Publications by authors named "Vivian Y Shin"

50Publications

Germline Mutation in 1338 BRCA-Negative Chinese Hereditary Breast and/or Ovarian Cancer Patients: Clinical Testing with a Multigene Test Panel.

J Mol Diagn 2020 04 15;22(4):544-554. Epub 2020 Feb 15.

Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong Sanatorium and Hospital, Hong Kong Special Administrative Region; Division of Molecular Pathology, Department of Pathology, Hong Kong Sanatorium and Hospital, Hong Kong Special Administrative Region.

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http://dx.doi.org/10.1016/j.jmoldx.2020.01.013DOI Listing
April 2020

Competing Risk Analyses of Medullary Carcinoma of Breast in Comparison to Infiltrating Ductal Carcinoma.

Sci Rep 2020 01 17;10(1):560. Epub 2020 Jan 17.

Department of Medical Oncology, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1038/s41598-019-57168-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969020PMC
January 2020

Association of Genomic Domains in and with Prostate Cancer Risk and Aggressiveness.

Authors:
Vivek L Patel Evan L Busch Tara M Friebel Angel Cronin Goska Leslie Lesley McGuffog Julian Adlard Simona Agata Bjarni A Agnarsson Munaza Ahmed Kristiina Aittomäki Elisa Alducci Irene L Andrulis Adalgeir Arason Norbert Arnold Grazia Artioli Brita Arver Bernd Auber Jacopo Azzollini Judith Balmaña Rosa B Barkardottir Daniel R Barnes Alicia Barroso Daniel Barrowdale Muriel Belotti Javier Benitez Birgitte Bertelsen Marinus J Blok Istvan Bodrogi Valérie Bonadona Bernardo Bonanni Davide Bondavalli Susanne E Boonen Julika Borde Ake Borg Angela R Bradbury Angela Brady Carole Brewer Joan Brunet Bruno Buecher Saundra S Buys Santiago Cabezas-Camarero Trinidad Caldés Almuth Caliebe Maria A Caligo Mariarosaria Calvello Ian G Campbell Ileana Carnevali Estela Carrasco Tsun L Chan Annie T W Chu Wendy K Chung Kathleen B M Claes Gemo Study Collaborators Embrace Collaborators Jackie Cook Laura Cortesi Fergus J Couch Mary B Daly Giuseppe Damante Esther Darder Rosemarie Davidson Miguel de la Hoya Lara Della Puppa Joe Dennis Orland Díez Yuan Chun Ding Nina Ditsch Susan M Domchek Alan Donaldson Bernd Dworniczak Douglas F Easton Diana M Eccles Rosalind A Eeles Hans Ehrencrona Bent Ejlertsen Christoph Engel D Gareth Evans Laurence Faivre Ulrike Faust Lídia Feliubadaló Lenka Foretova Florentia Fostira George Fountzilas Debra Frost Vanesa García-Barberán Pilar Garre Marion Gauthier-Villars Lajos Géczi Andrea Gehrig Anne-Marie Gerdes Paul Gesta Giuseppe Giannini Gord Glendon Andrew K Godwin David E Goldgar Mark H Greene Angelica M Gutierrez-Barrera Eric Hahnen Ute Hamann Jan Hauke Natalie Herold Frans B L Hogervorst Ellen Honisch John L Hopper Peter J Hulick KConFab Investigators Hebon Investigators Louise Izatt Agnes Jager Paul James Ramunas Janavicius Uffe Birk Jensen Thomas Dyrso Jensen Oskar Th Johannsson Esther M John Vijai Joseph Eunyoung Kang Karin Kast Johanna I Kiiski Sung-Won Kim Zisun Kim Kwang-Pil Ko Irene Konstantopoulou Gero Kramer Lotte Krogh Torben A Kruse Ava Kwong Mirjam Larsen Christine Lasset Charlotte Lautrup Conxi Lazaro Jihyoun Lee Jong Won Lee Min Hyuk Lee Johannes Lemke Fabienne Lesueur Annelie Liljegren Annika Lindblom Patricia Llovet Adria Lopez-Fernández Irene Lopez-Perolio Victor Lorca Jennifer T Loud Edmond