Vrushank Dave

Vrushank Dave

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Vrushank Dave

Vrushank Dave

Publications by authors named "Vrushank Dave"

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26Publications

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Analyzing aggregation propensities of clinically relevant PTEN mutants: a new culprit in pathogenesis of cancer and other PTENopathies.

J Biomol Struct Dyn 2019 Jun 22:1-14. Epub 2019 Jun 22.

a Department of Pathology and Cell Biology, Morsani College of Medicine , University of South Florida , Tampa , FL , USA.

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http://dx.doi.org/10.1080/07391102.2019.1630005DOI Listing
June 2019

PTEN proteoforms in biology and disease.

Cell Mol Life Sci 2017 08 13;74(15):2783-2794. Epub 2017 Mar 13.

Department of Pathology and Cell Biology, Morsani College of Medicine, MDC 64, University of South Florida, 12901 Bruce B Downs Blvd, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1007/s00018-017-2500-6DOI Listing
August 2017

Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis.

Cell Death Discov 2017 10;3:17010. Epub 2017 Apr 10.

Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1038/cddiscovery.2017.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385413PMC
April 2017

Data on evolution of intrinsically disordered regions of the human kinome and contribution of FAK1 IDRs to cytoskeletal remodeling.

Data Brief 2017 Feb 8;10:315-324. Epub 2016 Dec 8.

Morsani College of Medicine, Department of Pathology and Cell Biology, University of South Florida, Tampa, FL 33612, USA; Department of Cancer Biology and Evolution, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1016/j.dib.2016.11.099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157709PMC
February 2017

Structural pliability adjacent to the kinase domain highlights contribution of FAK1 IDRs to cytoskeletal remodeling.

Biochim Biophys Acta Proteins Proteom 2017 Jan 5;1865(1):43-54. Epub 2016 Oct 5.

Morsani College of Medicine, Department of Pathology and Cell Biology, University of South Florida, Tampa, FL 33612, United States; Department of Cancer Biology and Evolution, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15709639163020
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http://dx.doi.org/10.1016/j.bbapap.2016.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127739PMC
January 2017

Identification of intrinsically disordered regions in PTEN and delineation of its function via a network approach.

Methods 2015 May 15;77-78:69-74. Epub 2014 Oct 15.

Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, United States; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2014.10.005DOI Listing
May 2015

Integrating omics technologies to study pulmonary physiology and pathology at the systems level.

Cell Physiol Biochem 2014 28;33(5):1239-60. Epub 2014 Apr 28.

Morsani College of Medicine, Department of Pathology and Cell Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://dx.doi.org/10.1159/000358693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396816PMC
April 2015

Presence and utility of intrinsically disordered regions in kinases.

Mol Biosyst 2014 Nov;10(11):2876-88

Morsani College of Medicine, Department of Pathology and Cell Biology, University of South Florida, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1039/c4mb00224eDOI Listing
November 2014

Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseases.

Chem Rev 2014 Jul 15;114(13):6844-79. Epub 2014 May 15.

Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute and ∥Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida , Tampa, Florida 33612, United States.

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http://pubs.acs.org/doi/10.1021/cr400713r
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http://dx.doi.org/10.1021/cr400713rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4100540PMC
July 2014

Intrinsic disorder in PTEN and its interactome confers structural plasticity and functional versatility.

Sci Rep 2013 ;3:2035

Morsani College of Medicine, Department of Pathology and Cell Biology, University of South Florida, Tampa, FL 33612, USA

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http://www.nature.com/articles/srep02035
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http://dx.doi.org/10.1038/srep02035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687229PMC
June 2014

One mouse, one patient paradigm: New avatars of personalized cancer therapy.

Cancer Lett 2014 Mar 22;344(1):1-12. Epub 2013 Oct 22.

Morsani College of Medicine, Department of Pathology and Cell Biology, Tampa, FL 33612, USA; Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2013.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092874PMC
March 2014

The PTEN Long N-tail is intrinsically disordered: increased viability for PTEN therapy.

Mol Biosyst 2013 Nov;9(11):2877-88

Morsani College of Medicine, MDC 64, Department of Pathology and Cell Biology, University of South Florida, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1039/c3mb70267gDOI Listing
November 2013

A systems approach to mapping transcriptional networks controlling surfactant homeostasis.

BMC Genomics 2010 Jul 26;11:451. Epub 2010 Jul 26.

Division of Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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http://dx.doi.org/10.1186/1471-2164-11-451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091648PMC
July 2010

Signaling pathways in the epithelial origins of pulmonary fibrosis.

Cell Cycle 2010 Jul 3;9(14):2769-76. Epub 2010 Jul 3.

Department of Pediatrics, Pulmonary Medicine, University of California, San Diego, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040960PMC
http://dx.doi.org/10.4161/cc.9.14.12268DOI Listing
July 2010

Conditional deletion of Pten causes bronchiolar hyperplasia.

Am J Respir Cell Mol Biol 2008 Mar 5;38(3):337-45. Epub 2007 Oct 5.

Division of Pulmonary Biology, 4403, Cincinnati Children's Hospital Research Foundation, University of Cincinnati Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1165/rcmb.2007-0182OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258453PMC
March 2008

Transcriptional control of lung morphogenesis.

Physiol Rev 2007 Jan;87(1):219-44

Division of Pulmonary Biology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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http://www.physiology.org/doi/10.1152/physrev.00028.2006
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http://dx.doi.org/10.1152/physrev.00028.2006DOI Listing
January 2007

Calcineurin/Nfat signaling is required for perinatal lung maturation and function.

J Clin Invest 2006 Oct 21;116(10):2597-609. Epub 2006 Sep 21.

Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1172/JCI27331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570374PMC
October 2006

PARP-2 interacts with TTF-1 and regulates expression of surfactant protein-B.

J Biol Chem 2006 Apr 6;281(14):9600-6. Epub 2006 Feb 6.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1074/jbc.M510435200DOI Listing
April 2006

The solution structure of the native K50 Bicoid homeodomain bound to the consensus TAATCC DNA-binding site.

J Mol Biol 2006 Mar 22;356(5):1137-51. Epub 2005 Dec 22.

Department of Molecular Genetics, Biochemistry, and Microbiology, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Medical Sciences Building, Cincinnati, OH 45267-0524, USA.

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http://dx.doi.org/10.1016/j.jmb.2005.12.007DOI Listing
March 2006

Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome.

Biochemistry 2005 May;44(20):7497-511

Department of Molecular Genetics, Biochemistry, and Microbiology, College of Medicine, University of Cincinnati, 231 Albert Sabin Way, Medical Sciences Building, Cincinnati, Ohio 45267-0524, USA.

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http://dx.doi.org/10.1021/bi0473253DOI Listing
May 2005

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells.

J Biol Chem 2004 Aug 1;279(33):34578-88. Epub 2004 Jun 1.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1074/jbc.M404296200DOI Listing
August 2004

A composite motif of the Drosophila morphogenetic protein bicoid critical to transcription control.

J Biol Chem 2003 Nov 25;278(45):43901-9. Epub 2003 Aug 25.

Division of Developmental Biology, Children's Hospital Research Foundation, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1074/jbc.M302714200DOI Listing
November 2003

The activity of the Drosophila morphogenetic protein Bicoid is inhibited by a domain located outside its homeodomain.

Development 2002 Apr;129(7):1669-80

Division of Developmental Biology, Children's Hospital Research Foundation, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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April 2002