Publications by authors named "Weiqing Kong"

16 Publications

  • Page 1 of 1

Preparation of Xylan--/P(AA--AM)/GO Nanocomposite Hydrogel and its Adsorption for Heavy Metal Ions.

Polymers (Basel) 2019 Apr 4;11(4). Epub 2019 Apr 4.

State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China.

Xylan--/P(AA--AM)/Graphene oxide (GO) hydrogels were prepared and used in the removal of heavy mental ions. Acrylamide (AM), acrylic acid (AA), and xylan were used as the raw materials to prepare the hydrogels with ammonium persulfate (APS) as the initiator. The prepared hydrogels were characterized by Fourier transform infrared (FTIR), thermogravimetric analysis (TGA), and energy dispersive X-ray (EDX). Some important properties of nanocomposite hydrogels such as swelling behavior, mechanical property, and adsorption capacity were also examined as well as the regeneration of the hydrogels. The results showed that the prepared hydrogels reached the equilibrium state of swelling after 12 h, and the compressive strength of the hydrogel with 30 mg of GO could reach up to 203 kPa. Compared with traditional hydrogel, the mechanical properties of the hydrogels with GO were obviously improved. The maximum adsorption capacity of hydrogels for Pb, Cd, and Zn could reach up to 683 mg/g, 281 mg/g, and 135 mg/g, respectively. After five cycles of adsorption and desorption, the recovery rate of the hydrogels on Pb, Cd, and Zn was still up to 87%, 80%, and 80%, respectively-all above 80%.
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http://dx.doi.org/10.3390/polym11040621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523173PMC
April 2019

Fly-through synthesis of nanoparticles on textile and paper substrates.

Nanoscale 2019 Mar;11(13):6174-6181

Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742, USA.

The fast and efficient synthesis of nanoparticles on flexible and lightweight substrates is increasingly critical for various medical and wearable applications. However, conventional high temperature (high-T) processes for nanoparticle synthesis are intrinsically incompatible with temperature-sensitive substrates, including textiles and paper (i.e. low-T substrates). In this work, we report a non-contact, 'fly-through' method to synthesize nanoparticles on low-T substrates by rapid radiative heating under short timescales. As a demonstration, textile substrates loaded with platinum (Pt) salt precursor are rapidly heated and quenched as they move across a 2000 K heating source at a continuous production speed of 0.5 cm s-1. The rapid radiative heating method induces the thermal decomposition of various precursor salts and nanoparticle formation, while the short duration ensures negligible change to the respective low-T substrate along with greatly improved production efficiency. The reported method can be generally applied to the synthesis of metal nanoparticles (e.g. gold and ruthenium) on various low-T substrates (e.g. paper). The non-contact and continuous 'fly-through' synthesis offers a robust and efficient way to synthesize supported nanoparticles on flexible and lightweight substrates. It is also promising for ultrafast and roll-to-roll manufacturing to enable viable applications.
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http://dx.doi.org/10.1039/c8nr10137jDOI Listing
March 2019

A nanofluidic ion regulation membrane with aligned cellulose nanofibers.

Sci Adv 2019 Feb 22;5(2):eaau4238. Epub 2019 Feb 22.

Department of Materials Science and Engineering, University of Maryland College Park, College Park, MD 20742, USA.

The advancement of nanofluidic applications will require the identification of materials with high-conductivity nanoscale channels that can be readily obtained at massive scale. Inspired by the transpiration in mesostructured trees, we report a nanofluidic membrane consisting of densely packed cellulose nanofibers directly derived from wood. Numerous nanochannels are produced among an expansive array of one-dimensional cellulose nanofibers. The abundant functional groups of cellulose enable facile tuning of the surface charge density via chemical modification. The nanofiber-nanofiber spacing can also be tuned from ~2 to ~20 nm by structural engineering. The surface-charge-governed ionic transport region shows a high ionic conductivity plateau of ~2 mS cm (up to 10 mM). The nanofluidic membrane also exhibits excellent mechanical flexibility, demonstrating stable performance even when the membrane is folded 150°. Combining the inherent advantages of cellulose, this novel class of membrane offers an environmentally responsible strategy for flexible and printable nanofluidic applications.
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http://dx.doi.org/10.1126/sciadv.aau4238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386557PMC
February 2019

Muscle-Inspired Highly Anisotropic, Strong, Ion-Conductive Hydrogels.

