Walter J Chazin

Walter J Chazin

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Walter J Chazin

Publications by authors named "Walter J Chazin"

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Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.

MBio 2019 Oct 1;10(5). Epub 2019 Oct 1.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

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http://dx.doi.org/10.1128/mBio.01333-19DOI Listing
October 2019

The novel interaction between Neisseria gonorrhoeae TdfJ and human S100A7 allows gonococci to subvert host zinc restriction.

PLoS Pathog 2019 Aug 1;15(8):e1007937. Epub 2019 Aug 1.

Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692053PMC
August 2019

The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10.

Open Biol 2019 Aug 14;9(8):190117. Epub 2019 Aug 14.

Department of Biochemistry, Molecular Biology and Biophysics, College of Biological Sciences, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1098/rsob.190117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731595PMC
August 2019

S100 Proteins in the Innate Immune Response to Pathogens.

Methods Mol Biol 2019 ;1929:275-290

Department of Biochemistry, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1007/978-1-4939-9030-6_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475579PMC
June 2019

Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs.

PLoS One 2018 18;13(12):e0209345. Epub 2018 Dec 18.

Departments of Biochemistry and Chemistry, and Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209345PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298731PMC
May 2019

Multi-metal Restriction by Calprotectin Impacts De Novo Flavin Biosynthesis in Acinetobacter baumannii.

Cell Chem Biol 2019 May 21;26(5):745-755.e7. Epub 2019 Mar 21.

Department of Chemistry, Indiana University, Bloomington, IN 47405, USA; Department of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24519456193006
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http://dx.doi.org/10.1016/j.chembiol.2019.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525019PMC
May 2019

A new approach to discovery of S100 protein heterodimers.

FEBS J 2019 May 3;286(10):1838-1840. Epub 2019 May 3.

Departments of Biochemistry and Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1111/febs.14851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527480PMC
May 2019

An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration.

Cell Rep 2019 Feb;26(8):2009-2018.e6

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441547PMC
February 2019

Antimicrobial action of calprotectin that does not involve metal withholding.

Metallomics 2018 12;10(12):1728-1742

Department of Biochemistry and Molecular Biology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1039/c8mt00133bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417507PMC
December 2018

Characterization and development of SAPP as a specific peptidic inhibitor that targets Porphyromonas gingivalis.

Mol Oral Microbiol 2018 12 30;33(6):430-439. Epub 2018 Oct 30.

Department of Oral Biology, Meharry Medical College, Nashville, Tennessee.

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http://doi.wiley.com/10.1111/omi.12246
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http://dx.doi.org/10.1111/omi.12246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246824PMC
December 2018

Substrate Binding Regulates Redox Signaling in Human DNA Primase.

J Am Chem Soc 2018 12 29;140(49):17153-17162. Epub 2018 Nov 29.

Division of Chemistry and Chemical Engineering , California Institute of Technology , Pasadena , California 91125 , United States.

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http://pubs.acs.org/doi/10.1021/jacs.8b09914
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http://dx.doi.org/10.1021/jacs.8b09914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470046PMC
December 2018

Yeast require redox switching in DNA primase.

Proc Natl Acad Sci U S A 2018 12 12;115(52):13186-13191. Epub 2018 Dec 12.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125;

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http://dx.doi.org/10.1073/pnas.1810715115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310810PMC
December 2018

Calprotectin protects against experimental colonic inflammation in mice.

Br J Pharmacol 2018 10 2;175(19):3797-3812. Epub 2018 Sep 2.

Department of Pharmacology, CIBERehd, School of Pharmacy, Instituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, Granada, Spain.

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http://dx.doi.org/10.1111/bph.14449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135788PMC
October 2018

A Polymerase With Potential: The Fe-S Cluster in Human DNA Primase.

Methods Enzymol 2017 18;595:361-390. Epub 2017 Aug 18.

Center for Structural Biology, Vanderbilt University, Nashville, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2017.07.002DOI Listing
May 2018

A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel.

Structure 2018 05 5;26(5):683-694.e3. Epub 2018 Apr 5.

Department of Biochemistry, Vanderbilt University, Nashville, TN 37205, USA; Department of Chemistry, Vanderbilt University, Nashville, TN 37235, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09692126183008
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http://dx.doi.org/10.1016/j.str.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932218PMC
May 2018

Analysis of Functional Dynamics of Modular Multidomain Proteins by SAXS and NMR.

