Wade H Berrettini

Wade H Berrettini

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Wade H Berrettini

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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Authors:
Hunna J Watson Zeynep Yilmaz Laura M Thornton Christopher Hübel Jonathan R I Coleman Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Sarah E Medland Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Kirstin L Purves Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Jessica H Baker Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Jaakko Kaprio Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Lars Klareskog Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Melissa A Munn-Chernoff Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op 't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James E Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Garret D Stuber Scott Gordon Jakob Grove Anjali K Henders Anders Juréus Katherine M Kirk Janne T Larsen Richard Parker Liselotte Petersen Jennifer Jordan Martin Kennedy Grant W Montgomery Tracey D Wade Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Nicholas G Martin Preben Bo Mortensen Patrick F Sullivan Gerome Breen Cynthia M Bulik

Nat Genet 2019 Aug 15;51(8):1207-1214. Epub 2019 Jul 15.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/s41588-019-0439-2DOI Listing
August 2019

A review of opioid addiction genetics.

Curr Opin Psychol 2019 Jun 9;27:31-35. Epub 2018 Aug 9.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.copsyc.2018.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368898PMC
June 2019

Replication of the pharmacogenetic effect of rs678849 on buprenorphine efficacy in African-Americans with opioid use disorder.

Pharmacogenomics J 2019 Jun 27;19(3):260-268. Epub 2018 Oct 27.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41397-018-0065-x
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http://dx.doi.org/10.1038/s41397-018-0065-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486881PMC
June 2019

The importance of buprenorphine research in the opioid crisis.

Mol Psychiatry 2019 May 7;24(5):626-632. Epub 2019 Jan 7.

Center for Neurobiology and Behavior, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://www.nature.com/articles/s41380-018-0329-5
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http://dx.doi.org/10.1038/s41380-018-0329-5DOI Listing
May 2019

