Wah-Kheong Chan

Wah-Kheong Chan

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Wah-Kheong Chan

Wah-Kheong Chan

Publications by authors named "Wah-Kheong Chan"

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Editorial: increasing burden of nonalcoholic fatty liver disease-a call to action.

Aliment Pharmacol Ther 2020 Jun;51(12):1429-1430

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/apt.15700DOI Listing
June 2020

Epidemiological differences of common liver conditions between Asia and the West.

JGH Open 2020 Jun 24;4(3):332-339. Epub 2019 Oct 24.

Gastroenterology and Hepatology Unit, Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.

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http://dx.doi.org/10.1002/jgh3.12275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7273710PMC
June 2020

Noninvasive Tests in the Assessment of NASH and NAFLD Fibrosis: Now and Into the Future.

Semin Liver Dis 2020 Jun 11. Epub 2020 Jun 11.

Department of Medicine, Gastroenterology and Hepatology Unit, University of Malaysia, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1055/s-0040-1713006DOI Listing
June 2020

Modest alcohol intake is not associated with significant hepatic steatosis nor more severe liver disease among patient with diabetes mellitus.

J Gastroenterol Hepatol 2020 Jun 24. Epub 2020 Jun 24.

Gastroenterology and Hepatology Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/jgh.15160DOI Listing
June 2020

Management of patients with liver derangement during the COVID-19 pandemic: an Asia-Pacific position statement.

Lancet Gastroenterol Hepatol 2020 Jun 22. Epub 2020 Jun 22.

Department of Medicine and Therapeutics, and Medical Data Analytic Centre, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(20)30190-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308747PMC
June 2020

Allele HLA-DQB1*06 reduces fibrosis score in patients with non-alcoholic fatty liver disease.

Hepatol Res 2020 May 14. Epub 2020 May 14.

Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/hepr.13525DOI Listing
May 2020

Volumetric Liver Fat Fraction Determines Grade of Steatosis More Accurately Than Controlled Attenuation Parameter in Patients With Nonalcoholic Fatty Liver Disease.

Clin Gastroenterol Hepatol 2020 Apr 20;18(4):945-953.e2. Epub 2019 Aug 20.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.08.023DOI Listing
April 2020

Empagliflozin for the Treatment of Nonalcoholic Steatohepatitis in Patients with Type 2 Diabetes Mellitus.

Dig Dis Sci 2020 02 25;65(2):623-631. Epub 2019 Jan 25.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://link.springer.com/10.1007/s10620-019-5477-1
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http://dx.doi.org/10.1007/s10620-019-5477-1DOI Listing
February 2020

Suboptimal treatment of dyslipidemia in patients with nonalcoholic fatty liver disease.

J Gastroenterol Hepatol 2020 Feb 12;35(2):320-325. Epub 2019 Sep 12.

Department of Medicine, Singapore General Hospital, Singapore.

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http://dx.doi.org/10.1111/jgh.14794DOI Listing
February 2020

Epidemiology of non-alcoholic fatty liver disease in Asia.

Indian J Gastroenterol 2020 Feb 9;39(1):1-8. Epub 2020 Mar 9.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12664-020-01018-xDOI Listing
February 2020

Comparing point shear wave elastography (ElastPQ) and transient elastography for diagnosis of fibrosis stage in non-alcoholic fatty liver disease.

J Gastroenterol Hepatol 2020 Jan 29;35(1):135-141. Epub 2019 Jul 29.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/jgh.14782DOI Listing
January 2020

Liver stiffness measurement in non-alcoholic fatty liver disease: Two is better than one.

J Gastroenterol Hepatol 2020 Jan 6. Epub 2020 Jan 6.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/jgh.14978DOI Listing
January 2020

A new bile acid treatment for non-alcoholic fatty liver disease.

Lancet Gastroenterol Hepatol 2019 10 22;4(10):747-749. Epub 2019 Jul 22.

Department of Medicine and Therapeutics and State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China. Electronic address:

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http://dx.doi.org/10.1016/S2468-1253(19)30183-9DOI Listing
October 2019

Limited applicability of cathepsin D for the diagnosis and monitoring of non-alcoholic steatohepatitis.

JGH Open 2019 Oct 4;3(5):417-424. Epub 2019 Apr 4.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.

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http://dx.doi.org/10.1002/jgh3.12178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788371PMC
October 2019

Performance of Simple Fibrosis Scores in Nonobese Patients With Nonalcoholic Fatty Liver Disease.

