Publications

Lysophosphatidylcholine promotes SREBP-2 activation via rapid cholesterol efflux and SREBP-2-independent cytokine release in human endothelial cells.
J Biochem 2015 Oct 21;158(4):331-8. Epub 2015 May 21.
Department of Medical Life Systems, Faculty of Life and Medical Sciences, Doshisha University, Kyoto 610-0321, Japan; and

Shear stress-activated Wnt-angiopoietin-2 signaling recapitulates vascular repair in zebrafish embryos.
Arterioscler Thromb Vasc Biol 2014 Oct 21;34(10):2268-75. Epub 2014 Aug 21.
From the Department of Medicine, School of Medicine (R.L., T.K.H.), Department of Bioengineering (T.B., N.J., F.Y., W.T., H.C., J.L., T.K.H.), and Department of Molecular, Cell, and Developmental Biology (K.W., H.S., J.C.), University of California, Los Angeles; Department of Surgery, Children's Hospital Los Angeles, CA (M.H., C.-L.L.); and Division of Cardiology, Department of Medicine, School of Medicine (H.Y., P.H., N.C.C.) and Institute of Genomic Medicine (N.C.C.), University of California, San Diego, La Jolla.

Disturbed flow enhances inflammatory signaling and atherogenesis by increasing thioredoxin-1 level in endothelial cell nuclei.
PLoS One 2014 29;9(9):e108346. Epub 2014 Sep 29.
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia, United States of America.

The atypical mechanosensitive microRNA-712 derived from pre-ribosomal RNA induces endothelial inflammation and atherosclerosis.
Nat Commun 2013 ;4:3000
1] Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30322, USA [2] Division of Cardiology, Department of Medicine, Emory University, Atlanta, Georgia 30322, USA [3] Department of Bioinspired Science, Ewha Womans University, Seoul 120-750, South Korea.

Oscillatory shear stress induces mitochondrial superoxide production: implication of NADPH oxidase and c-Jun NH2-terminal kinase signaling.
Antioxid Redox Signal 2011 Sep 14;15(5):1379-88. Epub 2011 Apr 14.
Department of Biomedical Engineering and Cardiovascular Medicine, University of Southern California, Los Angeles, California 90089, USA.

Oxidized low-density lipoprotein-activated c-Jun NH2-terminal kinase regulates manganese superoxide dismutase ubiquitination: implication for mitochondrial redox status and apoptosis.
Arterioscler Thromb Vasc Biol 2010 Mar 5;30(3):436-41. Epub 2010 Feb 5.
Department of Biomedical Engineering and Division of Cardiovascular Medicine, School of Medicine and School of Engineering, University of Southern California, 1042 Downey Way, Los Angeles, CA 90089, USA.

Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: role of reactive oxygen/nitrogen species.
Free Radic Biol Med 2007 Jan 20;42(2):260-9. Epub 2006 Oct 20.
Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology (LSBM), University of Tokyo, 4-6-1, Komaba, Meguro, Tokyo 153-8904, Japan.


Expression of the LXRalpha protein in human atherosclerotic lesions.
Arterioscler Thromb Vasc Biol 2005 Mar 29;25(3):622-7. Epub 2004 Dec 29.
Department of Systems Biology and Medicine, Research Center for Advanced Science and Technology, the University of Tokyo, Japan.


Lysophosphatidylcholine enhances cytokine production of endothelial cells via induction of L-type amino acid transporter 1 and cell surface antigen 4F2.
Arterioscler Thromb Vasc Biol 2004 Sep 3;24(9):1640-5. Epub 2004 Jun 3.
Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo, 153-8904, Japan.

The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells.
J Atheroscler Thromb 2002 ;9(4):178-83
Department of Molecular Biology, Research Center for Advanced Science and Technology, University of Tokyo, Meguro, Tokyo, Japan.

OF