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Authors:
Eli A Stahl Gerome Breen Andreas J Forstner Andrew McQuillin Stephan Ripke Vassily Trubetskoy Manuel Mattheisen Yunpeng Wang Jonathan R I Coleman Héléna A Gaspar Christiaan A de Leeuw Stacy Steinberg Jennifer M Whitehead Pavlides Maciej Trzaskowski Enda M Byrne Tune H Pers Peter A Holmans Alexander L Richards Liam Abbott Esben Agerbo Huda Akil Diego Albani Ney Alliey-Rodriguez Thomas D Als Adebayo Anjorin Verneri Antilla Swapnil Awasthi Judith A Badner Marie Bækvad-Hansen Jack D Barchas Nicholas Bass Michael Bauer Richard Belliveau Sarah E Bergen Carsten Bøcker Pedersen Erlend Bøen Marco P Boks James Boocock Monika Budde William Bunney Margit Burmeister Jonas Bybjerg-Grauholm William Byerley Miquel Casas Felecia Cerrato Pablo Cervantes Kimberly Chambert Alexander W Charney Danfeng Chen Claire Churchhouse Toni-Kim Clarke William Coryell David W Craig Cristiana Cruceanu David Curtis Piotr M Czerski Anders M Dale Simone de Jong Franziska Degenhardt Jurgen Del-Favero J Raymond DePaulo Srdjan Djurovic Amanda L Dobbyn Ashley Dumont Torbjørn Elvsåshagen Valentina Escott-Price Chun Chieh Fan Sascha B Fischer Matthew Flickinger Tatiana M Foroud Liz Forty Josef Frank Christine Fraser Nelson B Freimer Louise Frisén Katrin Gade Diane Gage Julie Garnham Claudia Giambartolomei Marianne Giørtz Pedersen Jaqueline Goldstein Scott D Gordon Katherine Gordon-Smith Elaine K Green Melissa J Green Tiffany A Greenwood Jakob Grove Weihua Guan José Guzman-Parra Marian L Hamshere Martin Hautzinger Urs Heilbronner Stefan Herms Maria Hipolito Per Hoffmann Dominic Holland Laura Huckins Stéphane Jamain Jessica S Johnson Anders Juréus Radhika Kandaswamy Robert Karlsson James L Kennedy Sarah Kittel-Schneider James A Knowles Manolis Kogevinas Anna C Koller Ralph Kupka Catharina Lavebratt Jacob Lawrence William B Lawson Markus Leber Phil H Lee Shawn E Levy Jun Z Li Chunyu Liu Susanne Lucae Anna Maaser Donald J MacIntyre Pamela B Mahon Wolfgang Maier Lina Martinsson Steve McCarroll Peter McGuffin Melvin G McInnis James D McKay Helena Medeiros Sarah E Medland Fan Meng Lili Milani Grant W Montgomery Derek W Morris Thomas W Mühleisen Niamh Mullins Hoang Nguyen Caroline M Nievergelt Annelie Nordin Adolfsson Evaristus A Nwulia Claire O'Donovan Loes M Olde Loohuis Anil P S Ori Lilijana Oruc Urban Ösby Roy H Perlis Amy Perry Andrea Pfennig James B Potash Shaun M Purcell Eline J Regeer Andreas Reif Céline S Reinbold John P Rice Fabio Rivas Margarita Rivera Panos Roussos Douglas M Ruderfer Euijung Ryu Cristina Sánchez-Mora Alan F Schatzberg William A Scheftner Nicholas J Schork Cynthia Shannon Weickert Tatyana Shehktman Paul D Shilling Engilbert Sigurdsson Claire Slaney Olav B Smeland Janet L Sobell Christine Søholm Hansen Anne T Spijker David St Clair Michael Steffens John S Strauss Fabian Streit Jana Strohmaier Szabolcs Szelinger Robert C Thompson Thorgeir E Thorgeirsson Jens Treutlein Helmut Vedder Weiqing Wang Stanley J Watson Thomas W Weickert Stephanie H Witt Simon Xi Wei Xu Allan H Young Peter Zandi Peng Zhang Sebastian Zöllner Rolf Adolfsson Ingrid Agartz Martin Alda Lena Backlund Bernhard T Baune Frank Bellivier Wade H Berrettini Joanna M Biernacka Douglas H R Blackwood Michael Boehnke Anders D Børglum Aiden Corvin Nicholas Craddock Mark J Daly Udo Dannlowski Tõnu Esko Bruno Etain Mark Frye Janice M Fullerton Elliot S Gershon Michael Gill Fernando Goes Maria Grigoroiu-Serbanescu Joanna Hauser David M Hougaard Christina M Hultman Ian Jones Lisa A Jones René S Kahn George Kirov Mikael Landén Marion Leboyer Cathryn M Lewis Qingqin S Li Jolanta Lissowska Nicholas G Martin Fermin Mayoral Susan L McElroy Andrew M McIntosh Francis J McMahon Ingrid Melle Andres Metspalu Philip B Mitchell Gunnar Morken Ole Mors Preben Bo Mortensen Bertram Müller-Myhsok Richard M Myers Benjamin M Neale Vishwajit Nimgaonkar Merete Nordentoft Markus M Nöthen Michael C O'Donovan Ketil J Oedegaard Michael J Owen Sara A Paciga Carlos Pato Michele T Pato Danielle Posthuma Josep Antoni Ramos-Quiroga Marta Ribasés Marcella Rietschel Guy A Rouleau Martin Schalling Peter R Schofield Thomas G Schulze Alessandro Serretti Jordan W Smoller Hreinn Stefansson Kari Stefansson Eystein Stordal Patrick F Sullivan Gustavo Turecki Arne E Vaaler Eduard Vieta John B Vincent Thomas Werge John I Nurnberger Naomi R Wray Arianna Di Florio Howard J Edenberg Sven Cichon Roel A Ophoff Laura J Scott Ole A Andreassen John Kelsoe Pamela Sklar

Nat Genet 2019 05 1;51(5):793-803. Epub 2019 May 1.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://www.nature.com/articles/s41588-019-0397-8
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http://dx.doi.org/10.1038/s41588-019-0397-8DOI Listing
May 2019

Dr Nurnberger and Colleagues Reply.

