Wei-Hua Jiao

Wei-Hua Jiao

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Wei-Hua Jiao

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Two new 5,6-epoxysterols from calcareous marine sponge .

Nat Prod Res 2019 Oct 2;33(20):2970-2976. Epub 2018 Nov 2.

b Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai , People's Republic of China.

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https://www.tandfonline.com/doi/full/10.1080/14786419.2018.1
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http://dx.doi.org/10.1080/14786419.2018.1513510DOI Listing
October 2019

Cinerols, Nitrogenous Meroterpenoids from the Marine Sponge .

J Nat Prod 2019 Sep 18;82(9):2586-2593. Epub 2019 Sep 18.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai , 200127 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.9b00471DOI Listing
September 2019

Frondoplysins A and B, Unprecedented Terpene-Alkaloid Bioconjugates from .

Org Lett 2019 Aug 27;21(16):6190-6193. Epub 2019 Jun 27.

Research Center for Marine Drugs, State Key Laboratory of Oncogene and Related Genes, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai , 200127 , China.

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http://dx.doi.org/10.1021/acs.orglett.9b01754DOI Listing
August 2019

Two new steroids with cytotoxicity from the marine sponge Dactylospongia elegans collected from the South China Sea.

Nat Prod Res 2019 May 4;33(9):1340-1344. Epub 2018 Jun 4.

a College of Pharmacy , Jinan University , Guangzhou , China.

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https://www.tandfonline.com/doi/full/10.1080/14786419.2018.1
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http://dx.doi.org/10.1080/14786419.2018.1475385DOI Listing
May 2019

Fuscasins A-D, Cycloheptapeptides from the Marine Sponge Phakellia fusca.

J Nat Prod 2019 Apr 7;82(4):970-979. Epub 2019 Mar 7.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai 200127 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.8b01033DOI Listing
April 2019

Septosones A-C, in Vivo Anti-inflammatory Meroterpenoids with Rearranged Carbon Skeletons from the Marine Sponge Dysidea septosa.

Org Lett 2019 02 24;21(3):767-770. Epub 2019 Jan 24.

Research Center for Marine Drugs, State Key Laboratory of Oncogene and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai 200127 , China.

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http://dx.doi.org/10.1021/acs.orglett.8b04019DOI Listing
February 2019

A new asymmetric diketopiperazine dimer from the sponge-associated fungus Aspergillus versicolor 16F-11.

Magn Reson Chem 2019 01 16;57(1):49-54. Epub 2018 Aug 16.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1002/mrc.4780DOI Listing
January 2019

Asperflotone, an 8(14→15)- abeo-Ergostane from the Sponge-Derived Fungus Aspergillus flocculosus 16D-1.

J Org Chem 2019 Jan 21;84(1):300-306. Epub 2018 Dec 21.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai 200127 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.joc.8b02679DOI Listing
January 2019

Divirensols: Sesquiterpene Dimers from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16.

J Nat Prod 2019 01 31;82(1):87-95. Epub 2018 Dec 31.

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience , The University of Queensland , St Lucia , QLD 4072 , Australia.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00746DOI Listing
January 2019

Aspersecosteroids A and B, Two 11(9 → 10)- abeo-5,10-Secosteroids with a Dioxatetraheterocyclic Ring System from Aspergillus flocculosus 16D-1.

Org Lett 2018 12 4;20(24):7957-7960. Epub 2018 Dec 4.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai 200127 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.orglett.8b03530DOI Listing
December 2018

(-)-Calcaridine B, a new chiral aminoimidazole-containing alkaloid from the marine sponge Leucetta chagosensis.

J Asian Nat Prod Res 2018 Nov 11:1-6. Epub 2018 Nov 11.

b Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy , Renji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200025, China.

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https://www.tandfonline.com/doi/full/10.1080/10286020.2018.1
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http://dx.doi.org/10.1080/10286020.2018.1499729DOI Listing
November 2018

Preussins with Inhibition of IL-6 Expression from Aspergillus flocculosus 16D-1, a Fungus Isolated from the Marine Sponge Phakellia fusca.

J Nat Prod 2018 10 15;81(10):2275-2281. Epub 2018 Oct 15.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai , 200127 , People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.8b00662DOI Listing
October 2018

Unusual anti-inflammatory meroterpenoids from the marine sponge Dactylospongia sp.

