Wan L Lam

Wan L Lam

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Wan L Lam

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Beyond sequence homology: Cellular biology limits the potential of XIST to act as a miRNA sponge.

PLoS One 2019 16;14(8):e0221371. Epub 2019 Aug 16.

Department of Integrative Oncology, BC Cancer Research Centre, Vancouver, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221371PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697314PMC
August 2019

Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis.

J Thorac Oncol 2019 Apr 19;14(4):656-671. Epub 2018 Dec 19.

Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440869PMC
April 2019

Expanding the miRNA Transcriptome of Human Kidney and Renal Cell Carcinoma.

Int J Genomics 2018 3;2018:6972397. Epub 2018 Jul 3.

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1155/2018/6972397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051088PMC
July 2018

Genomics and Epigenetics of Malignant Mesothelioma.

High Throughput 2018 Jul 27;7(3). Epub 2018 Jul 27.

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, BC V5Z 1L3, Canada.

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http://dx.doi.org/10.3390/ht7030020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163664PMC
July 2018

Environmental arsenic exposure: From genetic susceptibility to pathogenesis.

Environ Int 2018 03 22;112:183-197. Epub 2017 Dec 22.

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2017.12.017DOI Listing
March 2018

cGAS-STING and Cancer: Dichotomous Roles in Tumor Immunity and Development.

Trends Immunol 2018 01 19;39(1):44-54. Epub 2017 Aug 19.

Department of Integrative Oncology, BC Cancer Agency, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.it.2017.07.013DOI Listing
January 2018

Non-coding RNAs predict recurrence-free survival of patients with hypoxic tumours.

Sci Rep 2018 01 9;8(1):152. Epub 2018 Jan 9.

Department of Integrative Oncology, British Columbia Cancer Agency, Vancouver, B.C, V5Z 1L3, Canada.

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http://dx.doi.org/10.1038/s41598-017-18462-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760628PMC
January 2018

Small non-coding RNA transcriptome of the NCI-60 cell line panel.

Sci Data 2017 10 24;4:170157. Epub 2017 Oct 24.

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada V5Z 1L3.

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http://dx.doi.org/10.1038/sdata.2017.157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654365PMC
October 2017

DLK1-DIO3 imprinted locus deregulation in development, respiratory disease, and cancer.

Expert Rev Respir Med 2017 09 20;11(9):749-761. Epub 2017 Jul 20.

a British Columbia Cancer Research Centre , Vancouver , BC , Canada.

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http://dx.doi.org/10.1080/17476348.2017.1355241DOI Listing
September 2017

Nuclear Factor I/B: A Master Regulator of Cell Differentiation with Paradoxical Roles in Cancer.

EBioMedicine 2017 Aug 27;22:2-9. Epub 2017 May 27.

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada; Interdisciplinary Oncology Program, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.ebiom.2017.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552107PMC
August 2017

Oncogenomic disruptions in arsenic-induced carcinogenesis.

Oncotarget 2017 Apr;8(15):25736-25755

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.18632/oncotarget.15106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421966PMC
April 2017

MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis.

Neoplasia 2017 04 16;19(4):321-332. Epub 2017 Mar 16.

James Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202; Department of Medicine, Division of Hematology and Oncology, University of Louisville School of Medicine, Louisville, KY 40202; Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2017.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361868PMC
April 2017

Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome.

Oncotarget 2016 Dec;7(49):80957-80966

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, B.C. V5Z 1L3, Canada.

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http://dx.doi.org/10.18632/oncotarget.13133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348368PMC
December 2016

An atlas of gastric PIWI-interacting RNA transcriptomes and their utility for identifying signatures of gastric cancer recurrence.

Gastric Cancer 2016 Apr 17;19(2):660-665. Epub 2015 Mar 17.

Department of Integrative Oncology, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, Canada.

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http://dx.doi.org/10.1007/s10120-015-0487-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573768PMC
April 2016

Assessment of the clinical relevance of 17q25.3 copy number and three-dimensional telomere organization in non-small lung cancer patients.