J Clin Psychiatry 2019 Apr 9;80(3). Epub 2019 Apr 9.

Centre for Addiction and Mental Health and University of Toronto, Toronto, Ontario, Canada.

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https://www.psychiatrist.com/JCP/article/Pages/2019/v80/19lr
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http://dx.doi.org/10.4088/JCP.19lr12741aDOI Listing
April 2019

Environmental, genetic and epigenetic contributions to cocaine addiction.

Neuropsychopharmacology 2018 06 5;43(7):1471-1480. Epub 2018 Feb 5.

Department of Psychology, Temple University, Philadelphia, PA, 19122, USA.

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http://dx.doi.org/10.1038/s41386-018-0008-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983541PMC
June 2018

Pharmacogenetics of Opioid Use Disorder Treatment.

CNS Drugs 2018 04;32(4):305-320

Translational Research Laboratories, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, 125 South 31st Street, Room 2207, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s40263-018-0513-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935553PMC
April 2018

Pharmacogenetic analysis of opioid dependence treatment dose and dropout rate.

Am J Drug Alcohol Abuse 2018 15;44(4):431-440. Epub 2018 Jan 15.

a Center for Neurobiology and Behavior, Department of Psychiatry , University of Pennsylvania School of Medicine , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/00952990.2017.1420795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940523PMC
January 2018

Analysis of LINE-1 Elements in DNA from Postmortem Brains of Individuals with Schizophrenia.

Neuropsychopharmacology 2017 Dec 6;42(13):2602-2611. Epub 2017 Jun 6.

Translational Research Laboratories, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/npp.2017.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686486PMC
December 2017

Failure to Replicate an Association of a LINE-1 Element in ERI1 Exoribonuclease Family Member 3 (ERI3) with Schizophrenia.

Neuropsychopharmacology 2017 12;42(13):2471

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania Perelman School of Medicine, Translational Research Laboratories, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/npp.2017.145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686490PMC
December 2017

Reading LINEs within the cocaine addicted brain.

Brain Behav 2017 05 6;7(5):e00678. Epub 2017 Apr 6.

Department of Psychiatry Center for Neurobiology and Behavior University of Pennsylvania Perelman School of Medicine Philadelphia PA USA.

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http://dx.doi.org/10.1002/brb3.678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434184PMC
May 2017

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Authors:
Liping Hou Sarah E Bergen Nirmala Akula Jie Song Christina M Hultman Mikael Landén Mazda Adli Martin Alda Raffaella Ardau Bárbara Arias Jean-Michel Aubry Lena Backlund Judith A Badner Thomas B Barrett Michael Bauer Bernhard T Baune Frank Bellivier Antonio Benabarre Susanne Bengesser Wade H Berrettini Abesh Kumar Bhattacharjee Joanna M Biernacka Armin Birner Cinnamon S Bloss Clara Brichant-Petitjean Elise T Bui William Byerley Pablo Cervantes Caterina Chillotti Sven Cichon Francesc Colom William Coryell David W Craig Cristiana Cruceanu Piotr M Czerski Tony Davis Alexandre Dayer Franziska Degenhardt Maria Del Zompo J Raymond DePaulo Howard J Edenberg Bruno Étain Peter Falkai Tatiana Foroud Andreas J Forstner Louise Frisén Mark A Frye Janice M Fullerton Sébastien Gard Julie S Garnham Elliot S Gershon Fernando S Goes Tiffany A Greenwood Maria Grigoroiu-Serbanescu Joanna Hauser Urs Heilbronner Stefanie Heilmann-Heimbach Stefan Herms Maria Hipolito Shashi Hitturlingappa Per Hoffmann Andrea Hofmann Stephane Jamain Esther Jiménez Jean-Pierre Kahn Layla Kassem John R Kelsoe Sarah Kittel-Schneider Sebastian Kliwicki Daniel L Koller Barbara König Nina Lackner Gonzalo Laje Maren Lang Catharina Lavebratt William B Lawson Marion Leboyer Susan G Leckband Chunyu Liu Anna Maaser Pamela B Mahon Wolfgang Maier Mario Maj Mirko Manchia Lina Martinsson Michael J McCarthy Susan L McElroy Melvin G McInnis Rebecca McKinney Philip B Mitchell Marina Mitjans Francis M Mondimore Palmiero Monteleone Thomas W Mühleisen Caroline M Nievergelt Markus M Nöthen Tomas Novák John I Nurnberger Evaristus A Nwulia Urban Ösby Andrea Pfennig James B Potash Peter Propping Andreas Reif Eva Reininghaus John Rice Marcella Rietschel Guy A Rouleau Janusz K Rybakowski Martin Schalling William A Scheftner Peter R Schofield Nicholas J Schork Thomas G Schulze Johannes Schumacher Barbara W Schweizer Giovanni Severino Tatyana Shekhtman Paul D Shilling Christian Simhandl Claire M Slaney Erin N Smith Alessio Squassina Thomas Stamm Pavla Stopkova Fabian Streit Jana Strohmaier Szabolcs Szelinger Sarah K Tighe Alfonso Tortorella Gustavo Turecki Eduard Vieta Julia Volkert Stephanie H Witt Adam Wright Peter P Zandi Peng Zhang Sebastian Zollner Francis J McMahon