Adv Mater 2018 Sep 12;30(39):e1801934. Epub 2018 Aug 12.

Department of Materials Science and Engineering, University of Maryland, College Park, MD, 20742, USA.

Biological tissues generally exhibit excellent anisotropic mechanical properties owing to their well-developed microstructures. Inspired by the aligned structure in muscles, a highly anisotropic, strong, and conductive wood hydrogel is developed by fully utilizing the high-tensile strength of natural wood, and the flexibility and high-water content of hydrogels. The wood hydrogel exhibits a high-tensile strength of 36 MPa along the longitudinal direction due to the strong bonding and cross-linking between the aligned cellulose nanofibers (CNFs) in wood and the polyacrylamide (PAM) polymer. The wood hydrogel is 5 times and 500 times stronger than the bacterial cellulose hydrogels (7.2 MPa) and the unmodified PAM hydrogel (0.072 MPa), respectively, representing one of the strongest hydrogels ever reported. Due to the negatively charged aligned CNF, the wood hydrogel is also an excellent nanofluidic conduit with an ionic conductivity of up to 5 × 10 S cm at low concentrations for highly selective ion transport, akin to biological muscle tissue. The work offers a promising strategy to fabricate a wide variety of strong, anisotropic, flexible, and ionically conductive wood-based hydrogels for potential biomaterials and nanofluidic applications.
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http://dx.doi.org/10.1002/adma.201801934DOI Listing
September 2018

Xylan-based temperature/pH sensitive hydrogels for drug controlled release.

Carbohydr Polym 2016 Oct 24;151:189-197. Epub 2016 May 24.

Beijing Key Laboratory of Lignocellulosic Chemistry, College of Materials Science and Technology, Beijing Forestry University, Beijing, 100083, China.

Xylan-based temperature/pH sensitive hydrogels were prepared by the crosslinking copolymerization of xylan with N-isopropylacrylamide (NIPAm) and acrylic acid (AA) using N,Ń-methylenebis-acrylamide (MBA) as a cross-linker and 2,2-dimethoxy-2-phenylacetophenone as a photoinitiator via ultraviolet irradiation. The influence of the NIPAm, AA and MBA amount on properties of xylan-based hydrogels was discussed. The morphology and interactions of hydrogels were characterized by SEM and FTIR. The lower critical solution temperature (LCST) of hydrogels was investigated by DSC. The results indicated that the LCST of hydrogels emerged at around 34°C and increased with increasing the AA content. The drug encapsulation efficiency of as-prepared hydrogels reached to 97.60% and the cumulative release rate of acetylsalicylic acid was 90.12% and 26.35% in the intestinal and gastric fluid, respectively. Xylan-based hydrogels were proved to be biocompatible with NIH3T3 cell by MTT assay and showed the promising application as drug carriers for the intestinal-targeted oral drug delivery.
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http://dx.doi.org/10.1016/j.carbpol.2016.05.075DOI Listing
October 2016

Graphene Oxide/Polyacrylamide/Aluminum Ion Cross-Linked Carboxymethyl Hemicellulose Nanocomposite Hydrogels with Very Tough and Elastic Properties.

Chem Asian J 2016 06 25;11(11):1697-704. Epub 2016 May 25.

Beijing Key Laboratory of Lignocellulosic Chemistry, Beijing Forestry University, Qihuadong Road 35, Haidian District, Beijing, 100083, China.

Development of high-strength hydrogels has recently attracted ever-increasing attention. In this work, a new design strategy has been proposed to prepare graphene oxide (GO)/polyacrylamide (PAM)/aluminum ion (Al(3+) )-cross-linked carboxymethyl hemicellulose (Al-CMH) nanocomposite hydrogels with very tough and elastic properties. GO/PAM/Al-CMH hydrogels were synthesized by introducing graphene oxide (GO) into PAM/CMH hydrogel, followed by ionic cross-linking of Al(3+) . The nanocomposite hydrogels were characterized by means of FTIR, X-ray diffraction (XRD), and scanning electron microscopy/energy-dispersive X-ray analysis (SEM-EDX) along with their swelling and mechanical properties. The maximum compressive strength and the Young's modulus of GO3.5 /PAM/Al-CMH0.45 hydrogel achieved values of up to 1.12 and 13.27 MPa, increased by approximately 6488 and 18330 % relative to the PAM hydrogel (0.017 and 0.072 MPa). The as-prepared GO/PAM/Al-CMH nanocomposite hydrogels possess high strength and great elasticity giving them potential in bioengineering and drug-delivery system applications.
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http://dx.doi.org/10.1002/asia.201600138DOI Listing
June 2016

The complete chloroplast genome sequence of Morus mongolica and a comparative analysis within the Fabidae clade.

