Vladimir Hachinski

Vladimir Hachinski

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Vladimir Hachinski

Publications by authors named "Vladimir Hachinski"

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Impaired behavioural flexibility related to white matter microgliosis in the TgAPP21 rat model of Alzheimer disease.

Brain Behav Immun 2019 Feb 15. Epub 2019 Feb 15.

Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada; Department of Clinical Neurological Sciences, University Hospital, Western University, London, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2019.02.013DOI Listing
February 2019

Age, sex, and setting in the etiology of stroke study (ASSESS): Study design and protocol.

J Neurol Sci 2019 Feb 14;399:209-213. Epub 2019 Feb 14.

Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Center, Western University, ON, Canada; Department of Epidemiology and Biostatistics, Western University, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2019.02.024DOI Listing
February 2019

Evidence of Concomitantly Increasing Stroke and Dementia Prevalence among those 80 Years and Older in Ontario, Canada, 2003-04 to 2012-13.

Can J Neurol Sci 2019 Jan 19;46(1):105-107. Epub 2018 Nov 19.

1Department of Clinical Neurological Sciences,London Health Sciences Centre,Western University,London,Ontario,Canada.

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http://dx.doi.org/10.1017/cjn.2018.347DOI Listing
January 2019

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Alzheimers Dement 2019 Jan;15(1):158-167

Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338083PMC
January 2019

Dementia: new vistas and opportunities.

Neurol Sci 2019 Jan 21. Epub 2019 Jan 21.

Department of Clinical Neurological Sciences, Western University, 339 Windermere Road, London, Ontario, N6A 5A5, Canada.

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http://dx.doi.org/10.1007/s10072-019-3714-1DOI Listing
January 2019

Stroke-heart syndrome: clinical presentation and underlying mechanisms.

Lancet Neurol 2018 Dec 26;17(12):1109-1120. Epub 2018 Oct 26.

Klinik und Hochschulambulanz für Neurologie, Charité-Universitätsmedizin Berlin, Berlin, Germany; Berlin Institute of Health, Berlin, Germany; German Centre for Cardiovascular Research, Deutsches Zentrum für Herz-Kreislauf-Forschung, partner site Berlin, Berlin, Germany; German Center for Neurodegenerative Disease, Deutsches Zentrum für Herz-Kreislauf-Forschung, partner site Berlin, Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183033
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http://dx.doi.org/10.1016/S1474-4422(18)30336-3DOI Listing
December 2018

Anticoagulation Therapy for Atrial Fibrillation in Patients With Alzheimer's Disease.

Stroke 2018 Dec;49(12):2844-2850

From the Ivey Business School, University of Western Ontario, London, Canada (E.R.V., S.A.W.L., L.E.C.).

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http://dx.doi.org/10.1161/STROKEAHA.118.022596DOI Listing
December 2018

Stroke Prevention Strategies in the Developing World.

Stroke 2018 Dec;49(12):3092-3097

Department of Clinical Neurological Sciences, University of Western Ontario, Canada (V.H.).

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http://dx.doi.org/10.1161/STROKEAHA.118.017384DOI Listing
December 2018

Global, Regional, and Country-Specific Lifetime Risks of Stroke, 1990 and 2016.