J Cancer Res Clin Oncol 2016 Apr 30;142(4):749-56. Epub 2015 Nov 30.

Genomic Centre for Cancer Research and Diagnosis, Manitoba Institute of Cell Biology, University of Manitoba, 675 McDermot Avenue, Room ON6045, Winnipeg, MB, Canada.

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http://dx.doi.org/10.1007/s00432-015-2080-5DOI Listing
April 2016

Identification of the epigenetic reader CBX2 as a potential drug target in advanced prostate cancer.

Clin Epigenetics 2016 12;8:16. Epub 2016 Feb 12.

Department of Experimental Therapeutics, British Columbia Cancer Research Centre, 675 W 10th Avenue, Vancouver, British Columbia V5Z 1L3 Canada ; Department of Surgery, University of British Columbia, 910 W 10th Avenue, Vancouver, British Columbia V5Z 4E3 Canada.

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http://dx.doi.org/10.1186/s13148-016-0182-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751702PMC
April 2016

Macrophages, Inflammation, and Lung Cancer.

Am J Respir Crit Care Med 2016 Jan;193(2):116-30

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1164/rccm.201508-1545CIDOI Listing
January 2016

Disruption of KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex components by multiple genetic mechanisms: Association with poor prognosis in head and neck cancer.

Head Neck 2015 May 18;37(5):727-34. Epub 2014 Jun 18.

Department of Integrative Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://doi.wiley.com/10.1002/hed.23663
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http://dx.doi.org/10.1002/hed.23663DOI Listing
May 2015

Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.

Biomed Res Int 2014 9;2014:159459. Epub 2014 Jul 9.

BC Cancer Research Centre, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3.

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http://dx.doi.org/10.1155/2014/159459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121105PMC
April 2015

Polycomb-mediated silencing in neuroendocrine prostate cancer.

Clin Epigenetics 2015 3;7:40. Epub 2015 Apr 3.

Department of Experimental Therapeutics, British Columbia Cancer Research Centre, 675 W 10th Avenue, Vancouver, BC V5Z 1 L3 Canada ; Interdisciplinary Oncology Program, Faculty of Medicine, University of British Columbia, 675 W 10th Avenue, Vancouver, BC V5Z 1 L3 Canada ; Department of Surgery, University of British Columbia, 910 W 10th Avenue, Vancouver, BC V5Z 4E3 Canada.

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http://dx.doi.org/10.1186/s13148-015-0074-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391120PMC
April 2015

Loss of the Notch effector RBPJ promotes tumorigenesis.

J Exp Med 2015 Jan 15;212(1):37-52. Epub 2014 Dec 15.

Genome Sciences Centre, Integrative Oncology Department, and Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada Genome Sciences Centre, Integrative Oncology Department, and Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada Experimental Medicine Program and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver V6T 2B5, British Columbia, Canada Experimental Medicine Program and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver V6T 2B5, British Columbia, Canada

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http://www.imls.uzh.ch/static/CMS_publications/robinson/lite
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http://www.jem.org/lookup/doi/10.1084/jem.20121192
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http://dx.doi.org/10.1084/jem.20121192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291530PMC
January 2015

SOX15 and other SOX family members are important mediators of tumorigenesis in multiple cancer types.

Oncoscience 2014 2;1(5):326-35. Epub 2014 Jun 2.

Ontario Cancer Institute, Princess Margaret Hospital, University Health Network at the University of Toronto.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278306PMC
http://dx.doi.org/10.18632/oncoscience.46DOI Listing
January 2015

Targeting of chemoprevention to high-risk potentially malignant oral lesions: challenges and opportunities.

Oral Oncol 2014 Dec 16;50(12):1123-30. Epub 2014 Sep 16.

BC Cancer Research Centre, Department of Cancer Control Research, Vancouver, Canada; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2014.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539364PMC
December 2014

NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer.