Curr Genet 2016 Feb 24;62(1):165-72. Epub 2015 Jul 24.

The Key Sericultural Laboratory of Shaanxi, Ankang University, Shaanxi, 725099, China.

The complete nucleotide sequence of the Morus mongolica chloroplast (cp) genome was reported and characterized in this study. The cp genome is a circular molecule of 158,459 bp containing a pair of 25,678 bp IR regions, separated by small and large single-copy regions of 19,736 and 87,363 bp, respectively. The number and relative positions of the 114 unique genes (80 PCGs, 30 tRNAs, and 4 rRNA genes) are almost identical to Morus indica cp genome. Further detailed comparative analyses revealed one hypervariable region, which is responsible for 88% of the total variation, and 64 indel events between two individuals. There are 78 simple sequence repeats (SSRs) in M. mongolica cp genome, in which 58 of them are mononucleotide repeats. Comparative analysis with M. indica cp genome indicated 22 SSRs with length polymorphisms and 1 SSR with nucleotide content polymorphism. The phylogenetic analysis of 60 PCGs from 62 cp genomes provided strong support for the monophyletic, single origin of Fabidae (N2-fixing) clade.
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http://dx.doi.org/10.1007/s00294-015-0507-9DOI Listing
February 2016

Homogeneous acylation of xylan with 3,5-dinitrobenzoyl in ionic liquid and the adsorption property.

Carbohydr Polym 2015 Sep 15;128:105-11. Epub 2015 Apr 15.

Biomaterials Research Center, Guangzhou Sugarcane Industry Research Institute, Guangzhou, China.

A new xylan ester (xylan 3,5-dinitrobenzoate) as a creatinine adsorbent was prepared by the homogeneous acylation of xylan with 3,5-dinitrobenzoyl chloride in 1-butul-3-methylimidazolium chloride ionic liquid. The influences of reaction conditions on the degree of substitution values of xylan esters were discussed. Results indicated that xylan esters with the degree of substitution range from 1.34 to 1.77 were obtained under the given conditions. The FTIR and (13)C NMR spectroscopies provided the evidence of grafting 3,5-dinitrobenzoyl groups onto the backbone of xylan. Moreover, the adsorption properties of the xylan ester for creatinine were also investigated. Isotherm studies showed that the sorption capacities for creatinine were 2.45, 2.08 and 1.86 mg/g for 23, 30 and 37 °C, respectively. Thermodynamic studies performed indicated the sorption process mainly was controlled by the chemical adsorption. Therefore, xylan 3,5-dinitrobenzoate displayed the promising application in the treatment of chronic renal failure by the creatinine adsorption as the new oral adsorbent.
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http://dx.doi.org/10.1016/j.carbpol.2015.04.006DOI Listing
September 2015

The complete mitochondrial genome of Rondotia menciana (Lepidoptera: Bombycidae).

J Insect Sci 2015 16;15. Epub 2015 Apr 16.

The Key Sericultural Laboratory of Shaanxi, Ankang University, Ankang, Shaanxi 725099, People's Republic of China.

The mulberry white caterpillar, Rondotia menciana Moore (Lepidoptera: Bombycidae) is a species with closest relationship with Bombyx mori and Bombyx mandarina, and the genetic information of R. menciana is important for understanding the diversity of the Bombycidae. In this study, the mitochondrial genome (mitogenome) of R. menciana was amplified by polymerase chain reaction and sequenced. The mitogenome of R. menciana was determined to be 15,301 bp, including 13 protein-coding genes (PCGs), 2 ribosomal RNA genes, 22 transfer RNA genes, and an AT-rich region. The A+T content (78.87%) was lower than that observed for other Bombycidae insects. All PCGs were initiated by ATN codons and terminated with the canonical stop codons, except for coxII, which was terminated by a single T. All the tRNA genes displayed a typical clover-leaf structure of mitochondrial tRNA. The length of AT-rich region (360 bp) of R. menciana mitogenome is shorter than that of other Bombycidae species. Phylogenetic analysis showed that the R. menciana was clustered on one branch with B. mori and B. mandarina from Bombycidae.
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http://dx.doi.org/10.1093/jisesa/iev032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535477PMC
January 2016

The complete chloroplast genome sequence of Premna microphylla Turcz.

