Wassim Abou-Kheir

Wassim Abou-Kheir

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Wassim Abou-Kheir

Wassim Abou-Kheir

Publications by authors named "Wassim Abou-Kheir"

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40Publications

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The synthetic retinoid ST1926 attenuates prostate cancer growth and potentially targets prostate cancer stem-like cells.

Mol Carcinog 2019 Jul 18;58(7):1208-1220. Epub 2019 Mar 18.

Department of Anatomy, Cell Biology, and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.1002/mc.23004DOI Listing
July 2019

Tet Is Expressed in Midline Glia and Is Required for Proper Axonal Development.

Front Cell Neurosci 2019 4;13:252. Epub 2019 Jun 4.

Department of Experimental Pathology and Immunology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.3389/fncel.2019.00252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558204PMC
June 2019

Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier.

Front Mol Neurosci 2019 27;12:131. Epub 2019 May 27.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.3389/fnmol.2019.00131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546065PMC
May 2019

Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From -Deficient Murine Lung Adenocarcinoma With Somatic Mutations.

Front Oncol 2019 2;9:207. Epub 2019 Apr 2.

Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.3389/fonc.2019.00207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454871PMC
April 2019

Assessing Radiosensitivity of Bladder Cancer : A 2D vs. 3D Approach.

Front Oncol 2019 19;9:153. Epub 2019 Mar 19.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.3389/fonc.2019.00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433750PMC
March 2019

The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma.

Oncotarget 2018 Sep 11;9(71):33549-33561. Epub 2018 Sep 11.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://www.oncotarget.com/fulltext/26088
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http://dx.doi.org/10.18632/oncotarget.26088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173359PMC
September 2018

Androgen deprivation therapy-induced epithelial-mesenchymal transition of prostate cancer through downregulating SPDEF and activating CCL2.

Biochim Biophys Acta Mol Basis Dis 2018 May 21;1864(5 Pt A):1717-1727. Epub 2018 Mar 21.

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2018.02.016DOI Listing
May 2018

Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus.

Front Cell Neurosci 2018 17;12:135. Epub 2018 May 17.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.3389/fncel.2018.00135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967150PMC
May 2018

Docosahexaenoic acid (DHA) enhances the therapeutic potential of neonatal neural stem cell transplantation post-Traumatic brain injury.

Behav Brain Res 2018 03 7;340:1-13. Epub 2017 Nov 7.

Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut, Beirut, Lebanon, Lebanon; Department of Psychiatry, Center for Neuroproteomics and Biomarkers Research, University of Florida, Gainesville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.11.007DOI Listing
March 2018

Ki-67 expression predicts biochemical recurrence after radical prostatectomy in the setting of positive surgical margins.

BMC Urol 2018 Mar 5;18(1):13. Epub 2018 Mar 5.

Division of Urology, Faculty of Medicine, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El-Solh, Beirut, 1107 2020, Lebanon.

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http://dx.doi.org/10.1186/s12894-018-0330-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838874PMC
March 2018

Intracerebroventricular injections of endotoxin (ET) reduces hippocampal neurogenesis.

J Neuroimmunol 2018 Feb 18;315:58-67. Epub 2017 Dec 18.

Dept. of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Lebanon. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2017.12.013DOI Listing
February 2018

Disruption of ETV6 leads to TWIST1-dependent progression and resistance to epidermal growth factor receptor tyrosine kinase inhibitors in prostate cancer.

Mol Cancer 2018 02 19;17(1):42. Epub 2018 Feb 19.

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, 250 Wu-Hsing Street, Taipei, 11031, Taiwan.

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http://dx.doi.org/10.1186/s12943-018-0785-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817720PMC
February 2018

Prostate Cancer and Aspirin Use: Synopsis of the Proposed Molecular Mechanisms.

Front Pharmacol 2017 21;8:145. Epub 2017 Mar 21.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut Beirut, Lebanon.

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http://dx.doi.org/10.3389/fphar.2017.00145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5359278PMC
March 2017

HTR-8/SVneo cell line contains a mixed population of cells.

Placenta 2017 02 7;50:1-7. Epub 2016 Dec 7.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2016.12.007DOI Listing
February 2017

Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma.

