Publications



Genetic evolution of uveal melanoma guides the development of an inflammatory microenvironment.
Cancer Immunol Immunother 2017 Jul 8;66(7):903-912. Epub 2017 Apr 8.
Department of Ophthalmology, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, The Netherlands.



Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma.
Cancer Cell 2017 Feb 2;31(2):181-193. Epub 2017 Feb 2.
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:


BRG1/SMARCA4 inactivation promotes non-small cell lung cancer aggressiveness by altering chromatin organization.
Cancer Res 2014 Nov 12;74(22):6486-6498. Epub 2014 Aug 12.
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina , USA.

Integrated RNA and DNA sequencing improves mutation detection in low purity tumors.
Nucleic Acids Res 2014 Jul 26;42(13):e107. Epub 2014 Jun 26.
Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA Department of Internal Medicine, Division of Medical Oncology, Multidisciplinary Thoracic Oncology Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

Cancer-derived mutations in KEAP1 impair NRF2 degradation but not ubiquitination.
Cancer Res 2014 Feb 9;74(3):808-17. Epub 2013 Dec 9.
Authors' Affiliations: Department of Cell Biology and Physiology; Lineberger Comprehensive Cancer Center; and Division of Medical Oncology, Department of Internal Medicine and Otolaryngology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; and Department of Pharmacology, Howard Hughes Medical Institute, University of Washington, Seattle, Washington.




Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC.
PLoS One 2015 15;10(6):e0129280. Epub 2015 Jun 15.
Lineberger Comprehensive Cancer Center, the University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, United States of America; Department of Medicine, the University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, United States of America.

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