Mitochondrial DNA A DNA Mapp Seq Anal 2016 11 28;27(6):4164-4165. Epub 2015 Jan 28.

a The Key Sericultural Laboratory of Shaanxi , Ankang University , Ankang , Shaanxi , PR China.

The complete nucleotide sequence of the Premna microphylla Turcz chloroplast (cp) genome was reported and characterized in this study. The cp genome is 155,293 bp in length, with 62.13% AT content. A pair of 25,763 bp inverted repeat regions (IR) are separated by 86,078 bp large single-copy regions (LSC) and a 17,689 bp small single-copy regions (SSC). The cp genome encodes 133 predicted functional genes, 115 are individual (80 protein-coding genes, 31 tRNA genes, four rRNA) genes, 18 are duplicated in the IR regions and ycf1 gene extends into the IR region in the junctions between IR and SSC. Of 115 individual genes, 16 genes contain one intron and two genes have two introns.
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http://dx.doi.org/10.3109/19401736.2014.1003894DOI Listing
November 2016

The complete mitochondrial genome of Diaphania pyloalis Walker (Lepidoptera: Crambidae).

Mitochondrial DNA A DNA Mapp Seq Anal 2016 11 28;27(6):4044-4045. Epub 2015 Jan 28.

a The Key Sericultural Laboratory of Shaanxi , Ankang University , Ankang , Shaanxi , PR China.

The complete mitochondrial genome (mitogenome) of Diaphania pyloalis Walker collected from China was reported and characterized. The mitogenome was 14,960 bp in length, including 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes and 1 short A + T-rich region. The A + T content of the mitochondrial genome is 80.77%. All protein-coding genes were initiated by an ATN codon, except for coxI gene which is initiated by CGA. Only coxII gene was terminated with a single T. There are 13 overlaps totaling 52 bp, and 13 intergenic spacer regions totaling 121 bp in the D. pyloalis mitogenome. The short A + T-rich region is 67 bp long, with 91.04% A + T content.
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http://dx.doi.org/10.3109/19401736.2014.1003836DOI Listing
November 2016

Posterior internal fixation plus vertebral bone implantation under navigational aid for thoracolumbar fracture treatment.

Exp Ther Med 2013 Jul 29;6(1):152-158. Epub 2013 Apr 29.

Department of Orthopaedics, The Sixth People's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai 200233, P.R. China.

The aim of this study was to investigate the method of posterior thoracolumbar vertebral pedicle screw reduction and fixation combined with vertebral bone implantation via the affected vertebral body under navigational aid for the treatment of thoracolumbar fractures. The efficacy of the procedure was also measured. Between June 2005 and March 2011, posterior thoracolumbar vertebral pedicle screw reduction and fixation plus artificial bone implantation via the affected vertebral pedicle under navigational aid was used to treat 30 patients with thoracolumbar fractures, including 18 males and 12 females, ranging in age from 21 to 57 years. Compared with the values prior to surgery, intraspinal occupation, vertebral height ratio and Cobb angle at the follow-up were significantly improved. At the long-term follow-up, the postoperative Cobb angle loss was <1° and the anterior vertebral body height loss was <2 mm. Posterior thoracolumbar vertebral pedicle screw reduction and fixation combined with vertebral bone implantation via the affected vertebral body under navigational aid may increase the accuracy and safety of surgery, and it is an ideal method of internal implantation. Bone implantation via the affected vertebral body may increase vertebral stability.
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http://dx.doi.org/10.3892/etm.2013.1087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735901PMC
July 2013

Expression of osteoprotegerin and osteoprotegerin ligand in giant cell tumor of bone and its clinical significance.