Methods Enzymol 2017 17;592:49-76. Epub 2017 Apr 17.

Departments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2017.03.017DOI Listing
April 2018

Role of Calprotectin in Withholding Zinc and Copper from Candida albicans.

Infect Immun 2018 02 22;86(2). Epub 2018 Jan 22.

Department of Biochemistry and Molecular Biology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA

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http://dx.doi.org/10.1128/IAI.00779-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778358PMC
February 2018

Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.

Sci Adv 2018 01 3;4(1):e1701393. Epub 2018 Jan 3.

Department of Chemistry, Center for Diagnostics and Therapeutics, Georgia State University, Atlanta, GA 30303, USA.

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http://dx.doi.org/10.1126/sciadv.1701393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756662PMC
January 2018

Dietary Manganese Promotes Staphylococcal Infection of the Heart.

Cell Host Microbe 2017 Oct 21;22(4):531-542.e8. Epub 2017 Sep 21.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, 1161 21(st) Avenue South, MCN A-5102, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638708PMC
October 2017

RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks.

Mol Cell 2017 Aug 20;67(3):374-386.e5. Epub 2017 Jul 20.

Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548441PMC
August 2017

Prp40 Homolog A Is a Novel Centrin Target.

Biophys J 2017 Jun;112(12):2529-2539

Department of Chemistry, University of Puerto Rico Mayagüez Campus, Mayagüez, Puerto Rico; Protein Research Center, University of Puerto Rico Mayagüez Campus, Mayagüez, Puerto Rico. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479147PMC
June 2017

Molecular basis for PrimPol recruitment to replication forks by RPA.

Nat Commun 2017 05 23;8:15222. Epub 2017 May 23.

Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton BN1 9RQ, UK.

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http://dx.doi.org/10.1038/ncomms15222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457501PMC
May 2017

The [4Fe4S] cluster of human DNA primase functions as a redox switch using DNA charge transport.

Science 2017 02;355(6327)

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1126/science.aag1789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338353PMC
February 2017

ETAA1 acts at stalled replication forks to maintain genome integrity.

Nat Cell Biol 2016 Nov 10;18(11):1185-1195. Epub 2016 Oct 10.

Department of Biochemistry, Vanderbilt University School of Medicine, 613 Light Hall, 2215 Garland Avenue, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1038/ncb3415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5245861PMC
November 2016

Acinetobacter baumannii Coordinates Urea Metabolism with Metal Import To Resist Host-Mediated Metal Limitation.

MBio 2016 Sep 27;7(5). Epub 2016 Sep 27.

Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA Tennessee Valley Healthcare Systems, U.S. Department of Veterans Affairs, Nashville, Tennessee, USA

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http://dx.doi.org/10.1128/mBio.01475-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050338PMC
September 2016

XPA: A key scaffold for human nucleotide excision repair.

DNA Repair (Amst) 2016 08 20;44:123-135. Epub 2016 May 20.

Departments of Biochemistry, Biological Sciences, Biomedical Informatics, Chemistry, and Computer Science, and Vanderbilt Genetics Institute and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-7917, United States. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2016.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958585PMC
August 2016

Binding of transition metals to S100 proteins.

Sci China Life Sci 2016 Aug 19;59(8):792-801. Epub 2016 Jul 19.

Departments of Biochemistry and Chemistry, and Center for Structural Biology, Vanderbilt University, Nashville, TN, 37232-9717, USA.

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http://dx.doi.org/10.1007/s11427-016-5088-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123432PMC
August 2016

Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks.

Circ Arrhythm Electrophysiol 2016 08;9(8)

From the Vanderbilt Center for Arrhythmia Research and Therapeutics (VanCART), Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN (N.G.-H., D.O.K., B.C.K.); Department Molecular Pharmacology & Experimental Therapeutics, Windland Smith Rice Sudden Death Genomics Laboratory (N.J.B., M.L.C., D.J.T., M.J.A.), Department of Cardiovascular Diseases, Division of Heart Rhythm Services (M.J.A.), and Department of Pediatrics, Division of Pediatric Cardiology (M.J.A.), Mayo Clinic, Rochester, MN; Departments of Biochemistry and Chemistry & Center for Structural Biology, Vanderbilt University, Nashville, TN (C.N.J., J.S., W.J.C.); and Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN (F.R.N., R.L.C.).