Authors:
Valery L Feigin Grant Nguyen Kelly Cercy Catherine O Johnson Tahiya Alam Priyakumari G Parmar Amanuel A Abajobir Kalkidan H Abate Foad Abd-Allah Ayenew N Abejie Gebre Y Abyu Zanfina Ademi Gina Agarwal Muktar B Ahmed Rufus O Akinyemi Rajaa Al-Raddadi Leopold N Aminde Catherine Amlie-Lefond Hossein Ansari Hamid Asayesh Solomon W Asgedom Tesfay M Atey Henok T Ayele Maciej Banach Amitava Banerjee Aleksandra Barac Suzanne L Barker-Collo Till Bärnighausen Lars Barregard Sanjay Basu Neeraj Bedi Masoud Behzadifar Yannick Béjot Derrick A Bennett Isabela M Bensenor Derbew F Berhe Dube J Boneya Michael Brainin Ismael R Campos-Nonato Valeria Caso Carlos A Castañeda-Orjuela Jacquelin C Rivas Ferrán Catalá-López Hanne Christensen Michael H Criqui Albertino Damasceno Lalit Dandona Rakhi Dandona Kairat Davletov Barbora de Courten Gabrielle deVeber Klara Dokova Dumessa Edessa Matthias Endres Emerito J A Faraon Maryam S Farvid Florian Fischer Kyle Foreman Mohammad H Forouzanfar Seana L Gall Tsegaye T Gebrehiwot Johanna M Geleijnse Richard F Gillum Maurice Giroud Alessandra C Goulart Rahul Gupta Rajeev Gupta Vladimir Hachinski Randah R Hamadeh Graeme J Hankey Habtamu A Hareri Rasmus Havmoeller Simon I Hay Mohamed I Hegazy Desalegn T Hibstu Spencer L James Panniyammakal Jeemon Denny John Jost B Jonas Jacek Jóźwiak Rizwan Kalani Amit Kandel Amir Kasaeian Andre P Kengne Yousef S Khader Abdur R Khan Young-Ho Khang Jagdish Khubchandani Daniel Kim Yun J Kim Mika Kivimaki Yoshihiro Kokubo Dhaval Kolte Jacek A Kopec Soewarta Kosen Michael Kravchenko Rita Krishnamurthi G Anil Kumar Alessandra Lafranconi Pablo M Lavados Yirga Legesse Yongmei Li Xiaofeng Liang Warren D Lo Stefan Lorkowski Paulo A Lotufo Clement T Loy Mark T Mackay Hassan Magdy Abd El Razek Mahdi Mahdavi Azeem Majeed Reza Malekzadeh Deborah C Malta Abdullah A Mamun Lorenzo G Mantovani Sheila C O Martins Kedar K Mate Mohsen Mazidi Suresh Mehata Toni Meier Yohannes A Melaku Walter Mendoza George A Mensah Atte Meretoja Haftay B Mezgebe Tomasz Miazgowski Ted R Miller Norlinah M Ibrahim Shafiu Mohammed Ali H Mokdad Mahmood Moosazadeh Andrew E Moran Kamarul I Musa Ruxandra I Negoi Minh Nguyen Quyen L Nguyen Trang H Nguyen Tung T Tran Thanh T Nguyen Dina Nur Anggraini Ningrum Bo Norrving Jean J Noubiap Martin J O’Donnell Andrew T Olagunju Oyere K Onuma Mayowa O Owolabi Mahboubeh Parsaeian George C Patton Michael Piradov Martin A Pletcher Farshad Pourmalek V Prakash Mostafa Qorbani Mahfuzar Rahman Muhammad A Rahman Rajesh K Rai Annemarei Ranta David Rawaf Salman Rawaf Andre MN Renzaho Stephen R Robinson Ramesh Sahathevan Amirhossein Sahebkar Joshua A Salomon Paola Santalucia Itamar S Santos Benn Sartorius Aletta E Schutte Sadaf G Sepanlou Azadeh Shafieesabet Masood A Shaikh Morteza Shamsizadeh Kevin N Sheth Mekonnen Sisay Min-Jeong Shin Ivy Shiue Diego A S Silva Eugene Sobngwi Michael Soljak Reed J D Sorensen Luciano A Sposato Saverio Stranges Rizwan A Suliankatchi Rafael Tabarés-Seisdedos David Tanne Cuong Tat Nguyen J S Thakur Amanda G Thrift David L Tirschwell Roman Topor-Madry Bach X Tran Luong T Nguyen Thomas Truelsen Nikolaos Tsilimparis Stefanos Tyrovolas Kingsley N Ukwaja Olalekan A Uthman Yuri Varakin Tommi Vasankari Narayanaswamy Venketasubramanian Vasiliy V Vlassov Wenzhi Wang Andrea Werdecker Charles D A Wolfe Gelin Xu Yuichiro Yano Naohiro Yonemoto Chuanhua Yu Zoubida Zaidi Maysaa El Sayed Zaki Maigeng Zhou Boback Ziaeian Ben Zipkin Theo Vos Mohsen Naghavi Christopher J L Murray Gregory A Roth

N Engl J Med 2018 12;379(25):2429-2437

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http://www.nejm.org/doi/10.1056/NEJMoa1804492
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http://dx.doi.org/10.1056/NEJMoa1804492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247346PMC
December 2018

The convergence of stroke and dementia.

Arq Neuropsiquiatr 2018 Dec;76(12):849-852

Western University, Department of Clinical Neurological Sciences, London, Ontario, Canada.

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http://dx.doi.org/10.1590/0004-282X20180148DOI Listing
December 2018

Response to the growing dementia burden must be broader.

Lancet Neurol 2018 Nov;17(11):934

Department of Clinical Neurological Sciences, Western University, London, ON N6A 5A5, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422183036
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http://dx.doi.org/10.1016/S1474-4422(18)30361-2DOI Listing
November 2018

Air pollution: A silent common killer for stroke and dementia.

Int J Stroke 2018 10 3;13(7):667-668. Epub 2018 Jul 3.

1 Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Center, Western University, London, ON, Canada.