Oncotarget 2014 Nov;5(22):11081-90

Departments of Radiation Oncology, Medical Biophysics, Medical Oncology, Laboratory Medicine and Pathology, Pharmacology & Toxicology and Biostatistics, Computer Science, University of Toronto, Toronto, ON, Canada. Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.

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http://www.oncotarget.com/fulltext/2404
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294365PMC
http://dx.doi.org/10.18632/oncotarget.2404DOI Listing
November 2014

Smoking status impacts microRNA mediated prognosis and lung adenocarcinoma biology.

BMC Cancer 2014 Oct 24;14:778. Epub 2014 Oct 24.

Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia V5Z 1L3, Canada.

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http://dx.doi.org/10.1186/1471-2407-14-778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4216369PMC
October 2014

Re: the Wnt signaling pathway in non-small cell lung cancer.

J Natl Cancer Inst 2014 Aug 31;106(8). Epub 2014 Jul 31.

: Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada (RH, KLT, WLL).

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http://dx.doi.org/10.1093/jnci/dju188DOI Listing
August 2014

YEATS4 is a novel oncogene amplified in non-small cell lung cancer that regulates the p53 pathway.

Cancer Res 2013 Dec 29;73(24):7301-12. Epub 2013 Oct 29.

Authors' Affiliations: Integrative Oncology, BC Cancer Research Center, Vancouver, BC, Canada; National Institutes of Health, Bethesda, Maryland; Department of Genetics, Harvard Medical School, Boston, Massachusetts; and Hamon Center of Therapeutics, University of Texas South Western, Dallas, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959870PMC
December 2013

Genetic alterations defining NSCLC subtypes and their therapeutic implications.

Lung Cancer 2013 Nov 20;82(2):179-89. Epub 2013 Aug 20.

British Columbia Cancer Research Centre, Vancouver, BC, V5Z 1L3, Canada; Department of Integrative Oncology, BC Cancer Research Center, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2013.07.025DOI Listing
November 2013

CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer.

J Thorac Oncol 2013 Nov;8(11):1378-88

*Hamon Center for Therapeutic Oncology Research and †Division of Biostatistics, University of Texas Southwestern Medical Center, Dallas, Texas; ‡Department of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver, B.C., Canada; §Texas Scottish Rite Hospital for Children, Dallas, Texas; ‖Department of Surgery, Biochemistry, and Molecular Biology, Keck School of Medicine, USC/Norris Comprehensive Cancer Center, Los Angeles, California; ¶Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington; #Oncology Biomarker Development, Genentech Inc., South San Francisco, California; **Department of Molecular and Cell Biology, Center for Systems Biology, University of Texas at Dallas, Dallas, Texas; and ††Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1097/JTO.0b013e3182a46c0cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951422PMC
November 2013

Whole-genome sequencing analysis identifies a distinctive mutational spectrum in an arsenic-related lung tumor.

J Thorac Oncol 2013 Nov;8(11):1451-5

*Department of Integrative Oncology, BC Cancer Agency, Vancouver, Canada; and †Program of Cell and Molecular Biology, Faculty of Medicine, University of Chile, Santiago, Chile.

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http://dx.doi.org/10.1097/JTO.0b013e3182a4dd8eDOI Listing
November 2013

In response.

J Thorac Oncol 2013 Nov;8(11):e103-4

British Columbia Cancer Research Centre Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/01.JTO.0000435739.64803.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925784PMC
November 2013

Emerging arsenic threat in Canada.

Science 2013 Nov;342(6158):559

British Columbia Cancer Agency, Vancouver, BC V5Z1L3, Canada.

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http://www.sciencemag.org/cgi/doi/10.1126/science.342.6158.5
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http://dx.doi.org/10.1126/science.342.6158.559-aDOI Listing
November 2013

Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.

Mol Cancer 2013 Oct 20;12(1):124. Epub 2013 Oct 20.

BC Cancer Research Centre, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z1L3, Canada.

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http://dx.doi.org/10.1186/1476-4598-12-124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016213PMC
October 2013

EZH2 promotes E2F-driven SCLC tumorigenesis through modulation of apoptosis and cell-cycle regulation.