Org Biomol Chem 2018 09;16(36):6773-6782

College of Pharmacy, Jinan University, Guangzhou 510632, China.

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http://dx.doi.org/10.1039/c8ob01580eDOI Listing
September 2018

Popolohuanones G - I, Dimeric Sesquiterpene Quinones with IL-6 Inhibitory Activity from the Marine Sponge Dactylospongia elegans.

Chem Biodivers 2018 Jun 23;15(6):e1800078. Epub 2018 May 23.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, P. R. China.

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http://dx.doi.org/10.1002/cbdv.201800078DOI Listing
June 2018

Dysiarenone, a Dimeric C Meroterpenoid with Inhibition of COX-2 Expression from the Marine Sponge Dysidea arenaria.

Org Lett 2018 05 9;20(10):3092-3095. Epub 2018 May 9.

Research Center for Marine Drugs, State Key Laboratory of Oncogene and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine , Shanghai Jiao Tong University , Shanghai 200127 , P. R. China.

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http://dx.doi.org/10.1021/acs.orglett.8b01148DOI Listing
May 2018

Two sesquiterpene aminoquinones protect against oxidative injury in HaCaT keratinocytes via activation of AMPKα/ERK-Nrf2/ARE/HO-1 signaling.

Biomed Pharmacother 2018 Apr 22;100:417-425. Epub 2018 Feb 22.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2018.02.034DOI Listing
April 2018

Trichodermides A-E: New Peptaibols Isolated from the Australian Termite Nest-Derived Fungus Trichoderma virens CMB-TN16.

J Nat Prod 2018 04 12;81(4):976-984. Epub 2018 Mar 12.

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience , The University of Queensland , St Lucia , QLD 4072 , Australia.

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http://dx.doi.org/10.1021/acs.jnatprod.7b01072DOI Listing
April 2018

Meroterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from a Hyrtios sp. Marine Sponge.

J Nat Prod 2017 09 23;80(9):2509-2514. Epub 2017 Aug 23.

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00435DOI Listing
September 2017

Dysivillosins A-D, Unusual Anti-allergic Meroterpenoids from the Marine Sponge Dysidea villosa.

Sci Rep 2017 08 21;7(1):8947. Epub 2017 Aug 21.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China.

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http://dx.doi.org/10.1038/s41598-017-04021-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567184PMC
August 2017

Sesquiterpene Quinones/Hydroquinones from the Marine Sponge Spongia pertusa Esper.

J Nat Prod 2017 05 11;80(5):1436-1445. Epub 2017 Apr 11.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai, 200127, China.

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http://dx.doi.org/10.1021/acs.jnatprod.6b01105DOI Listing
May 2017

A microbial model of mammalian metabolism: biotransformation of 4,5-dimethoxyl-canthin-6-one using Cunninghamella blakesleeana CGMCC 3.970.

Xenobiotica 2017 Apr 30;47(4):284-289. Epub 2016 May 30.

a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University , Guangzhou , P.R. China.

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http://dx.doi.org/10.1080/00498254.2016.1184774DOI Listing
April 2017

Unusual Anti-allergic Diterpenoids from the Marine Sponge Hippospongia lachne.

Sci Rep 2017 02 22;7:43138. Epub 2017 Feb 22.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, P. R. China.

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http://dx.doi.org/10.1038/srep43138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320514PMC
February 2017

New antimalarial norterpene cyclic peroxides from Xisha Islands sponge Diacarnus megaspinorhabdosa.

Bioorg Med Chem Lett 2016 Apr 23;26(8):2084-7. Epub 2016 Feb 23.

Research Center for Marine Drugs, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.02.070DOI Listing
April 2016

New Metabolites from the South China Sea Sponge Diacarnus megaspinorhabdosa.

Chem Pharm Bull (Tokyo) 2015 ;63(6):438-42

Department of Pharmacy, Changzheng Hospital, Second Military Medical University.

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http://dx.doi.org/10.1248/cpb.c15-00022DOI Listing
February 2016

Dysiherbols A-C and Dysideanone E, Cytotoxic and NF-κB Inhibitory Tetracyclic Meroterpenes from a Dysidea sp. Marine Sponge.

J Nat Prod 2016 Feb 10;79(2):406-11. Epub 2016 Feb 10.