Front Mol Neurosci 2017 28;10:50. Epub 2017 Feb 28.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut Beirut, Lebanon.

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http://dx.doi.org/10.3389/fnmol.2017.00050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329035PMC
February 2017

Chemosensitivity of U251 Cells to the Co-treatment of D-Penicillamine and Copper: Possible Implications on Wilson Disease Patients.

Front Mol Neurosci 2017 31;10:10. Epub 2017 Jan 31.

Department of Biochemistry and Molecular Genetics, Faculty of Medicine, American University of Beirut Beirut, Lebanon.

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http://dx.doi.org/10.3389/fnmol.2017.00010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281637PMC
January 2017

Thalamic Stimulation in Awake Rats Induces Neurogenesis in the Hippocampal Formation.

Brain Stimul 2016 Jan-Feb;9(1):101-8. Epub 2015 Sep 15.

Department of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

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http://dx.doi.org/10.1016/j.brs.2015.09.006DOI Listing
September 2016

A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells.

PLoS One 2015 2;10(10):e0139939. Epub 2015 Oct 2.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139939PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592186PMC
June 2016

Primary versus castration-resistant prostate cancer: modeling through novel murine prostate cancer cell lines.

Oncotarget 2016 May;7(20):28961-75

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://dx.doi.org/10.18632/oncotarget.8436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045370PMC
May 2016

Berberis libanotica Ehrenb extract shows anti-neoplastic effects on prostate cancer stem/progenitor cells.

PLoS One 2014 7;9(11):e112453. Epub 2014 Nov 7.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112453PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224486PMC
January 2016

Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells.

Front Neurosci 2015 23;9:442. Epub 2015 Nov 23.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut Beirut, Lebanon.

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http://dx.doi.org/10.3389/fnins.2015.00442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655242PMC
December 2015

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer.

Oncotarget 2015 Jan;6(1):441-57

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381606PMC
http://dx.doi.org/10.18632/oncotarget.2690DOI Listing
January 2015

Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene.

J Cancer 2014 9;5(9):736-44. Epub 2014 Oct 9.

2. Department of Anatomy, Cell Biology and Physiology, Faculty of Medicine, American University of Beirut, Beirut - Lebanon and.

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http://dx.doi.org/10.7150/jca.9726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216797PMC
November 2014

Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance.

Oncotarget 2014 Jun;5(11):3770-84

Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan; Center of Excellence for Cancer Research, Wan Fang Hospital, College of Medicine, Taipei Medical University, Taipei, Taiwan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116519PMC
http://dx.doi.org/10.18632/oncotarget.1994DOI Listing
June 2014

TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation.

PLoS One 2012 30;7(7):e41668. Epub 2012 Jul 30.

Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041668PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408501PMC
April 2013

Self-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity.

PLoS One 2011 11;6(10):e26112. Epub 2011 Oct 11.

Cell and Cancer Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026112PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191168PMC
February 2012

Prostate epithelial Pten/TP53 loss leads to transformation of multipotential progenitors and epithelial to mesenchymal transition.

Am J Pathol 2011 Jul 13;179(1):422-35. Epub 2011 May 13.

Cell and Cancer Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.03.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123810PMC
July 2011

Characterizing the contribution of stem/progenitor cells to tumorigenesis in the Pten-/-TP53-/- prostate cancer model.

Stem Cells 2010 Dec;28(12):2129-40

Cell and Cancer Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/stem.538DOI Listing
December 2010

Regulation of podosome dynamics by WASp phosphorylation: implication in matrix degradation and chemotaxis in macrophages.

J Cell Sci 2009 Nov 6;122(Pt 21):3873-82. Epub 2009 Oct 6.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1242/jcs.051755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773189PMC
November 2009

Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.

J Cell Sci 2008 Feb 15;121(Pt 3):379-90. Epub 2008 Jan 15.

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1242/jcs.010272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2749557PMC
February 2008

A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages.

J Cell Sci 2005 Nov;118(Pt 22):5369-79

Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, New York City, NY 10461, USA.

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http://dx.doi.org/10.1242/jcs.02638DOI Listing
November 2005

Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes.

Anticancer Drugs 2004 Apr;15(4):389-99

Department of Biology, American University of Beirut, Beirut, Lebanon.

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April 2004