Clin Gastroenterol Hepatol 2019 Sep 28. Epub 2019 Sep 28.

Centre d'Investigation de la Fibrose Hépatique, Bordeaux University Hospital, Pessac, France; INSERM U1053, Bordeaux University, Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.09.027DOI Listing
September 2019

Screening for non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus using transient elastography.

J Gastroenterol Hepatol 2019 Aug 21;34(8):1396-1403. Epub 2019 Jan 21.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jgh.14577
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http://dx.doi.org/10.1111/jgh.14577DOI Listing
August 2019

Reply to: CHAI and MACK-3 as noninvasive indices for nonalcoholic steatohepatitis.

Liver Int 2019 08 4;39(8):1588. Epub 2019 Jun 4.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/liv.14139
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http://dx.doi.org/10.1111/liv.14139DOI Listing
August 2019

MACK-3 (combination of hoMa, Ast and CK18): A promising novel biomarker for fibrotic non-alcoholic steatohepatitis.

Liver Int 2019 07 18;39(7):1315-1324. Epub 2019 Mar 18.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/liv.14084DOI Listing
July 2019

Association between non-alcoholic fatty liver disease evaluated by transient elastography with extracranial carotid atherosclerosis in a multiethnic Asian community.

JGH Open 2019 Apr 30;3(2):117-125. Epub 2018 Dec 30.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine University Malaya Kuala Lumpur Malaysia.

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http://dx.doi.org/10.1002/jgh3.12114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487823PMC
April 2019

Can the same controlled attenuation parameter cut-offs be used for M and XL probes for diagnosing hepatic steatosis?

J Gastroenterol Hepatol 2018 Oct 7;33(10):1787-1794. Epub 2018 May 7.

Institute of Digestive Disease, The Chinese University of Hong Kong, Sha Tin, Hong Kong.

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http://doi.wiley.com/10.1111/jgh.14150
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http://dx.doi.org/10.1111/jgh.14150DOI Listing
October 2018

Epidemiology of non-alcoholic fatty liver disease-related hepatocellular carcinoma and its implications.

JGH Open 2018 Oct 17;2(5):235-241. Epub 2018 Jul 17.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine University of Malaya Kuala Lumpur Malaysia.

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http://dx.doi.org/10.1002/jgh3.12070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206984PMC
October 2018

Repeated liver stiffness measurement compared with paired liver biopsy in patients with non-alcoholic fatty liver disease.

Hepatol Int 2018 Jan 25;12(1):44-55. Epub 2018 Jan 25.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://link.springer.com/10.1007/s12072-018-9843-4
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http://dx.doi.org/10.1007/s12072-018-9843-4DOI Listing
January 2018

A Randomized Trial of Silymarin for the Treatment of Nonalcoholic Steatohepatitis.

Clin Gastroenterol Hepatol 2017 Dec 15;15(12):1940-1949.e8. Epub 2017 Apr 15.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1016/j.cgh.2017.04.016DOI Listing
December 2017

Endoscopic sleeve gastroplasty: Case report, technique and literature review.

J Dig Dis 2017 Oct;18(10):598-603

Department of Surgery, Federal University of Pernambuco, Recife, Brazil.

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http://dx.doi.org/10.1111/1751-2980.12548DOI Listing
October 2017

Serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in non-alcoholic fatty liver disease.

PLoS One 2017 3;12(4):e0174982. Epub 2017 Apr 3.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0174982PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378406PMC
September 2017

Emerging new standard for non-invasive assessment of liver disease mortality in non-alcoholic fatty liver disease.

Hepatobiliary Surg Nutr 2017 Apr;6(2):135-137

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.21037/hbsn.2017.03.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411272PMC
April 2017

Oxidized low-density lipoprotein in non-alcoholic steatohepatitis.

J Gastroenterol Hepatol 2016 Sep;31(9):1516-8

Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Sha Tin, Hong Kong.

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http://dx.doi.org/10.1111/jgh.13381DOI Listing
September 2016

A novel 2-step approach combining the NAFLD fibrosis score and liver stiffness measurement for predicting advanced fibrosis.

Hepatol Int 2015 Oct 6;9(4):594-602. Epub 2014 Dec 6.

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12072-014-9596-7DOI Listing
October 2015

Sustained complete remission of advanced hepatocellular carcinoma with sorafenib therapy.