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http://dx.doi.org/10.1177/1747493018784476DOI Listing
October 2018

Implementing the proclamation of stroke and potentially preventable dementias.

J Clin Hypertens (Greenwich) 2018 Oct 9;20(10):1354-1359. Epub 2018 Oct 9.

Department of Neurology, Heidelberg University, Heidelberg, Germany.

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http://doi.wiley.com/10.1111/jch.13382
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http://dx.doi.org/10.1111/jch.13382DOI Listing
October 2018

Implementing the Proclamation of Stroke and Potentially Preventable Dementias.

Int J Stroke 2018 10;13(8):780-786

6 Department of Neurology, Heidelberg University, Heidelberg, Germany We are pleased to submit our commentary Implementing the Proclamation of Stroke and Potentially Treatable Preventable Dementias. As this has multidisciplinary implications for the World Stroke Organization, World Heart Federation, World Hypertension League and European Society of Hypertension, we are proposing publication in both International Journal of Stroke (World Stroke Organization) and Journal of Clinical Hypertension. Drs. Weber and Donnan are aware of this manuscript and have agreed to simultaneous publication.

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http://journals.sagepub.com/doi/10.1177/1747493018799965
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http://dx.doi.org/10.1177/1747493018799965DOI Listing
October 2018

Motor and Cognitive Trajectories Before Dementia: Results from Gait and Brain Study.

J Am Geriatr Soc 2018 Sep 2;66(9):1676-1683. Epub 2018 Apr 2.

Jewish General Hospital Memory Clinic, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/jgs.15341DOI Listing
September 2018

World dementia: One approach does not fit all.

Neurology 2018 Aug 11;91(6):264-270. Epub 2018 Jul 11.

From the Department of Neurology (S.A.), National Institute of Mental Health and Neurosciences, Bengaluru, India; and Department of Clinical Neurological Sciences (V.H.), University of Western Ontario, London, Canada.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005941DOI Listing
August 2018

APP21 transgenic rats develop age-dependent cognitive impairment and microglia accumulation within white matter tracts.

J Neuroinflammation 2018 Aug 28;15(1):241. Epub 2018 Aug 28.

Vulnerable Brain Laboratory, Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, 1151 Richmond St, London, Ontario, N6A 5C1, Canada.

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https://jneuroinflammation.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s12974-018-1273-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114740PMC
August 2018

ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.

Neurology 2018 Jun 11;90(24):e2127-e2134. Epub 2018 May 11.

From Rush Alzheimer's Disease Center (S.O., A.S.B., L.Y., J.F., C.G., J.A.S., D.A.B.) and Departments of Neurological Sciences (A.S.B., L.Y., J.A.S., D.A.B.) and Pathology (J.F., J.A.S.), Rush University Medical Center, Chicago, IL; Shariati Hospital (S.O.), Tehran University of Medical Sciences, Iran; Department of Geriatrics (J.F.), University of Sao Paulo Medical School, Brazil; University Hospital (V.H.), University of Western Ontario, London, Canada; Broad Institute (P.L.D.J.), Cambridge, MA; Center for Translational & Systems Neuroimmunology (P.L.D.J.), Department of Neurology, Columbia University Medical Center, New York, NY.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996834PMC
June 2018

B Vitamins for Stroke Prevention: Interaction of Low Platelet Count and High Plasma Total Homocysteine.

J Am Coll Cardiol 2018 May;71(19):2147-2148

Division of Neurology, Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2018.03.024DOI Listing
May 2018

Cerebrovascular and Alzheimer disease: fellow travelers or partners in crime?

J Neurochem 2018 03 25;144(5):513-516. Epub 2018 Jan 25.

Department of Clinical Neurological Science, University Hospital, the University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1111/jnc.14283DOI Listing
March 2018

Concomitant vascular and neurodegenerative pathologies double the risk of dementia.

Alzheimers Dement 2018 02 30;14(2):148-156. Epub 2017 Sep 30.

Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.07.755DOI Listing
February 2018

The vascular facet of late-onset Alzheimer's disease: an essential factor in a complex multifactorial disorder.

Curr Opin Neurol 2017 Dec;30(6):623-629

aMontreal Neurological InstitutebLudmer Center for NeuroInformatics and Mental Health, Montreal, QuebeccSchulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1097/WCO.0000000000000497DOI Listing
December 2017

The upgoing thumb sign: An interobserver/intraobserver reliability study.

Neurol Clin Pract 2017 Dec;7(6):483-487

Department of Clinical Neurological Sciences, University Hospital (SA, MRA, LS, VH), Stroke, Dementia and Heart Disease Laboratory, Department of Anatomy and Cell Biology (LS) and Department of Epidemiology and Biostatics (MRA, VH), the University of Western Ontario, London; Dr. Everett Chalmers Regional Hospital (SA), Fredericton Medical Clinic, Dalhousie University, New Brunswick, Canada; and Department of Neurology (MRA), Ghaem Hospital, Mashhad University of Medical Sciences, Iran.