Oncol Lett 2013 Apr 19;5(4):1133-1139. Epub 2013 Feb 19.

Orthopedic Department, The General Hospital of Jinan Military Commanding Region, Jinan, Shandong 250031, P.R. China.

In this study, we used a substance P (SP) immunohistochemical method to analyze the expression localization of osteoprotegerin (OPG) and osteoprotegerin ligand (OPGL) in giant cell tumor (GCT) of the bone, and to detect the clinical significance of their expression. The data showed that the positive expression rate of OPG in the multinucleated giant cells (MGCs) and stromal cells (STCs) of GCT was 80.65 and 74.19%, respectively. The positive expression rate of OPG in MGCs was correlated with age and prognosis (P<0.05), but not in STCs. The strength of positive OPG expression in MGCs and STCs was negatively correlated with prognosis (rs=-0.397, P<0.05; rs=-0.390, P<0.05, respectively). The positive expression rate of OPGL in the MGCs and STCs was 41.94 and 67.74%, respectively. The positive expression rate of OPGL in the MGCs was correlated with age and prognosis (P<0.05); the strength of OPGL expression in MGCs was positively correlated with Campanicci's grade and recurrence. Additionally, the positive expression rate of OPGL in STCs was correlated with age and Jaffe's grade (P<0.05). The strength of OPGL expression in STCs was negatively correlated with Jaffe's grade (rs=-0.534, P<0.05). In conclusion, OPG and OPGL are expressed in MGCs and STCs in GCT of the bone. The invasion of tumor cells was positively correlated with OPGL in MGCs, which confirmed that MGCs participate in the process of osteolytic destruction of GCT of bone.
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http://dx.doi.org/10.3892/ol.2013.1199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629272PMC
April 2013

Modified posterior decompression for the management of thoracolumbar burst fractures with canal encroachment.

J Spinal Disord Tech 2010 Jul;23(5):302-9

Department of Spine Surgery, Shanghai No. 6 People's Hospital, Shanghai Jiaotong University, Shanghai, PR China.

Study Design: A retrospective study.

Objective: The purpose of this study is to explore the application of a self-designed canal decompressor in the posterior surgical treatment of thoracolumbar burst fractures with canal encroachment.

Summary Of Background Data: Surgical treatment is often indicated in the management of thoracolumbar burst fractures accompanied with canal encroachment. Efficient canal decompression would prevent progressive neurologic deterioration and facilitate recovery. Compared with anterior surgical methods, posterior approaches offer rigid fixation without formidable surgical onslaughts. However, the reduction of retropulsed bone fragments via posterior approaches is indirect and thus often inefficient.

Methods: In this study, we designed and applied a canal decompressor in the surgical treatment of 48 cases of thoracolumbar burst fractures using posterior approaches. Canal comprise, Cobb's angles, residual vertebral body height, neurologic outcome, and back pain were evaluated preoperatively and postoperatively. Patients were followed for 18 to 28 months (mean 22.5 + or - 3.5 mo) on an outpatient basis.

Results: Operations were performed within relatively short time and without significant blood loss. Radiographs indicated that applying the canal decompressor allowed efficient reduction of canal encroachment from preoperative 53.4% + or - 16.7% to postoperative 12.8 + or - 4.2%. Cobb's angles reduced from preoperative 31.0 + or - 2.5 degree to postoperative 5.1 + or - 0.6 degree. Mean vertebral height was restored to 82.5 + or - 5.7% after operations. Follow-up evaluation within 28 months indicated that neurologic recovery presented in 77.1% of patients, with average improvement of 0.86 Frankel grades. Neurologic deterioration was not observed.

Conclusions: Applying the canal decompressor enables efficient and safe reduction of bone fragments retropulsing into the canal in posterior operations. This technique thus provides an alternative method for the management of thoracolumbar burst fractures.
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http://dx.doi.org/10.1097/BSD.0b013e3181b4adcdDOI Listing
July 2010

CD133 (Prominin) negative human neural stem cells are clonogenic and tripotent.

PLoS One 2009 11;4(5):e5498. Epub 2009 May 11.

Wellcome Trust Centre for Stem Cell Research, and Department of Biochemistry, University of Cambridge, Cambridge, UK.

