Publications by authors named "Viviana Simon"

97Publications

COVID-19: Staging of a New Disease.

Cancer Cell 2020 11 10;38(5):594-597. Epub 2020 Oct 10.

Department of Anesthesiology, Perioperative and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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November 2020

Positive, again! What to make of "re-positive" SARS-CoV-2 molecular test results.

EBioMedicine 2020 Oct 22;60:103011. Epub 2020 Sep 22.

Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.

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October 2020

Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective.

Immunity 2020 Oct 24;53(4):852-863.e7. Epub 2020 Sep 24.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; The Andrew M. and Jane M. Bursky Center for Human Immunology & Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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October 2020

Serology assays to manage COVID-19.

Science 2020 06 15;368(6495):1060-1061. Epub 2020 May 15.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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June 2020

HIV protease cleaves the antiviral m6A reader protein YTHDF3 in the viral particle.

PLoS Pathog 2020 02 13;16(2):e1008305. Epub 2020 Feb 13.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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February 2020

Reply to Hasenkrug et al., "Different Biological Activities of Specific Interferon Alpha Subtypes".

mSphere 2019 07 24;4(4). Epub 2019 Jul 24.

Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, Zurich, Switzerland

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July 2019

Dose-Dependent Differences in HIV Inhibition by Different Interferon Alpha Subtypes While Having Overall Similar Biologic Effects.

mSphere 2019 02 13;4(1). Epub 2019 Feb 13.

Department of Infectious Diseases and Hospital Epidemiology, University Hospital of Zurich, Zurich, Switzerland

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February 2019

FACS-Mediated Isolation of Neuronal Cell Populations From Virus-Infected Human Embryonic Stem Cell-Derived Cerebral Organoid Cultures.

Curr Protoc Stem Cell Biol 2019 02 24;48(1):e65. Epub 2018 Oct 24.

Huffington Center for Cell-Based Research, Black Family Stem Cell Institute, Department of Cell, Developmental and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY.

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February 2019

IL-15 regulates susceptibility of CD4 T cells to HIV infection.

Proc Natl Acad Sci U S A 2018 10 26;115(41):E9659-E9667. Epub 2018 Sep 26.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029;

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October 2018

Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice.

J Virol 2018 10 26;92(20). Epub 2018 Sep 26.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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October 2018

Expression of HERV-K108 envelope interferes with HIV-1 production.

Virology 2017 09 9;509:52-59. Epub 2017 Jun 9.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; The Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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September 2017

The Structural Interface between HIV-1 Vif and Human APOBEC3H.

J Virol 2017 03 14;91(5). Epub 2017 Feb 14.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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March 2017

A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells.

Cell Rep 2016 10;17(5):1438-1452

Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Diabetes Center, University of California, San Francisco, San Francisco, CA 94143, USA; Innovative Genomics Initiative, University of California, Berkeley, Berkeley, CA 94720, USA; Divisions of Infectious Diseases and Rheumatology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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October 2016

Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes.

AIDS 2016 07;30(11):1723-9

aKwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) bHIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa cDepartment of Microbiology and Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, USA dCentre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa eRagon Institute of MGH, MIT and Harvard University, Cambridge, Massachusetts, USA fMax Planck Institute for Infection Biology, Chariteplatz, Berlin, Germany. *Kavidha Reddy and Marcel Ooms contributed equally to this work.

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July 2016

Identification of the HIV-1 Vif and Human APOBEC3G Protein Interface.

Cell Rep 2015 Dec 25;13(9):1789-99. Epub 2015 Nov 25.

The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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December 2015

HIV Vpu Interferes with NF-κB Activity but Not with Interferon Regulatory Factor 3.

J Virol 2015 Oct 15;89(19):9781-90. Epub 2015 Jul 15.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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October 2015

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape.

Nat Immunol 2015 Jun;16(6):546-53

Department of Microbiology, NYU School of Medicine, New York, New York, USA.

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June 2015

Origin of the HIV-1 group O epidemic in western lowland gorillas.

Proc Natl Acad Sci U S A 2015 Mar 2;112(11):E1343-52. Epub 2015 Mar 2.

Unité Mixte Internationale 233, Institut de Recherche pour le Développement, INSERM U1175, and University of Montpellier, 34394 Montpellier, France; Computational Biology Institute, 34095 Montpellier, France

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March 2015

Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner.

J Virol 2014 Jul 23;88(13):7528-40. Epub 2014 Apr 23.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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July 2014

HIV-1 Vpu antagonism of tetherin inhibits antibody-dependent cellular cytotoxic responses by natural killer cells.

J Virol 2014 Jun 12;88(11):6031-46. Epub 2014 Mar 12.

Division of Infectious Diseases, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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June 2014

Direct non-productive HIV-1 infection in a T-cell line is driven by cellular activation state and NFκB.

Retrovirology 2014 Feb 7;11:17. Epub 2014 Feb 7.

Department of Microbiology, The Global Health and Emerging Pathogens Institute; Mount Sinai School of Medicine, 1468 Madison Avenue, Annenberg building 18-50, New York, NY 10029, USA.

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February 2014

HIV-1 Vif adaptation to human APOBEC3H haplotypes.

Cell Host Microbe 2013 Oct;14(4):411-21

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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October 2013

APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host.

PLoS Pathog 2013 3;9(10):e1003641. Epub 2013 Oct 3.

Institut für Klinische und Molekulare Virologie, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen and Nuremberg, Germany ; Department of Biology, Boston College, Chestnut Hill, Massachusetts, United States of America.