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http://dx.doi.org/10.1212/CPJ.0000000000000398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800718PMC
December 2017

Comprehensive Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attack or Mild Stroke: PSYCHOLOGICAL PROFILE AND OUTCOMES.

J Cardiopulm Rehabil Prev 2017 Nov;37(6):428-436

Cardiac Rehabilitation and Secondary Prevention Program, St Joseph's Hospital, Ontario, Canada (Drs Prior and Suskin and Ms Unsworth); Clinical Neurological Sciences (Drs Hachinski, Chan, and Harnadek) and Southwestern Ontario Stroke Strategy (Ms Mytka), London Health Sciences Centre, Ontario, Canada; Lawson Health Research Institute, Ontario, Canada (Drs Prior and Suskin); Stroke Services, Cardiac Care Network of Ontario, Ontario, Canada (Ms O'Callaghan); and Western University, Ontario, Canada (Drs Hachinski, Chan, Harnadek, and Suskin).

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http://dx.doi.org/10.1097/HCR.0000000000000274DOI Listing
November 2017

Time is brain: Balancing risk in the treatment of presumed cardioembolic stroke.

J Neurol Sci 2017 Nov 21;382:157-160. Epub 2017 Jul 21.

Department of Clinical Neurological Sciences, University Hospital, London Health Science Center, The University of Western Ontario, Ontario, Canada; Department of Epidemiology & Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X173045
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http://dx.doi.org/10.1016/j.jns.2017.07.022DOI Listing
November 2017

Population-based stroke and dementia incidence trends: Age and sex variations.

Alzheimers Dement 2017 Oct 28;13(10):1081-1088. Epub 2017 Mar 28.

Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.02.010DOI Listing
October 2017

Blood pressure at age 60-65 versus age 70-75 and vascular dementia: a population based observational study.

BMC Geriatr 2017 10 27;17(1):252. Epub 2017 Oct 27.

Department of Medicine, Physiology and Pharmacology and Community Health Sciences, O'Brien Institute for Public Health and Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, AB, T2N 1N4, Canada.

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http://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-
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http://dx.doi.org/10.1186/s12877-017-0649-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658926PMC
October 2017

Inhibition of the primary motor cortex and the upgoing thumb sign.

eNeurologicalSci 2017 Sep 19;8:31-33. Epub 2017 Jul 19.

Department of Clinical Neurological Science, University Hospital, University of Western Ontario, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S24056502173002
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http://dx.doi.org/10.1016/j.ensci.2017.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730890PMC
September 2017

Behavioural inflexibility in a comorbid rat model of striatal ischemic injury and mutant hAPP overexpression.

Behav Brain Res 2017 08 8;333:267-275. Epub 2017 Jul 8.

Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, Western University, London ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.07.006DOI Listing
August 2017

Milder Alzheimer's disease pathology in heart failure and atrial fibrillation.

Alzheimers Dement 2017 Jul 5;13(7):770-777. Epub 2017 Feb 5.

Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jalz.2016.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592781PMC
July 2017

Association of Dual-Task Gait With Incident Dementia in Mild Cognitive Impairment: Results From the Gait and Brain Study.

JAMA Neurol 2017 07;74(7):857-865

Gait and Brain Lab, Parkwood Institute and Lawson Health Research Institute, London, Ontario, Canada10Faculty of Health Sciences, School of Kinesiology, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaneurol.2017.0643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710533PMC
July 2017

Upgoing thumb sign: A sensitive indicator of brain involvement?

Neurology 2017 Jul 28;89(4):370-375. Epub 2017 Jun 28.

From the Department of Clinical Neurological Sciences (V.H., R.A., M.R.A.), University Hospital, London Health Sciences Center, University of Western Ontario; Department of Epidemiology and Biostatistics (V.H., M.R.A.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; and Department of Neurology (M.R.A.), Ghaem Hospital, Mashhad University of Medical Sciences, Iran.

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http://dx.doi.org/10.1212/WNL.0000000000004157DOI Listing
July 2017

Optimisation of stroke research.

Lancet Neurol 2017 05;16(5):340-341

Department of Clinical Neurological Sciences, University Hospital, London Health Science Center, the University of Western Ontario, ON N6A 5A5, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30081-9DOI Listing
May 2017

Wounded brain, ailing heart: Central autonomic network disruption in acute stroke.

Ann Neurol 2017 Apr 3;81(4):495-497. Epub 2017 Apr 3.