S K Ma Phuong L Mai Siranoush Manoukian Veronique Mari Lynn Martin Laura Matricardi Noura Mebirouk Veronica Medici Hanne E J Meijers-Heijboer Alfons Meindl Arjen R Mensenkamp Clare Miller Denise Molina Gomes Marco Montagna Thea M Mooij Lidia Moserle Emmanuelle Mouret-Fourme Anna Marie Mulligan Katherine L Nathanson Marie Navratilova Heli Nevanlinna Dieter Niederacher Finn C Cilius Nielsen Liene Nikitina-Zake Kenneth Offit Edith Olah Olufunmilayo I Olopade Kai-Ren Ong Ana Osorio Claus-Eric Ott Domenico Palli Sue K Park Michael T Parsons Inge Sokilde Pedersen Bernard Peissel Ana Peixoto Pedro Pérez-Segura Paolo Peterlongo Annabeth Høgh Petersen Mary E Porteous Miguel Angel Pujana Paolo Radice Juliane Ramser Johanna Rantala Muhammad U Rashid Kerstin Rhiem Piera Rizzolo Mark E Robson Matti A Rookus Caroline M Rossing Kathryn J Ruddy Catarina Santos Claire Saule Rosa Scarpitta Rita K Schmutzler Hélène Schuster Leigha Senter Caroline M Seynaeve Payal D Shah Priyanka Sharma Vivian Y Shin Valentina Silvestri Jacques Simard Christian F Singer Anne-Bine Skytte Katie Snape Angela R Solano Penny Soucy Melissa C Southey Amanda B Spurdle Linda Steele Doris Steinemann Dominique Stoppa-Lyonnet Agostina Stradella Lone Sunde Christian Sutter Yen Y Tan Manuel R Teixeira Soo Hwang Teo Mads Thomassen Maria Grazia Tibiletti Marc Tischkowitz Silvia Tognazzo Amanda E Toland Stefania Tommasi Diana Torres Angela Toss Alison H Trainer Nadine Tung Christi J van Asperen Frederieke H van der Baan Lizet E van der Kolk Rob B van der Luijt Liselotte P van Hest Liliana Varesco Raymonda Varon-Mateeva Alessandra Viel Jeroen Vierstraete Roberta Villa Anna von Wachenfeldt Philipp Wagner Shan Wang-Gohrke Barbara Wappenschmidt Jeffrey N Weitzel Greet Wieme Siddhartha Yadav Drakoulis Yannoukakos Sook-Yee Yoon Cristina Zanzottera Kristin K Zorn Anthony V D'Amico Matthew L Freedman Mark M Pomerantz Georgia Chenevix-Trench Antonis C Antoniou Susan L Neuhausen Laura Ottini Henriette Roed Nielsen Timothy R Rebbeck

Cancer Res 2020 02 13;80(3):624-638. Epub 2019 Nov 13.

Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-1840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553241PMC
February 2020

Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer.

Cell Death Dis 2019 05 16;10(6):383. Epub 2019 May 16.

Laboratory of Cancer Biology, Key Laboratory of Biotherapy of Zhejiang Province, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1038/s41419-019-1585-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522595PMC
May 2019

Breast and ovarian cancer penetrance of mutations among Hong Kong women.

Oncotarget 2018 May 2;9(38):25025-25033. Epub 2018 Feb 2.

Department of Surgery, the University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.18632/oncotarget.24382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982775PMC
May 2018

Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis.

Mol Ther 2018 07 14;26(7):1828-1839. Epub 2018 Apr 14.

Laboratory of Cancer Biology, Key Lab of Zhejiang Biotherapy, Sir Run Run Shaw Hospital, Medical School of Zhejiang University, Hangzhou, China. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2018.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035735PMC
July 2018

miR-199a-5p confers tumor-suppressive role in triple-negative breast cancer.