Research Center for Marine Drugs, Department of Pharmacy, State Key Laboratory of Oncogenes and Related Genes, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200127, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.5b01079DOI Listing
February 2016

New Furan and Cyclopentenone Derivatives from the Sponge-Associated Fungus Hypocrea Koningii PF04.

Mar Drugs 2015 Aug 26;13(9):5579-92. Epub 2015 Aug 26.

Marine Drugs Research Center, State Key Laboratory of Oncogenes and Related Genes, Department of Pharmacy, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

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http://dx.doi.org/10.3390/md13095579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584341PMC
August 2015

Cytotoxic Bryostatin Derivatives from the South China Sea Bryozoan Bugula neritina.

J Nat Prod 2015 May 1;78(5):1169-73. Epub 2015 May 1.

†Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jnatprod.5b00081DOI Listing
May 2015

(±)-Quassidines I and J, two pairs of cytotoxic bis-β-carboline alkaloid enantiomers from Picrasma quassioides.

J Nat Prod 2015 Jan 15;78(1):125-30. Epub 2014 Dec 15.

Key Laboratory for Marine Drugs, Department of Pharmacy, State Key Laboratory of Oncogenes and Related Genes, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200127, People's Republic of China.

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http://dx.doi.org/10.1021/np500801sDOI Listing
January 2015

Reniochalistatins A-E, cyclic peptides from the marine sponge Reniochalina stalagmitis.

J Nat Prod 2014 Dec 9;77(12):2678-84. Epub 2014 Dec 9.

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang 110016, People's Republic of China.

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http://pubs.acs.org/doi/10.1021/np5006778
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http://dx.doi.org/10.1021/np5006778DOI Listing
December 2014

Aaptamine derivatives with antifungal and anti-HIV-1 activities from the South China Sea sponge Aaptos aaptos.

Mar Drugs 2014 Dec 16;12(12):6003-13. Epub 2014 Dec 16.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.

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http://dx.doi.org/10.3390/md12126003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278215PMC
December 2014

Dysidinoid A, an unusual meroterpenoid with anti-MRSA activity from the South China Sea sponge Dysidea sp.

Molecules 2014 Nov 5;19(11):18025-32. Epub 2014 Nov 5.

Key Laboratory for Marine Drugs, Department of Pharmacy, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.

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http://dx.doi.org/10.3390/molecules191118025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270960PMC
November 2014

Cytotoxic aaptamine derivatives from the South China Sea sponge Aaptos aaptos.

J Nat Prod 2014 Sep 11;77(9):2124-9. Epub 2014 Sep 11.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University , 415 Fengyang Road, Shanghai 200003, People's Republic of China.

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http://dx.doi.org/10.1021/np500583zDOI Listing
September 2014

Relative and absolute stereochemistry of diacarperoxides: antimalarial norditerpene endoperoxides from marine sponge Diacarnus megaspinorhabdosa.

Mar Drugs 2014 Aug 8;12(8):4399-416. Epub 2014 Aug 8.

Key Laboratory for Marine Drugs, Department of Pharmacy, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.

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http://dx.doi.org/10.3390/md12084399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145323PMC
August 2014

New hippolide derivatives with protein tyrosine phosphatase 1B inhibitory activity from the marine sponge Hippospongia lachne.

Mar Drugs 2014 Jul 8;12(7):4096-109. Epub 2014 Jul 8.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.

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http://dx.doi.org/10.3390/md12074096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113817PMC
July 2014

Dysideanones A-C, unusual sesquiterpene quinones from the South China Sea sponge Dysidea avara.

J Nat Prod 2014 Feb 18;77(2):346-50. Epub 2014 Feb 18.

Key Laboratory for Marine Drugs, Department of Pharmacy, Renji Hospital, Shanghai Jiao Tong University School of Medicine , Shanghai 200127, People's Republic of China.

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http://dx.doi.org/10.1021/np4009392DOI Listing
February 2014

Hippolachnin A, a new antifungal polyketide from the South China Sea sponge Hippospongia lachne.

Org Lett 2013 Jul 5;15(14):3526-9. Epub 2013 Jul 5.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, PR China.

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http://dx.doi.org/10.1021/ol400933xDOI Listing
July 2013

Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata.