Department of Clinical Neurological Sciences, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1002/ana.24911DOI Listing
April 2017

Stoop to conquer: preventing stroke and dementia together.

Lancet 2017 04;389(10078):1518

Western University, London, ON N6G 2N9, Canada. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30954-6DOI Listing
April 2017

Cost-effectiveness of cerebrospinal biomarkers for the diagnosis of Alzheimer's disease.

Alzheimers Res Ther 2017 Mar 16;9(1):18. Epub 2017 Mar 16.

Ivey Business School, Western University, 1255 Western Road, London, ON, N6G 0N1, Canada.

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http://dx.doi.org/10.1186/s13195-017-0243-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356269PMC
March 2017

Atherosclerosis and vascular cognitive impairment neuropathological guideline.

Brain 2017 02 21;140(2):e12. Epub 2016 Dec 21.

Department of Clinical Neurological Sciences, University Hospital, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1093/brain/aww304DOI Listing
February 2017

Henry J.M. Barnett, MD (1922-2016).

Neurology 2017 Feb;88(9):824-825

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http://dx.doi.org/10.1212/WNL.0000000000003668DOI Listing
February 2017

Henry J.M. Barnett: 1922-2016.

Stroke 2017 01 8;48(1):2-4. Epub 2016 Dec 8.

From the Stroke Prevention and Atherosclerosis Research Centre, Robarts Research Institute (J.D.S.) and Department of Clinical Neurological Sciences (J.D.S., V.H.), Western University, London, Canada.

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http://dx.doi.org/10.1161/STROKEAHA.116.015868DOI Listing
January 2017

Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial).

Stroke 2016 12 15;47(12):2959-2965. Epub 2016 Nov 15.

From the Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University (L.A.S., V.H.), and Stroke, Dementia & Heart Disease Laboratory (L.A.S.), Ontario, Canada; Centre for Clinical Brain Sciences, University of Edinburgh, Scotland (G.C., J.M.W., P.S.); and George Institute for Global Health and Discipline of Medicine, University of Sydney, New South Wales, Australia (R.I.L.).

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http://dx.doi.org/10.1161/STROKEAHA.116.014928DOI Listing
December 2016

Simple Neuropsychological Tests May Identify Participants in Whom Aspirin Use Is Associated With Lower Dementia Incidence: The Canadian Study of Health and Aging.

Am J Alzheimers Dis Other Demen 2016 11 24;31(7):545-550. Epub 2015 Dec 24.

Department of Clinical Neurological Sciences, University Hospital, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1177/1533317515619480DOI Listing
November 2016

Revising the ICD: stroke is a brain disease.

Lancet 2016 11 14;388(10059):2475-2476. Epub 2016 Oct 14.

University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1016/S0140-6736(16)31850-5DOI Listing
November 2016

Comparison of an Electronic and Paper-based Montreal Cognitive Assessment Tool.

Alzheimer Dis Assoc Disord 2015 Oct-Dec;29(4):325-9

*Ivey Business School §Department of Clinical Neurological Sciences, Schulich Medical School, Western University, London Departments of †Mathematics and Statistics ‡Computer Science, University of Windsor, Windsor, ON, Canada.

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http://dx.doi.org/10.1097/WAD.0000000000000069DOI Listing
September 2016

Stroke is a burdensome but preventable brain disorder.

Lancet Neurol 2016 08 9;15(9):892-893. Epub 2016 Jun 9.

Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, ON N6A5A5, Canada; Department of Neurology, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

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http://dx.doi.org/10.1016/S1474-4422(16)30120-XDOI Listing
August 2016

Group-based exercise combined with dual-task training improves gait but not vascular health in active older adults without dementia.

Arch Gerontol Geriatr 2016 Mar-Apr;63:18-27. Epub 2015 Dec 2.

Health & Rehabilitation Sciences, Faculty of Health Sciences, Western University, London, ON, Canada; Lawson Health Research Institute, London, ON, Canada; Department of Family Medicine, Schulich School of Medicine & Dentistry, Western University, ON, Canada; Canadian Centre for Activity and Aging, Faculty of Health Sciences, Western University, London, ON, Canada; Department of Kinesiology, Faculty of Health Sciences, Western University, London, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.archger.2015.11.008DOI Listing
July 2016

A comparison between the MoCA and the MMSE visuoexecutive sub-tests in detecting abnormalities in TIA/stroke patients.

Int J Stroke 2016 06 10;11(4):420-4. Epub 2016 Feb 10.

Stroke Prevention Research Unit, Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK Oxford NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1177/1747493016632238DOI Listing
June 2016

Preventing both stroke and dementia.