BMC Cancer 2016 11 14;16(1):887. Epub 2016 Nov 14.

Breast Surgery Division, Department of Surgery, The University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1186/s12885-016-2916-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109692PMC
November 2016

Overexpression of GOLPH3 is associated with poor survival in Non-small-cell lung cancer.

Am J Transl Res 2016 15;8(4):1756-62. Epub 2016 Apr 15.

Department of Medical Oncology, Key Laboratory of Biotherapy in Zhejiang, Sir Runrun Shaw Hospital, Medical School of Zhejiang University China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859904PMC
May 2016

Detection of Germline Mutation in Hereditary Breast and/or Ovarian Cancers by Next-Generation Sequencing on a Four-Gene Panel.

J Mol Diagn 2016 07 5;18(4):580-94. Epub 2016 May 5.

Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong, People's Republic of China; Department of Molecular Pathology, Hong Kong Sanatorium & Hospital, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1016/j.jmoldx.2016.03.005DOI Listing
July 2016

Germline RECQL mutations in high risk Chinese breast cancer patients.

Breast Cancer Res Treat 2016 06 28;157(2):211-215. Epub 2016 Apr 28.

Women's College Research Institute, Women's College Hospital, Toronto, Canada.

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http://dx.doi.org/10.1007/s10549-016-3784-1DOI Listing
June 2016

Response to: Comment on 'Circulating cell-free miRNAs as biomarker for triple-negative breast cancer'.

Br J Cancer 2016 05 21;114(10):e6. Epub 2016 Apr 21.

Department of Surgery, The University of Hong Kong, Hong Kong, SAR.

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http://dx.doi.org/10.1038/bjc.2016.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4865970PMC
May 2016

A new paradigm of genetic testing for hereditary breast/ovarian cancers.

Hong Kong Med J 2016 Apr 14;22(2):171-7. Epub 2016 Mar 14.

Breast Surgery Division, The University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.12809/hkmj154634DOI Listing
April 2016

Association of EP2 receptor and SLC19A3 in regulating breast cancer metastasis.

Am J Cancer Res 2015 15;5(11):3389-99. Epub 2015 Oct 15.

Department of Surgery, The University of Hong KongHong Kong; Department of Surgery, The Hong Kong Sanatorium and HospitalHong Kong; The Hong Kong Hereditary Breast Cancer Family RegistryHong Kong.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697685PMC
January 2016

The importance of analysis of long-range rearrangement of BRCA1 and BRCA2 in genetic diagnosis of familial breast cancer.

Cancer Genet 2015 Sep 9;208(9):448-54. Epub 2015 Jun 9.

Department of Oncology, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1016/j.cancergen.2015.05.031DOI Listing
September 2015

Histone deacetylase 3 inhibits new tumor suppressor gene DTWD1 in gastric cancer.

Am J Cancer Res 2015 15;5(2):663-73. Epub 2015 Jan 15.

Laboratory of Cancer Biology, Department of Medical Oncology, Key laboratory of Biotherapy in Zhejiang Province, Sir Runrun Shaw Hospital Zhejiang University, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396045PMC
May 2015

MicroRNAs are differentially deregulated in mammary malignant phyllodes tumour.

Histopathology 2015 Sep 2;67(3):294-305. Epub 2015 Mar 2.

Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/his.12648DOI Listing
September 2015

Epigenetic silencing of miR-490-3p reactivates the chromatin remodeler SMARCD1 to promote Helicobacter pylori-induced gastric carcinogenesis.

Cancer Res 2015 Feb 12;75(4):754-65. Epub 2014 Dec 12.

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong. Institute of Digestive Disease and State Key Laboratory of Digestive Disease, The Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1301DOI Listing
February 2015

Elevation of methylated DNA in KILLIN/PTEN in the plasma of patients with thyroid and/or breast cancer.

