Publications by authors named "Wah Heng Lee"

13Publications

Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity.

Authors:
Fei Yao Jaya P Kausalya Yee Yen Sia Audrey S M Teo Wah Heng Lee Alicia G M Ong Zhenshui Zhang Joanna H J Tan Guoliang Li Denis Bertrand Xingliang Liu Huay Mei Poh Peiyong Guan Feng Zhu Thushangi Nadeera Pathiraja Pramila N Ariyaratne Jaideepraj Rao Xing Yi Woo Shaojiang Cai Fabianus H Mulawadi Wan Ting Poh Lavanya Veeravalli Chee Seng Chan Seong Soo Lim See Ting Leong Say Chuan Neo Poh Sum D Choi Elaine G Y Chew Niranjan Nagarajan Pierre-Étienne Jacques Jimmy B Y So Xiaoan Ruan Khay Guan Yeoh Patrick Tan Wing-Kin Sung Walter Hunziker Yijun Ruan Axel M Hillmer

Cell Rep 2015 Jul 2;12(2):272-85. Epub 2015 Jul 2.

Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore; The Singapore Gastric Cancer Consortium, National University of Singapore, Singapore 119228, Singapore. Electronic address:

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July 2015

TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome.

Authors:
Sebastian Ribi Daniel Baumhoer Kristy Lee Edison Audrey S M Teo Babita Madan Kang Zhang Wendy K Kohlmann Fei Yao Wah Heng Lee Qiangze Hoi Shaojiang Cai Xing Yi Woo Patrick Tan Gernot Jundt Jan Smida Michaela Nathrath Wing-Kin Sung Joshua D Schiffman David M Virshup Axel M Hillmer

Oncotarget 2015 Apr;6(10):7727-40

Cancer Therapeutics & Stratified Oncology, Genome Institute of Singapore, Singapore 138672, Singapore.

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April 2015

Whole-genome reconstruction and mutational signatures in gastric cancer.

Authors:
Niranjan Nagarajan Denis Bertrand Axel M Hillmer Zhi Jiang Zang Fei Yao Pierre-Étienne Jacques Audrey S M Teo Ioana Cutcutache Zhenshui Zhang Wah Heng Lee Yee Yen Sia Song Gao Pramila N Ariyaratne Andrea Ho Xing Yi Woo Lavanya Veeravali Choon Kiat Ong Niantao Deng Kartiki V Desai Chiea Chuen Khor Martin L Hibberd Atif Shahab Jaideepraj Rao Mengchu Wu Ming Teh Feng Zhu Sze Yung Chin Brendan Pang Jimmy B Y So Guillaume Bourque Richie Soong Wing-Kin Sung Bin Tean Teh Steven Rozen Xiaoan Ruan Khay Guan Yeoh Patrick B O Tan Yijun Ruan

Genome Biol 2012 Dec 13;13(12):R115. Epub 2012 Dec 13.

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December 2012

Long span DNA paired-end-tag (DNA-PET) sequencing strategy for the interrogation of genomic structural mutations and fusion-point-guided reconstruction of amplicons.

Authors:
Fei Yao Pramila N Ariyaratne Axel M Hillmer Wah Heng Lee Guoliang Li Audrey S M Teo Xing Yi Woo Zhenshui Zhang Jieqi P Chen Wan Ting Poh Kelson F B Zawack Chee Seng Chan See Ting Leong Say Chuan Neo Poh Sum D Choi Song Gao Niranjan Nagarajan Hervé Thoreau Atif Shahab Xiaoan Ruan Valère Cacheux-Rataboul Chia-Lin Wei Guillaume Bourque Wing-Kin Sung Edison T Liu Yijun Ruan

PLoS One 2012 28;7(9):e46152. Epub 2012 Sep 28.

Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.

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February 2013

A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer.

Authors:
King Pan Ng Axel M Hillmer Charles T H Chuah Wen Chun Juan Tun Kiat Ko Audrey S M Teo Pramila N Ariyaratne Naoto Takahashi Kenichi Sawada Yao Fei Sheila Soh Wah Heng Lee John W J Huang John C Allen Xing Yi Woo Niranjan Nagarajan Vikrant Kumar Anbupalam Thalamuthu Wan Ting Poh Ai Leen Ang Hae Tha Mya Gee Fung How Li Yi Yang Liang Piu Koh Balram Chowbay Chia-Tien Chang Veera S Nadarajan Wee Joo Chng Hein Than Lay Cheng Lim Yeow Tee Goh Shenli Zhang Dianne Poh Patrick Tan Ju-Ee Seet Mei-Kim Ang Noan-Minh Chau Quan-Sing Ng Daniel S W Tan Manabu Soda Kazutoshi Isobe Markus M Nöthen Tien Y Wong Atif Shahab Xiaoan Ruan Valère Cacheux-Rataboul Wing-Kin Sung Eng Huat Tan Yasushi Yatabe Hiroyuki Mano Ross A Soo Tan Min Chin Wan-Teck Lim Yijun Ruan S Tiong Ong

Nat Med 2012 Mar 18;18(4):521-8. Epub 2012 Mar 18.