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May 2014

Vif proteins from diverse primate lentiviral lineages use the same binding site in APOBEC3G.

J Virol 2013 Nov 28;87(21):11861-71. Epub 2013 Aug 28.

The Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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November 2013

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.

PLoS Pathog 2013 Mar 28;9(3):e1003265. Epub 2013 Mar 28.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

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March 2013

The resistance of human APOBEC3H to HIV-1 NL4-3 molecular clone is determined by a single amino acid in Vif.

PLoS One 2013 28;8(2):e57744. Epub 2013 Feb 28.

Department of Microbiology, Mount Sinai School of Medicine, New York, New York, United States of America.

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August 2013

A doubly fluorescent HIV-1 reporter shows that the majority of integrated HIV-1 is latent shortly after infection.

J Virol 2013 Apr 13;87(8):4716-27. Epub 2013 Feb 13.

Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

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April 2013

DENV inhibits type I IFN production in infected cells by cleaving human STING.

PLoS Pathog 2012 4;8(10):e1002934. Epub 2012 Oct 4.

Department of Microbiology and the Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York City, New York, United States of America.

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April 2013

APOBEC3A, APOBEC3B, and APOBEC3H haplotype 2 restrict human T-lymphotropic virus type 1.

J Virol 2012 Jun 28;86(11):6097-108. Epub 2012 Mar 28.

Department of Microbiology, Mount Sinai School of Medicine, New York, New York, USA.

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June 2012

Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors.

J Virol 2012 Mar 28;86(5):2874-7. Epub 2011 Dec 28.

Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, Minnesota, USA.

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March 2012

The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H.

J Virol 2012 Jan 19;86(1):49-59. Epub 2011 Oct 19.

Department of Microbiology, Mount Sinai School of Medicine, New York, New York, USA.

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January 2012

Identification and functional analysis of a second RBF-2 binding site within the HIV-1 promoter.

Virology 2011 Sep 2;418(1):57-66. Epub 2011 Aug 2.

Department of Biochemistry and Molecular Biology, Molecular Epigenetics, Life Sciences Institute, University of British Columbia, 2350 Health Sciences Mall, Vancouver, B.C. Canada.

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September 2011

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis.

Proc Natl Acad Sci U S A 2011 Apr 21;108(14):5777-82. Epub 2011 Mar 21.

Department of Microbiology, Department of Medicine, and Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York, NY 10029, USA.

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April 2011

Immune mechanisms of HIV control.

Curr Opin Immunol 2010 Aug;22(4):488-96

Institut Pasteur, Unité d'Immunogénétique Cellulaire, 25 rue du Dr Roux, 75724 Paris Cedex 15, France.

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August 2010

Moderate influence of human APOBEC3F on HIV-1 replication in primary lymphocytes.

J Virol 2010 Sep 30;84(18):9613-7. Epub 2010 Jun 30.

Mount Sinai School of Medicine, Department of Medicine, The Global Health and Emerging Pathogens Institute, New York, New York 10029, USA.

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September 2010

The localization of APOBEC3H variants in HIV-1 virions determines their antiviral activity.

J Virol 2010 Aug 2;84(16):7961-9. Epub 2010 Jun 2.

Division of Infectious Diseases, Department of Medicine, and Department of Microbiology, Global Health and Emerging Pathogens Institute, Mount Sinai School of Medicine, New York, New York 10029-6574, USA.

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August 2010

Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H.

J Virol 2009 Jan 22;83(1):295-303. Epub 2008 Oct 22.

Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1090, New York City, NY 10029, USA.

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January 2009

Cytidine deamination induced HIV-1 drug resistance.

Proc Natl Acad Sci U S A 2008 Apr 7;105(14):5501-6. Epub 2008 Apr 7.

Department of Medicine, Division of Infectious Diseases, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1090, New York, NY 10029, USA.

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April 2008

Characterization of HIV-1 integrase N-terminal mutant viruses.

Virology 2007 Mar 14;360(1):129-35. Epub 2006 Nov 14.

The Aaron Diamond AIDS Research Center 455 First Avenue, New York, NY 10016, USA.

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March 2007

HIV/AIDS epidemiology, pathogenesis, prevention, and treatment.

Lancet 2006 Aug;368(9534):489-504

Aaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, USA.

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August 2006

Progestin-based contraceptive suppresses cellular immune responses in SHIV-infected rhesus macaques.

Virology 2006 Aug 30;352(1):169-77. Epub 2006 May 30.

Aaron Diamond AIDS Research Center, The Rockefeller University, 455 First Ave, 7th Floor, New York, NY 10016, USA.

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August 2006

Sex and gender differences in pain and inflammation: a rapidly maturing field.

Am J Physiol Regul Integr Comp Physiol 2006 Aug 4;291(2):R241-4. Epub 2006 May 4.

Program in Neuroscience, Florida State University, Tallahassee, FL 32306-1270, USA.

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August 2006

Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification.

PLoS Pathog 2005 Sep 22;1(1):e6. Epub 2005 Jul 22.

Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York, United States of America.

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September 2005

Wanted: women in clinical trials.

Authors:
Viviana Simon

Science 2005 Jun;308(5728):1517

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June 2005

HIV-1 dynamics in vivo: implications for therapy.

Nat Rev Microbiol 2003 Dec;1(3):181-90

Aaron Diamond AIDS Research Center, Rockefeller University, 455 First Avenue, New York, New York 10016, USA.

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December 2003

Determining the relative efficacy of highly active antiretroviral therapy.

J Infect Dis 2003 Mar 6;187(6):896-900. Epub 2003 Mar 6.

Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York, NY 10016, USA.

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March 2003