Lancet Neurol 2016 06 9;15(7):659. Epub 2016 May 9.

Department of Medicine, University Health Network, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S1474-4422(16)30041-2DOI Listing
June 2016

Human cerebral circuitry related to cardiac control: A neuroimaging meta-analysis.

Ann Neurol 2016 May 5;79(5):709-716. Epub 2016 Apr 5.

Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1002/ana.24642DOI Listing
May 2016

The Healthy Mind, Healthy Mobility Trial: A Novel Exercise Program for Older Adults.

Med Sci Sports Exerc 2016 Feb;48(2):297-306

1Department of Family Medicine, Western University, London, ON, CANADA; 2Aging, Rehabilitation & Geriatric Care Research Centre, Lawson Health Research Institute, London, ON, CANADA; 3Department of Epidemiology & National Alzheimer's Coordinating Center, University of Washington, Seattle, WA; 4School of Health and Rehabilitation Sciences, Western University, London, ON, CANADA; 5Department of Epidemiology & Biostatistics, Western University, London, ON, CANADA; 6Robarts Clinical Trials of Robarts Research Institute, Western University, London, ON, CANADA; 7Department of Physical Therapy, University of British Columbia, Vancouver, BC, CANADA; 8Djavad Mowafaghian Centre for Brain Health, Vancouver, BC, CANADA; 9Faculty of Education, Mie University, JAPAN; 10Department of Clinical Neurological Sciences, Western University, London, ON, CANADA; 11Canadian Centre for Activity and Aging, Faculty of Health Sciences, Western University, London, ON, CANADA; and 12School of Kinesiology, Western University, London, ON, CANADA.

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http://https://insights.ovid.com/crossref?an=00005768-201602
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http://dx.doi.org/10.1249/MSS.0000000000000758DOI Listing
February 2016

Careers in neurology in a globalizing world.

Neurology 2016 Jan;86(2):e21-3

From the Department of CNS, University of Western Ontario, London, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000002267DOI Listing
January 2016

Declining Incidence of Stroke and Dementia: Coincidence or Prevention Opportunity?

JAMA Neurol 2015 Dec;72(12):1529-31

Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaneurol.2015.2816DOI Listing
December 2015

Stroke and Potentially Preventable Dementias Proclamation: Updated World Stroke Day Proclamation.

Stroke 2015 Nov;46(11):3039-40

From the Department of Clinical Neurological Sciences, University of Western Ontario, 339 Windermere Rd, London, Ontario, Canada N6A 5A5. E-mail

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http://dx.doi.org/10.1161/STROKEAHA.115.011237DOI Listing
November 2015

World stroke day proclamation: updated.

Int J Stroke 2015 Oct;10 Suppl A100:2-3

Department of CNS, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1111/ijs.12638DOI Listing
October 2015

Neurovascular Units: A New Cost Effective Model?

Can J Neurol Sci 2015 Sep;42(5):281-2

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September 2015

Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and TIA: a systematic review and meta-analysis.

Int J Stroke 2015 Aug 6;10(6):801-7. Epub 2015 Jul 6.

Stroke Outcomes Research Center, Division of Neurology, Department of Medicine, St. Michael's Hospital and Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/ijs.12555DOI Listing
August 2015

Executive dysfunction in patients with transient ischemic attack and minor stroke.

J Neurol Sci 2015 Jul 23;354(1-2):17-20. Epub 2015 Apr 23.

Department of Clinical Neurological Sciences, London Health Sciences Centre, University Hospital, 339 Windermere Road, London, Ontario, N6A 5A5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2015.04.022DOI Listing
July 2015

Characterization of Behaviour and Remote Degeneration Following Thalamic Stroke in the Rat.

Int J Mol Sci 2015 Jun 17;16(6):13921-36. Epub 2015 Jun 17.

Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON N6A 5C1, Canada.

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http://dx.doi.org/10.3390/ijms160613921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490531PMC
June 2015

WORLD BRAIN MEETING The XXII World Congress of Neurology, Santiago, Chile: October 31 - November 5, 2015.

Can J Neurol Sci 2015 May;42(3):157-8

Western University,London Health Sciences Centre,London,Ontario,Canada.

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http://www.journals.cambridge.org/abstract_S0317167115000335
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http://dx.doi.org/10.1017/cjn.2015.33DOI Listing
May 2015

Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis.

Lancet Neurol 2015 Apr 4;14(4):377-87. Epub 2015 Mar 4.

Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, ON, Canada.

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http://dx.doi.org/10.1016/S1474-4422(15)70027-XDOI Listing
April 2015

Executive dysfunction is a strong stroke predictor.

J Neurol Sci 2015 Feb 13;349(1-2):161-7. Epub 2015 Jan 13.

