Publications by authors named "Vladimir Lupashin"

59Publications

Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection.

mSphere 2020 11 11;5(6). Epub 2020 Nov 11.

Université de Strasbourg, Architecture et Réactivité de l'ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, Strasbourg, France

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November 2020

Novel role for the Golgi membrane protein TMEM165 in control of migration and invasion for breast carcinoma.

Oncotarget 2020 Jul 14;11(28):2747-2762. Epub 2020 Jul 14.

University of Oklahoma Health Sciences Center, Department of Biochemistry and Molecular Biology, Oklahoma City, OK, United States.

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July 2020

Golgi inCOGnito: From vesicle tethering to human disease.

Biochim Biophys Acta Gen Subj 2020 11 27;1864(11):129694. Epub 2020 Jul 27.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address:

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November 2020

Editorial: Golgi Dynamics in Physiological and Pathological Conditions.

Front Cell Dev Biol 2020 29;8. Epub 2020 Jan 29.

Department of Biomedicine and Molecular Imaging Center, University of Bergen, Bergen, Norway.

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January 2020

Retraction Note: Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability.

Sci Rep 2019 Sep 27;9(1):14218. Epub 2019 Sep 27.

Departments of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, US.

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September 2019

Fetal bovine serum impacts the observed N-glycosylation defects in TMEM165 KO HEK cells.

J Inherit Metab Dis 2020 03 1;43(2):357-366. Epub 2019 Oct 1.

CNRS, UMR 8576, Unité de Glycobiologie Structurale et Fonctionnelle (UGSF), Université de Lille, Lille, France.

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March 2020

Maintaining order: COG complex controls Golgi trafficking, processing, and sorting.

FEBS Lett 2019 09 16;593(17):2466-2487. Epub 2019 Aug 16.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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September 2019

Dissection of TMEM165 function in Golgi glycosylation and its Mn sensitivity.

Biochimie 2019 Oct 24;165:123-130. Epub 2019 Jul 24.

Univ. Lille, CNRS, UMR 8576 - UGSF - Unité de Glycobiologie Structurale et Fonctionnelle, F- 59000, Lille, France. Electronic address:

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October 2019

Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells.

Front Cell Dev Biol 2019 3;7:118. Epub 2019 Jul 3.

Department of Physiology, University of Arkansas for Medical Sciences, Little Rock, AR, United States.

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July 2019

Detailed Analysis of the Interaction of Yeast COG Complex.

Cell Struct Funct 2018 Jul 14;43(2):119-127. Epub 2018 Jun 14.

Live Cell Super-Resolution Imaging Research Team, RIKEN Center for Advanced Photonics.

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July 2018

More than just sugars: Conserved oligomeric Golgi complex deficiency causes glycosylation-independent cellular defects.

Traffic 2018 06 24;19(6):463-480. Epub 2018 Apr 24.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

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June 2018

Membrane detachment is not essential for COG complex function.

Mol Biol Cell 2018 04 30;29(8):964-974. Epub 2018 Mar 30.

College of Medicine, Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205.

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April 2018

Conserved Oligomeric Golgi and Neuronal Vesicular Trafficking.

Handb Exp Pharmacol 2018 ;245:227-247

College of Medicine, Physiology and Biophysics, UAMS, Little Rock, AR, USA.

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September 2018

A Brucella Type IV Effector Targets the COG Tethering Complex to Remodel Host Secretory Traffic and Promote Intracellular Replication.

Cell Host Microbe 2017 Sep 24;22(3):317-329.e7. Epub 2017 Aug 24.

Paul G. Allen School for Global Animal Health, Washington State University, Pullman, WA 99164, USA. Electronic address:

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September 2017

Galactose Supplementation in Patients With TMEM165-CDG Rescues the Glycosylation Defects.

J Clin Endocrinol Metab 2017 Apr;102(4):1375-1386

Université Lille, Centre National de la Recherche Française, UMR 8576-Unité de Glycobiologie Structurale et Fonctionnelle-Unité de Glycobiologie Structurale et Fonctionnelle, F-59000 Lille, France.

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April 2017

Manganese-induced turnover of TMEM165.

Biochem J 2017 04 19;474(9):1481-1493. Epub 2017 Apr 19.

CNRS, UMR 8576 - UGSF - Unité de Glycobiologie Structurale et Fonctionnelle, Université de Lille, Lille F-59000, France and the LIA GLYCOLAB4CDG France/ Belgium (International Associated Laboratory "Laboratory for the Research on Congenital Disorders of Glycosylation - from cellular mechanisms to cure")

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April 2017

High-magnification super-resolution FINCH microscopy using birefringent crystal lens interferometers.

Nat Photonics 2016 Dec 14;10:802-808. Epub 2016 Nov 14.

Department of Biomedical Engineering, Johns Hopkins University, 9605 Medical Center Drive Suite 240, Rockville, Maryland 20850, USA.; Microscopy Center, Johns Hopkins University Montgomery County Campus, Rockville, Maryland 20850, USA.; CellOptic, Inc., 9605 Medical Center Drive Suite 224, Rockville, Maryland 20850, USA.

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December 2016

Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway.

J Cell Physiol 2017 Dec 12;232(12):3520-3529. Epub 2017 Apr 12.

Departments of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas.

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December 2017

COG Complex Complexities: Detailed Characterization of a Complete Set of HEK293T Cells Lacking Individual COG Subunits.

Front Cell Dev Biol 2016 30;4:23. Epub 2016 Mar 30.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences Little Rock, AR, USA.

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April 2016

Identification of Rab41/6d Effectors Provides an Explanation for the Differential Effects of Rab41/6d and Rab6a/a' on Golgi Organization.

Front Cell Dev Biol 2016 1;4:13. Epub 2016 Mar 1.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences Little Rock, AR, USA.