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http://dx.doi.org/10.1161/CIRCEP.116.004161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988333PMC
August 2016

The Response of Acinetobacter baumannii to Zinc Starvation.

Cell Host Microbe 2016 Jun;19(6):826-36

Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Tennessee Valley Healthcare Systems, US Department of Veterans Affairs, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901392PMC
June 2016

Biochemical and Proteomic Analysis of Ubiquitination of Hsc70 and Hsp70 by the E3 Ligase CHIP.

PLoS One 2015 26;10(5):e0128240. Epub 2015 May 26.

Department of Biochemistry, Vanderbilt University, Nashville, Tennessee, United States of America; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America; Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128240PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4444009PMC
April 2016

CacyBP/SIP--Structure and variety of functions.

Biochim Biophys Acta 2016 Jan 19;1860(1 Pt A):79-85. Epub 2015 Oct 19.

Nencki Institute of Experimental Biology, Warsaw, Poland. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2015.10.012DOI Listing
January 2016

Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection.

J Immunol 2016 Jan 18;196(1):336-44. Epub 2015 Nov 18.

Department of Ophthalmology and Visual Science, Case Western Reserve University, Cleveland, OH 44106; Department of Ophthalmology, University of California, Irvine, Irvine, CA 92697; Department of Physiology and Biophysics, University of California, Irvine, Irvine, CA 92697;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1502037
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http://dx.doi.org/10.4049/jimmunol.1502037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684987PMC
January 2016

Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation.

MBio 2015 Dec 8;6(6):e01349-15. Epub 2015 Dec 8.

Veterans Affairs Tennessee Valley Healthcare Services, Nashville, Tennessee, USA Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee, USA

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http://dx.doi.org/10.1128/mBio.01349-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669380PMC
December 2015

Arrhythmogenic Calmodulin Mutations Affect the Activation and Termination of Cardiac Ryanodine Receptor-mediated Ca2+ Release.

J Biol Chem 2015 Oct 26;290(43):26151-62. Epub 2015 Aug 26.

From the Department of Chemistry and Bioscience, Aalborg University, 9220 Aalborg, Denmark,

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http://dx.doi.org/10.1074/jbc.M115.676627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646266PMC
October 2015

Zinc regulates a switch between primary and alternative S18 ribosomal proteins in Mycobacterium tuberculosis.

Mol Microbiol 2015 Jul 15;97(2):263-80. Epub 2015 May 15.

Division of Infectious Diseases, Boston Children's Hospital/Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1111/mmi.13022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548965PMC
July 2015

The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence.

Infect Immun 2015 Jul 11;83(7):2944-56. Epub 2015 May 11.

Veterans Affairs Tennessee Valley Healthcare Services, Nashville, Tennessee, USA Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA

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http://dx.doi.org/10.1128/IAI.00544-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468547PMC
July 2015

Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface.

J Biol Chem 2015 Jul 8;290(31):18991-8. Epub 2015 Jun 8.

From the Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 and

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http://dx.doi.org/10.1074/jbc.R115.645085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521021PMC
July 2015

Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.

Mol Cell 2015 Jul 2;59(2):176-87. Epub 2015 Jul 2.

Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506714PMC
July 2015

Functional dynamics in replication protein A DNA binding and protein recruitment domains.

Structure 2015 Jun 21;23(6):1028-38. Epub 2015 May 21.

Departments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37232-8725, USA; Department of Chemistry, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.str.2015.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456234PMC
June 2015

Dimerization and phosphatase activity of calcyclin-binding protein/Siah-1 interacting protein: the influence of oxidative stress.

FASEB J 2015 May 21;29(5):1711-24. Epub 2015 Jan 21.

*Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland; Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, USA; and International Institute of Molecular and Cell Biology, Warsaw, Poland

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http://dx.doi.org/10.1096/fj.14-264770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415008PMC
May 2015

Characteristics and concepts of dynamic hub proteins in DNA processing machinery from studies of RPA.

Prog Biophys Mol Biol 2015 Mar 25;117(2-3):206-211. Epub 2014 Dec 25.

Center for Structural Biology and Departments of Biochemistry and Chemistry, Vanderbilt University, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2014.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417437PMC
March 2015

Mechanochemical regulations of RPA's binding to ssDNA.