Department of Clinical Neurological Sciences, University Hospital, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1016/j.jns.2015.01.010DOI Listing
February 2015

Nocturnal deterioration after ischemic stroke and autonomic dysfunction: hypothesis and implications.

Cerebrovasc Dis 2013 28;36(5-6):454-61. Epub 2013 Nov 28.

Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, Ont., Canada.

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http://dx.doi.org/10.1159/000356093DOI Listing
October 2014

Vitamin D and caudal primary motor cortex: a magnetic resonance spectroscopy study.

PLoS One 2014 31;9(1):e87314. Epub 2014 Jan 31.

Gait and Brain Lab, Lawson Health Research Institute, Parkwood Hospital, The University of Western Ontario, London, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909095PMC
October 2014

Baroreflex sensitivity: reliability of baroreflex components of the Valsalva maneuver.

Auton Neurosci 2014 Oct 14;185:138-40. Epub 2014 May 14.

Department of Clinical Neurological Sciences, University Hospital, London Health Sciences Centre, London, Ontario, Canada; Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.autneu.2014.05.002DOI Listing
October 2014

Association between gait variability and brain ventricle attributes: a brain mapping study.

Exp Gerontol 2014 Sep 24;57:256-63. Epub 2014 Jun 24.

Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, University Memory Clinic of Angers, UPRES EA 4638, University of Angers, UNAM, Angers, France.

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http://dx.doi.org/10.1016/j.exger.2014.06.015DOI Listing
September 2014

Amyloid burden, neuroinflammation, and links to cognitive decline after ischemic stroke.

Stroke 2014 Sep 8;45(9):2825-9. Epub 2014 Jul 8.

From the Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada (A.T.); Vulnerable Brain Laboratory, Department of Anatomy and Cell Biology (D.F.C., S.N.W.), and Department of Clinical Neurological Sciences, London Health Sciences Centre (V.H., S.N.W.), Western University, London, Ontario, Canada; and Max Planck Institute for Neurological Research, Cologne, Germany (W.-D.H.).

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http://dx.doi.org/10.1161/STROKEAHA.114.004285DOI Listing
September 2014

Comorbid Aβ toxicity and stroke: hippocampal atrophy, pathology, and cognitive deficit.

Neurobiol Aging 2014 Jul 8;35(7):1605-14. Epub 2014 Jan 8.

Department of Anatomy and Cell Biology, Canadian Institutes of Health Research Group on Vascular Cognitive Impairment, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.01.005DOI Listing
July 2014

Atrial fibrillation in patients with cryptogenic stroke.

N Engl J Med 2014 Jun;370(26):2467-77

From the Division of Neurology (D.J.G.), Department of Medicine (D.J.G., P.D., A.L., M.S., J.A.B., L.K.C., D.S., M. Mehdiratta, K.B., M.K.K.), and Dalla Lana School of Public Health (K.E.T.), University of Toronto, the University of Toronto Stroke Program (D.J.G.), Division of Neurology, Department of Medicine, and Brain Sciences Program, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute (D.J.G., R.A.), the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery (D.J.G.), and the Applied Health Research Centre, Li Ka Shing Knowledge Institute of St. Michael's Hospital (V.P., K.E.T., J.H., H.V., A.L., M. Mamdani), Toronto, McMaster University, Hamilton, ON (M.S., D.J.S.), McGill University, Montreal (R.C.), University of Alberta, Edmonton (A.S., B.B.), Western University, London, ON (V.H., J.D.S.), Department of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB (S.B.C.), University of British Columbia, Vancouver (P.T., S.Y.), Queen's University, Kingston, ON (A.J.), Thunder Bay Regional Health Sciences Centre, Thunder Bay, ON (D.H.), Université Laval, Quebec City (S.V.), and Vancouver Island Health Research Centre, Victoria, BC (A.P.) - all in Canada; and the National University of Ireland, Galway (M.O.).

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http://dx.doi.org/10.1056/NEJMoa1311376DOI Listing
June 2014

Preludes to brain failure: executive dysfunction and gait disturbances.

Neurol Sci 2014 Apr 24;35(4):601-4. Epub 2013 Dec 24.

Gait and Brain Lab, Division of Geriatric Medicine, Department of Medicine, Parkwood Hospital, The University of Western Ontario, Room A-280, 801 Commissioners Rd E, N6A 5A5, ON, London, Canada,

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http://dx.doi.org/10.1007/s10072-013-1613-4DOI Listing
April 2014

Poststroke atrial fibrillation: cause or consequence? Critical review of current views.

Neurology 2014 Apr 28;82(13):1180-6. Epub 2014 Feb 28.