Cancer & Stem Cell Biology Signature Research Programme, Duke-National University of Singapore Graduate Medical School, Singapore.

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March 2012

Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes.

Authors:
Axel M Hillmer Fei Yao Koichiro Inaki Wah Heng Lee Pramila N Ariyaratne Audrey S M Teo Xing Yi Woo Zhenshui Zhang Hao Zhao Leena Ukil Jieqi P Chen Feng Zhu Jimmy B Y So Manuel Salto-Tellez Wan Ting Poh Kelson F B Zawack Niranjan Nagarajan Song Gao Guoliang Li Vikrant Kumar Hui Ping J Lim Yee Yen Sia Chee Seng Chan See Ting Leong Say Chuan Neo Poh Sum D Choi Hervé Thoreau Patrick B O Tan Atif Shahab Xiaoan Ruan Jonas Bergh Per Hall Valère Cacheux-Rataboul Chia-Lin Wei Khay Guan Yeoh Wing-Kin Sung Guillaume Bourque Edison T Liu Yijun Ruan

Genome Res 2011 May 5;21(5):665-75. Epub 2011 Apr 5.

Genome Technology and Biology, Genome Institute of Singapore, Singapore 138672, Singapore.

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May 2011

LOMA: a fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens.

Authors:
Wah Heng Lee Christopher W Wong Wan Yee Leong Lance D Miller Wing Kin Sung

BMC Bioinformatics 2008 Sep 10;9:368. Epub 2008 Sep 10.

Genome Institute of Singapore, Genome, Singapore.

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September 2008

RB-finder: an improved distance-based sliding window method to detect recombination breakpoints.

Authors:
Wah-Heng Lee Wing-Kin Sung

J Comput Biol 2008 Sep;15(7):881-98

Genome Institute of Singapore and School of Computing, National University of Singapore, Singapore, Singapore.

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September 2008

The airborne metagenome in an indoor urban environment.

Authors:
Susannah G Tringe Tao Zhang Xuguo Liu Yiting Yu Wah Heng Lee Jennifer Yap Fei Yao Sim Tiow Suan Seah Keng Ing Matthew Haynes Forest Rohwer Chia Lin Wei Patrick Tan James Bristow Edward M Rubin Yijun Ruan

PLoS One 2008 Apr 2;3(4):e1862. Epub 2008 Apr 2.

Department of Energy Joint Genome Institute, Walnut Creek, California, United States of America.

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April 2008

Mapping of transcription factor binding regions in mammalian cells by ChIP: comparison of array- and sequencing-based technologies.

Authors:
Ghia M Euskirchen Joel S Rozowsky Chia-Lin Wei Wah Heng Lee Zhengdong D Zhang Stephen Hartman Olof Emanuelsson Viktor Stolc Sherman Weissman Mark B Gerstein Yijun Ruan Michael Snyder

Genome Res 2007 Jun;17(6):898-909

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, Connecticut 06520-8103, USA.

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June 2007

Fast and accurate probe selection algorithm for large genomes.

Authors:
Wing-Kin Sung Wah-Heng Lee

Proc IEEE Comput Soc Bioinform Conf 2003 ;2:65-74

Department of Computer Science, National University of Singapore, Singapore.

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August 2006

RNA viral community in human feces: prevalence of plant pathogenic viruses.

Authors:
Tao Zhang Mya Breitbart Wah Heng Lee Jin-Quan Run Chia Lin Wei Shirlena Wee Ling Soh Martin L Hibberd Edison T Liu Forest Rohwer Yijun Ruan

PLoS Biol 2006 Jan;4(1):e3

Genome Institute of Singapore, Singapore.

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January 2006

Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003.

Authors:
Vinsensius B Vega Yijun Ruan Jianjun Liu Wah Heng Lee Chia Lin Wei Su Yun Se-Thoe Kin Fai Tang Tao Zhang Prasanna R Kolatkar Eng Eong Ooi Ai Ee Ling Lawrence W Stanton Philip M Long Edison T Liu

BMC Infect Dis 2004 Sep 6;4:32. Epub 2004 Sep 6.

Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672.

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September 2004