Vladimir Y Toshchakov

Vladimir Y Toshchakov

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Vladimir Y Toshchakov

Vladimir Y Toshchakov

Publications by authors named "Vladimir Y Toshchakov"

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16Publications

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Targeting the TLR signalosome with TIR domain-derived cell-permeable decoy peptides: the current state and perspectives.

Innate Immun 2020 01;26(1):35-47

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/1753425919844310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6974878PMC
January 2020

A survey of TIR domain sequence and structure divergence.

Immunogenetics 2020 Jan 30. Epub 2020 Jan 30.

Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

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http://dx.doi.org/10.1007/s00251-020-01157-7DOI Listing
January 2020

Frontline Science: Targeting the TLR7 signalosome assembly.

J Leukoc Biol 2019 Oct 22. Epub 2019 Oct 22.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/JLB.2HI0819-180RDOI Listing
October 2019

Blocking TIR Domain Interactions in TLR9 Signaling.

J Immunol 2018 08 18;201(3):995-1006. Epub 2018 Jun 18.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201; and

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http://dx.doi.org/10.4049/jimmunol.1800194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6057823PMC
August 2018

Differential adapter recruitment by TLR2 co-receptors.

Pathog Dis 2016 07 4;74(5). Epub 2016 May 4.

Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 West Baltimore St., HSFI, Baltimore, MD 21201, USA

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http://dx.doi.org/10.1093/femspd/ftw043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985480PMC
July 2016

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza.

Cell Rep 2015 Jun 18;11(12):1941-52. Epub 2015 Jun 18.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490105PMC
June 2015

Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain.

Proc Natl Acad Sci U S A 2013 Nov 5;110(47):19036-41. Epub 2013 Nov 5.

Departments of Microbiology and Immunology, Medicine, and Microbiology and Immunology, and Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD 21201.

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http://dx.doi.org/10.1073/pnas.1313575110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839745PMC
November 2013

Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivo.

J Immunol 2013 Mar 23;190(5):2263-72. Epub 2013 Jan 23.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.4049/jimmunol.1202703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578136PMC
March 2013

Targeting Toll-like receptor (TLR) signaling by Toll/interleukin-1 receptor (TIR) domain-containing adapter protein/MyD88 adapter-like (TIRAP/Mal)-derived decoy peptides.

J Biol Chem 2012 Jul 30;287(29):24641-8. Epub 2012 May 30.

Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M112.360925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397892PMC
July 2012

Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity.

J Biol Chem 2008 Sep 11;283(36):24314-25. Epub 2008 Jul 11.

Department of Microbiology and Immunology, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M804800200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528983PMC
September 2008

Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages.

J Immunol 2007 Jul;179(1):236-46

Department of Microbiology and Immunology, School of Medicine, University of Maryland, 660 West Redwood Street, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.4049/jimmunol.179.1.236DOI Listing
July 2007

Cell-penetrating TIR BB loop decoy peptides a novel class of TLR signaling inhibitors and a tool to study topology of TIR-TIR interactions.

Expert Opin Biol Ther 2007 Jul;7(7):1035-50

University of Maryland, Department of Microbiology and Immunology, School of Medicine, MD 21201-1559, Baltimore, USA.

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http://dx.doi.org/10.1517/14712598.7.7.1035DOI Listing
July 2007

Cutting Edge: Differential inhibition of TLR signaling pathways by cell-permeable peptides representing BB loops of TLRs.

J Immunol 2007 Mar;178(5):2655-60

Department of Microbiology and Immunology, University of Maryland-Baltimore, 660 West Redwood Street, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.4049/jimmunol.178.5.2655DOI Listing
March 2007