Hum Mol Genet 2016 08 21;25(15):3383-3394. Epub 2016 Jun 21.

Intramural Research Program, National Institute of Mental Health, National Institutes of Health,U.S. Department of Health & Human Services, Bethesda, MD, USA,

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http://dx.doi.org/10.1093/hmg/ddw181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179929PMC
August 2016

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.

Authors:
Liping Hou Sarah E Bergen Nirmala Akula Jie Song Christina M Hultman Mikael Landén Mazda Adli Martin Alda Raffaella Ardau Bárbara Arias Jean-Michel Aubry Lena Backlund Judith A Badner Thomas B Barrett Michael Bauer Bernhard T Baune Frank Bellivier Antonio Benabarre Susanne Bengesser Wade H Berrettini Abesh Kumar Bhattacharjee Joanna M Biernacka Armin Birner Cinnamon S Bloss Clara Brichant-Petitjean Elise T Bui William Byerley Pablo Cervantes Caterina Chillotti Sven Cichon Francesc Colom William Coryell David W Craig Cristiana Cruceanu Piotr M Czerski Tony Davis Alexandre Dayer Franziska Degenhardt Maria Del Zompo J Raymond DePaulo Howard J Edenberg Bruno Étain Peter Falkai Tatiana Foroud Andreas J Forstner Louise Frisén Mark A Frye Janice M Fullerton Sébastien Gard Julie S Garnham Elliot S Gershon Fernando S Goes Tiffany A Greenwood Maria Grigoroiu-Serbanescu Joanna Hauser Urs Heilbronner Stefanie Heilmann-Heimbach Stefan Herms Maria Hipolito Shashi Hitturlingappa Per Hoffmann Andrea Hofmann Stephane Jamain Esther Jiménez Jean-Pierre Kahn Layla Kassem John R Kelsoe Sarah Kittel-Schneider Sebastian Kliwicki Daniel L Koller Barbara König Nina Lackner Gonzalo Laje Maren Lang Catharina Lavebratt William B Lawson Marion Leboyer Susan G Leckband Chunyu Liu Anna Maaser Pamela B Mahon Wolfgang Maier Mario Maj Mirko Manchia Lina Martinsson Michael J McCarthy Susan L McElroy Melvin G McInnis Rebecca McKinney Philip B Mitchell Marina Mitjans Francis M Mondimore Palmiero Monteleone Thomas W Mühleisen Caroline M Nievergelt Markus M Nöthen Tomas Novák John I Nurnberger Evaristus A Nwulia Urban Ösby Andrea Pfennig James B Potash Peter Propping Andreas Reif Eva Reininghaus John Rice Marcella Rietschel Guy A Rouleau Janusz K Rybakowski Martin Schalling William A Scheftner Peter R Schofield Nicholas J Schork Thomas G Schulze Johannes Schumacher Barbara W Schweizer Giovanni Severino Tatyana Shekhtman Paul D Shilling Christian Simhandl Claire M Slaney Erin N Smith Alessio Squassina Thomas Stamm Pavla Stopkova Fabian Streit Jana Strohmaier Szabolcs Szelinger Sarah K Tighe Alfonso Tortorella Gustavo Turecki Eduard Vieta Julia Volkert Stephanie H Witt Adam Wright Peter P Zandi Peng Zhang Sebastian Zollner Francis J McMahon