Background: CD133 (Prominin) is widely used as a marker for the identification and isolation of neural precursor cells from normal brain or tumor tissue. However, the assumption that CD133 is expressed constitutively in neural precursor cells has not been examined.

Methodology/principal Findings: In this study, we demonstrate that CD133 and a second marker CD15 are expressed heterogeneously in uniformly undifferentiated human neural stem (NS) cell cultures. After fractionation by flow cytometry, clonogenic tripotent cells are found in populations negative or positive for either marker. We further show that CD133 is down-regulated at the mRNA level in cells lacking CD133 immunoreactivity. Cell cycle profiling reveals that CD133 negative cells largely reside in G1/G0, while CD133 positive cells are predominantly in S, G2, or M phase. A similar pattern is apparent in mouse NS cell lines. Compared to mouse NS cells, however, human NS cell cultures harbour an increased proportion of CD133 negative cells and display a longer doubling time. This may in part reflect a sub-population of slow- or non-cycling cells amongst human NS cells because we find that around 5% of cells do not take up BrdU over a 14-day labelling period. Non-proliferating NS cells remain undifferentiated and at least some of them are capable of re-entry into the cell cycle and subsequent continuous expansion.

Conclusions: The finding that a significant fraction of clonogenic neural stem cells lack the established markers CD133 and CD15, and that some of these cells may be dormant or slow-cycling, has implications for approaches to identify and isolate neural stem cells and brain cancer stem cells. Our data also suggest the possibility that CD133 may be specifically down-regulated during G0/G1, and this should be considered when this marker is used to identify and isolate other tissue and cancer stem cells.
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005498PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676510PMC
September 2009

Radiographic evaluation of selective anterior thoracolumbar or lumbar fusion for adolescent idiopathic scoliosis.

Eur Spine J 2008 Aug 3;17(8):1012-8. Epub 2007 Oct 3.

Spine Section Department of Orthopaedics, Sixth People's Hospital affiliated to Shanghai Jiaotong University, Yishan Road 600, Shanghai, 200233, China.

According to Lenke classification of adolescent idiopathic scoliosis (AIS), patients with type 5 curve in which the structural major curve is thoracolumbar or lumbar curve with nonstructural proximal thoracic and main thoracic curves, could be surgically treated with selective anterior thoracolumbar or lumbar (TL/L) fusion. This study retrospectively analyzed the radiographies of selective anterior TL/L fusion in 35 cases of AIS with Lenke type 5 curve. Segmental fixation with a single rigid rod through anterior thoracoabdominal approach was applied in all patients. Measurements of scoliosis curve in preoperative, immediate postoperative and follow-up radiographies were analyzed. The average follow up time was 36 months (24-42 months). The average preoperative Cobb angle of the TL/L curve was 45.6 degrees and improved into 9.7 degrees immediate postoperatively, with 79.7% curve correction. In addition, the minor thoracic curve decreased from 29.7 degrees preoperatively to 17.6 degrees postoperatively, with a spontaneous correction of 41.5%. During the follow-up, a loss of 4.6 degrees correction was found and the average Cobb angle of TL/L increased to 14.4 degrees . Also, the minor thoracic curve increased to average 20.1 degrees with a loss of 2.4 degrees correction. Trunk shift deteriorated slightly immediate postoperatively and improved at the follow-up. The lowest instrumented vertebra (LIV) tilt was improved significantly and maintained its results at the follow-up. During the follow-up, the coronal disc angle immediately above the upper instrumented vertebra (UIVDA) and below the LIV (LIVDA) aggravated, while the sagittal contours of T5-T12 and T10-L2 were well maintained. The lumbar lordosis of L1-S1 and the sagittal Cobb angle of the instrumented segments were reduced slightly postoperatively and at the follow-up. There were no major complications or pseudarthrosis. The outcomes of this study show that selective anterior thoracolumbar or lumbar fusion with solid rod instrumentation is effective for surgical correction of AIS with Lenke type 5 curve. The TL/L curve, minor thoracic curve, and LIV title can be improved significantly, with good maintenance of sagittal contour. However, the UIVDA and LIVDA aggravate postoperatively when the trunk rebalances itself during follow-up. The degeneration of LIV disc warrants longer-term follow-up.
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http://dx.doi.org/10.1007/s00586-007-0510-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518755PMC
August 2008