Wendy M Purcell

Wendy M Purcell

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Wendy M Purcell

Wendy M Purcell

Publications by authors named "Wendy M Purcell"

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21Publications

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Spheroid Size Does not Impact Metabolism of the β-blocker Propranolol in 3D Intestinal Fish Model.

Front Pharmacol 2018 22;9:947. Epub 2018 Aug 22.

School of Biological and Marine Sciences, University of Plymouth, Plymouth, United Kingdom.

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http://dx.doi.org/10.3389/fphar.2018.00947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113889PMC
August 2018

In-vitro maintenance and functionality of primary renal tubules and their application in the study of relative renal toxicity of nephrotoxic drugs.

J Pharmacol Toxicol Methods 2013 Sep-Oct;68(2):269-274. Epub 2013 Feb 28.

School of Biomedical and Biological Sciences, Plymouth University, Plymouth, UK.

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http://dx.doi.org/10.1016/j.vascn.2013.02.007DOI Listing
March 2014

Nociceptin-induced modulation of human T cell function.

Peptides 2009 May 6;30(5):926-34. Epub 2009 Feb 6.

Faculty of Health and Life Sciences, Centre for Research in Biomedicine, University of the West of England, Coldharbour lane, Frenchay, Bristol, UK.

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http://dx.doi.org/10.1016/j.peptides.2009.01.021DOI Listing
May 2009

Functional three-dimensional HepG2 aggregate cultures generated from an ultrasound trap: comparison with HepG2 spheroids.

J Cell Biochem 2007 Dec;102(5):1180-9

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1002/jcb.21345DOI Listing
December 2007

Energy metabolism and biotransformation as endpoints to pre-screen hepatotoxicity using a liver spheroid model.

Toxicol Appl Pharmacol 2006 Oct 27;216(2):293-302. Epub 2006 May 27.

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol, Frenchay Campus, Coldharbour Lane, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1016/j.taap.2006.05.015DOI Listing
October 2006

Electrophysiological measurements in three-dimensional in vivo-mimetic organotypic cell cultures: preliminary studies with hen embryo brain spheroids.

Neurosci Lett 2006 Aug 5;404(1-2):33-8. Epub 2006 Jun 5.

Faculty of Applied Sciences, University of the West of England, Bristol, UK.

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http://dx.doi.org/10.1016/j.neulet.2006.05.016DOI Listing
August 2006

Nociceptin/orphanin FQ modulates human T cell function in vitro.

J Neuroimmunol 2004 Apr;149(1-2):110-20

Faculty of Applied Sciences, Centre for Research in Biomedicine, University of the West of England, Coldharbour Lane, Frenchay, Bristol, BS16 1QY, UK.

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http://dx.doi.org/10.1016/j.jneuroim.2003.12.018DOI Listing
April 2004

Peroxynitrite mediates nitric oxide-induced blood-brain barrier damage.

Neurochem Res 2004 Mar;29(3):579-87

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol, United Kingdom BS16 1QY.

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http://dx.doi.org/10.1023/b:nere.0000014828.32200.bdDOI Listing
March 2004

Biochemical and functional changes of rat liver spheroids during spheroid formation and maintenance in culture: I. morphological maturation and kinetic changes of energy metabolism, albumin synthesis, and activities of some enzymes.

J Cell Biochem 2003 Dec;90(6):1166-75

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol, United Kingdom.

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http://dx.doi.org/10.1002/jcb.10730DOI Listing
December 2003

Biochemical and functional changes of rat liver spheroids during spheroid formation and maintenance in culture: II. nitric oxide synthesis and related changes.

J Cell Biochem 2003 Dec;90(6):1176-85

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol, United Kingdom.

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http://dx.doi.org/10.1002/jcb.10731DOI Listing
December 2003

Cryopreservation of organotypic brain spheroid cultures.

Altern Lab Anim 2003 Dec;31(6):563-73

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Coldharbour Lane, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1177/026119290303100605DOI Listing
December 2003

Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. I. Glucose metabolism and enzyme release as cytotoxic markers.

Toxicol Appl Pharmacol 2003 Jun;189(2):100-11

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol BS161QY, UK.

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http://dx.doi.org/10.1016/s0041-008x(03)00089-9DOI Listing
June 2003

Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. II. Spheroid cell spreading inhibition as a new cytotoxic marker.

Toxicol Appl Pharmacol 2003 Jun;189(2):112-9

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol BS161QY, UK.

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http://dx.doi.org/10.1016/s0041-008x(03)00090-5DOI Listing
June 2003

Optimizing the enzymatic determination of galactose in the culture medium of rat liver and HepG2 cell spheroids.

Anal Biochem 2002 Dec;311(2):179-81

Centre for Research in Biomedicine, Faculty of Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.

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http://dx.doi.org/10.1016/s0003-2697(02)00400-1DOI Listing
December 2002

Activated T cells mediate direct blood-brain barrier endothelial cell death and dysfunction.

Neuroreport 2002 Dec;13(18):2587-91

Department of Neurochemistry, Institute of Neurology, University College of London, London WC1N 3BG, UK.

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http://dx.doi.org/10.1097/00001756-200212200-00041DOI Listing
December 2002

Evaluation of the role of P-glycoprotein in inflammation induced blood-brain barrier damage.

Neuroreport 2002 Dec;13(18):2593-7

Department of Neurochemistry, Institute of Neurology, Univeristy College London, London WC1N 3BG, UK.

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http://dx.doi.org/10.1097/00001756-200212200-00042DOI Listing
December 2002