Hum Mol Genet 2016 08 21;25(15):3383-3394. Epub 2016 Jun 21.

Intramural Research Program, National Institute of Mental Health, National Institutes of Health,U.S. Department of Health & Human Services, Bethesda, MD, USA,

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http://dx.doi.org/10.1093/hmg/ddw181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5179929PMC
August 2016

Somatic DNA Variation in Brain as a Source of Risk for CNS Diseases.

Neuropsychopharmacology 2016 Jan;41(1):386-7

Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1038/npp.2015.302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677153PMC
January 2016

Pharmacogenetics of OPRM1.

Pharmacol Biochem Behav 2014 Aug 5;123:25-33. Epub 2013 Nov 5.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, 125 South 31st St., Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.pbb.2013.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010567PMC
August 2014

Characterization of genetic variation in the VGLL4 gene in anorexia nervosa.

Psychiatr Genet 2014 Aug;24(4):183-4

aDepartment of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia bDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania cDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland dDepartment of Psychiatry, University of Minnesota, Minneapolis, Minnesota eNew York Presbyterian Hospital-Westchester Division, Weill Medical College of Cornell, University, White Plains, New York fEating Recovery Center, Denver, Colorado gDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina hNeuropsychiatric Research Institute, Fargo iDepartment of Clinical Neuroscience, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota jDepartment of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles kCenter for Health Sciences, SRI International, Menlo Park lDepartment of Psychiatry, University of California at San Diego, San Diego mScripps Genomic Medicine, The Scripps Research Institute, La Jolla, California nDepartment of Psychology, Florida State University, Tallahassee, Florida oDepartment of Psychology, Michigan State University, East Lansing, Michigan pClinical Psychology Program, American School of Professional Psychology at Argosy University, Washington, District of Columbia, USA qRoseneck Hospital for Behavioral Medicine, Prien rDepartment of Psychiatry, University of Munich (LMU), Munich, Germany sCenter for Addiction and Mental Health tDepartment of Psychiatry, Toronto General Hospital, University Health Network uDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada vDepartment of Psychiatry, Neurobiology, Pharmacology, and Biotechnology, University of Pisa, Pisa, Italy wDepartment of Academic Psychiatry, Bermondsey Wing Guys Hospital, University of London, London, UK xBrain Mind Institute EPFL - Lausanne and Center for Psyc

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http://dx.doi.org/10.1097/YPG.0000000000000040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104366PMC
August 2014

Identification of CHRNA5 rare variants in African-American heavy smokers.

Psychiatr Genet 2014 Jun;24(3):102-9

Department of Psychiatry, Perelman School of Medicine, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/YPG.0000000000000029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015337PMC
June 2014

Morphine-induced trafficking of a mu-opioid receptor interacting protein in rat locus coeruleus neurons.

Prog Neuropsychopharmacol Biol Psychiatry 2014 Apr 12;50:53-65. Epub 2013 Dec 12.

Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, PA 19102, United States.

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http://dx.doi.org/10.1016/j.pnpbp.2013.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928604PMC
April 2014

The dopamine receptor D2 (DRD2) SNP rs1076560 is associated with opioid addiction.

Ann Hum Genet 2014 Jan 25;78(1):33-9. Epub 2013 Nov 25.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.

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http://doi.wiley.com/10.1111/ahg.12046
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http://dx.doi.org/10.1111/ahg.12046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013426PMC
January 2014

An intronic variant in OPRD1 predicts treatment outcome for opioid dependence in African-Americans.