From the Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, Canada.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000026
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http://dx.doi.org/10.1212/WNL.0000000000000265DOI Listing
April 2014

Thalamic cramplike pain.

J Neurol Sci 2014 Jan 27;336(1-2):269-72. Epub 2013 Oct 27.

Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.1016/j.jns.2013.10.026DOI Listing
January 2014

Cognitive health begins at conception: addressing dementia as a lifelong and preventable condition.

BMC Med 2013 Nov 19;11:246. Epub 2013 Nov 19.

Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 2QQ, UK.

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http://dx.doi.org/10.1186/1741-7015-11-246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832877PMC
November 2013

Dementia: from muddled diagnoses to treatable mechanisms.

Brain 2013 Sep;136(Pt 9):2652-4

Department of Clinical Neurological Sciences, Western University, London, Canada.

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http://dx.doi.org/10.1093/brain/awt230DOI Listing
September 2013

World Federation of Neurology: moving into the future.

Can J Neurol Sci 2013 Jul;40(4):609-11

Western University, London, Ontario, Canada.

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July 2013

Genetic determinants of "cognitive impairment, no dementia".

J Alzheimers Dis 2013 ;33(3):831-40

Department of Biochemistry, Schulich School of Medicine and Dentistry, Robarts Research Institute, University of Western Ontario, London, ON, Canada.

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http://dx.doi.org/10.3233/JAD-2012-121477DOI Listing
June 2013

Proof-of-principle pilot study of oropharyngeal air-pulse application in individuals with dysphagia after hemispheric stroke.

Arch Phys Med Rehabil 2013 Jun 5;94(6):1088-94. Epub 2012 Dec 5.

Faculty of Health Sciences, School of Communication Sciences and Disorders, The University of Western Ontario, London, Ontario, Canada.

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http://dx.doi.org/10.1016/j.apmr.2012.11.033DOI Listing
June 2013

Neurology in a globalizing world: World Congress of Neurology, Vienna, 2013.

Neurology 2013 Jun;80(24):2248-9

World Federation of Neurology, c/o Western University, London, Canada.

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http://dx.doi.org/10.1212/WNL.0b013e318296ea48DOI Listing
June 2013

Antihypertensive treatment can prevent stroke and cognitive decline.

Nat Rev Neurol 2013 03 18;9(3):174-8. Epub 2012 Dec 18.

Department of Clinical Neurological Sciences, London Health Sciences Centre, 339 Windermere Road, London, ON N6A 5A5, Canada.

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http://www.nature.com/articles/nrneurol.2012.255
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http://dx.doi.org/10.1038/nrneurol.2012.255DOI Listing
March 2013

Motor cortex and gait in mild cognitive impairment: a magnetic resonance spectroscopy and volumetric imaging study.

Brain 2013 Mar;136(Pt 3):859-71

FRCPC, Gait and Brain Laboratory, Parkwood Hospital, Division of Geriatric Medicine, Room A-280, 801 Commissioners Rd E., London, Ontario, Canada N6A 5A5.

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http://dx.doi.org/10.1093/brain/aws373DOI Listing
March 2013

Vitamin D concentration and lateral cerebral ventricle volume in older adults.

Mol Nutr Food Res 2013 Feb 20;57(2):267-76. Epub 2012 Dec 20.

Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, University Memory Clinic of Angers, UPRES EA 4638, University of Angers, UNAM, Angers, France.

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http://dx.doi.org/10.1002/mnfr.201200418DOI Listing
February 2013

Goodbye neurological examination, hello history?

Ann Neurol 2012 Dec;72(6):983

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http://dx.doi.org/10.1002/ana.23742DOI Listing
December 2012

Impact of disability status on ischemic stroke costs in Canada in the first year.

Can J Neurol Sci 2012 Nov;39(6):793-800

Research Centre, Sunnybrook Health Sciences Centre Sunnybrook Health Sciences Centre, 2075 Bayview Aveune, E240, Toronto, Ontario, M4N 3M5, Canada.

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November 2012

Therapeutic benefit of internet-based lifestyle counselling for hypertension.

Can J Cardiol 2012 May 11;28(3):390-6. Epub 2012 Apr 11.

Behavioural Cardiology Research Unit, University Health Network, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S0828282X120010
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http://dx.doi.org/10.1016/j.cjca.2012.02.012DOI Listing
May 2012

Cardiovascular and neurological causes of sudden death after ischaemic stroke.

Lancet Neurol 2012 Feb;11(2):179-88

Department of Clinical Neurological Sciences, London Health Sciences Centre, University of Western Ontario, London, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S14744422117029
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http://dx.doi.org/10.1016/S1474-4422(11)70291-5DOI Listing
February 2012