J Thorac Oncol 2013 Aug;8(8):1102-6

Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/JTO.0b013e318298762fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713495PMC
August 2013

Applications of array-CGH for lung cancer.

Methods Mol Biol 2013 ;973:297-324

Department of Pathology, Toronto General Hospital University Health Network, Toronto, ON, Canada.

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http://link.springer.com/10.1007/978-1-62703-281-0_19
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http://dx.doi.org/10.1007/978-1-62703-281-0_19DOI Listing
July 2013

Molecular features in arsenic-induced lung tumors.

Mol Cancer 2013 Mar 19;12:20. Epub 2013 Mar 19.

British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada.

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http://dx.doi.org/10.1186/1476-4598-12-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626870PMC
March 2013

Elevated expression of BIRC6 protein in non-small-cell lung cancers is associated with cancer recurrence and chemoresistance.

J Thorac Oncol 2013 Feb;8(2):161-70

Department of Experimental Therapeutics, BC Cancer Agency, Cancer Research Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/JTO.0b013e31827d5237DOI Listing
February 2013

Aberrant expression of long noncoding RNAs in cervical intraepithelial neoplasia.

Int J Gynecol Cancer 2012 Nov;22(9):1557-63

British Columbia Cancer Agency Research Centre, 675 West 10th Ave, Vancouver, BC, Canada.

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https://insights.ovid.com/crossref?an=00009577-201211000-000
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http://dx.doi.org/10.1097/IGC.0b013e318272f2c9DOI Listing
November 2012

Arsenic, asbestos and radon: emerging players in lung tumorigenesis.

Environ Health 2012 Nov 22;11:89. Epub 2012 Nov 22.

British Columbia Cancer Research Centre, Vancouver, BC, V5Z 1L3, Canada.

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http://ehjournal.biomedcentral.com/articles/10.1186/1476-069
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http://dx.doi.org/10.1186/1476-069X-11-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534001PMC
November 2012

Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate-risk prostate cancer.

Prostate 2012 Sep 27;72(12):1295-305. Epub 2011 Dec 27.

Department of Radiation Oncology, Medical Biophysics, Laboratory Medicine and Pathology, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/pros.22478
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http://dx.doi.org/10.1002/pros.22478DOI Listing
September 2012

Arsenic exposure and the induction of human cancers.

J Toxicol 2011 15;2011:431287. Epub 2011 Nov 15.

Department of Integrative Oncology, British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3.

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http://dx.doi.org/10.1155/2011/431287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235889PMC
August 2012

Induction of human squamous cell-type carcinomas by arsenic.

J Skin Cancer 2011 6;2011:454157. Epub 2011 Dec 6.

Department of Integrative Oncology, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3.

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http://dx.doi.org/10.1155/2011/454157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235812PMC
August 2012

Mechanistic Roles of Noncoding RNAs in Lung Cancer Biology and Their Clinical Implications.

Genet Res Int 2012 18;2012:737416. Epub 2012 Jul 18.

British Columbia Cancer Research Center, Vancouver, BC, Canada V5Z 1L3.

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http://dx.doi.org/10.1155/2012/737416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407615PMC
August 2012

Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.

Genome Res 2012 Jul 21;22(7):1197-211. Epub 2012 May 21.

Department of Surgery, Department of Biochemistry and Molecular Biology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089-9176, USA.

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http://dx.doi.org/10.1101/gr.132662.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396362PMC
July 2012

Potential application of non-small cell lung cancer-associated autoantibodies to early cancer diagnosis.

Biochem Biophys Res Commun 2012 Jul 16;423(3):613-9. Epub 2012 Jun 16.

Tianjin Lung Cancer Institute, Tianjin General Hospital, Tianjin Medical University, Tianjin 300070, China.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1201138
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http://dx.doi.org/10.1016/j.bbrc.2012.06.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512951PMC
July 2012

Arsenic and lung cancer in never-smokers: lessons from Chile.