Neuropsychopharmacology 2013 Sep 23;38(10):2003-10. Epub 2013 Apr 23.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2013.99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746708PMC
September 2013

Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.

Addict Biol 2013 Jul 25;18(4):702-8. Epub 2011 Jul 25.

Psychiatric Pharmacogenetics Laboratory Center for Neurobiology and Behavior Treatment Research Center Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2011.00346.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223560PMC
July 2013

Case-control association study of WLS variants in opioid and cocaine addicted populations.

Psychiatry Res 2013 Jun 5;208(1):62-6. Epub 2013 Apr 5.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.psychres.2013.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665700PMC
June 2013

Low frequency genetic variants in the μ-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.

Neurosci Lett 2013 May 20;542:71-5. Epub 2013 Feb 20.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2013.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640707PMC
May 2013

Development of home cage social behaviors in BALB/cJ vs. C57BL/6J mice.

Behav Brain Res 2013 Jan 5;237:338-47. Epub 2012 Sep 5.

Center for Neurobiology and Behavior, Department of Psychiatry, Perelman School of Medicine at University of Pennsylvania, Translational Research Laboratory, 125 South 31st Street, Room 2220, Philadelphia, PA 19104-3403, USA.

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http://dx.doi.org/10.1016/j.bbr.2012.08.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554266PMC
January 2013

Re-sequencing of ankyrin 3 exon 48 and case-control association analysis of rare variants in bipolar disorder type I.

Bipolar Disord 2012 Dec 11;14(8):809-21. Epub 2012 Sep 11.

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/bdi.12002DOI Listing
December 2012

Neuronal calcium sensor-1 and cocaine addiction: a genetic association study in African-Americans and European Americans.

Neurosci Lett 2012 Nov 20;531(1):46-51. Epub 2012 Sep 20.

Psychiatric Pharmacogenetics Laboratory, Center for Neurobiology and Behavior, Department of Psychiatry, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2012.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895491PMC
November 2012

Association study of the β-arrestin 2 gene (ARRB2) with opioid and cocaine dependence in a European-American population.

Psychiatr Genet 2012 Jun;22(3):141-5

Translational Research Laboratory, Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, 125 S. 31st St, School of Medicine, Rm. 2109, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/YPG.0b013e3283539528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920286PMC
June 2012

Sociability and brain development in BALB/cJ and C57BL/6J mice.

Behav Brain Res 2012 Mar 9;228(2):299-310. Epub 2011 Dec 9.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Translational Research Laboratory, 125 South 31st Street, Philadelphia, PA 19104-3403, USA.

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http://dx.doi.org/10.1016/j.bbr.2011.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474345PMC
March 2012

In vitro and ex vivo analysis of CHRNA3 and CHRNA5 haplotype expression.

PLoS One 2011 12;6(8):e23373. Epub 2011 Aug 12.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023373PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155531PMC
February 2012

Association analysis between polymorphisms in the myo-inositol monophosphatase 2 (IMPA2) gene and bipolar disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2010 Dec 26;34(8):1515-9. Epub 2010 Aug 26.

Psychiatric Pharmacogenetics Laboratory, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.pnpbp.2010.08.015DOI Listing
December 2010

Association analysis between polymorphisms in the conserved dopamine neurotrophic factor (CDNF) gene and cocaine dependence.

Neurosci Lett 2009 Apr 21;453(3):199-203. Epub 2009 Feb 21.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.neulet.2009.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680755PMC
April 2009

Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence.

Neuropsychopharmacology 2008 Dec 13;33(13):3078-84. Epub 2008 Aug 13.

Department of Psychiatry, Translational Research Laboratories, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2008.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583214PMC
December 2008

Fine mapping of a major QTL influencing morphine preference in C57BL/6 and DBA/2 mice using congenic strains.

Neuropsychopharmacology 2008 Nov 20;33(12):2801-9. Epub 2008 Feb 20.

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2008.14DOI Listing
November 2008

Variation in the genes encoding vesicular monoamine transporter 2 and beta-1 adrenergic receptor and antidepressant treatment outcome.

