Vladimir B Seplyarskiy

Vladimir B Seplyarskiy

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Vladimir B Seplyarskiy

Vladimir B Seplyarskiy

Publications by authors named "Vladimir B Seplyarskiy"

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14Publications

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Human mismatch repair system balances mutation rates between strands by removing more mismatches from the lagging strand.

Genome Res 2017 08 16;27(8):1336-1343. Epub 2017 May 16.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow 127994, Russia.

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http://dx.doi.org/10.1101/gr.219915.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538550PMC
August 2017

Evolution of Local Mutation Rate and Its Determinants.

Mol Biol Evol 2017 05;34(5):1100-1109

Sector for Molecular Evolution, Institute for Information Transmission Problems of the RAS (Kharkevich Institute), Moscow, Russia.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msx060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850301PMC
May 2017

APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context.

Genome Res 2017 02 9;27(2):175-184. Epub 2016 Dec 9.

Institute for Information Transmission Problems of the Russian Academy of Sciences (Kharkevich Institute), Moscow 127994, Russia.

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http://dx.doi.org/10.1101/gr.210336.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287224PMC
February 2017

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.

Genome Res 2016 Feb 11;26(2):174-82. Epub 2016 Jan 11.

Department of Genetic Medicine and Development, University of Geneva Medical School, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland; Service of Genetic Medicine, University Hospitals of Geneva, 1211 Geneva, Switzerland.

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http://dx.doi.org/10.1101/gr.197046.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728370PMC
February 2016

Polymerase ζ Activity Is Linked to Replication Timing in Humans: Evidence from Mutational Signatures.

Mol Biol Evol 2015 Dec 15;32(12):3158-72. Epub 2015 Sep 15.

Institute of Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow, Russia Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia

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http://dx.doi.org/10.1093/molbev/msv184DOI Listing
December 2015

Extraordinary Genetic Diversity in a Wood Decay Mushroom.

Mol Biol Evol 2015 Oct 10;32(10):2775-83. Epub 2015 Jul 10.

School of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia Department of Ecology and Evolutionary Biology, University of Michigan

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http://dx.doi.org/10.1093/molbev/msv153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576712PMC
October 2015

Gene age predicts the strength of purifying selection acting on gene expression variation in humans.

Am J Hum Genet 2014 Dec;95(6):660-74

Department of Genetic Medicine and Development, University of Geneva Medical School, 1 Rue Michel-Servet, 1211 Geneva, Switzerland; Institute of Genetics and Genomics in Geneva, 1211 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259975PMC
December 2014

Prevalence of multinucleotide replacements in evolution of primates and Drosophila.

Mol Biol Evol 2013 Jun 27;30(6):1315-25. Epub 2013 Feb 27.

Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/molbev/mst036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649671PMC
June 2013

Heterogeneity of the transition/transversion ratio in Drosophila and Hominidae genomes.

Mol Biol Evol 2012 Aug 15;29(8):1943-55. Epub 2012 Feb 15.

Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia.

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http://dx.doi.org/10.1093/molbev/mss071DOI Listing
August 2012