Sci Rep 2015 Mar 19;5:9296. Epub 2015 Mar 19.

1] Mechanobiology Institute, National University of Singapore, 117411 Singapore [2] Department of Physics, National University of Singapore, 117542 Singapore [3] Centre for Bioimaging Sciences, National University of Singapore, 117546 Singapore.

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http://dx.doi.org/10.1038/srep09296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365408PMC
March 2015

Diphenylpyrazoles as replication protein a inhibitors.

ACS Med Chem Lett 2015 Feb 11;6(2):140-5. Epub 2014 Nov 11.

Department of Biochemistry, Department of Pharmacology, Vanderbilt University School of Medicine, and Department of Chemistry, Vanderbilt University , Nashville, Tennessee 37232, United States.

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http://dx.doi.org/10.1021/ml5003629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329576PMC
February 2015

Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins.

Nucleic Acids Res 2015 Jan 29;43(2):1056-68. Epub 2014 Dec 29.

Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Brighton BN1 9RQ, UK

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http://dx.doi.org/10.1093/nar/gku1321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333378PMC
January 2015

Protein modification by adenine propenal.

Chem Res Toxicol 2014 Oct 24;27(10):1732-42. Epub 2014 Sep 24.

A. B. Hancock Jr. Memorial Laboratory for Cancer Research, Departments of Biochemistry, ‡Chemistry, and §Pharmacology, ∥Mass Spectrometry Research Center, ⊥Center in Molecular Toxicology, #Center for Structural Biology, ∇Department of Medicine, Vanderbilt Institute of Chemical Biology, and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine , Nashville, Tennessee 37232-0146, United States.

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http://dx.doi.org/10.1021/tx500218gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203390PMC
October 2014

The host protein calprotectin modulates the Helicobacter pylori cag type IV secretion system via zinc sequestration.

PLoS Pathog 2014 Oct 16;10(10):e1004450. Epub 2014 Oct 16.

Veterans Affairs Tennessee Valley Healthcare Services, Nashville, Tennessee, United States of America; Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199781PMC
October 2014

Redefining the DNA-binding domain of human XPA.

J Am Chem Soc 2014 Aug 24;136(31):10830-3. Epub 2014 Jul 24.

Departments of Biochemistry and Chemistry, and Center for Structural Biology, Vanderbilt University , Nashville, Tennessee 37232-8725, United States.

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http://dx.doi.org/10.1021/ja503020fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132956PMC
August 2014

Acinetobacter baumannii response to host-mediated zinc limitation requires the transcriptional regulator Zur.

J Bacteriol 2014 Jul 9;196(14):2616-26. Epub 2014 May 9.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

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http://dx.doi.org/10.1128/JB.01650-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097591PMC
July 2014

Structural analysis of replication protein A recruitment of the DNA damage response protein SMARCAL1.

Biochemistry 2014 May 30;53(18):3052-61. Epub 2014 Apr 30.

Department of Biochemistry, ‡Department of Biological Sciences, §Department of Chemistry, and ∥Center for Structural Biology, Vanderbilt University , Nashville, Tennessee 37232, United States.

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http://dx.doi.org/10.1021/bi500252wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4020579PMC
May 2014

Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants.

Circ Res 2014 Mar 21;114(7):1114-24. Epub 2014 Feb 21.

From the Departments of Medicine (H.S.H., M.F., A.L.G., B.C.K.), Biochemistry (C.N.J., W.J.C.), Chemistry (W.J.C.), and Pharmacology (A.L.G., B.C.K.), Vanderbilt University, Nashville, TN; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis (F.R.N., R.L.C.); Department of Pharmacology, University of California, Davis (Y.Y., L.P., D.M.B.); and Department of School of Biomedical Sciences and Pharmacy, University of Newcastle, New South Wales, Australia (K.W., D.L.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.303391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990285PMC
March 2014

Insights into eukaryotic primer synthesis from structures of the p48 subunit of human DNA primase.

J Mol Biol 2014 Feb 13;426(3):558-69. Epub 2013 Nov 13.

Department of Biochemistry, Vanderbilt University, Nashville, TN 37232, USA; Department of Chemistry, Vanderbilt University, Nashville, TN 37232, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2013.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946992PMC
February 2014

Xeroderma pigmentosum complementation group C protein (XPC) serves as a general sensor of damaged DNA.