Psychiatr Genet 2008 Oct;18(5):248-51

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1097/YPG.0b013e3283052ff7DOI Listing
October 2008

Association between polymorphisms in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) on chromosome 8p and schizophrenia.

Neuropsychobiology 2008 2;57(1-2):55-60. Epub 2008 May 2.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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https://www.karger.com/Article/FullText/129668
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http://dx.doi.org/10.1159/000129668DOI Listing
September 2008

Association between polymorphisms in the vesicle-associated membrane protein-associated protein A (VAPA) gene on chromosome 18p and bipolar disorder.

J Neural Transm (Vienna) 2008 Sep 30;115(9):1339-45. Epub 2008 Jul 30.

Department of Psychiatry, Translational Research Laboratories, University of Pennsylvania School of Medicine, Center for Neurobiology and Behavior, 125 South 31st Street, Room 2213, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1007/s00702-008-0093-9DOI Listing
September 2008

Genetic variants in the cocaine- and amphetamine-regulated transcript gene (CARTPT) and cocaine dependence.

Neurosci Lett 2008 Aug 24;440(3):280-3. Epub 2008 May 24.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.neulet.2008.05.073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507865PMC
August 2008

Fine mapping of a major QTL influencing morphine preference in C57BL/6 and DBA/2 mice using congenic strains.

Neuropsychopharmacology 2008 Nov 20;33(12):2801-9. Epub 2008 Feb 20.

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/npp.2008.14DOI Listing
November 2008

Association analysis of the pituitary adenylate cyclase-activating polypeptide (PACAP/ADCYAP1) gene in bipolar disorder.

Psychiatr Genet 2008 Apr;18(2):53-8

Department of Psychiatry, Translational Research Laboratory, Center for Neurobiology and Behavior, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104 USA.

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http://dx.doi.org/10.1097/YPG.0b013e3282f60320DOI Listing
April 2008

Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.

Physiol Genomics 2007 Nov 14;31(3):458-62. Epub 2007 Aug 14.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104-3404, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00123.2007DOI Listing
November 2007

Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer.

Epilepsia 2007 Sep 23;48(9):1667-1677. Epub 2007 May 23.

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PennsylvaniaResearch Service, Veteran's Affairs Medical Center, Coatesville, PennsylvaniaDepartment of Neurology, University of Cincinnati, Cincinnati, Ohio, U.S.A.

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http://dx.doi.org/10.1111/j.1528-1167.2007.01126.xDOI Listing
September 2007

Transcriptional profiling of C57 and DBA strains of mice in the absence and presence of morphine.

BMC Genomics 2007 Mar 16;8:76. Epub 2007 Mar 16.

Department of Psychiatry, University of Medicine and Dentistry of New Jersey/New Jersey Medical School, Newark, NJ, USA.

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http://dx.doi.org/10.1186/1471-2164-8-76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1851712PMC
March 2007

Identification of three mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.

Gene 2007 Feb 1;388(1-2):135-47. Epub 2006 Nov 1.

The Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.

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http://dx.doi.org/10.1016/j.gene.2006.10.017DOI Listing
February 2007

Catechol-O-methyltransferase (COMT) gene variants predict response to bupropion therapy for tobacco dependence.

Biol Psychiatry 2007 Jan 28;61(1):111-8. Epub 2006 Jul 28.

Department of Psychiatry, Transdisciplinary Tobacco Use Research Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.04.030DOI Listing
January 2007

Variations in the vesicular monoamine transporter 1 gene (VMAT1/SLC18A1) are associated with bipolar i disorder.

Neuropsychopharmacology 2006 Dec 23;31(12):2739-47. Epub 2006 Aug 23.

Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/sj.npp.1301196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2507868PMC
December 2006

Pharmacogenomic evaluation of the antidepressant citalopram in the mouse tail suspension test.

Neuropsychopharmacology 2006 Nov 22;31(11):2433-42. Epub 2006 Mar 22.

Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1038/sj.npp.1301065DOI Listing
November 2006

Smoking in eating disorders.

