Publications by authors named "Wael Zeinyeh"

17Publications

Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity.

Authors:
Lionel Froux Ahmad Elbahnsi Benjamin Boucherle Arnaud Billet Nesrine Baatallah Brice Hoffmann Julien Alliot Renaud Zelli Wael Zeinyeh Romain Haudecoeur Benoit Chevalier Antoine Fortuné Sandra Mirval Christophe Simard Pierre Lehn Jean-Paul Mornon Alexandre Hinzpeter Frédéric Becq Isabelle Callebaut Jean-Luc Décout

Eur J Med Chem 2020 Mar 9;190:112116. Epub 2020 Feb 9.

Univ. Grenoble Alpes, CNRS, DPM, 38000, Grenoble, France.

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March 2020

QSAR Model of Indeno[1,2-]indole Derivatives and Identification of -isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-]furan-3-carboxamide as a Potent CK2 Inhibitor.

Authors:
Samer Haidar Christelle Marminon Dagmar Aichele Abdelhamid Nacereddine Wael Zeinyeh Abdeslem Bouzina Malika Berredjem Laurent Ettouati Zouhair Bouaziz Marc Le Borgne Joachim Jose

Molecules 2019 Dec 26;25(1). Epub 2019 Dec 26.

Institut für Pharmazeutische und Medizinische Chemie, PharmaCampus, Westfälische Wilhelms-Universität Münster, Corrensstr. 48, 48149 Münster, Germany.

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December 2019

Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies.

Authors:
Wael Zeinyeh Yannick J Esvan Béatrice Josselin Blandine Baratte Stéphane Bach Lionel Nauton Vincent Théry Sandrine Ruchaud Fabrice Anizon Francis Giraud Pascale Moreau

Bioorg Med Chem 2019 05 4;27(10):2083-2089. Epub 2019 Apr 4.

Université Clermont Auvergne, CNRS, SIGMA Clermont, ICCF, F-63000 Clermont-Ferrand, France. Electronic address:

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May 2019

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis.

Authors:
Helmi Tazarki Wael Zeinyeh Yannick J Esvan Stefan Knapp Deep Chatterjee Martin Schröder Andreas C Joerger Jameleddine Khiari Béatrice Josselin Blandine Baratte Stéphane Bach Sandrine Ruchaud Fabrice Anizon Francis Giraud Pascale Moreau

Eur J Med Chem 2019 Mar 26;166:304-317. Epub 2019 Jan 26.

Université Clermont Auvergne, CNRS, SIGMA Clermont, ICCF, F-63000, Clermont-Ferrand, France. Electronic address:

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March 2019

Involvement of the Prion Protein in the Protection of the Human Bronchial Epithelial Barrier Against Oxidative Stress.

Authors:
Amal Kouadri Mariam El Khatib Johanna Cormenier Sylvain Chauvet Wael Zeinyeh Micheline El Khoury Laurence Macari Pierre Richaud Christelle Coraux Isabelle Michaud-Soret Nadia Alfaidy Mohamed Benharouga

Antioxid Redox Signal 2019 07 4;31(1):59-74. Epub 2019 Feb 4.

1 University of Grenoble Alpes, CNRS, UMR 5249, CEA, BIG, CBM, Grenoble, France.

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July 2019

6-Chloropurine Ribonucleosides from Chloropyrimidines: One-Pot Synthesis.

Authors:
Renaud Zelli Waël Zeinyeh Jean-Luc Décout

Curr Protoc Nucleic Acid Chem 2018 09 13;74(1):e57. Epub 2018 Aug 13.

Université Grenoble Alpes, CNRS, DPM, Grenoble, France.

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September 2018

In Silico, in Vitro, and in Vivo Evaluation of New Candidates for α-Synuclein PET Imaging.

Authors:
Mathieu Verdurand Elise Levigoureux Wael Zeinyeh Laurent Berthier Meriem Mendjel-Herda Florence Cadarossanesaib Caroline Bouillot Thibault Iecker Raphaël Terreux Sophie Lancelot Fabien Chauveau Thierry Billard Luc Zimmer

Mol Pharm 2018 08 25;15(8):3153-3166. Epub 2018 Jul 25.

Université de Lyon, Université Claude Bernard Lyon 1, Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028 , Lyon 69361 , France.

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August 2018

Amyloid-Beta Radiotracer [F]BF-227 Does Not Bind to Cytoplasmic Glial Inclusions of Postmortem Multiple System Atrophy Brain Tissue.

Authors:
Mathieu Verdurand Elise Levigoureux Sophie Lancelot Waël Zeinyeh Thierry Billard Isabelle Quadrio Armand Perret-Liaudet Luc Zimmer Fabien Chauveau

Contrast Media Mol Imaging 2018 6;2018:9165458. Epub 2018 Feb 6.

Lyon Neuroscience Research Center, CNRS UMR5292, INSERM U1028, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France.

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July 2019

A One-Pot Synthesis of Highly Functionalized Purines.

Authors:
Renaud Zelli Waël Zeinyeh Romain Haudecoeur Julien Alliot Benjamin Boucherle Isabelle Callebaut Jean-Luc Décout

Org Lett 2017 12 10;19(23):6360-6363. Epub 2017 Nov 10.