Bioorg Med Chem 2013 Jun 24;21(11):3290-7. Epub 2013 Mar 24.

Department of Pharmacy, Renji Hospital, Affiliated to School of Medicine, Shanghai Jiaotong University, Dongfang Road 1630, Shanghai 200127, People's Republic of China.

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http://dx.doi.org/10.1016/j.bmc.2013.03.018DOI Listing
June 2013

Formamido-diterpenes from the South China Sea sponge Acanthella cavernosa.

Mar Drugs 2012 Jul 2;10(7):1445-58. Epub 2012 Jul 2.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.

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http://www.mdpi.com/1660-3397/10/7/1445
Publisher Site
http://dx.doi.org/10.3390/md10071445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407923PMC
July 2012

Simplexolides A-E and plakorfuran A, six butyrate derived polyketides from the marine sponge .

Tetrahedron 2012 Jun 14;68(24):4635-4640. Epub 2012 Apr 14.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, People's Republic of China.

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http://dx.doi.org/10.1016/j.tet.2012.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114024PMC
June 2012

Woodylides A-C, new cytotoxic linear polyketides from the South China Sea sponge Plakortis simplex.

Mar Drugs 2012 May 7;10(5):1027-36. Epub 2012 May 7.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.

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http://dx.doi.org/10.3390/md10051027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397464PMC
May 2012

Kidney transplantation in diabetic recipients with iliac atherosclerosis: arterial anastomosis with Nakayama's ring pin stapler after endarterectomy.

Int J Urol 2012 Apr 14;19(4):336-42. Epub 2011 Dec 14.

Department of Organ Transplantation, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

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http://dx.doi.org/10.1111/j.1442-2042.2011.02934.xDOI Listing
April 2012

Dysidavarones A-D, new sesquiterpene quinones from the marine sponge Dysidea avara.

Org Lett 2012 Jan 1;14(1):202-5. Epub 2011 Dec 1.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, PR China.

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http://pubs.acs.org/doi/10.1021/ol202994c
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http://dx.doi.org/10.1021/ol202994cDOI Listing
January 2012

Anti-inflammatory alkaloids from the stems of Picrasma quassioides BENNET.

Chem Pharm Bull (Tokyo) 2011 ;59(3):359-64

School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

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http://dx.doi.org/10.1248/cpb.59.359DOI Listing
June 2011

Simplextones A and B, unusual polyketides from the marine sponge Plakortis simplex.

Org Lett 2011 Jun 23;13(12):3154-7. Epub 2011 May 23.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, People's Republic of China.

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http://dx.doi.org/10.1021/ol201055wDOI Listing
June 2011

A new neolignan and a new sesterterpenoid from the stems of Picrasma quassioides Bennet.

Chem Biodivers 2011 Jun;8(6):1163-9

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China.

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http://dx.doi.org/10.1002/cbdv.201000137DOI Listing
June 2011

Hippolides A-H, acyclic manoalide derivatives from the marine sponge Hippospongia lachne.

J Nat Prod 2011 May 6;74(5):1248-54. Epub 2011 May 6.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, People's Republic of China.

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http://dx.doi.org/10.1021/np200227sDOI Listing
May 2011

Anti-inflammatory triterpenes from the leaves of Rosa laevigata.

J Nat Prod 2011 Apr 8;74(4):732-8. Epub 2011 Mar 8.

Laboratory of Marine Drugs, Department of Pharmacy, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai 200003, People's Republic of China.

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http://dx.doi.org/10.1021/np1007922DOI Listing
April 2011

New isocourmarin and phthalide derivatives from the rhizomes of Matteuccia orientalis.

Chem Pharm Bull (Tokyo) 2010 Dec;58(12):1650-4

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.

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http://dx.doi.org/10.1248/cpb.58.1650DOI Listing
December 2010

Beta-carboline alkaloids from the stems of Picrasma quassioides.

Magn Reson Chem 2010 Jun;48(6):490-5

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, PR China.

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http://dx.doi.org/10.1002/mrc.2602DOI Listing
June 2010

Quassidines A-D, bis-beta-carboline alkaloids from the stems of Picrasma quassioides.

J Nat Prod 2010 Feb;73(2):167-71

College of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, People's Republic of China.

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http://dx.doi.org/10.1021/np900538rDOI Listing
February 2010