Eat Behav 2006 Nov 27;7(4):291-9. Epub 2006 Jun 27.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7160, USA.

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http://dx.doi.org/10.1016/j.eatbeh.2006.06.005DOI Listing
November 2006

No evidence for a major role of polymorphisms during bupropion treatment.

Obesity (Silver Spring) 2006 Nov;14(11):1863-7

Department of Biostatistics, Section on Statistical Genetics, Ryals Public Health Building, Suite 327, University of Alabama at Birmingham, 1665 University Boulevard, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1038/oby.2006.215DOI Listing
November 2006

No association between polymorphisms in the prostate apoptosis factor-4 gene and cocaine dependence.

Psychiatr Genet 2006 Oct;16(5):193-6

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1097/01.ypg.0000218618.73257.8dDOI Listing
October 2006

Features associated with excessive exercise in women with eating disorders.

Int J Eat Disord 2006 Sep;39(6):454-61

Department of Psychiatry, University of North Carolina, Chapel Hill, NC 27599-7160, and Center for Eating Disorders at Sheppard and Enoch Pratt Hospital, Towson, MD, USA.

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http://dx.doi.org/10.1002/eat.20247DOI Listing
September 2006

Targeting treatments for alcohol dependence: the pharmacogenetics of naltrexone.

Addict Biol 2006 Sep;11(3-4):397-403

University of Pennsylvania, Geriartric and Addiction Psychiatry, philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1111/j.1369-1600.2006.00036.xDOI Listing
September 2006

Identification and functional significance of polymorphisms in the mu-opioid receptor gene (Oprm) promoter of C57BL/6 and DBA/2 mice.

Neurosci Res 2006 Jul 27;55(3):244-54. Epub 2006 Apr 27.

The Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S016801020600068
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http://dx.doi.org/10.1016/j.neures.2006.03.005DOI Listing
July 2006

Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia.

Nat Med 2006 Jul 11;12(7):824-8. Epub 2006 Jun 11.

Cellular and Molecular Neuropathology Program, Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/nm1418DOI Listing
July 2006

Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients.

Psychopharmacology (Berl) 2006 Mar 17;185(1):123-32. Epub 2006 Jan 17.

Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC 27704, USA.

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http://dx.doi.org/10.1007/s00213-005-0261-7DOI Listing
March 2006

Analysis of variations in the NAPG gene on chromosome 18p11 in bipolar disorder.

Psychiatr Genet 2006 Feb;16(1):3-8

Center for Neurobiology and Behavior, Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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February 2006

Genetic bases for endophenotypes in psychiatric disorders.

Dialogues Clin Neurosci 2005 ;7(2):95-101

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania, 415 Curie Boulevard, Room 111, Philadelphia, PA 19107, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3181728PMC
December 2005

Lack of association between variations in the melanocortin 5 receptor gene and bipolar disorder.

Psychiatr Genet 2005 Dec;15(4):255-8

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, 19104-6140, USA.

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December 2005

Association of a polymorphism in the Homer1 gene with cocaine dependence in an African American population.

Psychiatr Genet 2005 Dec;15(4):277-83

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Clinical Research Building, Philadelphia, 19104, USA.

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December 2005

A functional prodynorphin promoter polymorphism and opioid dependence.

Psychiatr Genet 2005 Dec;15(4):295-8

Department of Pharmacology, University of Pennsylvania, Philadelphia, 19104, USA.

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http://pdfs.journals.lww.com/psychgenetics/2005/12000/A_func
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December 2005

Promising pharmacotherapy on the horizon for nicotine dependence.

Psychiatry (Edgmont) 2005 Dec;2(12):40-3

Dr. Berrettini is the Karl E. Rickels Professor of Psychiatry, Director, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994239PMC
December 2005

Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence.

Am J Med Genet B Neuropsychiatr Genet 2005 Nov;139B(1):106-8

Department of Psychiatry, Center for Neurobiology and Behavior, University of Pennsylvania School of Medicine, Clinical Research Building, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/ajmg.b.30238DOI Listing
November 2005