Onco Targets Ther 2014 11;7:2085-92. Epub 2014 Nov 11.

Department of Surgery, The University of Hong Kong, Hong Kong ; Hong Kong Hereditary Breast Cancer Family Registry, Hong Kong.

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http://dx.doi.org/10.2147/OTT.S53597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234161PMC
November 2014

Animal models of gastrointestinal inflammation and cancer.

Life Sci 2014 Jul 11;108(1):1-6. Epub 2014 May 11.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2014.04.036DOI Listing
July 2014

MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells.

Tumour Biol 2014 Mar 13;35(3):2591-8. Epub 2013 Nov 13.

Department of Surgery, The University of Hong Kong, Hong Kong SAR, Hong Kong.

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http://link.springer.com/10.1007/s13277-013-1341-7
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http://dx.doi.org/10.1007/s13277-013-1341-7DOI Listing
March 2014

Nicotine and gastrointestinal disorders: its role in ulceration and cancer development.

Curr Pharm Des 2013 ;19(1):5-10

Department of Surgery, Faculty of Medicine, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.2174/13816128130103DOI Listing
June 2013

Effects of adrenaline in human colon adenocarcinoma HT-29 cells.

Life Sci 2011 Jun 30;88(25-26):1108-12. Epub 2011 Apr 30.

Department of Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong, China.

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https://linkinghub.elsevier.com/retrieve/pii/S00243205110019
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http://dx.doi.org/10.1016/j.lfs.2011.04.007DOI Listing
June 2011

NF-κB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors.

Carcinogenesis 2011 Feb 15;32(2):240-5. Epub 2010 Nov 15.

Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://dx.doi.org/10.1093/carcin/bgq240DOI Listing
February 2011

Probiotic Lactobacillus rhamnosus GG enhances gastric ulcer healing in rats.

Eur J Pharmacol 2007 Jun 7;565(1-3):171-9. Epub 2007 Mar 7.

Department of Pharmacology, The University of Hong Kong, China.

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http://linkinghub.elsevier.com/retrieve/pii/S001429990700254
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http://dx.doi.org/10.1016/j.ejphar.2007.02.050DOI Listing
June 2007

The cationic host defense peptide rCRAMP promotes gastric ulcer healing in rats.

J Pharmacol Exp Ther 2006 Aug 2;318(2):547-54. Epub 2006 May 2.

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China.

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http://dx.doi.org/10.1124/jpet.106.102467DOI Listing
August 2006

Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice.

Int J Med Sci 2006 1;3(1):1-6. Epub 2006 Jan 1.

Centre of Infection and Immunology and Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1332197PMC
http://dx.doi.org/10.7150/ijms.3.1DOI Listing
June 2007

Nicotine induces cyclooxygenase-2 and vascular endothelial growth factor receptor-2 in association with tumor-associated invasion and angiogenesis in gastric cancer.

Mol Cancer Res 2005 Nov;3(11):607-15

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, Hong Kong.

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http://dx.doi.org/10.1158/1541-7786.MCR-05-0106DOI Listing
November 2005

A mechanistic study of colon cancer growth promoted by cigarette smoke extract.

Eur J Pharmacol 2005 Sep;519(1-2):52-7

Department of Pharmacology, Faculty of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1016/j.ejphar.2005.07.009DOI Listing
September 2005

Nicotine and gastric cancer.

Alcohol 2005 Apr;35(3):259-64

Centre of Infection and Immunology and Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, HKSAR, China.

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http://dx.doi.org/10.1016/j.alcohol.2005.04.007DOI Listing
April 2005

Cyclooxygenase-2 in cancer cells and macrophages induces colon cancer cell growth by cigarette smoke extract.

Eur J Pharmacol 2005 Jul;518(1):47-55

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong SAR, China.

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http://dx.doi.org/10.1016/j.ejphar.2005.05.018DOI Listing
July 2005

Nicotine promotes gastric tumor growth and neovascularization by activating extracellular signal-regulated kinase and cyclooxygenase-2.