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March 2016

Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability.

Sci Rep 2016 Mar 9;6:22747. Epub 2016 Mar 9.

Departments of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, US.

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March 2016

Defects in the COG complex and COG-related trafficking regulators affect neuronal Golgi function.

Front Neurosci 2015 27;9:405. Epub 2015 Oct 27.

Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences Little Rock, AR, USA.

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November 2015

Expression of functional Myc-tagged conserved oligomeric Golgi (COG) subcomplexes in mammalian cells.

Methods Mol Biol 2015 ;1270:167-77

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 505, Little Rock, AR, 72205, USA.

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November 2015

The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection.

J Immunol 2014 Sep 28;193(5):2394-404. Epub 2014 Jul 28.

Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;

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September 2014

Multipronged interaction of the COG complex with intracellular membranes.

Cell Logist 2014 Jan 13;4(1):e27888. Epub 2014 Feb 13.

Department of Physiology and Biophysics; UAMS; Little Rock, AR USA.

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January 2014

Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs.

Mol Biol Cell 2013 Nov 18;24(22):3534-44. Epub 2013 Sep 18.

Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo 113-0033, Japan Pathological Cell Biology Laboratory, Graduate School of Pharmaceutical Sciences, University of Tokyo, Tokyo 113-0033, Japan Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205.

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November 2013

The Golgi puppet master: COG complex at center stage of membrane trafficking interactions.

Histochem Cell Biol 2013 Sep 10;140(3):271-83. Epub 2013 Jul 10.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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September 2013

Fluorescent microscopy as a tool to elucidate dysfunction and mislocalization of Golgi glycosyltransferases in COG complex depleted mammalian cells.

Methods Mol Biol 2013 ;1022:61-72

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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January 2014

COG6 interacts with a subset of the Golgi SNAREs and is important for the Golgi complex integrity.

Traffic 2013 Feb 12;14(2):194-204. Epub 2012 Nov 12.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

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February 2013

Mislocalization of large ARF-GEFs as a potential mechanism for BFA resistance in COG-deficient cells.

Exp Cell Res 2011 Oct 22;317(16):2342-52. Epub 2011 Jun 22.

Complex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.

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October 2011

Conserved oligomeric Golgi complex specifically regulates the maintenance of Golgi glycosylation machinery.

Glycobiology 2011 Dec 18;21(12):1554-69. Epub 2011 Mar 18.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 505, Little Rock, AR 72205, USA.

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December 2011

Role of vesicle tethering factors in the ER-Golgi membrane traffic.

FEBS Lett 2009 Dec 1;583(23):3770-83. Epub 2009 Nov 1.

Department of Cell Biology, University of Alabama at Birmingham, 1918 University Boulevard, Birmingham, AL 35294, USA.

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December 2009

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.

Proc Natl Acad Sci U S A 2009 Aug 27;106(32):13329-34. Epub 2009 Jul 27.

Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

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August 2009

The cellular distribution of serotonin transporter is impeded on serotonin-altered vimentin network.

PLoS One 2009 9;4(3):e4730. Epub 2009 Mar 9.

Department of Biochemistry and Molecular Biology, College of Medicine, The University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.

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May 2009

Role of the conserved oligomeric Golgi (COG) complex in protein glycosylation.

Carbohydr Res 2008 Aug 2;343(12):2024-31. Epub 2008 Feb 2.

Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, Biomed 261-2, Slot 505, 200 South Cedar St., Little Rock, AR 72205, USA.

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August 2008

Serotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporter.

J Biol Chem 2008 Apr 28;283(14):9388-98. Epub 2008 Jan 28.

Department of Biochemistry and Molecular Biology, College of Medicine, University of Arkansas for Medical Sciences, 301 West Markham Street, Little Rock, AR 72205, USA.

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April 2008

Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability.

J Cell Biol 2007 Dec;179(6):1179-92

Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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December 2007

Rab6 regulates both ZW10/RINT-1 and conserved oligomeric Golgi complex-dependent Golgi trafficking and homeostasis.

Mol Biol Cell 2007 Oct 15;18(10):4129-42. Epub 2007 Aug 15.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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October 2007

Molecular and clinical characterization of a Moroccan Cog7 deficient patient.

Mol Genet Metab 2007 Jun 28;91(2):201-4. Epub 2007 Mar 28.

Department of Glycobiology and Carbohydrate Chemistry, Burnham Institute for Medical Research, La Jolla, CA 92037, USA.

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June 2007

COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation.

Traffic 2006 Feb;7(2):191-204

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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February 2006

Role of tethering factors in secretory membrane traffic.

Am J Physiol Cell Physiol 2006 Jan;290(1):C11-26

Dept. of Cell Biology, Univ. of Alabama at Birmingham, 1918 Univ. Blvd., Birmingham, AL 35294, USA.

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January 2006

Golgi tethering factors.

Biochim Biophys Acta 2005 Jul 14;1744(3):325-39. Epub 2005 Apr 14.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Biomed 261-2, Slot 505, 200 South Cedar St, Little Rock, AR 72205, USA.

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July 2005

Cog1p plays a central role in the organization of the yeast conserved oligomeric Golgi complex.

J Biol Chem 2005 Jul 2;280(30):27613-23. Epub 2005 Jun 2.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

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July 2005

Cog3p depletion blocks vesicle-mediated Golgi retrograde trafficking in HeLa cells.

J Cell Biol 2005 Feb 22;168(5):747-59. Epub 2005 Feb 22.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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February 2005

The Sec34/Sec35p complex, a Ypt1p effector required for retrograde intra-Golgi trafficking, interacts with Golgi SNAREs and COPI vesicle coat proteins.

J Cell Biol 2002 May 13;157(4):631-43. Epub 2002 May 13.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.

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May 2002