DNA Repair (Amst) 2013 Nov 17;12(11):947-53. Epub 2013 Sep 17.

Department of Biochemistry, Center for Structural Biology, Center in Molecular Toxicology, and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.dnarep.2013.08.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825762PMC
November 2013

Zinc piracy as a mechanism of Neisseria meningitidis for evasion of nutritional immunity.

PLoS Pathog 2013 Oct 31;9(10):e1003733. Epub 2013 Oct 31.

Department of Molecular Microbiology and Institute of Biomembranes, Utrecht University, Utrecht, Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1003733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814407PMC
October 2013

Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein.

Biochemistry 2013 Sep 6;52(37):6515-24. Epub 2013 Sep 6.

Department of Biochemistry, ‡Department of Chemistry, §Department of Pharmacology, and ∥Center for Structural Biology, Vanderbilt University , Nashville, Tennessee 37232, United States.

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http://dx.doi.org/10.1021/bi400542zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804075PMC
September 2013

Stable RAGE-heparan sulfate complexes are essential for signal transduction.

ACS Chem Biol 2013 Jul 28;8(7):1611-20. Epub 2013 May 28.

Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California, San Diego , La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/cb4001553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806902PMC
July 2013

NMR studies of the interaction of calmodulin with IQ motif peptides.

Methods Mol Biol 2013 ;963:173-86

Department of Biochemistry, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1007/978-1-62703-230-8_11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4011660PMC
June 2013

Activation of UbcH5c~Ub is the result of a shift in interdomain motions of the conjugate bound to U-box E3 ligase E4B.

Biochemistry 2013 Apr 15;52(17):2991-9. Epub 2013 Apr 15.

Department of Biochemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1021/bi3015949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666176PMC
April 2013

A new structural framework for integrating replication protein A into DNA processing machinery.

Nucleic Acids Res 2013 Feb 8;41(4):2313-27. Epub 2013 Jan 8.

Department of Biochemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1093/nar/gks1332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575853PMC
February 2013

Sample preparation methods to analyze DNA-induced structural changes in replication protein A.

Methods Mol Biol 2012 ;922:101-22

Department of Biochemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1007/978-1-62703-032-8_6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713622PMC
January 2013

Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling.

J Exp Med 2012 Dec 3;209(13):2339-50. Epub 2012 Dec 3.

Diabetes Research Program, Division of Endocrinology, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.

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http://www.jem.org/lookup/doi/10.1084/jem.20120873
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http://dx.doi.org/10.1084/jem.20120873DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3526353PMC
December 2012

S100 calcium binding proteins and ion channels.

Front Pharmacol 2012 25;3:67. Epub 2012 Apr 25.

Division of Cellular and Molecular Neurobiology, Department of Cell Biology, University of Salzburg Salzburg, Austria.

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http://dx.doi.org/10.3389/fphar.2012.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336106PMC
October 2012

In support of the BMRB.

Nat Struct Mol Biol 2012 Sep;19(9):854-60

University of Wisconsin-Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1038/nsmb.2371DOI Listing
September 2012

Inhibition of bacterial superoxide defense: a new front in the struggle between host and pathogen.

Virulence 2012 May 1;3(3):325-8. Epub 2012 May 1.

Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.4161/viru.19635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442845PMC
May 2012

Preparation of the modular multi-domain protein RPA for study by NMR spectroscopy.

Methods Mol Biol 2012 ;831:181-95

Departments of Biochemistry and Chemistry, Center for Structural Biology, Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1007/978-1-61779-480-3_11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713611PMC
April 2012

XPF-ERCC1: on the bubble.

Structure 2012 Apr 3;20(4):566-8. Epub 2012 Apr 3.

Department of Biochemistry, Center for Structural Biology, 5140 Biological Sciences/MRB III, Vanderbilt University, Nashville, TN 37232-8725, USA.

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http://dx.doi.org/10.1016/j.str.2012.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525711PMC
April 2012

BID binds to replication protein A and stimulates ATR function following replicative stress.

Mol Cell Biol 2011 Nov 22;31(21):4298-309. Epub 2011 Aug 22.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1128/MCB.05737-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209332PMC
November 2011