Vivien R Sutton

Vivien R Sutton

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Vivien R Sutton

Vivien R Sutton

Publications by authors named "Vivien R Sutton"

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25Publications

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Antigen-specific CD4 CD25 T cells induced by locally expressed ICOS-Ig: the role of Foxp3, Perforin, Granzyme B and IL-10 - an experimental study.

Transpl Int 2019 Nov 16;32(11):1203-1215. Epub 2019 Jul 16.

Department of Surgery, Austin Health, The University of Melbourne, Heidelberg, Vic., Australia.

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http://dx.doi.org/10.1111/tri.13474DOI Listing
November 2019

Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.

FEBS J 2016 Mar 22;283(5):947-61. Epub 2016 Jan 22.

Cancer Cell Death/Killer Cell Biology Laboratories, Peter MacCallum Cancer Centre, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/febs.13649DOI Listing
March 2016

Granzyme H is a novel protease expressed by human mast cells.

Int Arch Allergy Immunol 2014 21;165(1):68-74. Epub 2014 Oct 21.

Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden.

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http://dx.doi.org/10.1159/000368403DOI Listing
February 2015

A natural genetic variant of granzyme B confers lethality to a common viral infection.

PLoS Pathog 2014 Dec 11;10(12):e1004526. Epub 2014 Dec 11.

Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Crawley, Western Australia, Australia; Centre for Experimental Immunology, Lions Eye Institute, Nedlands, Western Australia, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1004526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263754PMC
December 2014

A colorimetric assay that specifically measures Granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-Bzl.

J Vis Exp 2014 Nov 28(93):e52419. Epub 2014 Nov 28.

Cancer Immunology Program, Peter MacCallum Cancer Centre;

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http://dx.doi.org/10.3791/52419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354391PMC
November 2014

Activated mouse B cells lack expression of granzyme B.

J Immunol 2012 Apr 16;188(8):3886-92. Epub 2012 Mar 16.

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria 3002, Australia.

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http://dx.doi.org/10.4049/jimmunol.1103285DOI Listing
April 2012

A novel role for granzymes in anti-tumor immunity.

Oncoimmunology 2012 Mar;1(2):219-221

Ludwig Maximilian University of Munich; Division of Clinical Pharmacology and Medical Clinic; Munich, Germany.

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http://www.tandfonline.com/doi/full/10.4161/onci.1.2.18102
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http://dx.doi.org/10.4161/onci.1.2.18102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377003PMC
March 2012

Cathepsin C limits acute viral infection independently of NK cell and CD8+ T-cell cytolytic function.

Immunol Cell Biol 2011 May 26;89(4):540-8. Epub 2010 Oct 26.

Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Western Australia, Australia.

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http://dx.doi.org/10.1038/icb.2010.115DOI Listing
May 2011

Proteases in lymphocyte killer function: redundancy, polymorphism and questions remaining.

Biol Chem 2010 Aug;391(8):873-9

Peter MacCallum Cancer Centre, Melbourne, Australia.

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https://www.degruyter.com/view/j/bchm.2010.391.issue-8/bc.20
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http://dx.doi.org/10.1515/BC.2010.088DOI Listing
August 2010

Cathepsin H is an additional convertase of pro-granzyme B.

J Biol Chem 2010 Jul 30;285(27):20514-9. Epub 2010 Apr 30.

Department of Biochemistry and Molecular Biology, Monash University, Clayton, 3800 Victoria, Australia.

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http://dx.doi.org/10.1074/jbc.M109.094573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2898313PMC
July 2010

Dihydrofuro[3,4-c]pyridinones as inhibitors of the cytolytic effects of the pore-forming glycoprotein perforin.

J Med Chem 2008 Dec;51(23):7614-24

Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.

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http://dx.doi.org/10.1021/jm801063nDOI Listing
December 2008

Measuring cell death mediated by cytotoxic lymphocytes or their granule effector molecules.

Methods 2008 Mar;44(3):241-9

Cancer Cell Death Laboratory, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne, Vic. 8006, Australia.

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http://dx.doi.org/10.1016/j.ymeth.2007.11.011DOI Listing
March 2008

Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.

J Cell Biol 2007 Feb 5;176(4):425-33. Epub 2007 Feb 5.

Cancer Immunology Program, Research Division, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia.

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http://dx.doi.org/10.1083/jcb.200609077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2063978PMC
February 2007

Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.

Diabetes 2006 Aug;55(8):2212-9

St. Vincent's Institute, 41 Victoria Parade, Fitzroy, Victoria, 3065, Australia.

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http://dx.doi.org/10.2337/db06-0129DOI Listing
August 2006

A critical role for granzyme B, in addition to perforin and TNFalpha, in alloreactive CTL-induced mouse pancreatic beta cell death.

Transplantation 2006 Jan;81(2):146-54

Cancer Immunology Program, Research Division, Peter MacCallum Cancer Centre, East Melbourne, Australia.

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http://dx.doi.org/10.1097/01.tp.0000191939.68451.d9DOI Listing
January 2006

A central role for Bid in granzyme B-induced apoptosis.

J Biol Chem 2005 Feb 1;280(6):4476-82. Epub 2004 Dec 1.

Cancer Cell Death, Gene Regulation, and Immune Signaling Laboratories, Cancer Immunology Program, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne, Victoria 8006.

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http://dx.doi.org/10.1074/jbc.M410985200DOI Listing
February 2005

Granzyme B: pro-apoptotic, antiviral and antitumor functions.

Curr Opin Immunol 2003 Oct;15(5):533-43

Cancer Immunology Program, Research Division, Peter MacCallum Cancer Centre, Locked Bag 1, A'Beckett Street, Melbourne 8006, Australia.

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http://dx.doi.org/10.1016/s0952-7915(03)00107-9DOI Listing
October 2003

Purification of natural killer cell cytotoxic granules for assaying target cell apoptosis.

J Immunol Methods 2003 May;276(1-2):59-68

The Cancer Immunology Research Laboratory, The Peter MacCallum Cancer Institute, Victoria, Melbourne, Australia.

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http://dx.doi.org/10.1016/s0022-1759(03)00077-2DOI Listing
May 2003

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

Immunity 2003 Mar;18(3):319-29

Cancer Immunology Program, Peter MacCallum Cancer Institute, Locked Bag 1, A'Beckett Street, 8006, Melbourne, Australia.

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http://dx.doi.org/10.1016/s1074-7613(03)00050-5DOI Listing
March 2003