineering & Technology, Tianjin University, Tianjin, 300072, People's Republic of China.

View Article
December 2012

Metabolomic analysis of the positive effects on Ketogulonigenium vulgare growth and 2-keto-L-gulonic acid production by reduced glutathione.

OMICS 2012 Jul-Aug;16(7-8):387-96. Epub 2012 Jun 26.

Key Laboratory of Systems Bioengineering, Ministry of Education and Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, PR China.

View Article
November 2012

Quantitative iTRAQ LC-MS/MS proteomics reveals metabolic responses to biofuel ethanol in cyanobacterial Synechocystis sp. PCC 6803.

J Proteome Res 2012 Nov 23;11(11):5286-300. Epub 2012 Oct 23.

School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China.

View Article
November 2012

Whole-genome sequence of Nocardiopsis alba strain ATCC BAA-2165, associated with honeybees.

J Bacteriol 2012 Nov;194(22):6358-9

School of Chemical Engineering & Technology, Tianjin University, Tianjin, People's Republic of China.

View Article
November 2012

Application of synthetic biology in cyanobacteria and algae.

Front Microbiol 2012 19;3:344. Epub 2012 Sep 19.

Center for Biosignatures Discovery Automation, The Biodesign Institute, Arizona State University Tempe, AZ, USA ; Biological Design Graduate Program, Arizona State University Tempe, AZ, USA.

View Article
October 2012

Proteomic analysis reveals resistance mechanism against biofuel hexane in Synechocystis sp. PCC 6803.

Biotechnol Biofuels 2012 Sep 7;5(1):68. Epub 2012 Sep 7.

School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P,R, China.

View Article
September 2012

Proteomic analysis of Ketogulonicigenium vulgare under glutathione reveals high demand for thiamin transport and antioxidant protection.

PLoS One 2012 22;7(2):e32156. Epub 2012 Feb 22.

Key Laboratory of Systems Bioengineering, Ministry of Education and Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, People's Republic of China.

View Article
August 2012

Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor.

Mol Microbiol 2012 Aug 21;85(3):535-56. Epub 2012 Jun 21.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

View Article
August 2012

Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum.

BMC Genomics 2012 Jul 30;13:349. Epub 2012 Jul 30.

Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China.

View Article
July 2012

Structure-based phylogeny of polyene macrolide antibiotic glycosyltransferases.

Gene 2012 May 8;499(2):288-96. Epub 2012 Mar 8.

School of Basic Medical Science, Tianjin Medical University, Tianjin 300070, China.

View Article
May 2012