Carcinogenesis 2004 Dec 19;25(12):2487-95. Epub 2004 Aug 19.

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, HKSAR, China.

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http://dx.doi.org/10.1093/carcin/bgh266DOI Listing
December 2004

The modulating role of nuclear factor-kappaB in the action of alpha7-nicotinic acetylcholine receptor and cross-talk between 5-lipoxygenase and cyclooxygenase-2 in colon cancer growth induced by 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.

J Pharmacol Exp Ther 2004 Oct 25;311(1):123-30. Epub 2004 May 25.

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 1/F Li Shu Fan Bldg., 5 Sassoon Rd., Hong Kong, China.

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http://dx.doi.org/10.1124/jpet.104.068031DOI Listing
October 2004

A mechanistic study of cigarette smoke and cyclooxygenase-2 on proliferation of gastric cancer cells.

Toxicol Appl Pharmacol 2004 Feb;195(1):103-12

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong HKSAR, China.

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http://dx.doi.org/10.1016/j.taap.2003.10.009DOI Listing
February 2004

Dexamethasone delays ulcer healing by inhibition of angiogenesis in rat stomachs.

Eur J Pharmacol 2004 Feb;485(1-3):275-81

Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital and National Yang-Ming University, School of Medicine, Taiwan.

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http://dx.doi.org/10.1016/j.ejphar.2003.11.038DOI Listing
February 2004

Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway.

J Pharmacol Exp Ther 2004 Jan 20;308(1):66-72. Epub 2003 Oct 20.

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1124/jpet.103.058321DOI Listing
January 2004

Non-ulcerogenic dose of dexamethasone delays gastric ulcer healing in rats.

J Pharmacol Exp Ther 2003 Nov 9;307(2):692-8. Epub 2003 Sep 9.

Department of Pharmacology, Faculty of Medicine, 2nd Floor, Laboratory Block, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China.

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http://dx.doi.org/10.1124/jpet.103.055202DOI Listing
November 2003

Cigarette smoke exposure increases ulcerative colitis-associated colonic adenoma formation in mice.

Carcinogenesis 2003 Aug 5;24(8):1407-13. Epub 2003 Jun 5.

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1093/carcin/bgg094DOI Listing
August 2003

Involvement of bcl-2 and caspase-3 in apoptosis induced by cigarette smoke extract in the gastric epithelial cell.

Toxicol Pathol 2003 Mar-Apr;31(2):220-6

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, HKSAR, China.

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http://dx.doi.org/10.1080/01926230390183715DOI Listing
October 2003

Morphine as a drug for stress ulcer prevention and healing in the stomach.

Eur J Pharmacol 2003 Jan;460(2-3):177-82

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China.

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http://dx.doi.org/10.1016/s0014-2999(02)02922-9DOI Listing
January 2003

Nicotine suppresses gastric wound repair via the inhibition of polyamine and K(+) channel expression.

Eur J Pharmacol 2002 May;444(1-2):115-21

Department of Pharmacology, Faculty of Medicine, University of Hong Kong, 1/F Li Shu Fan Building, 5 Sassoon Road, HKSAR, Hong Kong, China.

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http://dx.doi.org/10.1016/s0014-2999(02)01610-2DOI Listing
May 2002

Cigarette smoke extracts delay wound healing in the stomach: involvement of polyamine synthesis.

Exp Biol Med (Maywood) 2002 Feb;227(2):114-24

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, HKSAR, China.

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http://dx.doi.org/10.1177/153537020222700206DOI Listing
February 2002

Pathogenesis of nicotine treatment and its withdrawal on stress-induced gastric ulceration in rats.

Eur J Pharmacol 2002 Jan;434(1-2):81-6

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, 1/F, Li Shu Fan Building, 5 Sassoon Road, Hong Kong, PR China.

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http://dx.doi.org/10.1016/s0014-2999(01)01529-1DOI Listing
January 2002