J Dig Dis 2015 Sep;16(9):537-40

Gastroenterology and Hepatology Unit, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/1751-2980.12270DOI Listing
September 2015

Low physical activity and energy dense Malaysian foods are associated with non-alcoholic fatty liver disease in centrally obese but not in non-centrally obese patients with diabetes mellitus.

Asia Pac J Clin Nutr 2015 ;24(2):289-98

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.6133/apjcn.2015.24.2.15DOI Listing
August 2015

Limited utility of plasma M30 in discriminating non-alcoholic steatohepatitis from steatosis--a comparison with routine biochemical markers.

PLoS One 2014 3;9(9):e105903. Epub 2014 Sep 3.

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105903PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153577PMC
May 2015

Controlled attenuation parameter for the detection and quantification of hepatic steatosis in nonalcoholic fatty liver disease.

J Gastroenterol Hepatol 2014 ;29(7):1470-6

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://doi.wiley.com/10.1111/jgh.12557
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http://dx.doi.org/10.1111/jgh.12557DOI Listing
March 2015

Progression of liver disease in non-alcoholic fatty liver disease: a prospective clinicopathological follow-up study.

J Dig Dis 2014 Oct;15(10):545-52

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/1751-2980.12175DOI Listing
October 2014

Split-dose vs same-day reduced-volume polyethylene glycol electrolyte lavage solution for morning colonoscopy.

World J Gastroenterol 2014 Oct;20(39):14488-94

Wah-Kheong Chan, Sanjiv Mahadeva, Khean-Lee Goh, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

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http://dx.doi.org/10.3748/wjg.v20.i39.14488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202378PMC
October 2014

Ultrasonography-diagnosed non-alcoholic fatty liver disease is not associated with prevalent ischemic heart disease among diabetics in a multiracial Asian hospital clinic population.

Clin Res Hepatol Gastroenterol 2014 Jun 13;38(3):284-91. Epub 2014 Apr 13.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1016/j.clinre.2014.02.009DOI Listing
June 2014

Non-alcoholic fatty liver disease in a young multiracial Asian population: a worrying ethnic predilection in Malay and Indian males.

Hepatol Int 2014 Jan 3;8(1):121-7. Epub 2014 Jan 3.

Gastroenterology and Hepatology Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12072-013-9510-8DOI Listing
January 2014

Clinical outcomes and direct costings of endoluminal clipping compared to surgery in the management of iatrogenic colonic perforation.

J Dig Dis 2013 Dec;14(12):670-5

Division of Gastroenterology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/1751-2980.12097DOI Listing
December 2013

Non-alcoholic fatty liver disease in diabetics--prevalence and predictive factors in a multiracial hospital clinic population in Malaysia.

J Gastroenterol Hepatol 2013 Aug;28(8):1375-83

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/jgh.12204DOI Listing
August 2013

Cyclosporine rescue therapy in autoimmune liver cirrhosis: a case report.

Turk J Gastroenterol 2012 ;23(5):599-603

University of Malaya, Department of Medicine, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.4318/tjg.2012.0438DOI Listing
May 2013

Epidemiology of a fast emerging disease in the Asia-Pacific region: non-alcoholic fatty liver disease.

Hepatol Int 2013 Mar 15;7(1):65-71. Epub 2012 Jun 15.

Gastroenterology and Hepatology Unit, Gastrointestinal Endoscopy Unit, Department of Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12072-012-9384-1DOI Listing
March 2013

Evaluation of patient satisfaction of an outpatient colonoscopy service in an asian tertiary care hospital.

Gastroenterol Res Pract 2012 23;2012:561893. Epub 2012 Apr 23.

Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2012/561893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347709PMC
August 2012

Evaluation of patient satisfaction of an outpatient gastroscopy service in an Asian tertiary care hospital.

BMC Gastroenterol 2012 Jul 28;12:96. Epub 2012 Jul 28.

Division of Gastroenterology, Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1186/1471-230X-12-96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444441PMC
July 2012

Validation study of the Leeds Dyspepsia Questionnaire in a multi-ethnic Asian population.

J Gastroenterol Hepatol 2011 Nov;26(11):1669-76

Division of Gastroenterology, Department of Medicine, University Malaya Medical Centre, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/j.1440-1746.2011.06806.xDOI Listing
November 2011

Epidemiology of Helicobacter pylori infection and public health implications.

Helicobacter 2011 Sep;16 Suppl 1:1-9

Department of Medicine-Gastroenterology and Hepatology, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1111/j.1523-5378.2011.00874.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719046PMC
September 2011