Am J Respir Crit Care Med 2012 May;185(10):1131-2

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http://dx.doi.org/10.1164/ajrccm.185.10.1131DOI Listing
May 2012

Integrative genomics identified RFC3 as an amplified candidate oncogene in esophageal adenocarcinoma.

Clin Cancer Res 2012 Apr 10;18(7):1936-46. Epub 2012 Feb 10.

Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-1431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523177PMC
April 2012

Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma.

Proc Natl Acad Sci U S A 2012 Mar 28;109(11):4251-6. Epub 2012 Feb 28.

Department of Surgery, Department of Pathology, and Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.1011989109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306720PMC
March 2012

MicroRNAs As Biomarkers For Clinical Features Of Lung Cancer.

Metabolomics (Los Angel) 2012 Mar;2(3):1000108

Department of Integrative Oncology, British Columbia Cancer Research Centre, 675 West 10th Avenue, V5Z 1L3 Vancouver, B.C., Canada.

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https://www.omicsonline.org/micrornas-as-biomarkers-for-clin
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http://dx.doi.org/10.4172/2153-0769.1000108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159950PMC
March 2012

T cells of patients with myelodysplastic syndrome are frequently derived from the malignant clone.

Br J Haematol 2012 Feb;156(3):409-12

Pathology and Laboratory Medicine of British Columbia Children's Hospital; Bristish Columbia Genome Sciences Centre, BC Cancer Agency; Pathology and Laboratory Medicine, University of British Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191868PMC
http://dx.doi.org/10.1111/j.1365-2141.2011.08872.xDOI Listing
February 2012

Translating cancer 'omics' to improved outcomes.

Genome Res 2012 Feb;22(2):188-95

British Columbia Cancer Research Centre, Vancouver V5Z 1L3, Canada.

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http://dx.doi.org/10.1101/gr.124354.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266027PMC
February 2012

Long non-coding RNAs are expressed in oral mucosa and altered in oral premalignant lesions.

Oral Oncol 2011 Nov 10;47(11):1055-61. Epub 2011 Aug 10.

British Columbia Cancer Agency Research Centre, Vancouver, Canada V5Z 1L3.

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http://dx.doi.org/10.1016/j.oraloncology.2011.07.008DOI Listing
November 2011

Arsenic biotransformation as a cancer promoting factor by inducing DNA damage and disruption of repair mechanisms.

Mol Biol Int 2011 2;2011:718974. Epub 2011 Aug 2.

Department of Integrative Oncology, BC Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3.

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http://dx.doi.org/10.4061/2011/718974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200225PMC
November 2011

miR-101 DNA copy loss is a prominent subtype specific event in lung cancer.

J Thorac Oncol 2011 Sep;6(9):1594-8

BC Cancer Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/JTO.0b013e3182217d81DOI Listing
September 2011

MicroRNA gene dosage alterations and drug response in lung cancer.

J Biomed Biotechnol 2011 31;2011:474632. Epub 2011 Mar 31.

British Columbia Cancer Research Centre, Vancouver, BC, Canada.

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http://dx.doi.org/10.1155/2011/474632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085440PMC
August 2011

Deciphering squamous cell carcinoma using multidimensional genomic approaches.

J Skin Cancer 2011 27;2011:541405. Epub 2010 Dec 27.

Department of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, Canada V5Z 1L3.

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http://dx.doi.org/10.1155/2011/541405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017908PMC
July 2011

The functional role of long non-coding RNA in human carcinomas.

Mol Cancer 2011 Apr 13;10:38. Epub 2011 Apr 13.

British Columbia Cancer Agency Research Centre, Vancouver, Canada.

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http://dx.doi.org/10.1186/1476-4598-10-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098824PMC
April 2011

DNA extraction from paraffin embedded material for genetic and epigenetic analyses.

J Vis Exp 2011 Mar 26(49). Epub 2011 Mar 26.

Department of Integrative Oncology, BC Cancer Research Centre, Canada.

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http://dx.doi.org/10.3791/2763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197328PMC
March 2011