Univ. Grenoble Alpes , CNRS, DPM, 38000 Grenoble, France.

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December 2017

Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives.

Authors:
Wael Zeinyeh Yannick J Esvan Lionel Nauton Nadège Loaëc Laurent Meijer Vincent Théry Fabrice Anizon Francis Giraud Pascale Moreau

Bioorg Med Chem Lett 2016 09 16;26(17):4327-9. Epub 2016 Jul 16.

Université Clermont Auvergne, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000 Clermont-Ferrand, France; CNRS, UMR 6296, ICCF, F-63178 Aubière, France. Electronic address:

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September 2016

Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure.

Authors:
Yannick J Esvan Wael Zeinyeh Thibaut Boibessot Lionel Nauton Vincent Théry Stefan Knapp Apirat Chaikuad Nadège Loaëc Laurent Meijer Fabrice Anizon Francis Giraud Pascale Moreau

Eur J Med Chem 2016 Aug 5;118:170-7. Epub 2016 Apr 5.

Université Clermont Auvergne, Université Blaise Pascal, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000 Clermont-Ferrand, France; CNRS, UMR 6296, ICCF, F-63178 Aubière, France. Electronic address:

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August 2016

Inverse relationship between hSHBG affinity for testosterone and hSHBG concentration revealed by surface plasmon resonance.

Authors:
Laurence Heinrich-Balard Wael Zeinyeh Henri Déchaud Pascaline Rivory Amandine Roux Michel Pugeat Richard Cohen

Mol Cell Endocrinol 2015 Jan 13;399:201-7. Epub 2014 Oct 13.

Université de Lyon, Lyon F-69000, France; ISPB Faculté de Pharmacie, MATEIS CNRS UMR5510, Université Claude Bernard Lyon-1, 8 Avenue Rockefeller, cedex 08, Lyon F-69373, France; Hôpital Edouard Herriot, Laboratoire de Biochimie et de Biologie Moléculaire, Hospices Civils de Lyon, cedex 03, Lyon 69437, France.

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January 2015

Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2.

Authors:
Gustavo Jabor Gozzi Zouhair Bouaziz Evelyn Winter Nathalia Daflon-Yunes Dagmar Aichele Abdelhamid Nacereddine Christelle Marminon Glaucio Valdameri Waël Zeinyeh Andre Bollacke Jean Guillon Aline Lacoudre Noël Pinaud Silvia M Cadena Joachim Jose Marc Le Borgne Attilio Di Pietro

J Med Chem 2015 Jan 16;58(1):265-77. Epub 2014 Oct 16.

Equipe Labellisée Ligue 2014, BMSSI UMR 5086 CNRS/Université Lyon 1, IBCP, 69367 Lyon, France.

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January 2015

Preparation and characterization of CK2 inhibitor-loaded cyclodextrin nanoparticles for drug delivery.

Authors:
Florent Perret Christelle Marminon Wael Zeinyeh Pascal Nebois Andre Bollacke Joachim Jose Hélène Parrot-Lopez Marc Le Borgne

Int J Pharm 2013 Jan 13;441(1-2):491-8. Epub 2012 Nov 13.

Université de Lyon, Université Lyon 1, CSAp, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, Bâtiment Raulin, 43 Bd du 11 novembre 1918, 69622 Villeurbanne Cedex, France.

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January 2013

Progesterone-adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux: design, synthesis, characterization and biological evaluation.

Authors:
Waël Zeinyeh Zahia Mahiout Sylvie Radix Thierry Lomberget Axel Dumoulin Roland Barret Catherine Grenot Luc Rocheblave Eva-Laure Matera Charles Dumontet Nadia Walchshofer

Steroids 2012 Oct 31;77(12):1177-91. Epub 2012 Jul 31.

Université de Lyon, Université Lyon 1, EA 4446 Biomolécules Cancer Chimiorésistances (B2C), ISPB-Faculté de Pharmacie, UMS 3453 Santé Lyon-Est, 8 Avenue Rockefeller, F-69373 Lyon Cedex 08, France.

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October 2012

Design, synthesis and evaluation of progesterone-adenine hybrids as bivalent inhibitors of P-glycoprotein-mediated multidrug efflux.

Authors:
Waël Zeinyeh Ghina Alameh Sylvie Radix Catherine Grenot Charles Dumontet Nadia Walchshofer

Bioorg Med Chem Lett 2010 May 28;20(10):3165-8. Epub 2010 Mar 28.

Université de Lyon, Université Lyon 1, ISPB-Faculté de Pharmacie, INSERM U863, F-69373 Lyon cedex 08, France.

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May 2010

Synthesis and modulation properties of imidazo[4,5-b]pyridin-7-one and indazole-4,7-dione derivatives towards the Cryptosporidium parvum CpABC3 transporter.

Authors:
Waël Zeinyeh Hexue Xia Philippe Lawton Sylvie Radix Christelle Marminon Pascal Nebois Nadia Walchshofer

Eur J Med Chem 2010 Jun 18;45(6):2480-8. Epub 2010 Feb 18.

Université de Lyon, Université Lyon 1, ISPB-Faculté de Pharmacie, EA 4443 (B2C) Biomolécules, Cancer et Chimiorésistances, 8, av. Rockefeller, F-69373, Lyon Cedex 08, France.

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June 2010