Publications

Concomitant vascular and neurodegenerative pathologies double the risk of dementia.
Alzheimers Dement 2018 Feb 30;14(2):148-156. Epub 2017 Sep 30.
Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:

The upgoing thumb sign: An interobserver/intraobserver reliability study.
Neurol Clin Pract 2017 Dec;7(6):483-487
Department of Clinical Neurological Sciences, University Hospital (SA, MRA, LS, VH), Stroke, Dementia and Heart Disease Laboratory, Department of Anatomy and Cell Biology (LS) and Department of Epidemiology and Biostatics (MRA, VH), the University of Western Ontario, London; Dr. Everett Chalmers Regional Hospital (SA), Fredericton Medical Clinic, Dalhousie University, New Brunswick, Canada; and Department of Neurology (MRA), Ghaem Hospital, Mashhad University of Medical Sciences, Iran.

Comprehensive Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attack or Mild Stroke: PSYCHOLOGICAL PROFILE AND OUTCOMES.
J Cardiopulm Rehabil Prev 2017 Nov;37(6):428-436
Cardiac Rehabilitation and Secondary Prevention Program, St Joseph's Hospital, Ontario, Canada (Drs Prior and Suskin and Ms Unsworth); Clinical Neurological Sciences (Drs Hachinski, Chan, and Harnadek) and Southwestern Ontario Stroke Strategy (Ms Mytka), London Health Sciences Centre, Ontario, Canada; Lawson Health Research Institute, Ontario, Canada (Drs Prior and Suskin); Stroke Services, Cardiac Care Network of Ontario, Ontario, Canada (Ms O'Callaghan); and Western University, Ontario, Canada (Drs Hachinski, Chan, Harnadek, and Suskin).

Time is brain: Balancing risk in the treatment of presumed cardioembolic stroke.
J Neurol Sci 2017 Nov 21;382:157-160. Epub 2017 Jul 21.
Department of Clinical Neurological Sciences, University Hospital, London Health Science Center, The University of Western Ontario, Ontario, Canada; Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:

Blood pressure at age 60-65 versus age 70-75 and vascular dementia: a population based observational study.
BMC Geriatr 2017 Oct 27;17(1):252. Epub 2017 Oct 27.
Department of Medicine, Physiology and Pharmacology and Community Health Sciences, O'Brien Institute for Public Health and Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, AB, T2N 1N4, Canada.

Behavioural inflexibility in a comorbid rat model of striatal ischemic injury and mutant hAPP overexpression.
Behav Brain Res 2017 Aug 8;333:267-275. Epub 2017 Jul 8.
Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, Western University, London ON, Canada. Electronic address:

Association of Dual-Task Gait With Incident Dementia in Mild Cognitive Impairment: Results From the Gait and Brain Study.
JAMA Neurol 2017 Jul;74(7):857-865
Gait and Brain Lab, Parkwood Institute and Lawson Health Research Institute, London, Ontario, Canada10Faculty of Health Sciences, School of Kinesiology, University of Western Ontario, London, Ontario, Canada.

Upgoing thumb sign: A sensitive indicator of brain involvement?
Neurology 2017 Jul 28;89(4):370-375. Epub 2017 Jun 28.
From the Department of Clinical Neurological Sciences (V.H., R.A., M.R.A.), University Hospital, London Health Sciences Center, University of Western Ontario; Department of Epidemiology and Biostatistics (V.H., M.R.A.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; and Department of Neurology (M.R.A.), Ghaem Hospital, Mashhad University of Medical Sciences, Iran.




The Healthy Mind, Healthy Mobility Trial: A Novel Exercise Program for Older Adults.
Med Sci Sports Exerc 2016 Feb;48(2):297-306
1Department of Family Medicine, Western University, London, ON, CANADA; 2Aging, Rehabilitation & Geriatric Care Research Centre, Lawson Health Research Institute, London, ON, CANADA; 3Department of Epidemiology & National Alzheimer's Coordinating Center, University of Washington, Seattle, WA; 4School of Health and Rehabilitation Sciences, Western University, London, ON, CANADA; 5Department of Epidemiology & Biostatistics, Western University, London, ON, CANADA; 6Robarts Clinical Trials of Robarts Research Institute, Western University, London, ON, CANADA; 7Department of Physical Therapy, University of British Columbia, Vancouver, BC, CANADA; 8Djavad Mowafaghian Centre for Brain Health, Vancouver, BC, CANADA; 9Faculty of Education, Mie University, JAPAN; 10Department of Clinical Neurological Sciences, Western University, London, ON, CANADA; 11Canadian Centre for Activity and Aging, Faculty of Health Sciences, Western University, London, ON, CANADA; and 12School of Kinesiology, Western University, London, ON, CANADA.


Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database.
Neurobiol Aging 2015 Oct 3;36(10):2861-8. Epub 2015 Jul 3.
Department of Clinical Neurological Sciences, London Health Sciences Centre, Western Ontario University, London, Ontario, Canada.

Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and TIA: a systematic review and meta-analysis.
Int J Stroke 2015 Aug 6;10(6):801-7. Epub 2015 Jul 6.
Stroke Outcomes Research Center, Division of Neurology, Department of Medicine, St. Michael's Hospital and Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

Amyloid burden, neuroinflammation, and links to cognitive decline after ischemic stroke.
Stroke 2014 Sep 8;45(9):2825-9. Epub 2014 Jul 8.
From the Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada (A.T.); Vulnerable Brain Laboratory, Department of Anatomy and Cell Biology (D.F.C., S.N.W.), and Department of Clinical Neurological Sciences, London Health Sciences Centre (V.H., S.N.W.), Western University, London, Ontario, Canada; and Max Planck Institute for Neurological Research, Cologne, Germany (W.-D.H.).

Comorbid Aβ toxicity and stroke: hippocampal atrophy, pathology, and cognitive deficit.
Neurobiol Aging 2014 Jul 8;35(7):1605-14. Epub 2014 Jan 8.
Department of Anatomy and Cell Biology, Canadian Institutes of Health Research Group on Vascular Cognitive Impairment, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.

Atrial fibrillation in patients with cryptogenic stroke.
N Engl J Med 2014 Jun;370(26):2467-77
From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., A.L., M.S., J.A.B., L.K.C., D.S., M. Mehdiratta, K.B., M.K.K.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, the University of Toronto Stroke Program (D.J.G.), Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute (D.J.G., R.A.), the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (D.J.G.), and the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital (V.P., K.E.T., J.H., H.V., A.L., M. Mamdani), Toronto, McMaster University, Hamilton, ON (M.S., D.J.S.), McGill University, Montreal (R.C.), University of Alberta, Edmonton (A.S., B.B.), Western University, London, ON (V.H., J.D.S.), Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB (S.B.C.), University of British Columbia, Vancouver (P.T., S.Y.), Queen's University, Kingston, ON (A.J.), Thunder Bay Regional Health Sciences Centre, Thunder Bay, ON (D.H.), Université Laval, Quebec City (S.V.), and Vancouver Island Health Research Centre, Victoria, BC (A.P.) - all in Canada; and the National University of Ireland, Galway (M.O.).



Proof-of-principle pilot study of oropharyngeal air-pulse application in individuals with dysphagia after hemispheric stroke.
Arch Phys Med Rehabil 2013 Jun 5;94(6):1088-94. Epub 2012 Dec 5.
Faculty of Health Sciences, School of Communication Sciences and Disorders, The University of Western Ontario, London, Ontario, Canada.

Impact of disability status on ischemic stroke costs in Canada in the first year.
Can J Neurol Sci 2012 Nov;39(6):793-800
Research Centre, Sunnybrook Health Sciences Centre Sunnybrook Health Sciences Centre, 2075 Bayview Aveune, E240, Toronto, Ontario, M4N 3M5, Canada.




Group-based exercise combined with dual-task training improves gait but not vascular health in active older adults without dementia.
Arch Gerontol Geriatr 2016 Mar-Apr;63:18-27. Epub 2015 Dec 2.
Health & Rehabilitation Sciences, Faculty of Health Sciences, Western University, London, ON, Canada; Lawson Health Research Institute, London, ON, Canada; Department of Family Medicine, Schulich School of Medicine & Dentistry, Western University, ON, Canada; Canadian Centre for Activity and Aging, Faculty of Health Sciences, Western University, London, ON, Canada; Department of Kinesiology, Faculty of Health Sciences, Western University, London, ON, Canada. Electronic address:

Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial).
Stroke 2016 12 15;47(12):2959-2965. Epub 2016 Nov 15.
From the Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University (L.A.S., V.H.), and Stroke, Dementia & Heart Disease Laboratory (L.A.S.), Ontario, Canada; Centre for Clinical Brain Sciences, University of Edinburgh, Scotland (G.C., J.M.W., P.S.); and George Institute for Global Health and Discipline of Medicine, University of Sydney, New South Wales, Australia (R.I.L.).


OF