Wataru Nakajima

Wataru Nakajima

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Wataru Nakajima

Wataru Nakajima

Publications by authors named "Wataru Nakajima"

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14Publications

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p53-independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells.

Mol Oncol 2018 06 17;12(6):788-798. Epub 2018 Apr 17.

Philips Institute for Oral Health Research, School of Dentistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, USA.

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http://doi.wiley.com/10.1002/1878-0261.12172
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http://dx.doi.org/10.1002/1878-0261.12172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983129PMC
June 2018

Chaperone-mediated autophagy promotes lung cancer cell survival through selective stabilization of the pro-survival protein, MCL1.

Biochem Biophys Res Commun 2017 Jan 7;482(4):1334-1340. Epub 2016 Dec 7.

Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.12.037DOI Listing
January 2017

Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer.

Cancer Biol Ther 2016 ;17(1):27-35

a Department of Oral and Craniofacial Molecular Biology , School of Dentistry, Massey Cancer Center, Virginia Commonwealth University , Richmond , Virginia , USA.

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http://dx.doi.org/10.1080/15384047.2015.1108485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847809PMC
October 2016

DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex.

Oncotarget 2016 Jun;7(24):36353-36365

Phillips Institute for Oral Health Research, School of Dentistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.18632/oncotarget.9217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5095005PMC
June 2016

Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.

Biochem Biophys Res Commun 2016 Apr 18;473(2):490-6. Epub 2016 Mar 18.

Department of Molecular Oncology, Institute for Advanced Medical Sciences, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.03.053DOI Listing
April 2016

Yet another function of p53--the switch that determines whether radiation-induced autophagy will be cytoprotective or nonprotective: implications for autophagy inhibition as a therapeutic strategy.

Mol Pharmacol 2015 May 9;87(5):803-14. Epub 2015 Feb 9.

Departments of Medicine and Pharmacology and Toxicology, Massey Cancer Center (S.C., K.S., A.A., D.B., N.L., D.A.G.), and Department of Oral and Craniofacial Molecular Biology, School of Dentistry (H.H., W.N., W.A.Y.), Virginia Commonwealth University, Richmond, Virginia; and Departments of Molecular Biology and Biophysics (S.V.T.) and Medicine (F.M.T.), University of Connecticut Health Sciences, Farmington, Connecticut

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http://dx.doi.org/10.1124/mol.114.095273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407732PMC
May 2015

p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.

J Cell Biol 2014 Mar 24;204(7):1191-207. Epub 2014 Mar 24.

Mechanobiology Institute, Level 10, T-Lab, National University of Singapore, Singapore 117411, Singapore.

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http://dx.doi.org/10.1083/jcb.201309107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971739PMC
March 2014

Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.

PLoS One 2013 5;8(4):e60685. Epub 2013 Apr 5.

Department of Oral and Craniofacial Molecular Biology, School of Dentistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060685PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618047PMC
October 2013

Noxa induces apoptosis in oncogene-expressing cells through catch-and-release mechanism operating between Puma and Mcl-1.

Biochem Biophys Res Commun 2011 Oct 14;413(4):643-8. Epub 2011 Sep 14.

Department of Molecular Oncology, Institute of Gerontology, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki 211-8533, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.09.036DOI Listing
October 2011

5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis.

Cancer Invest 2008 Aug;26(7):680-8

Department of Molecular Oncology, Institute of Gerontology, Nippon Medical School, Kanagawa, Japan.

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http://dx.doi.org/10.1080/07357900701840212DOI Listing
August 2008

Synergistic induction of apoptosis by p53-inducible Bcl-2 family proteins Noxa and Puma.

J Nippon Med Sch 2007 Apr;74(2):148-57

Department of Molecular Oncology, Institute of Gerontology, Graduate School of Medicine, Nippon Medical School, 1-396 Kosugi-cho, Nakahara-ku, Kawasaki, Kanagawa 211-8533, Japan.

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http://dx.doi.org/10.1272/jnms.74.148DOI Listing
April 2007